BRPI0706938A2 - compostos dicarbonìlicos com atividade antibacterial - Google Patents
compostos dicarbonìlicos com atividade antibacterial Download PDFInfo
- Publication number
- BRPI0706938A2 BRPI0706938A2 BRPI0706938-3A BRPI0706938A BRPI0706938A2 BR PI0706938 A2 BRPI0706938 A2 BR PI0706938A2 BR PI0706938 A BRPI0706938 A BR PI0706938A BR PI0706938 A2 BRPI0706938 A2 BR PI0706938A2
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- BR
- Brazil
- Prior art keywords
- formula
- alkyl
- groups
- compound
- optionally substituted
- Prior art date
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- 150000001875 compounds Chemical class 0.000 title claims description 137
- 230000000844 anti-bacterial effect Effects 0.000 title abstract description 7
- 229910052736 halogen Inorganic materials 0.000 claims abstract description 23
- 150000002367 halogens Chemical class 0.000 claims abstract description 23
- 150000003839 salts Chemical class 0.000 claims abstract description 16
- 125000001072 heteroaryl group Chemical group 0.000 claims abstract description 6
- 239000012453 solvate Substances 0.000 claims abstract description 6
- 241001465754 Metazoa Species 0.000 claims abstract description 5
- 208000035143 Bacterial infection Diseases 0.000 claims abstract description 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims abstract description 4
- 239000000203 mixture Substances 0.000 claims description 39
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims description 35
- 125000005842 heteroatom Chemical group 0.000 claims description 15
- 125000005843 halogen group Chemical group 0.000 claims description 12
- 229910052717 sulfur Inorganic materials 0.000 claims description 12
- 125000003118 aryl group Chemical group 0.000 claims description 11
- 125000002950 monocyclic group Chemical group 0.000 claims description 10
- 229920006395 saturated elastomer Polymers 0.000 claims description 10
- 229910052760 oxygen Inorganic materials 0.000 claims description 9
- 229910052757 nitrogen Inorganic materials 0.000 claims description 8
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- 125000004122 cyclic group Chemical group 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 4
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- 125000001424 substituent group Chemical group 0.000 claims description 3
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- 125000004989 dicarbonyl group Chemical group 0.000 abstract description 4
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- 238000000034 method Methods 0.000 description 35
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- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 18
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- 206010034133 Pathogen resistance Diseases 0.000 description 3
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ESP200600158 | 2006-01-19 | ||
| ES200600158 | 2006-01-19 | ||
| PCT/EP2007/050489 WO2007082910A1 (en) | 2006-01-19 | 2007-01-18 | Dicarbonylic compounds with antibacterial activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0706938A2 true BRPI0706938A2 (pt) | 2011-04-12 |
Family
ID=37781676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0706938-3A BRPI0706938A2 (pt) | 2006-01-19 | 2007-01-18 | compostos dicarbonìlicos com atividade antibacterial |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100075984A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1976837A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009523764A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20080108977A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101405277A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007206889A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0706938A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2637052A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007082910A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5291292B2 (ja) * | 2007-02-01 | 2013-09-18 | 協同油脂株式会社 | 金属加工用油剤及び金属加工方法 |
| CA2743971A1 (en) | 2008-11-20 | 2010-05-27 | Panacea Biotec Ltd. | Novel antimicrobials |
| MX2012000231A (es) | 2009-06-26 | 2012-03-07 | Panacea Biotec Ltd | Nuevos aza-biciclo-hexanos. |
| WO2011002067A1 (ja) * | 2009-07-02 | 2011-01-06 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| CN109503569B (zh) * | 2019-01-03 | 2021-01-15 | 山东大学 | 噻唑类衍生物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2180456B1 (es) * | 2001-07-20 | 2004-05-01 | Laboratorios S.A.L.V.A.T., S.A. | Isoxazoles sustituidos y su utilizacion como antibioticos. |
| WO2004014392A1 (en) * | 2002-07-29 | 2004-02-19 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
| WO2005082892A2 (en) * | 2004-02-17 | 2005-09-09 | Dr. Reddy's Laboratories Ltd. | Triazole compounds as antibacterial agents and pharmaceutical compositions containing them |
-
2007
- 2007-01-18 BR BRPI0706938-3A patent/BRPI0706938A2/pt not_active IP Right Cessation
- 2007-01-18 KR KR1020087020277A patent/KR20080108977A/ko not_active Withdrawn
- 2007-01-18 EP EP07703984A patent/EP1976837A1/en not_active Withdrawn
- 2007-01-18 AU AU2007206889A patent/AU2007206889A1/en not_active Abandoned
- 2007-01-18 US US12/161,391 patent/US20100075984A1/en not_active Abandoned
- 2007-01-18 JP JP2008550756A patent/JP2009523764A/ja not_active Withdrawn
- 2007-01-18 CN CNA2007800093540A patent/CN101405277A/zh active Pending
- 2007-01-18 WO PCT/EP2007/050489 patent/WO2007082910A1/en not_active Ceased
- 2007-01-18 CA CA002637052A patent/CA2637052A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009523764A (ja) | 2009-06-25 |
| US20100075984A1 (en) | 2010-03-25 |
| WO2007082910A1 (en) | 2007-07-26 |
| CA2637052A1 (en) | 2007-07-26 |
| KR20080108977A (ko) | 2008-12-16 |
| AU2007206889A1 (en) | 2007-07-26 |
| CN101405277A (zh) | 2009-04-08 |
| EP1976837A1 (en) | 2008-10-08 |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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