WO2009140101A3 - Imidazopyridine compounds useful as mmp-13 inhibitors - Google Patents
Imidazopyridine compounds useful as mmp-13 inhibitors Download PDFInfo
- Publication number
- WO2009140101A3 WO2009140101A3 PCT/US2009/042770 US2009042770W WO2009140101A3 WO 2009140101 A3 WO2009140101 A3 WO 2009140101A3 US 2009042770 W US2009042770 W US 2009042770W WO 2009140101 A3 WO2009140101 A3 WO 2009140101A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mmp
- inhibitors
- compounds useful
- imidazopyridine compounds
- imidazopyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Abstract
Disclosed are compounds and compositions of the formula I as described herein which are inhibitors of MMP-13. Also disclosed are methods of using and making compounds of the formula I.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5236008P | 2008-05-12 | 2008-05-12 | |
US61/052,360 | 2008-05-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009140101A2 WO2009140101A2 (en) | 2009-11-19 |
WO2009140101A3 true WO2009140101A3 (en) | 2010-02-25 |
Family
ID=41319256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2009/042770 WO2009140101A2 (en) | 2008-05-12 | 2009-05-05 | Imidazopyridine compounds useful as mmp-13 inhibitors |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009140101A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU1000676D0 (en) | 2010-12-17 | 2011-02-28 | Pharmahungary 2000 Kft | Inhibitors of matrix metalloproteinase, pharmaceutical compositions thereof and use of them for preventing and treating diseases where the activation of mmp is involved |
US20160185774A1 (en) * | 2013-08-02 | 2016-06-30 | Institut Pasteur Korea | Anti-Infective Compounds |
JP7065951B2 (en) | 2017-09-22 | 2022-05-12 | ジュビラント エピパッド エルエルシー | Heterocyclic compound as a PAD inhibitor |
AU2018352142B2 (en) | 2017-10-18 | 2022-08-25 | Jubilant Epipad LLC | Imidazo-pyridine compounds as PAD inhibitors |
US11629135B2 (en) | 2017-11-06 | 2023-04-18 | Jubilant Prodell Llc | Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation |
SG11202004537UA (en) | 2017-11-24 | 2020-06-29 | Jubilant Episcribe Llc | Heterocyclic compounds as prmt5 inhibitors |
KR20200131845A (en) | 2018-03-13 | 2020-11-24 | 주빌런트 프로델 엘엘씨 | Bicyclic compounds as inhibitors of PD1/PD-L1 interaction/activation |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003049738A1 (en) * | 2001-12-08 | 2003-06-19 | Aventis Pharma Deutschland Gmbh | Use of pyridine-2,4-dicarboxylic acid diamides and of pyrimidine-4,6-dicarboxylic acid diamides for selective collagenase inhibition |
WO2007022529A2 (en) * | 2005-08-19 | 2007-02-22 | Array Biopharma Inc. | Method of treating inflammatory diseases |
WO2007139860A2 (en) * | 2006-05-22 | 2007-12-06 | Alantos Pharmaceuticals, Inc. | Heterobicylic metalloprotease inhibitors |
WO2008066789A2 (en) * | 2006-11-27 | 2008-06-05 | H. Lundbeck A/S | Heteroaryl amide derivatives |
-
2009
- 2009-05-05 WO PCT/US2009/042770 patent/WO2009140101A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003049738A1 (en) * | 2001-12-08 | 2003-06-19 | Aventis Pharma Deutschland Gmbh | Use of pyridine-2,4-dicarboxylic acid diamides and of pyrimidine-4,6-dicarboxylic acid diamides for selective collagenase inhibition |
WO2007022529A2 (en) * | 2005-08-19 | 2007-02-22 | Array Biopharma Inc. | Method of treating inflammatory diseases |
WO2007139860A2 (en) * | 2006-05-22 | 2007-12-06 | Alantos Pharmaceuticals, Inc. | Heterobicylic metalloprotease inhibitors |
WO2008066789A2 (en) * | 2006-11-27 | 2008-06-05 | H. Lundbeck A/S | Heteroaryl amide derivatives |
Also Published As
Publication number | Publication date |
---|---|
WO2009140101A2 (en) | 2009-11-19 |
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