BRPI0707692B1 - uso de fosfato de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres ou de fosfato de fluoreto de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres na fabricação de composições dentais - Google Patents
uso de fosfato de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres ou de fosfato de fluoreto de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres na fabricação de composições dentais Download PDFInfo
- Publication number
- BRPI0707692B1 BRPI0707692B1 BRPI0707692-4A BRPI0707692A BRPI0707692B1 BR PI0707692 B1 BRPI0707692 B1 BR PI0707692B1 BR PI0707692 A BRPI0707692 A BR PI0707692A BR PI0707692 B1 BRPI0707692 B1 BR PI0707692B1
- Authority
- BR
- Brazil
- Prior art keywords
- fluoride
- dental
- fluoride ions
- phosphopeptide
- acp
- Prior art date
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- GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 description 1
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- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
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- 235000019271 petrolatum Nutrition 0.000 description 1
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- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- FDIKHVQUPVCJFA-UHFFFAOYSA-N phosphohistidine Chemical compound OP(=O)(O)NC(C(=O)O)CC1=CN=CN1 FDIKHVQUPVCJFA-UHFFFAOYSA-N 0.000 description 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 description 1
- DCWXELXMIBXGTH-UHFFFAOYSA-N phosphotyrosine Chemical compound OC(=O)C(N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-UHFFFAOYSA-N 0.000 description 1
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- 239000004014 plasticizer Substances 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
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- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 238000010149 post-hoc-test Methods 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- OQZCJRJRGMMSGK-UHFFFAOYSA-M potassium metaphosphate Chemical compound [K+].[O-]P(=O)=O OQZCJRJRGMMSGK-UHFFFAOYSA-M 0.000 description 1
- 229940099402 potassium metaphosphate Drugs 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
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- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
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- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
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- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
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- UGTZMIPZNRIWHX-UHFFFAOYSA-K sodium trimetaphosphate Chemical compound [Na+].[Na+].[Na+].[O-]P1(=O)OP([O-])(=O)OP([O-])(=O)O1 UGTZMIPZNRIWHX-UHFFFAOYSA-K 0.000 description 1
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- 229960005196 titanium dioxide Drugs 0.000 description 1
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- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229910052905 tridymite Inorganic materials 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- AZJYLVAUMGUUBL-UHFFFAOYSA-A u1qj22mc8e Chemical group [F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].O=[Si]=O.O=[Si]=O.O=[Si]=O.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3 AZJYLVAUMGUUBL-UHFFFAOYSA-A 0.000 description 1
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- GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
- A61K6/838—Phosphorus compounds, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
- Dental Preparations (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2006900634A AU2006900634A0 (en) | 2006-02-09 | Composition and methods for dental mineralization | |
| AU2006900634 | 2006-02-09 | ||
| AU2006903531A AU2006903531A0 (en) | 2006-06-30 | Fluoride composition and methods for dental mineralization | |
| AU2006903531 | 2006-06-30 | ||
| PCT/AU2007/000141 WO2007090242A1 (en) | 2006-02-09 | 2007-02-09 | Fluoride composition and methods for dental mineralization |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0707692A2 BRPI0707692A2 (pt) | 2011-05-10 |
| BRPI0707692A8 BRPI0707692A8 (pt) | 2018-05-15 |
| BRPI0707692B1 true BRPI0707692B1 (pt) | 2021-03-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| BRPI0707692-4A BRPI0707692B1 (pt) | 2006-02-09 | 2007-02-09 | uso de fosfato de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres ou de fosfato de fluoreto de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres na fabricação de composições dentais |
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|---|---|
| US (3) | US9668945B2 (enExample) |
| EP (2) | EP1986587B1 (enExample) |
| JP (3) | JP5231252B2 (enExample) |
| CN (1) | CN101378720B (enExample) |
| AR (1) | AR059440A1 (enExample) |
| AU (1) | AU2007214265B2 (enExample) |
| BR (1) | BRPI0707692B1 (enExample) |
| CA (1) | CA2637748C (enExample) |
| DK (1) | DK1986587T3 (enExample) |
| ES (2) | ES2698824T3 (enExample) |
| NZ (1) | NZ569785A (enExample) |
| PL (2) | PL2705826T3 (enExample) |
| RU (1) | RU2008136201A (enExample) |
| WO (1) | WO2007090242A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007214265B2 (en) | 2006-02-09 | 2012-06-14 | The University Of Melbourne | Fluoride composition and methods for dental mineralization |
| US20090324516A1 (en) * | 2008-06-27 | 2009-12-31 | Muscle Dave P | Composition and Method for Enhancing Flouride Uptake Using Bioactive Glass |
| JP2010105916A (ja) * | 2008-10-28 | 2010-05-13 | Meiji Milk Prod Co Ltd | プロセスチーズ類及び齲蝕予防方法 |
| US8741268B2 (en) * | 2009-09-10 | 2014-06-03 | Preventive Technologies, Inc. | Dental prophylactic paste |
| GB201202341D0 (en) | 2012-02-10 | 2012-03-28 | Periproducts Ltd | Multicomponent oral care compostion |
| CN102524504A (zh) * | 2012-03-13 | 2012-07-04 | 吴圣陶 | 一种护齿口香糖 |
| US9107838B2 (en) | 2012-04-25 | 2015-08-18 | Therametrics Technologies, Inc. | Fluoride varnish |
| GB201212222D0 (en) * | 2012-07-10 | 2012-08-22 | Univ Dundee | Improved apparatus and method for mineralising biological materials |
| EP2966092A4 (en) | 2013-03-08 | 2016-11-16 | Taiho Pharmaceutical Co Ltd | NOVEL PEPTIDE WITH 5 CONNECTED CTL EPITOPES |
| EA034376B1 (ru) | 2013-07-05 | 2020-01-31 | Интегра Медикал Инк. | Композиции для оздоровления полости рта |
| PL3024428T3 (pl) | 2013-07-23 | 2021-07-05 | The University Of Melbourne | Kompozycje i sposoby mineralizacji zębów |
| RU2716134C2 (ru) * | 2013-12-24 | 2020-03-06 | Де Юниверсити Оф Мельбурн | Стабилизированные композиции на основе олова (II) |
| EP2949311B1 (en) | 2014-05-30 | 2019-10-16 | Shofu Inc. | Dental composition containing ion sustained-release glass |
| RU2720242C2 (ru) * | 2014-12-24 | 2020-04-28 | Юниверсити Оф Мельбурн | Минерализующие фторсодержащие композиции |
| EP3175835A1 (en) * | 2015-12-04 | 2017-06-07 | Omya International AG | Oral care composition for remineralisation and whitening of teeth |
| EA201991935A1 (ru) | 2017-03-14 | 2020-02-14 | Де Юниверсити Оф Мельбурн | Комплексы для лечения чувствительности |
| KR102862249B1 (ko) | 2017-03-14 | 2025-09-19 | 더 유니버시티 오브 멜버른 | 치은염을 위한 치료 |
| CN108403444B (zh) * | 2018-01-26 | 2021-04-30 | 苏州派克顿科技有限公司 | 使牙釉质再矿化的组合物 |
| JP2022524856A (ja) * | 2019-03-13 | 2022-05-10 | ザ ユニバーシティー オブ メルボルン | 低石灰化病変の隠蔽 |
| CA3133097A1 (en) * | 2019-03-13 | 2020-09-17 | The University Of Melbourne | Compositions and methods for promoting mineralization |
| US12447119B2 (en) | 2019-03-18 | 2025-10-21 | Sunstar Americas, Inc. | Oral care composition |
| DE102019109150A1 (de) | 2019-04-08 | 2020-10-08 | Mühlbauer Technology Gmbh | Remineralisierendes Dentalmaterial |
| CN110074988A (zh) * | 2019-06-12 | 2019-08-02 | 四川涑爽医疗用品有限公司 | 一种抗牙本质敏感及预防龋齿的组合物及包含该组合物的口腔护理产品 |
| GB202010987D0 (en) * | 2020-07-16 | 2020-09-02 | Dentherapy Ltd | Oral care compositions and methods |
| GB202020423D0 (en) | 2020-12-22 | 2021-02-03 | Univ London Queen Mary | Composition comprising calcium phosphate and a bioactive glass comprising fluorine |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3864471A (en) | 1968-12-20 | 1975-02-04 | Colgate Palmolive Co | Stable dentifrices containing a monofluorophosphate, an insoluble metaphosphate, and calcium carbonate |
| US3966901A (en) | 1970-12-29 | 1976-06-29 | Colgate-Palmolive Company | Dentifrice preparation |
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| US20170333296A1 (en) | 2017-11-23 |
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| CN101378720B (zh) | 2012-04-25 |
| JP5231252B2 (ja) | 2013-07-10 |
| EP1986587A1 (en) | 2008-11-05 |
| US20240000671A1 (en) | 2024-01-04 |
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| DK1986587T3 (en) | 2018-12-17 |
| JP2013047271A (ja) | 2013-03-07 |
| BRPI0707692A2 (pt) | 2011-05-10 |
| EP1986587A4 (en) | 2010-05-05 |
| CN101378720A (zh) | 2009-03-04 |
| EP1986587B1 (en) | 2018-08-22 |
| US20090022672A1 (en) | 2009-01-22 |
| BRPI0707692A8 (pt) | 2018-05-15 |
| CA2637748C (en) | 2015-12-08 |
| WO2007090242A1 (en) | 2007-08-16 |
| AR059440A1 (es) | 2008-04-09 |
| RU2008136201A (ru) | 2010-03-20 |
| JP6162390B2 (ja) | 2017-07-12 |
| JP6603038B2 (ja) | 2019-11-06 |
| EP2705826B1 (en) | 2019-09-11 |
| JP2009525988A (ja) | 2009-07-16 |
| ES2755277T3 (es) | 2020-04-22 |
| US11504305B2 (en) | 2022-11-22 |
| PL1986587T3 (pl) | 2019-04-30 |
| JP2015143275A (ja) | 2015-08-06 |
| AU2007214265B2 (en) | 2012-06-14 |
| PL2705826T3 (pl) | 2020-11-02 |
| EP2705826A1 (en) | 2014-03-12 |
| AU2007214265A1 (en) | 2007-08-16 |
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