WO2008075380A3 - Process for the preparation of thiazolidine derivatives - Google Patents

Process for the preparation of thiazolidine derivatives Download PDF

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Publication number
WO2008075380A3
WO2008075380A3 PCT/IN2007/000599 IN2007000599W WO2008075380A3 WO 2008075380 A3 WO2008075380 A3 WO 2008075380A3 IN 2007000599 W IN2007000599 W IN 2007000599W WO 2008075380 A3 WO2008075380 A3 WO 2008075380A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
thiazolidine derivatives
pioglitazone
thiazolidine
derivatives
Prior art date
Application number
PCT/IN2007/000599
Other languages
French (fr)
Other versions
WO2008075380A2 (en
Inventor
Venkateswaran Srinivasan Chidambaram
Perminder Singh Johar
Lalit Wadhwa
Original Assignee
Ind-Swift Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind-Swift Laboratories Limited filed Critical Ind-Swift Laboratories Limited
Publication of WO2008075380A2 publication Critical patent/WO2008075380A2/en
Publication of WO2008075380A3 publication Critical patent/WO2008075380A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention relates to an industrially advantageous process for the preparation of thiazolidine derivatives, such as pioglitazone of formula I and its pharmaceutically acceptable salts.This invention also provides novel synthetic intermediates useful in the process for the preparation of pioglitazone.
PCT/IN2007/000599 2006-12-21 2007-12-20 Process for the preparation of thiazolidine derivatives WO2008075380A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN2749/DEL/2006 2006-12-21
IN2749DE2006 2006-12-21
IN1638/DEL/2007 2007-08-01
IN1638DE2007 2007-08-01

Publications (2)

Publication Number Publication Date
WO2008075380A2 WO2008075380A2 (en) 2008-06-26
WO2008075380A3 true WO2008075380A3 (en) 2009-09-17

Family

ID=39536833

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000599 WO2008075380A2 (en) 2006-12-21 2007-12-20 Process for the preparation of thiazolidine derivatives

Country Status (1)

Country Link
WO (1) WO2008075380A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5279449B2 (en) * 2008-10-29 2013-09-04 株式会社トクヤマ Process for producing 5- {4- [2- (5-ethyl-2-pyridyl) ethoxy] benzyl} -2,4-thiazolidinedione hydrochloride
WO2012153312A1 (en) 2011-05-11 2012-11-15 Ranbaxy Laboratories Limited Process for the purification of pioglitazone

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687777A (en) * 1985-01-19 1987-08-18 Takeda Chemical Industries, Ltd. Thiazolidinedione derivatives, useful as antidiabetic agents
US5594015A (en) * 1994-06-22 1997-01-14 Regents Of The University Of California Thiazolidine derivatives for the treatment of psoriasis
US20060167061A1 (en) * 2002-07-16 2006-07-27 Cadila Healthcare Limited Novel process to prepare pioglitazone via several novel intermediates

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687777A (en) * 1985-01-19 1987-08-18 Takeda Chemical Industries, Ltd. Thiazolidinedione derivatives, useful as antidiabetic agents
US5594015A (en) * 1994-06-22 1997-01-14 Regents Of The University Of California Thiazolidine derivatives for the treatment of psoriasis
US20060167061A1 (en) * 2002-07-16 2006-07-27 Cadila Healthcare Limited Novel process to prepare pioglitazone via several novel intermediates

Also Published As

Publication number Publication date
WO2008075380A2 (en) 2008-06-26

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