BRPI0715396A2 - Vacinas de matriz proteíca e processos de produção e de administração de tais vacinas - Google Patents
Vacinas de matriz proteíca e processos de produção e de administração de tais vacinasInfo
- Publication number
- BRPI0715396A2 BRPI0715396A2 BRPI0715396-1A2A BRPI0715396A BRPI0715396A2 BR PI0715396 A2 BRPI0715396 A2 BR PI0715396A2 BR PI0715396 A BRPI0715396 A BR PI0715396A BR PI0715396 A2 BRPI0715396 A2 BR PI0715396A2
- Authority
- BR
- Brazil
- Prior art keywords
- vaccines
- production
- protein matrix
- administration processes
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0283—Shigella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/07—Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/116—Polyvalent bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
- A61K2039/645—Dendrimers; Multiple antigen peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83594406P | 2006-08-07 | 2006-08-07 | |
US60/835,944 | 2006-08-07 | ||
US93376407P | 2007-06-08 | 2007-06-08 | |
US60/933,764 | 2007-06-08 | ||
PCT/US2007/017528 WO2008021076A2 (en) | 2006-08-07 | 2007-08-07 | Protein matrix vaccines and methods of making and administering such vaccines |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0715396A2 true BRPI0715396A2 (pt) | 2013-11-26 |
BRPI0715396B1 BRPI0715396B1 (pt) | 2019-02-19 |
BRPI0715396B8 BRPI0715396B8 (pt) | 2021-05-25 |
Family
ID=39082551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0715396A BRPI0715396B8 (pt) | 2006-08-07 | 2007-08-07 | método de produção de uma composição para vacina |
Country Status (12)
Country | Link |
---|---|
US (3) | US8642042B2 (pt) |
EP (2) | EP3260134A1 (pt) |
JP (2) | JP5745221B2 (pt) |
KR (1) | KR101446238B1 (pt) |
AU (1) | AU2007284878B2 (pt) |
BR (1) | BRPI0715396B8 (pt) |
CA (1) | CA2660022C (pt) |
DK (1) | DK2056871T3 (pt) |
ES (1) | ES2658851T3 (pt) |
MX (1) | MX2009001412A (pt) |
TW (1) | TWI565713B (pt) |
WO (1) | WO2008021076A2 (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008021076A2 (en) * | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Protein matrix vaccines and methods of making and administering such vaccines |
US8524394B2 (en) * | 2007-11-22 | 2013-09-03 | Samsung Sdi Co., Ltd. | Negative electrode and negative active material for rechargeable lithium battery, and rechargeable lithium battery including same |
CA2730328C (en) | 2008-09-03 | 2015-03-31 | Board Of Trustees Of Michigan State University | Immunogenic escherichia coli heat stable enterotoxin |
US8647621B2 (en) | 2009-07-27 | 2014-02-11 | Fina Biosolutions, Llc | Method of producing protein-carbohydrate vaccines reduced in free carbohydrate |
EP2473188A4 (en) * | 2009-09-09 | 2014-01-01 | Matrivax Res & Dev Corp | PROTEIN MATRIX VACCINES WITH IMPROVED IMMUNOGENICITY |
US20110135689A1 (en) * | 2009-11-30 | 2011-06-09 | University Of Iowa Research Foundation | Vaccine, therapeutic composition and methods for treating or inhibiting francisella tularenis |
CA2836140C (en) | 2009-12-17 | 2016-06-21 | Fina Biosolutions, Llc | Chemical reagents for the activation of polysaccharides in the preparation of conjugate vaccines |
ES2743156T3 (es) | 2010-04-23 | 2020-02-18 | Serum Institute Of India Pvt Ltd | Método simple para eliminación simultánea de múltiples impurezas a partir de sobrenadantes de cultivo a niveles ultrabajos |
EP2566508B1 (en) * | 2010-05-03 | 2015-07-22 | Dcb-Usa Llc | Polysaccharide conjugation with detoxified e. coli heat labile enterotoxin (lt) used as vaccine |
CN103747798B (zh) * | 2011-05-18 | 2018-10-26 | 马特里瓦克斯公司 | 包含聚阳离子的蛋白质基质疫苗组合物 |
EP3628329B1 (en) | 2011-09-30 | 2022-08-10 | Dana-Farber Cancer Institute, Inc. | Therapeutic peptides comprising antibodies binding to mhc class 1 polypeptide related sequence a (mica) |
EP2946010B1 (en) | 2013-01-18 | 2018-08-29 | London School of Hygiene and Tropical Medicine | Glycosylation method |
GB201301085D0 (en) * | 2013-01-22 | 2013-03-06 | London School Hygiene & Tropical Medicine | Glycoconjugate Vaccine |
WO2014144791A2 (en) | 2013-03-15 | 2014-09-18 | Dana-Farber Cancer Institute, Inc. | Therapeutic peptides |
WO2015073831A1 (en) * | 2013-11-15 | 2015-05-21 | Liquidia Technologies, Inc. | Virtual conjugate particles |
MX371454B (es) | 2014-01-21 | 2020-01-29 | Pfizer | Polisacaridos capsulares de streptococcus pneumoniae y conjugados de los mismos. |
US20170198054A1 (en) * | 2014-05-21 | 2017-07-13 | Dana-Farber Cancer Institute | Methods for treating cancer with anti bip or anti mica antibodies |
US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
WO2018009906A1 (en) * | 2016-07-08 | 2018-01-11 | President And Fellows Of Harvard College | Whole cell-protein conjugates and methods of making the same |
SG11201901394XA (en) | 2016-09-02 | 2019-03-28 | Sanofi Pasteur Inc | Neisseria meningitidis vaccine |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
AU2018280272C1 (en) * | 2017-06-10 | 2021-05-06 | Inventprise, Inc. | Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
JP2020536968A (ja) | 2017-10-13 | 2020-12-17 | ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク | 共生疾患進行に対する包括的ワクチン設計 |
CA3084436A1 (en) | 2017-12-06 | 2019-07-18 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
CA3120922A1 (en) * | 2018-12-12 | 2020-06-18 | Pfizer Inc. | Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof |
AU2019401535B2 (en) | 2018-12-19 | 2023-12-14 | Merck Sharp & Dohme Llc | Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
CN114129719A (zh) * | 2021-12-03 | 2022-03-04 | 张公义 | 广谱疫苗的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4707543A (en) * | 1985-09-17 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines |
US4761470A (en) * | 1985-12-16 | 1988-08-02 | Merck & Co., Inc. | Immunogenic synthetic peptide capable of eliciting herpes simplex virus neutralizing antibody |
US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
CA2107106A1 (en) | 1991-03-28 | 1992-09-29 | Jo Klaveness | Cross-linking agent |
US5961970A (en) * | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
US5545669A (en) | 1994-06-02 | 1996-08-13 | Adams; Jerry L. | Anti-inflammatory compounds |
US5917017A (en) | 1994-06-08 | 1999-06-29 | President And Fellows Of Harvard College | Diphtheria toxin vaccines bearing a mutated R domain |
US5565204A (en) * | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
CA2232410C (en) * | 1995-09-18 | 2003-06-17 | United States Army Medical Research Materiel Command (Usamrmc) | Improved methods for the production of non-covalently complexed and multivalent proteosome sub-unit vaccines |
US6821331B2 (en) * | 2003-04-09 | 2004-11-23 | Wisconsin Alumni Research Foundation | Protein-polysaccharide hybrid hydrogels |
EP1522585A1 (en) * | 2003-10-09 | 2005-04-13 | Plant Research International B.V. | Chimeric carrier molecules for the production of mucosal vaccines |
WO2008021076A2 (en) * | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Protein matrix vaccines and methods of making and administering such vaccines |
-
2007
- 2007-08-07 WO PCT/US2007/017528 patent/WO2008021076A2/en active Application Filing
- 2007-08-07 AU AU2007284878A patent/AU2007284878B2/en active Active
- 2007-08-07 EP EP17168648.8A patent/EP3260134A1/en not_active Withdrawn
- 2007-08-07 EP EP07836580.6A patent/EP2056871B1/en active Active
- 2007-08-07 US US11/890,565 patent/US8642042B2/en active Active
- 2007-08-07 KR KR1020097004799A patent/KR101446238B1/ko active IP Right Grant
- 2007-08-07 DK DK07836580.6T patent/DK2056871T3/en active
- 2007-08-07 TW TW096128983A patent/TWI565713B/zh active
- 2007-08-07 BR BRPI0715396A patent/BRPI0715396B8/pt active IP Right Grant
- 2007-08-07 JP JP2009523818A patent/JP5745221B2/ja active Active
- 2007-08-07 ES ES07836580.6T patent/ES2658851T3/es active Active
- 2007-08-07 MX MX2009001412A patent/MX2009001412A/es active IP Right Grant
- 2007-08-07 CA CA2660022A patent/CA2660022C/en active Active
-
2013
- 2013-10-25 JP JP2013221989A patent/JP2014058530A/ja active Pending
- 2013-12-27 US US14/142,221 patent/US9216223B2/en active Active
-
2015
- 2015-11-24 US US14/950,113 patent/US9533032B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8642042B2 (en) | 2014-02-04 |
EP3260134A1 (en) | 2017-12-27 |
JP2010500354A (ja) | 2010-01-07 |
TW200823230A (en) | 2008-06-01 |
KR101446238B1 (ko) | 2014-10-01 |
US20140186399A1 (en) | 2014-07-03 |
US20160136257A1 (en) | 2016-05-19 |
EP2056871A2 (en) | 2009-05-13 |
US9216223B2 (en) | 2015-12-22 |
WO2008021076A3 (en) | 2008-12-04 |
BRPI0715396B8 (pt) | 2021-05-25 |
EP2056871A4 (en) | 2010-04-14 |
US9533032B2 (en) | 2017-01-03 |
DK2056871T3 (en) | 2018-02-26 |
JP5745221B2 (ja) | 2015-07-08 |
AU2007284878B2 (en) | 2013-01-17 |
TWI565713B (zh) | 2017-01-11 |
AU2007284878A1 (en) | 2008-02-21 |
EP2056871B1 (en) | 2017-11-15 |
CA2660022C (en) | 2014-11-04 |
US20080095803A1 (en) | 2008-04-24 |
WO2008021076A2 (en) | 2008-02-21 |
KR20090066272A (ko) | 2009-06-23 |
CA2660022A1 (en) | 2008-02-21 |
BRPI0715396B1 (pt) | 2019-02-19 |
JP2014058530A (ja) | 2014-04-03 |
MX2009001412A (es) | 2009-04-24 |
ES2658851T3 (es) | 2018-03-12 |
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/02/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/02/2019, OBSERVADAS AS CONDICOES LEGAIS |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/08/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |