BRPI0809942B8 - processos de preparação de porfirinas, pirrometanos e compostos intermediários - Google Patents

processos de preparação de porfirinas, pirrometanos e compostos intermediários

Info

Publication number
BRPI0809942B8
BRPI0809942B8 BRPI0809942A BRPI0809942A BRPI0809942B8 BR PI0809942 B8 BRPI0809942 B8 BR PI0809942B8 BR PI0809942 A BRPI0809942 A BR PI0809942A BR PI0809942 A BRPI0809942 A BR PI0809942A BR PI0809942 B8 BRPI0809942 B8 BR PI0809942B8
Authority
BR
Brazil
Prior art keywords
porphyrins
preparation
pyrromethanes
processes
formula
Prior art date
Application number
BRPI0809942A
Other languages
English (en)
Inventor
Boudier Andreas
Flubacher Dietmar
Spiel Vogel Dirk
Müller Markus
Martin Pierre
Original Assignee
Sanofi Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur filed Critical Sanofi Pasteur
Publication of BRPI0809942A2 publication Critical patent/BRPI0809942A2/pt
Publication of BRPI0809942B1 publication Critical patent/BRPI0809942B1/pt
Publication of BRPI0809942B8 publication Critical patent/BRPI0809942B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

processos de preparação de porfirinas, porfirinas e pirrometanos. a presente invenção refere-se a um processo de preparação de uma porfirina de fórmula (i) eventualmente sob a forma de um sal com um metal alcalino e/ou sob a forma de um complexo metálico, na qual: r e r' são tais como definidos na reivindicações 1, compreendendo uma etapa de condensação, em meio ácido, entre um dipirrometano de fórmula (ii) na qual r'b é tal como definido anteriormente para (i), e um dipirrometano de fómula (iii) na qual r'' é tal como definido na reivindicação 1, assim como os compostos de fórmula (iii)
BRPI0809942A 2007-03-30 2008-03-31 processos de preparação de porfirinas, pirrometanos e compostos intermediários BRPI0809942B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR07/02334 2007-03-30
FR0702334A FR2914302A1 (fr) 2007-03-30 2007-03-30 Procede de preparation de derives de porphyrine, telle que la protoporphyrine (ix) et intermediaire de synthese
PCT/FR2008/000440 WO2008142250A2 (fr) 2007-03-30 2008-03-31 Procede de preparation de derives de porphyrine, telle que la protoporphyrine (ix) et intermediaire de synthese

Publications (3)

Publication Number Publication Date
BRPI0809942A2 BRPI0809942A2 (pt) 2014-10-07
BRPI0809942B1 BRPI0809942B1 (pt) 2020-09-24
BRPI0809942B8 true BRPI0809942B8 (pt) 2021-05-25

Family

ID=38722680

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809942A BRPI0809942B8 (pt) 2007-03-30 2008-03-31 processos de preparação de porfirinas, pirrometanos e compostos intermediários

Country Status (15)

Country Link
US (2) US8026358B2 (pt)
EP (1) EP2142501B1 (pt)
JP (1) JP5427169B2 (pt)
KR (1) KR101496216B1 (pt)
CN (2) CN103641763A (pt)
AR (1) AR065873A1 (pt)
AU (1) AU2008252764B2 (pt)
BR (1) BRPI0809942B8 (pt)
CA (1) CA2680264C (pt)
FR (1) FR2914302A1 (pt)
IL (1) IL200214A (pt)
MX (1) MX2009008802A (pt)
TW (1) TWI428341B (pt)
WO (1) WO2008142250A2 (pt)
ZA (1) ZA200905953B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104116745B (zh) 2006-10-04 2018-07-06 婴儿护理药品公司 包含锡泊芬的组合物
EP2691398B1 (en) 2011-03-30 2016-09-28 InfaCare Pharmaceutical Corporation Methods for synthesizing metal mesoporphyrins
CN102697182B (zh) * 2012-06-15 2014-07-30 川渝中烟工业有限责任公司 一种降低卷烟烟气中氨的滤嘴添加剂制备方法及应用
FR2992656B1 (fr) * 2012-07-02 2016-10-07 Sanofi Pasteur Procede de production d'antigenes haemophilus influenzae type b
KR101894575B1 (ko) * 2017-01-03 2018-09-04 주식회사 인트론바이오테크놀로지 돼지 피로부터 유래되지 않은 헴철을 제조할 수 있는 화학적 방법
KR102429286B1 (ko) * 2017-01-03 2022-08-04 주식회사 인트론바이오테크놀로지 돼지 피로부터 유래되지 않은 헴철을 제조할 수 있는 생물학적 방법
KR20180079846A (ko) * 2017-01-03 2018-07-11 주식회사 인트론바이오테크놀로지 돼지 피로부터 유래되지 않은 헴철을 제조할 수 있는 생물학적 방법
CN108822144B (zh) * 2018-08-16 2020-01-21 湖南师范大学 氟硼扩环卟啉化合物、芳香性或反芳香性扩环卟啉化合物及合成方法
CN114790161B (zh) * 2022-05-16 2023-12-01 百顺药业有限公司 4-甲氧基羰基乙基-3-甲基-2-吡咯醛的合成方法及其中间体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
JPS61186385A (ja) * 1985-02-13 1986-08-20 Sato Yakugaku Kenkyusho:Kk デユウテロポルフイリン誘導体及びその塩
JPH01203385A (ja) * 1988-02-08 1989-08-16 Tosoh Corp プロトポルフィリンジエステルの製造方法
US5659029A (en) * 1995-12-22 1997-08-19 Sun Company, Inc. (R&M) Preparation of porphyrins and their metal complexes
CA2283057A1 (en) * 1997-02-05 1998-08-06 Board Of Regents, The University Of Texas System Porphyrin compounds as telomerase inhibitors
EP1145713A4 (en) * 1999-01-12 2003-08-06 Kyowa Hakko Kogyo Kk Telomerase inhibitors
US6827926B2 (en) * 2001-05-31 2004-12-07 Miravant Pharmaceuticals, Inc. Metallotetrapyrrolic photosensitizing agents for use in photodynamic therapy
CN1418880A (zh) * 2001-11-14 2003-05-21 上海金赤生物制品有限公司 一种原卟啉二钠盐的制备方法
CN1193034C (zh) * 2001-11-14 2005-03-16 上海金赤生物制品有限公司 一种铁卟啉钠盐的制备方法
CN1238355C (zh) * 2003-11-21 2006-01-25 湖南大学 一种金属卟啉的合成方法
EP1773819A4 (en) * 2004-07-15 2009-05-06 Univ Sydney PORPHYRENE-BONDED METRONIDAZOLE AGAINST DENTISTRY PORPHYROMONAS GINGIVALIS

Also Published As

Publication number Publication date
KR101496216B1 (ko) 2015-02-26
US8026358B2 (en) 2011-09-27
CN101657420B (zh) 2013-12-18
TW200902536A (en) 2009-01-16
AR065873A1 (es) 2009-07-08
IL200214A0 (en) 2010-04-29
WO2008142250A3 (fr) 2009-04-16
JP2010523532A (ja) 2010-07-15
MX2009008802A (es) 2009-08-25
US8420805B2 (en) 2013-04-16
TWI428341B (zh) 2014-03-01
IL200214A (en) 2015-06-30
CA2680264A1 (en) 2008-11-27
AU2008252764B2 (en) 2013-10-31
KR20090127139A (ko) 2009-12-09
FR2914302A1 (fr) 2008-10-03
EP2142501A2 (fr) 2010-01-13
ZA200905953B (en) 2010-11-24
WO2008142250A2 (fr) 2008-11-27
EP2142501B1 (fr) 2014-10-08
BRPI0809942A2 (pt) 2014-10-07
US20080242857A1 (en) 2008-10-02
US20110306761A1 (en) 2011-12-15
BRPI0809942B1 (pt) 2020-09-24
CN103641763A (zh) 2014-03-19
AU2008252764A1 (en) 2008-11-27
CA2680264C (en) 2016-08-16
JP5427169B2 (ja) 2014-02-26
CN101657420A (zh) 2010-02-24

Similar Documents

Publication Publication Date Title
BRPI0809942B8 (pt) processos de preparação de porfirinas, pirrometanos e compostos intermediários
MY150542A (en) Cmet inhibitors
RS53574B1 (en) PYROLOPYRIMIDINE COMPOUNDS AS CDK INHIBITORS
DK3106463T6 (da) Pyrazolo[1,5-]pyrimidinforbindelse som trk-kinasehæmmer
CL2008003684A1 (es) Composicion farmaceutica que comprende una sal de aluminio, que tiene una relacion molar de aluminio a cloruro de 0,3:1 a 3:1 aproximadamente, ademas comprende zirconio; metodo de preparacion de la composicion; uso como antitranspirante.
NO20074093L (no) Fremgangsmater for fremstilling av glukopyranosyl-substituerte benzyl-benzenderivater og mellomprodukter derav
NO20080129L (no) Fremgangsmate for fremstilling av dihydrokinazoliner
BRPI0822106A2 (pt) "processo para preparação de ácido metacrílico de alta pureza."
BR112015021240A2 (pt) processo para sal de sódio de (2s, 5r)-2-carboxamido-7-oxo-6-sulfo-oxi-1,6-diaza-biciclo[3.2.1]octano
MY152283A (en) Polo-like kinase inhibitirs
EA201190205A1 (ru) ПОЛЕЗНЫЕ ФАРМАЦЕВТИЧЕСКИЕ СОЛИ 7-[(3R,4R)-3-ГИДРОКСИ-4-ГИДРОКСИМЕТИЛПИРРОЛИДИН-1-ИЛМЕТИЛ]-3,5-ДИГИДРОПИРРОЛО[3,2-d]ПИРИМИДИН-4-ОНА
AR110128A2 (es) Compuesto del grupo de las 3-(imidazoil)-pirazolo[3,4-b]piridinas, composición farmacéutica que lo comprende y método para preparar el mismo
HN2009001262A (es) Derivados de imidazol como inhibidores de proteina de huso de cinesina (eg-5)
ITMI20050247A1 (it) Processo per la preparazione di montelukast
BR112015001769A2 (pt) Processo para a síntese de compostos de ureia substituída
NO20081207L (no) Isoquinolines as IGF-1R inhibitors
DE502006004524D1 (de) Verfahren zur herstellung von 3,7-diaza-bicycloä3.3.1ünonan-verbindungen
EA201100350A1 (ru) Противогрибковые средства
DE602006014001D1 (de) Herstellung von 2-aminothiazol-5-carbonsäurederivaten
DE502006003030D1 (de) Verwendung von inhibitoren des na+/h+ austauschers, subtyp 5 (nhe5) zur gedächtnisverbesserung
BR112015021393A2 (pt) processo para a preparação de (2s,5r)-7-oxo-6-sulfoóxi-2-[(((3r)-piperidina-3-carbonil)-hidrazina carbonil]-1,6-diaza-biciclo[3.2.1]- octano
BRPI0907052B8 (pt) processo para a preparação de compostos
IT1391108B1 (it) Processo per la preparazione di etilidennorbornene.
BRPI0912365A2 (pt) processo para a preparação de 1,2-propanodiol por hidrogenólise de glicerina
MD4009C2 (ro) Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/09/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/03/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF