MX377410B - Antagonistas de receptores de integrina y sus metodos de uso. - Google Patents

Antagonistas de receptores de integrina y sus metodos de uso.

Info

Publication number
MX377410B
MX377410B MX2013012953A MX2013012953A MX377410B MX 377410 B MX377410 B MX 377410B MX 2013012953 A MX2013012953 A MX 2013012953A MX 2013012953 A MX2013012953 A MX 2013012953A MX 377410 B MX377410 B MX 377410B
Authority
MX
Mexico
Prior art keywords
methods
receptor antagonists
integrin receptor
glycinyl
integrin
Prior art date
Application number
MX2013012953A
Other languages
English (en)
Other versions
MX2013012953A (es
Inventor
Hampar L Karageozian
John Y Park
Michael John Mackel
Vicken H Karageozian
Original Assignee
Allegro Pharmaceuticals Inc Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allegro Pharmaceuticals Inc Star filed Critical Allegro Pharmaceuticals Inc Star
Publication of MX2013012953A publication Critical patent/MX2013012953A/es
Publication of MX377410B publication Critical patent/MX377410B/es

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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • G—PHYSICS
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)

Abstract

La presente invención se refiere a el uso de una cantidad efectiva de una composición farmacéutica que comprende un péptido que inhibe integrina, que comprende Glicinil-Arginil-Glicinil-ÁcidoCisteíco-Treonil-Prolina-COOH o una sal farmacéuticamente aceptable del mismo, en la preparación de un medicamento útil para el tratamiento de edema macular.
MX2013012953A 2011-05-09 2012-05-09 Antagonistas de receptores de integrina y sus metodos de uso. MX377410B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161484194P 2011-05-09 2011-05-09
US201161486195P 2011-05-13 2011-05-13
US201261643118P 2012-05-04 2012-05-04
PCT/US2012/037177 WO2012154894A2 (en) 2011-05-09 2012-05-09 Integrin receptor antagonists and their methods of use

Publications (2)

Publication Number Publication Date
MX2013012953A MX2013012953A (es) 2016-09-09
MX377410B true MX377410B (es) 2025-03-10

Family

ID=47139985

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013012953A MX377410B (es) 2011-05-09 2012-05-09 Antagonistas de receptores de integrina y sus metodos de uso.

Country Status (14)

Country Link
US (2) US9896480B2 (es)
EP (2) EP2707036A4 (es)
JP (4) JP6106159B2 (es)
KR (2) KR102165421B1 (es)
CN (1) CN104080467B (es)
AU (5) AU2012253511A1 (es)
BR (1) BR112013028914B1 (es)
CA (1) CA2835214C (es)
ES (1) ES2820855T3 (es)
IL (1) IL229299A0 (es)
MX (1) MX377410B (es)
RU (1) RU2721907C2 (es)
WO (1) WO2012154894A2 (es)
ZA (1) ZA201308325B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11673914B2 (en) 2009-11-10 2023-06-13 Allegro Pharmaceuticals, LLC Peptide therapies for reduction of macular thickening
NZ599899A (en) 2009-11-10 2014-10-31 Allegro Pharmaceuticals Inc Compositions and methods for inhibiting cellular adhesion or directing diagnostic or therapeutic agents to rgd binding sites
EP2707036A4 (en) * 2011-05-09 2015-03-18 Allegro Pharmaceuticals Inc INTEGRIN RECEPTOR ANTAGONISTS AND METHOD FOR THEIR USE
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