BRPI0811142A8 - prevenção e tratamento de condições oculares associadas a complementos - Google Patents
prevenção e tratamento de condições oculares associadas a complementosInfo
- Publication number
- BRPI0811142A8 BRPI0811142A8 BRPI0811142A BRPI0811142A BRPI0811142A8 BR PI0811142 A8 BRPI0811142 A8 BR PI0811142A8 BR PI0811142 A BRPI0811142 A BR PI0811142A BR PI0811142 A BRPI0811142 A BR PI0811142A BR PI0811142 A8 BRPI0811142 A8 BR PI0811142A8
- Authority
- BR
- Brazil
- Prior art keywords
- eye conditions
- prevention
- treatment
- supplements
- conditions associated
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000013589 supplement Substances 0.000 title 1
- 230000000295 complement effect Effects 0.000 abstract 2
- 208000005590 Choroidal Neovascularization Diseases 0.000 abstract 1
- 206010060823 Choroidal neovascularisation Diseases 0.000 abstract 1
- 206010064930 age-related macular degeneration Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000002780 macular degeneration Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Cardiology (AREA)
- Wood Science & Technology (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93979107P | 2007-05-23 | 2007-05-23 | |
| PCT/US2008/064526 WO2008147883A1 (en) | 2007-05-23 | 2008-05-22 | Prevention and treatment of complement-associated eye conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0811142A2 BRPI0811142A2 (pt) | 2014-12-23 |
| BRPI0811142A8 true BRPI0811142A8 (pt) | 2018-12-18 |
Family
ID=39638868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0811142A BRPI0811142A8 (pt) | 2007-05-23 | 2008-05-22 | prevenção e tratamento de condições oculares associadas a complementos |
Country Status (28)
| Country | Link |
|---|---|
| US (6) | US8007791B2 (Direct) |
| EP (1) | EP2152755B1 (Direct) |
| JP (4) | JP5416695B2 (Direct) |
| KR (1) | KR101540126B1 (Direct) |
| CN (3) | CN101754980B (Direct) |
| AR (1) | AR066660A1 (Direct) |
| AU (1) | AU2008256835B2 (Direct) |
| BR (1) | BRPI0811142A8 (Direct) |
| CA (1) | CA2683498A1 (Direct) |
| CL (1) | CL2008001498A1 (Direct) |
| CY (1) | CY1116062T1 (Direct) |
| DK (1) | DK2152755T3 (Direct) |
| ES (1) | ES2533242T3 (Direct) |
| HK (1) | HK1207327A1 (Direct) |
| HR (1) | HRP20150281T1 (Direct) |
| IL (2) | IL201476A (Direct) |
| MX (1) | MX2009012422A (Direct) |
| PE (1) | PE20090294A1 (Direct) |
| PH (1) | PH12013500992B1 (Direct) |
| PL (1) | PL2152755T3 (Direct) |
| PT (1) | PT2152755E (Direct) |
| RS (1) | RS53901B1 (Direct) |
| RU (2) | RU2522976C2 (Direct) |
| SG (1) | SG10201401404RA (Direct) |
| SI (1) | SI2152755T1 (Direct) |
| TW (2) | TWI419704B (Direct) |
| WO (1) | WO2008147883A1 (Direct) |
| ZA (1) | ZA200907028B (Direct) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001261103B2 (en) * | 2000-04-29 | 2007-08-23 | University Of Iowa Research Foundation | Diagnostics and therapeutics for macular degeneration-related disorders |
| NZ594285A (en) * | 2005-11-04 | 2013-02-22 | Genentech Inc | USE OF COMPLEMENT PATHWAY INHIBITOR ANTIBODY AGAINST C5a TO TREAT OCULAR DISEASES |
| CL2007003161A1 (es) | 2006-11-02 | 2008-05-30 | Genentech Inc | Anticuerpos anti-factor d; acidos nucleicos que los codifican; vector y linea celular que los comprenden; metodo de produccion; composicion farmaceutica que comprende a los anticuerpos; y su uso para tratar trastornos mediados por el complemento como |
| AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| US8735424B2 (en) * | 2008-09-02 | 2014-05-27 | Novartis Ag | Bicyclic kinase inhibitors |
| PL2391419T3 (pl) | 2009-01-29 | 2019-12-31 | Forsight Vision4, Inc. | Dostarczanie leku do tylnego odcinka |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| US9309325B2 (en) | 2009-05-07 | 2016-04-12 | The Regents Of The University Of California | Antibodies and methods of use thereof |
| US20110165648A1 (en) * | 2009-11-04 | 2011-07-07 | Menno Van Lookeren Campagne | Co-crystal structure of factor D and anti-factor D antibody |
| CN103209664A (zh) | 2010-08-05 | 2013-07-17 | 弗赛特影像4股份有限公司 | 可植入的治疗装置 |
| PL2635704T3 (pl) | 2010-11-01 | 2017-09-29 | F.Hoffmann-La Roche Ag | Przewidywanie progresji do zaawansowanego zwyrodnienia plamki żółtej związanego z wiekiem z zastosowaniem wskaźnika poligenicznego |
| PH12013501436A1 (en) | 2011-01-04 | 2013-09-09 | Novartis Ag | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd) |
| US9540443B2 (en) | 2011-01-26 | 2017-01-10 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies |
| JP6154897B2 (ja) | 2012-06-28 | 2017-06-28 | ノバルティス アーゲー | ピロリジン誘導体、および補体経路調節因子としてのその使用 |
| US9388199B2 (en) | 2012-06-28 | 2016-07-12 | Novartis Ag | Pyrrolidine derivatives and their use as complement pathway modulators |
| ES2710491T3 (es) | 2012-06-28 | 2019-04-25 | Novartis Ag | Moduladores de la vía del complemento y sus usos |
| ES2647124T3 (es) | 2012-06-28 | 2017-12-19 | Novartis Ag | Derivados de pirrolidina y su uso como moduladores de la ruta del complemento |
| US9487483B2 (en) | 2012-06-28 | 2016-11-08 | Novartis Ag | Complement pathway modulators and uses thereof |
| JP6238980B2 (ja) | 2012-07-12 | 2017-11-29 | ノバルティス アーゲー | 補体経路モジュレーターおよびその使用 |
| NZ731881A (en) | 2012-07-25 | 2022-07-29 | Celldex Therapeutics Inc | Anti-kit antibodies and uses thereof |
| US9255155B2 (en) | 2013-01-31 | 2016-02-09 | The Regents Of The University Of California | Antibodies specific for urokinase-type plasminogen activator and methods of treating cancer |
| WO2014160884A1 (en) | 2013-03-28 | 2014-10-02 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| JP6463359B2 (ja) | 2013-08-12 | 2019-01-30 | ジェネンテック, インコーポレイテッド | 補体関連病態を治療するための組成物及び方法 |
| WO2015054298A1 (en) * | 2013-10-07 | 2015-04-16 | Massachusetts Eye And Ear Infirmary | Methods of preventing or reducing photoreceptor cell death |
| CA2928702A1 (en) * | 2013-10-25 | 2015-04-30 | Children's Medical Center Corporation | Methods of treating or preventing vascular diseases of the retina |
| MX2016014160A (es) * | 2014-05-01 | 2017-02-16 | Genentech Inc | Variantes del anticuerpo anti-factor d y sus usos. |
| WO2015179737A2 (en) | 2014-05-23 | 2015-11-26 | Kolltan Pharmaceuticals, Inc. | Treatment of eosinophil or mast cell related disorders |
| ES3032775T3 (en) * | 2015-09-23 | 2025-07-24 | Sangamo Therapeutics Inc | Htt repressors and uses thereof |
| EP3368090A1 (en) * | 2015-10-30 | 2018-09-05 | H. Hoffnabb-La Roche Ag | Anti-factor d antibody variant conjugates and uses thereof |
| EP3666901A1 (en) | 2015-10-30 | 2020-06-17 | F. Hoffmann-La Roche AG | Methods of measuring factor d activity and potency of factor d inhibitors |
| WO2017075212A1 (en) | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-htra1 antibodies and methods of use thereof |
| EP3368074A2 (en) | 2015-10-30 | 2018-09-05 | Hoffmann-La Roche AG | Anti-factor d antibodies and conjugates |
| CN108699121B (zh) | 2015-12-23 | 2023-07-04 | 艾丽法有限责任公司 | 用于抑制补体激活的多肽 |
| WO2017127761A1 (en) | 2016-01-20 | 2017-07-27 | Vitrisa Therapeutics, Inc. | Compositions and methods for inhibiting factor d |
| WO2018136827A1 (en) | 2017-01-20 | 2018-07-26 | Vitrisa Therapeutics, Inc. | Stem-loop compositions and methods for inhibiting factor d |
| EP3580241A4 (en) | 2017-02-10 | 2021-01-06 | The Trustees Of The University Of Pennsylvania | ANTIFACTOR D ANTIBODIES AND USES THEREOF |
| CN109632924B (zh) * | 2018-12-17 | 2022-02-08 | 上海市第一人民医院 | 人黄斑新生血管性疾病的血浆脂质标记物及其应用 |
| WO2021009778A2 (en) * | 2019-07-18 | 2021-01-21 | Pandorum Technologies Private Limited | Methods for culturing mesenchymal stem cells, products thereof, and applications thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6620915B2 (en) * | 1993-12-23 | 2003-09-16 | Icos Corporation | Monoclonal antibodies specific for integrin α-d subunit |
| WO2001004311A1 (en) | 1999-07-07 | 2001-01-18 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20050197285A1 (en) * | 1997-03-07 | 2005-09-08 | Rosen Craig A. | Human secreted proteins |
| US6472520B2 (en) * | 1997-03-21 | 2002-10-29 | The Trustees Of Columbia University In The City Of New York | Rat PEG-3 promoter |
| US6410708B1 (en) * | 1997-11-21 | 2002-06-25 | Genentech, Inc. | Nucleic acids encoding A-33 related antigen polypeptides |
| US7282565B2 (en) * | 1998-03-20 | 2007-10-16 | Genentech, Inc. | PRO362 polypeptides |
| US8088386B2 (en) * | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
| US8007798B2 (en) * | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7192589B2 (en) * | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
| US7419663B2 (en) * | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| CA2309358A1 (en) | 1997-11-21 | 1999-06-03 | Genentech, Inc. | A-33 related antigens and their pharmacological uses |
| EP1053245A4 (en) * | 1998-02-09 | 2002-04-17 | Human Genome Sciences Inc | 45 HUMAN SECRETED PROTEINS |
| US6956107B2 (en) | 1998-02-20 | 2005-10-18 | Tanox, Inc. | Inhibitors of complement activation |
| NZ506920A (en) * | 1998-02-20 | 2003-12-19 | Tanox Inc | Inhibitors of complement activation |
| NZ507435A (en) | 1998-03-10 | 2003-12-19 | Genentech Inc | Novel polypeptides and nucleic acids with homology to cornichon |
| CA2340794A1 (en) | 1998-08-27 | 2000-03-09 | Incyte Pharmaceuticals, Inc. | Protein transport-associated molecules |
| KR100468978B1 (ko) | 1998-12-16 | 2005-02-02 | 제넨테크, 인크. | 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 |
| KR20010081089A (ko) * | 1998-12-21 | 2001-08-25 | 에드워드 에이. 맥더모 2세, 로이드 제이. 오울드 | 절단된 vegf-d에 대한 항체 및 그것의 이용 |
| DE69935085T2 (de) | 1998-12-22 | 2007-08-23 | Genentech, Inc., South San Francisco | Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums |
| EP1220905A2 (en) | 1999-03-08 | 2002-07-10 | Genentech Inc. | Composition and methods for the treatment of immune related diseases |
| JP4836329B2 (ja) | 1999-03-11 | 2011-12-14 | メルク セローノ エス.エイ. | 血管接着分子およびその機能の調節 |
| US6642353B1 (en) * | 1999-03-17 | 2003-11-04 | Chugai Seiyaku Kabushiki Kaisha | Peptide ligands for the erythropoietin receptor |
| AU1423601A (en) | 1999-11-02 | 2001-05-30 | Uliyanovsky Gosudarstvenny Tekhnichesky Universitet | Method for cleaning liquids of ferromagnetic particles and device for the implementation thereof |
| JP2003514541A (ja) | 1999-11-19 | 2003-04-22 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 18個のヒト分泌タンパク質 |
| EP1690872A3 (en) | 1999-12-01 | 2006-08-23 | Genentech, Inc. | Composition and methods for the diagnosis of tumours |
| CA2412211A1 (en) | 2000-06-23 | 2002-01-03 | Genetech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| AU2001271973A1 (en) | 2000-07-20 | 2002-02-05 | Kevin P. Baker | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| US20040152105A1 (en) * | 2002-09-06 | 2004-08-05 | Cytos Biotechnology Ag. | Immune modulatory compounds and methods |
| RU2232991C1 (ru) * | 2003-04-09 | 2004-07-20 | Государственное учреждение "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" | Способ определения функциональной активности фактора d комплемента человека |
| WO2006071856A2 (en) | 2004-12-23 | 2006-07-06 | Glycofi, Inc. | Immunoglobulins comprising predominantly a man5glcnac2 glycoform |
| NZ594285A (en) * | 2005-11-04 | 2013-02-22 | Genentech Inc | USE OF COMPLEMENT PATHWAY INHIBITOR ANTIBODY AGAINST C5a TO TREAT OCULAR DISEASES |
| US20070190057A1 (en) | 2006-01-23 | 2007-08-16 | Jian Wu | Methods for modulating mannose content of recombinant proteins |
| CL2007003161A1 (es) * | 2006-11-02 | 2008-05-30 | Genentech Inc | Anticuerpos anti-factor d; acidos nucleicos que los codifican; vector y linea celular que los comprenden; metodo de produccion; composicion farmaceutica que comprende a los anticuerpos; y su uso para tratar trastornos mediados por el complemento como |
| AR066660A1 (es) * | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| JP4349447B2 (ja) | 2007-07-19 | 2009-10-21 | トヨタ自動車株式会社 | インバータ制御装置および車両 |
-
2008
- 2008-05-21 AR ARP080102150A patent/AR066660A1/es unknown
- 2008-05-22 JP JP2010509554A patent/JP5416695B2/ja not_active Expired - Fee Related
- 2008-05-22 EP EP08756130.4A patent/EP2152755B1/en active Active
- 2008-05-22 KR KR1020097026746A patent/KR101540126B1/ko not_active Expired - Fee Related
- 2008-05-22 CA CA002683498A patent/CA2683498A1/en not_active Abandoned
- 2008-05-22 RS RS20150223A patent/RS53901B1/sr unknown
- 2008-05-22 CN CN200880100137.7A patent/CN101754980B/zh not_active Expired - Fee Related
- 2008-05-22 MX MX2009012422A patent/MX2009012422A/es active IP Right Grant
- 2008-05-22 CN CN201410486706.3A patent/CN104367999A/zh active Pending
- 2008-05-22 AU AU2008256835A patent/AU2008256835B2/en not_active Ceased
- 2008-05-22 SI SI200831405T patent/SI2152755T1/sl unknown
- 2008-05-22 US US12/154,466 patent/US8007791B2/en not_active Expired - Fee Related
- 2008-05-22 PT PT87561304T patent/PT2152755E/pt unknown
- 2008-05-22 RU RU2009147744/10A patent/RU2522976C2/ru not_active IP Right Cessation
- 2008-05-22 ES ES08756130.4T patent/ES2533242T3/es active Active
- 2008-05-22 DK DK08756130.4T patent/DK2152755T3/en active
- 2008-05-22 SG SG10201401404RA patent/SG10201401404RA/en unknown
- 2008-05-22 BR BRPI0811142A patent/BRPI0811142A8/pt not_active Application Discontinuation
- 2008-05-22 HR HRP20150281AT patent/HRP20150281T1/hr unknown
- 2008-05-22 WO PCT/US2008/064526 patent/WO2008147883A1/en not_active Ceased
- 2008-05-22 PL PL08756130T patent/PL2152755T3/pl unknown
- 2008-05-22 CN CN201610972614.5A patent/CN107096029B/zh not_active Expired - Fee Related
- 2008-05-23 TW TW097119194A patent/TWI419704B/zh not_active IP Right Cessation
- 2008-05-23 PE PE2008000887A patent/PE20090294A1/es not_active Application Discontinuation
- 2008-05-23 CL CL2008001498A patent/CL2008001498A1/es unknown
- 2008-05-23 TW TW102134844A patent/TW201417829A/zh unknown
-
2009
- 2009-10-08 ZA ZA2009/07028A patent/ZA200907028B/en unknown
- 2009-10-13 IL IL201476A patent/IL201476A/en active IP Right Grant
-
2011
- 2011-07-22 US US13/189,301 patent/US8268310B2/en not_active Expired - Fee Related
-
2012
- 2012-07-20 US US13/554,787 patent/US8497094B2/en not_active Expired - Fee Related
-
2013
- 2013-05-16 PH PH12013500992A patent/PH12013500992B1/en unknown
- 2013-06-27 US US13/929,167 patent/US20130302333A1/en not_active Abandoned
- 2013-11-15 JP JP2013236445A patent/JP2014087346A/ja not_active Withdrawn
-
2014
- 2014-04-03 RU RU2014113046/10A patent/RU2014113046A/ru not_active Application Discontinuation
-
2015
- 2015-02-27 CY CY20151100205T patent/CY1116062T1/el unknown
- 2015-08-14 HK HK15107851.6A patent/HK1207327A1/xx unknown
-
2016
- 2016-01-29 JP JP2016015288A patent/JP2016145205A/ja not_active Withdrawn
- 2016-02-03 US US15/014,886 patent/US20160272726A1/en not_active Abandoned
- 2016-10-27 IL IL248552A patent/IL248552A0/en unknown
-
2017
- 2017-07-28 JP JP2017146477A patent/JP2017197577A/ja active Pending
- 2017-11-29 US US15/826,016 patent/US20180079826A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0811142A8 (pt) | prevenção e tratamento de condições oculares associadas a complementos | |
| CL2017001191A1 (es) | Compuestos derivados de carbamoilpiridona policíclicos; composición farmacéutica que los comprende; y su uso para el tratamiento de una infección de vih en un humano que tiene o se encuentra en riesgo de tener la infección. | |
| EA201590053A1 (ru) | Модуляторы пути системы комплемента и их применение | |
| DOP2014000008A (es) | 4-imidazopiridazina-1-il-benzamidas y 4-imidazotriazina-1-il-benzamidas como inhibidores de btk | |
| CL2008003120A1 (es) | Compuestos derivados de fenilalquil-, fenilalquenil-, fenilalquinil- amina, feniltioalquilamina, fenilaminoalquilamina, fenilalcoxiamina y fenilalquilguanidina; composicion farmaceutica; y uso de los compuestos para tratar un trastorno o enfermedad oftalmologica tal como retinopatia, maculopatia, retinitis pigmentosa, uveitis, entre otras. | |
| MX2013008851A (es) | Composiciones y metodos para el tratamiento de inflamacion cronica y enfermedades inflamatorias. | |
| CL2014000171A1 (es) | Compuestos derivados de tetrahidropirido-piridina y tetrahidropirido-pirimidina, moduladores de receptores de c5a; composicion farmaceutica que los comprende; combinacion farmaceutica; uso en el tratamiento de degeneracion macular relacionada con la edad, retinopatia diabetica, esclerosis multiple, ave, enfermedad de parkinson, enfermedad de crohn, entre otras. | |
| UY36465A (es) | Compuestos policíclicos de carbamoilpiridona y su uso farmacéutico | |
| UY32673A (es) | Nuevas pirimidinas, composiciones farmaceuticas que las contienen, procedimientos de preparaciones y su aplicacion como medicamentos | |
| MX377410B (es) | Antagonistas de receptores de integrina y sus metodos de uso. | |
| UA113165C2 (xx) | Застосування комбінації баклофену і акампросату для лікування неврологічних захворювань та композиція, яка містить баклофен і акампросат | |
| MX2013007867A (es) | Compuestos de indol o analogos de los mismos utiles para el mismo tratamiento de degeneracion macular relacionada con la edad (amd). | |
| MX2016015248A (es) | Compuestos imidazo[1,2-a]pirazin-1-il-benzamida para tratar atrofia muscular espinal. | |
| BR112013030554A2 (pt) | forma cristalina de ciclosporina a, métodos de preparação e métodos para uso da mesma | |
| BR112014015568A2 (pt) | compostos carbamato de fenila para uso em prevenção ou tratamento de epilepsia | |
| ECSP11010956A (es) | Compuestos enlazados con azufre para el tratamiento de enfermedades y trastornos oftalmicos | |
| GT201400059A (es) | Derivados de estra-1,3,5(10),16-tetraen-3-carboxamida, proceidmientos para su preparación, preparados farmacéuticos que los contienen, así como su uso para la preparacion de medicamentos | |
| ECSP17026748A (es) | Diamino-quinoleína 2,4 sustituida como nuevos agentes anticancerígenos | |
| ES2524385R1 (es) | Composición farmacéutica y su uso para preparar un medicamento destinado al tratamiento y la prevención de enfermedades causadas por el VIH | |
| MX2016000294A (es) | Composicion farmaceutica para liberacion sostenida de lanreotida. | |
| BRPI0820343A2 (pt) | Anticorpos de antifator b e seus usos | |
| EA201591415A1 (ru) | Фармацевтические композиции, включающие многокомпонентные кристаллические частицы, подходящие для применения в ингаляционной терапии | |
| BR112014026817A2 (pt) | derivados do pantotenato para o tratamento de transtornos neurológicos | |
| AR079000A1 (es) | Terapia anticancerosa dirigida a celulas madre cancerosas resistentes a las drogas | |
| AR054442A1 (es) | Formas de dosificacion, composiciones farmaceuticas y metodos para el suministro sub-tenon |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |