BRPI0807601B8 - método para identificação de um paciente que esteja em risco com relação ao desenvolvimento de um distúrbio na tireoide e uso de um agente depletivo de linfócitos - Google Patents
método para identificação de um paciente que esteja em risco com relação ao desenvolvimento de um distúrbio na tireoide e uso de um agente depletivo de linfócitosInfo
- Publication number
- BRPI0807601B8 BRPI0807601B8 BRPI0807601A BRPI0807601A BRPI0807601B8 BR PI0807601 B8 BRPI0807601 B8 BR PI0807601B8 BR PI0807601 A BRPI0807601 A BR PI0807601A BR PI0807601 A BRPI0807601 A BR PI0807601A BR PI0807601 B8 BRPI0807601 B8 BR PI0807601B8
- Authority
- BR
- Brazil
- Prior art keywords
- patient
- thyroid
- risk
- identifying
- development
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70592—CD52
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/046—Thyroid disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90173207P | 2007-02-16 | 2007-02-16 | |
US60/901,732 | 2007-02-16 | ||
PCT/US2008/002047 WO2008103292A1 (en) | 2007-02-16 | 2008-02-15 | Method of identifying risk for thyroid disorder |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0807601A2 BRPI0807601A2 (pt) | 2014-05-06 |
BRPI0807601B1 BRPI0807601B1 (pt) | 2021-02-23 |
BRPI0807601B8 true BRPI0807601B8 (pt) | 2021-07-27 |
Family
ID=39434244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0807601A BRPI0807601B8 (pt) | 2007-02-16 | 2008-02-15 | método para identificação de um paciente que esteja em risco com relação ao desenvolvimento de um distúrbio na tireoide e uso de um agente depletivo de linfócitos |
Country Status (22)
Country | Link |
---|---|
US (3) | US20100136587A1 (pt) |
EP (2) | EP2130044B1 (pt) |
JP (2) | JP5662684B2 (pt) |
CN (2) | CN108303546B (pt) |
AU (1) | AU2008219097B2 (pt) |
BR (1) | BRPI0807601B8 (pt) |
CA (1) | CA2678199A1 (pt) |
CY (1) | CY1118663T1 (pt) |
DK (1) | DK2130044T3 (pt) |
ES (1) | ES2612558T3 (pt) |
HK (1) | HK1257419A1 (pt) |
HR (1) | HRP20170121T1 (pt) |
HU (1) | HUE031421T2 (pt) |
IL (2) | IL200314A (pt) |
LT (1) | LT2130044T (pt) |
MX (1) | MX2009008642A (pt) |
PL (1) | PL2130044T3 (pt) |
PT (1) | PT2130044T (pt) |
RS (1) | RS55636B1 (pt) |
RU (1) | RU2013120485A (pt) |
SI (1) | SI2130044T1 (pt) |
WO (1) | WO2008103292A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9498528B2 (en) * | 2006-09-13 | 2016-11-22 | Genzyme Corporation | Treatment of multiple sclerosis (MS) |
FR2934129B1 (fr) * | 2008-07-24 | 2014-05-02 | Oreal | Procede de traitement cosmetique. |
CA2729978A1 (en) * | 2008-09-19 | 2010-03-25 | University Of Utah Research Foundation | Methods for identification and prediction of multiple sclerosis disease and therapy response |
CN106257288A (zh) * | 2016-08-15 | 2016-12-28 | 余洋 | 一种血清TPOAb IgG4水平检测方法 |
CN112312921A (zh) | 2018-07-02 | 2021-02-02 | 美国西门子医学诊断股份有限公司 | 新型甲状腺过氧化物酶自身抗体免疫测定 |
KR102469743B1 (ko) * | 2020-06-10 | 2022-11-22 | 주식회사 타이로스코프 | 약물 복용에 따른 갑상선 기능 모니터링 방법, 이를 수행하는 모니터링 서버 및 사용자 단말 |
EP4001919A1 (en) * | 2020-11-13 | 2022-05-25 | Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal | Predictive biomarkers of autoimmunity in patients treated with alemtuzumab |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5846534A (en) * | 1988-02-12 | 1998-12-08 | British Technology Group Limited | Antibodies to the antigen campath-1 |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
GB9125768D0 (en) * | 1991-12-04 | 1992-02-05 | Hale Geoffrey | Therapeutic method |
GB2265713A (en) * | 1992-05-16 | 1993-10-06 | R S R Limited | Assay for autoantibodies against thyroglobulin or thyroid peroxidase |
DE19710211C2 (de) * | 1997-03-12 | 1999-12-16 | Brahms Diagnostica Gmbh | Verfahren zur Bestimmung von Schilddrüsen-Autoantikörpern |
GB9823397D0 (en) * | 1998-10-27 | 1998-12-23 | Rsr Ltd | Assays for thyroid autoantibodies |
WO2006044332A2 (en) * | 2004-10-12 | 2006-04-27 | Carantech, Inc. | Animal model systems for viral pathogenesis of neurodegeneration, autoimmune demyelination, and diabetes |
US9498528B2 (en) * | 2006-09-13 | 2016-11-22 | Genzyme Corporation | Treatment of multiple sclerosis (MS) |
-
2008
- 2008-02-15 EP EP08725657.4A patent/EP2130044B1/en active Active
- 2008-02-15 EP EP12176625A patent/EP2538217A1/en not_active Withdrawn
- 2008-02-15 ES ES08725657.4T patent/ES2612558T3/es active Active
- 2008-02-15 JP JP2009549628A patent/JP5662684B2/ja active Active
- 2008-02-15 AU AU2008219097A patent/AU2008219097B2/en active Active
- 2008-02-15 LT LTEP08725657.4T patent/LT2130044T/lt unknown
- 2008-02-15 PT PT87256574T patent/PT2130044T/pt unknown
- 2008-02-15 RS RS20170083A patent/RS55636B1/sr unknown
- 2008-02-15 HU HUE08725657A patent/HUE031421T2/hu unknown
- 2008-02-15 DK DK08725657.4T patent/DK2130044T3/en active
- 2008-02-15 CN CN201810058824.2A patent/CN108303546B/zh active Active
- 2008-02-15 US US12/526,129 patent/US20100136587A1/en not_active Abandoned
- 2008-02-15 BR BRPI0807601A patent/BRPI0807601B8/pt active IP Right Grant
- 2008-02-15 CA CA002678199A patent/CA2678199A1/en not_active Withdrawn
- 2008-02-15 MX MX2009008642A patent/MX2009008642A/es active IP Right Grant
- 2008-02-15 WO PCT/US2008/002047 patent/WO2008103292A1/en active Application Filing
- 2008-02-15 PL PL08725657T patent/PL2130044T3/pl unknown
- 2008-02-15 CN CN200880012149.4A patent/CN101657721B/zh active Active
- 2008-02-15 SI SI200831753A patent/SI2130044T1/sl unknown
-
2009
- 2009-08-10 IL IL200314A patent/IL200314A/en active IP Right Grant
-
2012
- 2012-12-05 US US13/705,944 patent/US9664688B2/en active Active
-
2013
- 2013-05-06 RU RU2013120485/15A patent/RU2013120485A/ru not_active Application Discontinuation
-
2014
- 2014-05-28 JP JP2014110361A patent/JP6058585B2/ja active Active
-
2015
- 2015-11-02 IL IL242391A patent/IL242391A/en active IP Right Grant
-
2017
- 2017-01-25 HR HRP20170121TT patent/HRP20170121T1/hr unknown
- 2017-01-26 CY CY20171100113T patent/CY1118663T1/el unknown
- 2017-05-10 US US15/591,547 patent/US10648986B2/en active Active
-
2018
- 2018-12-27 HK HK18116630.2A patent/HK1257419A1/zh unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0807601B8 (pt) | método para identificação de um paciente que esteja em risco com relação ao desenvolvimento de um distúrbio na tireoide e uso de um agente depletivo de linfócitos | |
BR112013027867A2 (pt) | "método de detectar o nível de um anticorpo anti-ip10 em amostra, anticorpo monoclonal isolado ou porção de ligação de antígeno do mesmo, linhagem de célula de hibridoma e kit" | |
BRPI0818437B8 (pt) | anticorpo ou fragmento funcional do anticorpo, composição farmacêutica, uso de pelo menos um dos anticorpos ou fragmentos funcionais dos anticorpos, e, hibridoma | |
BR112012012160A2 (pt) | material e métodos para tratar ou prevenir doenças associadas ao her-3 | |
BR112015023425A2 (pt) | método e composição para coloração e processamento de uma amostra de urina | |
BRPI0510224A (pt) | métodos de prevenção de doença autoimunológica e artigo industrializado | |
BR112014018331A8 (pt) | Biomarcadores e terapias combinadas usando vírus oncolítico e imunomodulação | |
BRPI0414435A (pt) | métodos e reagentes para o tratamento de distúrbios imunoinflamatórios | |
BRPI0606557A2 (pt) | método de inibição do abrigo de her2, método de redução do nìvel em soro de domìnio extracelular (ecd) de her2 em mamìferos, métodos de tratamento de cáncer em mamìferos, método de redução do nìvel de p95 her2 em célula e método de diagnóstico | |
CR20110296A (es) | Anticuerpos humanos de alta afinidad contra pcsk9 | |
BRPI0507645A (pt) | anticorpo, método de detectar um distúrbio ósseo metabólico, kit para detectar um distúrbio ósseo metabólico, composição farmacêutica para o tratamento de um distúrbio ósseo metabólico, e, método de triar uma substáncia efetiva para tratar e/ou prevenir um distúrbio ósseo metabólico | |
BRPI0516437A (pt) | utilização de uma quantidade eficaz de pelo menos um microorganismo, processo de tratamento cosmético, composição cosmética e/ou dermatológica e composição para absorção oral | |
BR112012019693A2 (pt) | anticorpos que se ligam à lisil oxidase-like 2 (loxl2) e métodos de uso para eles. | |
BRPI0907303A2 (pt) | "artigos absorventes capazes de indicar a presença de urina" | |
BRPI0410261A (pt) | método de detecção de probnp natural | |
MA33256B1 (fr) | Anticorps et immunoconjugués anti-fcrh5 et procédés d'utilisation | |
EA200971131A1 (ru) | Биомаркеры для прогнозирования чувствительности или отсутствия чувствительности к анти-фно агентам | |
BRPI0411020A (pt) | perfil de expressão de gene, métodos de identificar agentes modulares do caminho de wnt, de preparar um perfil de expressão de gene, de triar um agente que realce a remodelagem associada com a carga óssea e reagentes que se ligam às proteìnas que modulam a remodelagem óssea e/ou mineralização óssea, de tratar uma doença ou distúrbio de mineralização óssea, de modular a mineralização óssea em uma célula e a mineralização óssea e/ou remodelagem óssea em um paciente e de determinar se um composto ou uma composição realçam o efeito de carga óssea na atividade/função e/ou mineralização da célula óssea, agente candidato para tratar uma condição de massa óssea baixa e composição | |
BRPI0906549A8 (pt) | bandagem médica | |
BRPI0210579B8 (pt) | anticorpo e composição farmacêutica | |
BR112022007386A2 (pt) | Métodos para tratar um câncer hematológico e o uso de biomarcadores companheiros para 2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)benzil)amino)isoindolina-1,3-diona | |
BRPI0606148A2 (pt) | anticorpos monoclonais neutralizantes contra a sìndrome respiratória aguda grave associada com o coronavìrus | |
BRPI0817427A8 (pt) | anticorpo anti-bst2 | |
BR112014007253A2 (pt) | uso de anticorpos que se ligam a il-1beta | |
BR112012005670A2 (pt) | ''método para a identificação de um paciente com câncer que pode se beneficiar com a terapia antiagiogênica, método para a predição da responsividade de um paciente com câncer à terapia antiangiogênica, uso de um anticorpo anto- vegf para melhorar o efeito do tratamento de um paciente sofrendo de câncer, método ou uso, kit útil para realizar o método, uso de uma proteína ou usom kit útil para realizar o método, uso de uma proteína ou oligonucleotídeo ou matriz de polinecleotídeo para determinar o nível de expressão de bfgf em um método e kit ou uso |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 23/02/2021, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/02/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO |