BRPI0814363A2 - Produtos fármacos de interferon de liberação controlada e tratamento de infecção por hcv usando os mesmos - Google Patents
Produtos fármacos de interferon de liberação controlada e tratamento de infecção por hcv usando os mesmosInfo
- Publication number
- BRPI0814363A2 BRPI0814363A2 BRPI0814363-3A2A BRPI0814363A BRPI0814363A2 BR PI0814363 A2 BRPI0814363 A2 BR PI0814363A2 BR PI0814363 A BRPI0814363 A BR PI0814363A BR PI0814363 A2 BRPI0814363 A2 BR PI0814363A2
- Authority
- BR
- Brazil
- Prior art keywords
- interferon
- same
- controlled release
- hcv infection
- release drug
- Prior art date
Links
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 238000013270 controlled release Methods 0.000 title 1
- 229940126534 drug product Drugs 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95187907P | 2007-07-25 | 2007-07-25 | |
US95214007P | 2007-07-26 | 2007-07-26 | |
US97833007P | 2007-10-08 | 2007-10-08 | |
US98552607P | 2007-11-05 | 2007-11-05 | |
PCT/US2008/071191 WO2009015336A2 (en) | 2007-07-25 | 2008-07-25 | Controlled release interferon drug products and treatment of hcv infection using same |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0814363A2 true BRPI0814363A2 (pt) | 2015-01-27 |
Family
ID=40282165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0814363-3A2A BRPI0814363A2 (pt) | 2007-07-25 | 2008-07-25 | Produtos fármacos de interferon de liberação controlada e tratamento de infecção por hcv usando os mesmos |
Country Status (11)
Country | Link |
---|---|
US (1) | US8137661B2 (pt) |
EP (1) | EP2175865A4 (pt) |
JP (1) | JP2010534681A (pt) |
KR (1) | KR20100056479A (pt) |
CN (1) | CN101820887A (pt) |
AU (1) | AU2008279087A1 (pt) |
BR (1) | BRPI0814363A2 (pt) |
CA (1) | CA2694440A1 (pt) |
MX (1) | MX2010000965A (pt) |
WO (1) | WO2009015336A2 (pt) |
ZA (1) | ZA201000681B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI480272B (zh) * | 2008-10-09 | 2015-04-11 | Anadys Pharmaceuticals Inc | 藉由5,6-二氫-1h-吡啶-2-酮與一或多種其他抗病毒化合物的組合物抑制c型肝炎病毒的方法 |
RU2013127786A (ru) | 2010-11-19 | 2014-12-27 | Венус Ремедиз Лимитед | Новые конъюгаты для направленной доставки лекарственного средства |
ES2527510T1 (es) | 2011-10-21 | 2015-01-26 | Abbvie Inc. | Métodos para el tratamiento del VHC que comprenden al menos dos agentes antivirales de acción directa, ribavirina pero no interferón |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
DE112012003457T5 (de) | 2011-10-21 | 2015-03-12 | Abbvie Inc. | Kombinationsbehandlung (z.B. mit ABT-072 oder ABT-333 von DAAs zur Verwendung in der Behandlung von HCV) |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
US20140363396A1 (en) * | 2012-02-01 | 2014-12-11 | Kadmon Pharmaceuticals Llc | Once daily treatment of hepatitis c with ribavirin and taribavirin |
WO2013168179A2 (en) * | 2012-04-03 | 2013-11-14 | Rubicon Research Private Limited | Controlled release pharmaceutical formulations of antiviral agents |
WO2017189978A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6410697B1 (en) | 1979-04-20 | 2002-06-25 | Schering Corporation | Process for purifying human leukocyte interferon |
US6835557B1 (en) | 1980-01-08 | 2004-12-28 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides |
US6610830B1 (en) | 1980-07-01 | 2003-08-26 | Hoffman-La Roche Inc. | Microbial production of mature human leukocyte interferons |
US4749576A (en) | 1984-05-10 | 1988-06-07 | Ciba-Geigy Corporation | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
US6387365B1 (en) | 1995-05-19 | 2002-05-14 | Schering Corporation | Combination therapy for chronic hepatitis C infection |
WO1997016204A1 (en) | 1995-11-02 | 1997-05-09 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
US5980948A (en) | 1996-08-16 | 1999-11-09 | Osteotech, Inc. | Polyetherester copolymers as drug delivery matrices |
AU748756B2 (en) | 1997-07-18 | 2002-06-13 | Infimed Therapeutics, Inc. | Biodegradable macromers for the controlled release of biologically active substances |
US6172046B1 (en) | 1997-09-21 | 2001-01-09 | Schering Corporation | Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection |
DE69810822T2 (de) | 1997-09-21 | 2003-11-20 | Schering Corp | Kombinationstherapie zur Entfernung von nachweisbarer HCV-RNS in Patienten mit chronischer Hepatitis C-Infection |
US6472373B1 (en) | 1997-09-21 | 2002-10-29 | Schering Corporation | Combination therapy for eradicating detectable HCV-RNA in antiviral treatment naive patients having chronic hepatitis C infection |
ES2172288T3 (es) | 1998-05-15 | 2002-09-16 | Schering Corp | Terapia de combinacion que comprende ribavirina e interferon alfa en pacientes que no han sido sometidos a tratamiento antiviral y que tienen infeccion cronica de hepatitis c. |
US6194006B1 (en) | 1998-12-30 | 2001-02-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of microparticles having a selected release profile |
US20030206928A1 (en) | 1999-04-07 | 2003-11-06 | Pertti Tormala | Bioactive, bioabsorbable surgical polyethylene glycol and polybutylene terephtalate copolymer composites and devices |
US6465425B1 (en) | 2000-02-10 | 2002-10-15 | Alkermes Controlled Therapeutics, Inc. | Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins |
CN101676400A (zh) | 2000-07-31 | 2010-03-24 | 比洛克西治疗公司 | 在浮萍中表达生物活性多肽 |
US7959910B2 (en) | 2000-07-31 | 2011-06-14 | Biolex Therapeutics, Inc. | C-terminally truncated interferon alpha variants |
GB0018968D0 (en) | 2000-08-02 | 2000-09-20 | Pfizer Ltd | Particulate composition |
US7208167B2 (en) * | 2000-08-07 | 2007-04-24 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis C with thymosin and peptide combination therapy |
EP1443907A1 (en) | 2001-11-12 | 2004-08-11 | Alkermes Controlled Therapeutics, Inc. | Biocompatible polymer blends and uses thereof |
DK1587830T3 (da) | 2003-01-28 | 2009-10-26 | Academisch Ziekenhuis Leiden | Peptidinhibitorer af toksiner stammende fra LL-37 |
US20050269364A1 (en) | 2004-04-30 | 2005-12-08 | Gibson Rayce D | Inflatable seal for bin discharge system |
EP1621205A1 (en) | 2004-07-28 | 2006-02-01 | OctoPlus Technologies B.V. | Antimicrobial peptides derived from CAP18 |
EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
US20070021434A1 (en) * | 2005-06-24 | 2007-01-25 | Migenix Inc. | Non-nucleoside anti-hepacivirus agents and uses thereof |
CN101448497B (zh) * | 2006-01-09 | 2013-07-10 | 罗马克实验室有限公司 | 包含硝唑尼特、替唑尼特、或其混合物的组合物在制备治疗丙型肝炎药物中的应用 |
-
2008
- 2008-07-25 CA CA2694440A patent/CA2694440A1/en not_active Abandoned
- 2008-07-25 US US12/180,214 patent/US8137661B2/en not_active Expired - Fee Related
- 2008-07-25 KR KR1020107004036A patent/KR20100056479A/ko not_active Application Discontinuation
- 2008-07-25 MX MX2010000965A patent/MX2010000965A/es not_active Application Discontinuation
- 2008-07-25 BR BRPI0814363-3A2A patent/BRPI0814363A2/pt not_active IP Right Cessation
- 2008-07-25 WO PCT/US2008/071191 patent/WO2009015336A2/en active Application Filing
- 2008-07-25 EP EP08782397A patent/EP2175865A4/en not_active Withdrawn
- 2008-07-25 CN CN200880109654A patent/CN101820887A/zh active Pending
- 2008-07-25 JP JP2010518412A patent/JP2010534681A/ja active Pending
- 2008-07-25 AU AU2008279087A patent/AU2008279087A1/en not_active Abandoned
-
2010
- 2010-01-28 ZA ZA2010/00681A patent/ZA201000681B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2008279087A1 (en) | 2009-01-29 |
CA2694440A1 (en) | 2009-01-29 |
KR20100056479A (ko) | 2010-05-27 |
US20090068280A1 (en) | 2009-03-12 |
US8137661B2 (en) | 2012-03-20 |
WO2009015336A3 (en) | 2009-03-19 |
ZA201000681B (en) | 2013-07-31 |
CN101820887A (zh) | 2010-09-01 |
JP2010534681A (ja) | 2010-11-11 |
EP2175865A2 (en) | 2010-04-21 |
MX2010000965A (es) | 2010-03-09 |
WO2009015336A2 (en) | 2009-01-29 |
EP2175865A4 (en) | 2012-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |