BRPI0718135A2 - Derivadois de heterociclil piridil sulfonamida, sua produção e uso como agentes farmacêuticos - Google Patents

Derivadois de heterociclil piridil sulfonamida, sua produção e uso como agentes farmacêuticos

Info

Publication number
BRPI0718135A2
BRPI0718135A2 BRPI0718135-3A2A BRPI0718135A BRPI0718135A2 BR PI0718135 A2 BRPI0718135 A2 BR PI0718135A2 BR PI0718135 A BRPI0718135 A BR PI0718135A BR PI0718135 A2 BRPI0718135 A2 BR PI0718135A2
Authority
BR
Brazil
Prior art keywords
hyperocyclyl
pyridyl
production
pharmaceutical agents
sulphonamide derivatives
Prior art date
Application number
BRPI0718135-3A2A
Other languages
English (en)
Inventor
Frederick Brookfield
Jonathan Gridley
Lothar Kling
Michael Prime
Ulrike Reiff
Der Saal Wolfgang Von
Hirschheydt Thomas Von
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0718135A2 publication Critical patent/BRPI0718135A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
BRPI0718135-3A2A 2006-10-26 2007-10-24 Derivadois de heterociclil piridil sulfonamida, sua produção e uso como agentes farmacêuticos BRPI0718135A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06022365 2006-10-26
PCT/EP2007/009238 WO2008049605A1 (en) 2006-10-26 2007-10-24 Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents

Publications (1)

Publication Number Publication Date
BRPI0718135A2 true BRPI0718135A2 (pt) 2013-11-05

Family

ID=37909782

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718135-3A2A BRPI0718135A2 (pt) 2006-10-26 2007-10-24 Derivadois de heterociclil piridil sulfonamida, sua produção e uso como agentes farmacêuticos

Country Status (11)

Country Link
US (1) US7939532B2 (pt)
EP (1) EP2079719A1 (pt)
JP (1) JP5133996B2 (pt)
KR (1) KR101096475B1 (pt)
CN (1) CN101522651B (pt)
AU (1) AU2007308340A1 (pt)
BR (1) BRPI0718135A2 (pt)
CA (1) CA2666885A1 (pt)
IL (1) IL197013A0 (pt)
MX (1) MX2009004187A (pt)
WO (1) WO2008049605A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939532B2 (en) 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1477664A (en) * 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
CA2110524A1 (en) * 1992-12-10 1994-06-11 Gerald Burr Grindey Antitumor compositions and methods of treatment
CZ20033296A3 (cs) * 2001-06-06 2004-04-14 Eli Lilly And Company Benzoylsulfonamidy a sulfonylbenzamidiny jako protinádorové sloučeniny
ES2324705T3 (es) 2001-09-27 2009-08-13 Universite De Liege Derivados sulfonamida piridinicos, metodo de produccion y su uso.
TWI281916B (en) 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
US7282595B2 (en) 2002-11-22 2007-10-16 Eli Lilly And Company Antitumor benzoylsulfonamides
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US7939532B2 (en) 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents

Also Published As

Publication number Publication date
JP5133996B2 (ja) 2013-01-30
IL197013A0 (en) 2009-11-18
AU2007308340A1 (en) 2008-05-02
CN101522651B (zh) 2011-11-16
JP2010502666A (ja) 2010-01-28
EP2079719A1 (en) 2009-07-22
KR101096475B1 (ko) 2011-12-20
CN101522651A (zh) 2009-09-02
WO2008049605A1 (en) 2008-05-02
CA2666885A1 (en) 2008-05-02
US20100292247A1 (en) 2010-11-18
KR20090071621A (ko) 2009-07-01
MX2009004187A (es) 2009-04-30
US7939532B2 (en) 2011-05-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2277 DE 26/08/2014.