BRPI0808340A2 - uso de hemoglobina fetal, hemoglobina fetal, métodos para diagnosticar ou auxiliar a diagnosticar pré-eclampsia, para monitorar a progressão ou regressão de pré-eclampsia, para avaliar a eficácia de um tratamento de pré-eclampsia,para prevenir ou tratar pré-eclampsia, e para prognosticar pré-eclampsia, kit de ensaio, e, uso de uma ou mais substâncias selecionadas dentre agentes de ligação de hemoglobina, agentes de ligação de heme, agentes de degradação de heme e/ou agentes de ligação de ferro - Google Patents

uso de hemoglobina fetal, hemoglobina fetal, métodos para diagnosticar ou auxiliar a diagnosticar pré-eclampsia, para monitorar a progressão ou regressão de pré-eclampsia, para avaliar a eficácia de um tratamento de pré-eclampsia,para prevenir ou tratar pré-eclampsia, e para prognosticar pré-eclampsia, kit de ensaio, e, uso de uma ou mais substâncias selecionadas dentre agentes de ligação de hemoglobina, agentes de ligação de heme, agentes de degradação de heme e/ou agentes de ligação de ferro

Info

Publication number
BRPI0808340A2
BRPI0808340A2 BRPI0808340A BRPI0808340A BRPI0808340A2 BR PI0808340 A2 BRPI0808340 A2 BR PI0808340A2 BR PI0808340 A BRPI0808340 A BR PI0808340A BR PI0808340 A BRPI0808340 A BR PI0808340A BR PI0808340 A2 BRPI0808340 A2 BR PI0808340A2
Authority
BR
Brazil
Prior art keywords
preeclampsia
binding agents
diagnosing
heme
hemoglobin
Prior art date
Application number
BRPI0808340A
Other languages
English (en)
Portuguese (pt)
Inventor
Akerström Bo
Hansson Stefan
Original Assignee
Akerström Bo
Hansson Stefan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akerström Bo, Hansson Stefan filed Critical Akerström Bo
Publication of BRPI0808340A2 publication Critical patent/BRPI0808340A2/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/99Miscellaneous (1.14.99)
    • C12Y114/99003Heme oxygenase (1.14.99.3)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
BRPI0808340A 2007-02-12 2008-02-12 uso de hemoglobina fetal, hemoglobina fetal, métodos para diagnosticar ou auxiliar a diagnosticar pré-eclampsia, para monitorar a progressão ou regressão de pré-eclampsia, para avaliar a eficácia de um tratamento de pré-eclampsia,para prevenir ou tratar pré-eclampsia, e para prognosticar pré-eclampsia, kit de ensaio, e, uso de uma ou mais substâncias selecionadas dentre agentes de ligação de hemoglobina, agentes de ligação de heme, agentes de degradação de heme e/ou agentes de ligação de ferro BRPI0808340A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0700339 2007-02-12
PCT/EP2008/001051 WO2008098734A1 (en) 2007-02-12 2008-02-12 Diagnosis and treatment of preeclampsia

Publications (1)

Publication Number Publication Date
BRPI0808340A2 true BRPI0808340A2 (pt) 2017-05-30

Family

ID=39295873

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0808340A BRPI0808340A2 (pt) 2007-02-12 2008-02-12 uso de hemoglobina fetal, hemoglobina fetal, métodos para diagnosticar ou auxiliar a diagnosticar pré-eclampsia, para monitorar a progressão ou regressão de pré-eclampsia, para avaliar a eficácia de um tratamento de pré-eclampsia,para prevenir ou tratar pré-eclampsia, e para prognosticar pré-eclampsia, kit de ensaio, e, uso de uma ou mais substâncias selecionadas dentre agentes de ligação de hemoglobina, agentes de ligação de heme, agentes de degradação de heme e/ou agentes de ligação de ferro

Country Status (18)

Country Link
US (3) US8568999B2 (enExample)
EP (3) EP2111555B1 (enExample)
JP (2) JP5604111B2 (enExample)
KR (2) KR101608501B1 (enExample)
AU (1) AU2008214837B2 (enExample)
BR (1) BRPI0808340A2 (enExample)
CA (1) CA2674204C (enExample)
DK (2) DK2111555T3 (enExample)
EA (2) EA022609B1 (enExample)
ES (2) ES2599003T3 (enExample)
HR (2) HRP20130809T1 (enExample)
HU (1) HUE031613T2 (enExample)
MX (2) MX2009008408A (enExample)
NZ (1) NZ578077A (enExample)
PL (2) PL2614832T3 (enExample)
PT (2) PT2111555E (enExample)
WO (1) WO2008098734A1 (enExample)
ZA (1) ZA200905101B (enExample)

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EP2313106B1 (en) 2008-07-18 2016-03-30 A1M Pharma AB Medical use of the radical scavenger and antioxidant alpha-1-microglobulin
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AU2011231982B2 (en) 2010-03-24 2014-02-20 Preelumina Diagnostics Ab HbF and A1M as early stage markers for preeclampsia
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CN109072479A (zh) 2015-12-04 2018-12-21 Nx产前公司 使用循环微粒对自发性早产风险进行分层
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EP2313106B1 (en) 2008-07-18 2016-03-30 A1M Pharma AB Medical use of the radical scavenger and antioxidant alpha-1-microglobulin
AU2011231982B2 (en) 2010-03-24 2014-02-20 Preelumina Diagnostics Ab HbF and A1M as early stage markers for preeclampsia

Also Published As

Publication number Publication date
EA031877B1 (ru) 2019-03-29
PL2614832T3 (pl) 2017-01-31
KR20140095572A (ko) 2014-08-01
JP2014012670A (ja) 2014-01-23
MX347788B (es) 2017-05-12
DK2111555T3 (da) 2013-09-02
US8568999B2 (en) 2013-10-29
US20100105070A1 (en) 2010-04-29
ES2599003T3 (es) 2017-01-31
AU2008214837B2 (en) 2013-01-10
PT2111555E (pt) 2013-09-04
EP2613150A1 (en) 2013-07-10
MX2009008408A (es) 2009-11-02
EP2111555B1 (en) 2013-05-29
PT2614832T (pt) 2016-10-18
US10359406B2 (en) 2019-07-23
CA2674204C (en) 2017-07-11
US20140065170A1 (en) 2014-03-06
JP2010518386A (ja) 2010-05-27
DK2614832T3 (da) 2016-10-31
JP5604111B2 (ja) 2014-10-08
EA022609B1 (ru) 2016-02-29
EA200970758A1 (ru) 2010-02-26
EP2614832A1 (en) 2013-07-17
EP2614832B1 (en) 2016-07-13
EP2111555A1 (en) 2009-10-28
JP5792772B2 (ja) 2015-10-14
HUE031613T2 (en) 2017-09-28
HRP20130809T1 (xx) 2013-10-11
ZA200905101B (en) 2012-01-25
NZ578077A (en) 2012-04-27
US20180284087A1 (en) 2018-10-04
KR20100015315A (ko) 2010-02-12
PL2111555T3 (pl) 2013-10-31
KR101608501B1 (ko) 2016-04-04
ES2426069T3 (es) 2013-10-21
AU2008214837A1 (en) 2008-08-21
WO2008098734A1 (en) 2008-08-21
KR101454013B1 (ko) 2014-11-12
HRP20161266T1 (hr) 2016-12-16
EA201500335A1 (ru) 2016-08-31
CA2674204A1 (en) 2008-08-21

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