BRPI0708071A8 - Derivados de catecolamina deuterada e medicamentos compreendendo os ditos compostos - Google Patents
Derivados de catecolamina deuterada e medicamentos compreendendo os ditos compostosInfo
- Publication number
- BRPI0708071A8 BRPI0708071A8 BRPI0708071A BRPI0708071A BRPI0708071A8 BR PI0708071 A8 BRPI0708071 A8 BR PI0708071A8 BR PI0708071 A BRPI0708071 A BR PI0708071A BR PI0708071 A BRPI0708071 A BR PI0708071A BR PI0708071 A8 BRPI0708071 A8 BR PI0708071A8
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- catecholamine derivatives
- deuterated catecholamine
- drugs including
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006008316.4 | 2006-02-17 | ||
DE102006008316 | 2006-02-17 | ||
PCT/EP2007/001555 WO2007093450A2 (en) | 2006-02-17 | 2007-02-16 | Deuterated catecholamine derivatives and medicaments comprising said compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0708071A2 BRPI0708071A2 (pt) | 2011-05-17 |
BRPI0708071A8 true BRPI0708071A8 (pt) | 2017-12-26 |
Family
ID=38236462
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0708071A BRPI0708071A8 (pt) | 2006-02-17 | 2007-02-16 | Derivados de catecolamina deuterada e medicamentos compreendendo os ditos compostos |
Country Status (24)
Country | Link |
---|---|
US (2) | USRE46555E1 (pt) |
EP (2) | EP1991522B1 (pt) |
JP (1) | JP5248331B2 (pt) |
KR (1) | KR101411422B1 (pt) |
CN (1) | CN101384545B (pt) |
AU (1) | AU2007214622B2 (pt) |
BR (1) | BRPI0708071A8 (pt) |
CA (1) | CA2642593C (pt) |
CY (1) | CY1117995T1 (pt) |
DK (1) | DK1991522T3 (pt) |
EA (1) | EA017983B1 (pt) |
ES (1) | ES2587368T3 (pt) |
HR (1) | HRP20161039T1 (pt) |
HU (1) | HUE028777T2 (pt) |
IL (1) | IL193102A (pt) |
LT (1) | LT1991522T (pt) |
ME (1) | ME02508B (pt) |
PL (1) | PL1991522T3 (pt) |
PT (1) | PT1991522T (pt) |
RS (1) | RS55142B1 (pt) |
SI (1) | SI1991522T1 (pt) |
UA (1) | UA97795C2 (pt) |
WO (1) | WO2007093450A2 (pt) |
ZA (1) | ZA200806568B (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
PL2303330T5 (pl) | 2008-06-06 | 2021-10-25 | Pharma Two B Ltd. | Kompozycje farmaceutyczne do leczenia choroby Parkinsona |
BRPI0916769A2 (pt) | 2008-07-15 | 2017-09-26 | Theracos Inc | derivados de benzilbenzeno deuterados e métodos de uso |
WO2013127831A1 (en) | 2012-02-28 | 2013-09-06 | Grünenthal GmbH | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
US9550780B2 (en) | 2012-09-18 | 2017-01-24 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
JP6362601B2 (ja) | 2012-09-18 | 2018-07-25 | オースペックス・ファーマシューティカルズ・インコーポレイテッドAuspex Pharmaceuticals, Inc. | 小胞モノアミン輸送体2の重水素化ベンゾキノリン阻害剤の製剤薬物動態 |
US9763904B2 (en) | 2013-02-05 | 2017-09-19 | Teva Pharmaceuticals International Gmbh | Position-specific asymmetric deuterium enriched catecholamine derivatives and medicaments comprising said compounds |
BR112015016889A8 (pt) * | 2013-02-05 | 2018-01-23 | Imphar Ag | derivados de catecolamina enriquecidos com deutério em posição específica |
WO2014174425A2 (en) * | 2013-04-24 | 2014-10-30 | Mahesh Kandula | Compositions and methods for the treatment of orthostasis and neurological diseases |
PE20160556A1 (es) * | 2013-07-08 | 2016-06-11 | Auspex Pharmaceuticals Inc | Compuestos neurotransmisores de dihidroxifenilo, composiciones y metodos |
JP2017503756A (ja) * | 2013-11-22 | 2017-02-02 | オースペックス ファーマシューティカルズ インコーポレイテッド | 異常な筋活動を処置する方法 |
MX369956B (es) | 2013-12-03 | 2019-11-27 | Auspex Pharmaceuticals Inc | Metodos para preparar compuestos de benzoquinolina. |
WO2015120110A2 (en) | 2014-02-07 | 2015-08-13 | Auspex Pharmaceuticals, Inc. | Novel pharmaceutical formulations |
EP2918266A1 (en) | 2014-03-11 | 2015-09-16 | CDRD Berolina AB | Composition comprising a dopamine agonist and an L-DOPA derivative for treating Parkinson's disease |
GB201420341D0 (en) * | 2014-11-17 | 2014-12-31 | Evolution Valves Ltd | Valve arrangement |
MX2017011459A (es) | 2015-03-06 | 2018-04-24 | Auspex Pharmaceuticals Inc | Metodos para el tratamiento de trastornos del movimiento involuntario anormal. |
CN106343013A (zh) * | 2015-07-19 | 2017-01-25 | 中国科学院上海有机化学研究所 | 一种粮食储存方法 |
AR106313A1 (es) | 2015-10-09 | 2018-01-03 | Teva Pharmaceuticals Int Gmbh | Combinación de levodopa deuterada con carbidopa y opicapona para el tratamiento de enfermedad de parkinson |
CN105360267B (zh) * | 2015-10-09 | 2017-11-10 | 青岛振坤食品机械有限公司 | 一种全自动穿串机 |
CN105862897B (zh) * | 2016-04-11 | 2018-01-16 | 江苏省华建建设股份有限公司 | 砂质泥岩地基浅基础原槽浇筑施工工法 |
AU2019392924A1 (en) * | 2018-12-06 | 2021-06-17 | Senda Biosciences, Inc | Quaternary ammonium salts as inhibitors of trimethylamine production |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3699158A (en) | 1969-08-25 | 1972-10-17 | Merck & Co Inc | Selective deuteration of tyrosine, aspartic and glutamic acids |
DE2049807A1 (en) | 1970-10-10 | 1972-04-13 | Hartmeyer H | Conversion of closed cell plastics foam to - open cell structure |
DE2049115C3 (de) | 1970-10-06 | 1981-07-30 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo | Verwendung von Calcium-5-butylpicolinat und/oder Calcium-5-pentylpicolinat bei der Bekämpfung des Parkinsonismus mit 3-(3,4-Dihydroxyphenyl)-L-alanin (L-Dopa) |
ATE76747T1 (de) * | 1986-06-10 | 1992-06-15 | Chiesi Farma Spa | Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen. |
IT1226902B (it) | 1988-07-12 | 1991-02-21 | Mini Ricerca Scient Tecnolog | Processo per la sintesi del levodopa |
US5354885A (en) * | 1992-12-24 | 1994-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Process for preparing ethyl ester of L-DOPA |
US6221335B1 (en) * | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
US6440710B1 (en) * | 1998-12-10 | 2002-08-27 | The Scripps Research Institute | Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds |
DK1104760T3 (da) * | 1999-12-03 | 2003-06-30 | Pfizer Prod Inc | Sulfamoylheteroarylpyrazolforbindelser som anti-inflammatoriske/analgetiske midler |
DE10261808A1 (de) | 2002-12-19 | 2004-07-08 | Turicum Drug Development Ag | Verwendung von L-DOPA, seiner Derivate und diese Verbindungen enthaltender Arzneimittel zur Prophylaxe psychotischer Erkrankungen |
DE10261807A1 (de) | 2002-12-19 | 2004-07-01 | Turicum Drug Development Ag | Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel |
-
2007
- 2007-02-16 RS RS20160674A patent/RS55142B1/sr unknown
- 2007-02-16 WO PCT/EP2007/001555 patent/WO2007093450A2/en active Application Filing
- 2007-02-16 PL PL07703542T patent/PL1991522T3/pl unknown
- 2007-02-16 EP EP07703542.6A patent/EP1991522B1/en active Active
- 2007-02-16 CA CA2642593A patent/CA2642593C/en active Active
- 2007-02-16 US US14/464,568 patent/USRE46555E1/en active Active
- 2007-02-16 UA UAA200811184A patent/UA97795C2/uk unknown
- 2007-02-16 KR KR1020087022011A patent/KR101411422B1/ko active IP Right Grant
- 2007-02-16 LT LTEP07703542.6T patent/LT1991522T/lt unknown
- 2007-02-16 CN CN200780005912.6A patent/CN101384545B/zh not_active Expired - Fee Related
- 2007-02-16 US US12/224,120 patent/US8247603B2/en not_active Ceased
- 2007-02-16 DK DK07703542.6T patent/DK1991522T3/en active
- 2007-02-16 JP JP2008554702A patent/JP5248331B2/ja not_active Expired - Fee Related
- 2007-02-16 ES ES07703542.6T patent/ES2587368T3/es active Active
- 2007-02-16 EA EA200801826A patent/EA017983B1/ru not_active IP Right Cessation
- 2007-02-16 HU HUE07703542A patent/HUE028777T2/en unknown
- 2007-02-16 ME MEP-2016-167A patent/ME02508B/me unknown
- 2007-02-16 SI SI200731819A patent/SI1991522T1/sl unknown
- 2007-02-16 EP EP16170031.5A patent/EP3101001B1/en active Active
- 2007-02-16 AU AU2007214622A patent/AU2007214622B2/en not_active Ceased
- 2007-02-16 PT PT77035426T patent/PT1991522T/pt unknown
- 2007-02-16 BR BRPI0708071A patent/BRPI0708071A8/pt not_active Application Discontinuation
-
2008
- 2008-07-28 ZA ZA200806568A patent/ZA200806568B/xx unknown
- 2008-07-29 IL IL193102A patent/IL193102A/en active IP Right Grant
-
2016
- 2016-08-17 HR HRP20161039TT patent/HRP20161039T1/hr unknown
- 2016-08-17 CY CY20161100808T patent/CY1117995T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25G | Requested change of headquarter approved |
Owner name: BIRDS PHARMA GMBH BEROLINA INNOVATIVE RESEARCH AND |
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B25A | Requested transfer of rights approved |
Owner name: IMPHAR AKTIENGESELLSCHAFT (DE) |
|
B25A | Requested transfer of rights approved |
Owner name: RATIOPHARM GMBH (DE) |
|
B25A | Requested transfer of rights approved |
Owner name: TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |