BRPI0720604B8 - composição e método para detecção de desmineralização - Google Patents

composição e método para detecção de desmineralização

Info

Publication number
BRPI0720604B8
BRPI0720604B8 BRPI0720604A BRPI0720604A BRPI0720604B8 BR PI0720604 B8 BRPI0720604 B8 BR PI0720604B8 BR PI0720604 A BRPI0720604 A BR PI0720604A BR PI0720604 A BRPI0720604 A BR PI0720604A BR PI0720604 B8 BRPI0720604 B8 BR PI0720604B8
Authority
BR
Brazil
Prior art keywords
composition
demineralization
detecting
detecting demineralization
Prior art date
Application number
BRPI0720604A
Other languages
English (en)
Portuguese (pt)
Inventor
Longbottom Chris
Perfect Emma
Original Assignee
Calcivis Ltd
Lux Innovate Ltd
The Univ Court Of The Univ Of Dundee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calcivis Ltd, Lux Innovate Ltd, The Univ Court Of The Univ Of Dundee filed Critical Calcivis Ltd
Publication of BRPI0720604A2 publication Critical patent/BRPI0720604A2/pt
Publication of BRPI0720604A8 publication Critical patent/BRPI0720604A8/pt
Publication of BRPI0720604B1 publication Critical patent/BRPI0720604B1/pt
Publication of BRPI0720604B8 publication Critical patent/BRPI0720604B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/006Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cosmetics (AREA)
BRPI0720604A 2006-12-21 2007-12-21 composição e método para detecção de desmineralização BRPI0720604B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0625678.8A GB0625678D0 (en) 2006-12-21 2006-12-21 Composition and method for detection of demineralisation
PCT/GB2007/004944 WO2008075081A2 (en) 2006-12-21 2007-12-21 Composition and method for detection of demineralisation

Publications (4)

Publication Number Publication Date
BRPI0720604A2 BRPI0720604A2 (pt) 2014-04-08
BRPI0720604A8 BRPI0720604A8 (pt) 2017-02-21
BRPI0720604B1 BRPI0720604B1 (pt) 2018-07-17
BRPI0720604B8 true BRPI0720604B8 (pt) 2021-07-27

Family

ID=37734727

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0720604A BRPI0720604B8 (pt) 2006-12-21 2007-12-21 composição e método para detecção de desmineralização

Country Status (12)

Country Link
US (3) US10441667B2 (zh)
EP (2) EP2125035B1 (zh)
JP (2) JP5711462B2 (zh)
CN (2) CN108465113A (zh)
AU (1) AU2007336024B2 (zh)
BR (1) BRPI0720604B8 (zh)
CA (1) CA2682960C (zh)
DK (1) DK2125035T3 (zh)
ES (1) ES2524782T3 (zh)
GB (2) GB0625678D0 (zh)
PL (1) PL2125035T3 (zh)
WO (1) WO2008075081A2 (zh)

Families Citing this family (16)

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GB201011913D0 (en) * 2010-07-15 2010-09-01 Lux Innovate Ltd Detecting device
WO2013056071A1 (en) 2011-10-14 2013-04-18 Beam Technologies, Llc Oral health care implement and system with oximetry sensor
CN102519886A (zh) * 2011-12-19 2012-06-27 浙江大学 一种检测农作物叶片中叶绿素a和类胡萝卜素含量的方法
US11273113B2 (en) 2012-04-27 2022-03-15 Stichting Vu Protection of materials by sphingosine based compounds
CA2894435A1 (en) * 2012-12-12 2014-06-19 Promega Corporation Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
US9662276B2 (en) 2015-06-16 2017-05-30 President And Fellows Of Harvard College Methodology of dental caries detection
US9310355B1 (en) * 2015-06-16 2016-04-12 President And Fellows Of Harvard College Methodology of dental caries detection
CN106446599A (zh) * 2015-08-11 2017-02-22 中国科学院青岛生物能源与过程研究所 一种筛选婴幼儿龋病的口腔致病性生物标记物的方法
KR101868118B1 (ko) * 2016-11-09 2018-06-15 이선미 충치진단키트
GB201700317D0 (en) 2017-01-09 2017-02-22 Calcivis Ltd Detection device
DE102017205012A1 (de) * 2017-03-24 2018-09-27 Henkel Ag & Co. Kgaa Verfahren und Anordnung zum Ermitteln einer nicht-therapeutischen Behandlung von Zähnen
KR102626317B1 (ko) 2017-07-24 2024-01-18 퀀텀-에스아이 인코포레이티드 고강도 표지된 반응물 조성물 및 서열분석 방법
JP7148136B2 (ja) * 2019-01-17 2022-10-05 国立大学法人大阪大学 水の硬度の測定
EP3914603A1 (en) 2019-01-23 2021-12-01 Quantum-Si Incorporated High intensity labeled reactant compositions and methods for sequencing
US11793452B2 (en) 2019-10-03 2023-10-24 Johnson & Johnson Consumer Inc. Method of visualizing and quantifying remineralization
JP7141163B1 (ja) 2022-07-15 2022-09-22 株式会社スクリエ 酸蝕症検出システム、酸蝕症検出方法及びそのプログラム

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JPS5576821A (en) * 1978-12-04 1980-06-10 Kuraray Co Ltd Reagent for discriminating decayed part of tooth
US4290433A (en) 1979-08-20 1981-09-22 Alfano Robert R Method and apparatus for detecting the presence of caries in teeth using visible luminescence
FI901681A0 (fi) * 1989-04-10 1990-04-03 Ela Technologies Inc Foerfarande foer oekning av kaensligheten hos luminescensanalyser.
US5240697A (en) * 1991-10-17 1993-08-31 Colgate-Palmolive Company Desensitizing anti-tartar dentifrice
US5409835A (en) * 1992-12-30 1995-04-25 The University Of Maryland At Baltimore Long-wavelength fluorescent probe compounds for calcium ions and their use in ratiometrically measuring calcium ion concentrations
US5604198A (en) * 1994-05-12 1997-02-18 Poduslo; Joseph F. Method to enhance permeability of the blood/brain blood/nerve barriers to therapeutic agents
JP3967415B2 (ja) 1997-02-28 2007-08-29 株式会社クラレ 抗菌性の齲蝕検知液
AU5275100A (en) * 1999-05-21 2000-12-12 Regents Of The University Of California, The Fluorescent protein indicators
DE19926728B4 (de) 1999-06-11 2011-08-18 3M Espe Ag, 82229 Verwendung von Trägermaterialien und diagnostisch nutzbaren Zusatzstoffen in Abbildungsverfahren für intraorale Diagnosezwecke
JP3760222B2 (ja) 2000-05-25 2006-03-29 国立大学法人名古屋大学 トビイカ発光蛋白質、トビイカ発光蛋白質をコードする遺伝子
JP5389307B2 (ja) * 2000-06-01 2014-01-15 インスティチュート・パスツール 単細胞レベルでの生物発光性Ca++リポーターとしてのキメラ性GFP−エクオリン
US6769911B2 (en) 2001-04-16 2004-08-03 Advanced Research & Technology Institue Luminescence assisted caries excavation
AU2003224694A1 (en) 2002-03-25 2003-10-13 Chemicon International Inc. Modified aequorins having enhanced glowing kinetics and methods of using same
JP4025601B2 (ja) 2002-08-13 2007-12-26 株式会社堀場製作所 う蝕歯診断方法および装置
JP4232562B2 (ja) 2002-09-09 2009-03-04 チッソ株式会社 カルシウム結合型発光蛋白質が分散している吸水性高分子ゲル組成物、およびこれを含有する化粧料、並びにこれらの連続発光方法
CA2503347A1 (en) * 2002-10-15 2004-04-29 The Regents Of The University Of California Monoclonal antibodies specific for cariogenic bacteria
DK1413584T3 (da) * 2002-10-21 2005-07-04 Axxam S R L Fotoprotein med forbedret bioluminescens
DE10311769A1 (de) 2003-03-18 2004-09-30 Bayer Healthcare Ag Testmethoden zur Bestimmung der intrazellulären Konzentration zyklischer Nukleotide
US20050058602A1 (en) * 2003-09-11 2005-03-17 The Procter & Gamble Company Dye composition and method for detection of demineralized lesions in teeth
JPWO2005036178A1 (ja) * 2003-10-15 2006-12-21 独立行政法人理化学研究所 Fretを利用した蛍光指示薬
JP2005168463A (ja) 2003-12-15 2005-06-30 Chisso Corp カルシウム結合型発光蛋白質の保存方法等
WO2005078445A1 (en) * 2004-02-12 2005-08-25 Institut Pasteur Non-invasive real-time in vivo bioluminescence imaging of local ca2+ dynamics in living organisms
US7796243B2 (en) 2004-06-09 2010-09-14 National Research Council Of Canada Detection and monitoring of changes in mineralized tissues or calcified deposits by optical coherence tomography and Raman spectroscopy
US20060229243A1 (en) 2004-06-21 2006-10-12 Quincy Resource Group, Inc. Aequorin-containing compositions and methods of using same
EP1700865A1 (en) 2005-03-11 2006-09-13 AXXAM S.r.l. Photoproteins with enhanced bioluminescence and their use as intracellular calcium indicators
CN103819538A (zh) * 2005-09-28 2014-05-28 加利福尼亚大学董事会 钙结合肽
US20070238996A1 (en) 2006-03-14 2007-10-11 The Research Foundation Of State University Of New York Portable ultrasonic device and method for diagnosis of dental caries
US20080038686A1 (en) * 2006-04-18 2008-02-14 Shigemi Nagai Methods and kits for early stage caries detection

Also Published As

Publication number Publication date
US20180243449A1 (en) 2018-08-30
AU2007336024B2 (en) 2013-07-11
ES2524782T3 (es) 2014-12-12
CN108465113A (zh) 2018-08-31
EP2125035B1 (en) 2014-10-08
US20100034750A1 (en) 2010-02-11
JP2010529415A (ja) 2010-08-26
BRPI0720604A8 (pt) 2017-02-21
WO2008075081A2 (en) 2008-06-26
BRPI0720604B1 (pt) 2018-07-17
CN101951961B (zh) 2018-04-27
GB0625678D0 (en) 2007-01-31
US10441667B2 (en) 2019-10-15
BRPI0720604A2 (pt) 2014-04-08
AU2007336024A1 (en) 2008-06-26
CN101951961A (zh) 2011-01-19
EP2125035A2 (en) 2009-12-02
GB2445460A (en) 2008-07-09
CA2682960A1 (en) 2008-06-26
PL2125035T3 (pl) 2015-03-31
JP5711462B2 (ja) 2015-04-30
WO2008075081A3 (en) 2009-04-02
DK2125035T3 (en) 2015-01-12
JP2014055132A (ja) 2014-03-27
EP2682132A1 (en) 2014-01-08
GB0725089D0 (en) 2008-01-30
US11878066B2 (en) 2024-01-23
US20240108763A1 (en) 2024-04-04
CA2682960C (en) 2016-07-26

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Legal Events

Date Code Title Description
B25C Requirement related to requested transfer of rights

Owner name: LUX BIOTECHNOLOGY LIMITED (GB) , THE UNIVERSITY CO

Free format text: A FIM DE ATENDER A TRANSFERENCIA, REQUERIDA ATRAVES DA PETICAO NO 860150192481 DE 28/08/2015, E NECESSARIO ESCLARECER A DIVERGENCIA ENTRE O NOME DE UMA DAS TITULARES DO PEDIDO E O NOME QUE CONSTA COMO UMA DAS CEDENTES.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: CALCIVIS LIMITED (GB)

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/12/2007, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO