BRPI0518636B8 - kits não-radioativo liofilizado de multi-doses, e, processo para a preparação de múltiplas doses de paciente unitárias do radiofarmacêutico tetrofosmina- 99m tc" - Google Patents
kits não-radioativo liofilizado de multi-doses, e, processo para a preparação de múltiplas doses de paciente unitárias do radiofarmacêutico tetrofosmina- 99m tc"Info
- Publication number
- BRPI0518636B8 BRPI0518636B8 BRPI0518636A BRPI0518636A BRPI0518636B8 BR PI0518636 B8 BRPI0518636 B8 BR PI0518636B8 BR PI0518636 A BRPI0518636 A BR PI0518636A BR PI0518636 A BRPI0518636 A BR PI0518636A BR PI0518636 B8 BRPI0518636 B8 BR PI0518636B8
- Authority
- BR
- Brazil
- Prior art keywords
- tetrofosmin
- preparation
- radiopharmaceutical
- multiple unit
- radioactive
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Lock And Its Accessories (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Devices For Supply Of Signal Current (AREA)
- Train Traffic Observation, Control, And Security (AREA)
- Noodles (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
kits não-radioativo liofilizado e de multi-doses, processo para a preparação de múltiplas doses de paciente unitárias do radiofarmacêutico tetrofosmina ^ 99m^ tc, composição radiofarmacêutica estabilizada, e, dose de paciente unitária do radiofarmacêutico tetrofosmina ^ 99m^tc a presente invenção refere-se a composições radiofarmaeêuticas ^ 99m^tce estabilizadas da tetrofosmina de ligando, que incluem um ácido ascórbico ou radioprotetor de ascorbato, na ausência de um conservante antimicrobiano. a invenção também fornece kits liofilizados, adequados para a preparação em massa de múltiplas doses unitárias de paciente de complexos metálicos de ^ 99m^ tc-tetrofosmina. são também descritas doses unitárias de ^ 99m^tc-teftofosmina, junto com processos para preparar tais doses unitárias do frasco de massa liofihizada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0427392.6A GB0427392D0 (en) | 2004-12-15 | 2004-12-15 | Stabilised 99mTc compositions |
| PCT/GB2005/003975 WO2006064175A1 (en) | 2004-12-15 | 2005-10-14 | STABILISED 99mTC COMPOSITIONS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0518636A2 BRPI0518636A2 (pt) | 2008-12-02 |
| BRPI0518636B1 BRPI0518636B1 (pt) | 2016-12-13 |
| BRPI0518636B8 true BRPI0518636B8 (pt) | 2021-07-27 |
Family
ID=34090037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0518636A BRPI0518636B8 (pt) | 2004-12-15 | 2005-10-14 | kits não-radioativo liofilizado de multi-doses, e, processo para a preparação de múltiplas doses de paciente unitárias do radiofarmacêutico tetrofosmina- 99m tc" |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9694092B2 (pt) |
| EP (1) | EP1824525B1 (pt) |
| JP (1) | JP5064236B2 (pt) |
| KR (1) | KR101297523B1 (pt) |
| CN (2) | CN103028123A (pt) |
| AT (1) | ATE392218T1 (pt) |
| AU (1) | AU2005315503B2 (pt) |
| BR (1) | BRPI0518636B8 (pt) |
| CA (1) | CA2590620C (pt) |
| DE (1) | DE602005006157T2 (pt) |
| ES (1) | ES2306219T3 (pt) |
| GB (1) | GB0427392D0 (pt) |
| MX (1) | MX2007007223A (pt) |
| NO (1) | NO340538B1 (pt) |
| PL (1) | PL1824525T3 (pt) |
| RU (1) | RU2403067C2 (pt) |
| WO (1) | WO2006064175A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2029178B1 (en) * | 2006-06-21 | 2012-03-14 | GE Healthcare Limited | Radiopharmaceutical products |
| EP2080526A4 (en) * | 2006-11-09 | 2012-11-07 | Nihon Mediphysics Co Ltd | RADIOACTIVE DIAGNOSTIC IMAGING AGENT |
| GB0718386D0 (en) | 2007-09-21 | 2007-10-31 | Ge Healthcare As | Improved radiopharmaceutical formulation |
| RU2463075C1 (ru) * | 2011-07-01 | 2012-10-10 | Российская Федерация, От Имени Которой Выступает Министерство Образования И Науки Российской Федерации | СПОСОБ ПОЛУЧЕНИЯ МЕЧЕННОГО ТЕХНЕЦИЕМ-99m НАНОКОЛЛОИДА |
| RU2512595C1 (ru) * | 2013-01-09 | 2014-04-10 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт онкологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИ онкологии" СО РАМН) | СПОСОБ ПОЛУЧЕНИЯ РЕАГЕНТА ДЛЯ ПРИГОТОВЛЕНИЯ МЕЧЕННОГО ТЕХНЕЦИЕМ 99-m НАНОКОЛЛОИДА НА ОСНОВЕ ГАММА-ОКСИДА АЛЮМИНИЯ |
| RU2543654C1 (ru) * | 2013-11-29 | 2015-03-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский Томский политехнический университет" | СПОСОБ ПОЛУЧЕНИЯ МЕЧЕННОГО ТЕХНЕЦИЕМ-99m НАНОКОЛЛОИДА |
| EP2899195A1 (en) | 2014-01-28 | 2015-07-29 | ROTOP Pharmaka AG | Stabilized form of Tetrofosmin and its use |
| EP3183009B1 (en) * | 2015-09-30 | 2023-08-09 | Duke University | Contrast agents for magnetic resonance imaging |
| IT201600101875A1 (it) * | 2016-10-11 | 2018-04-11 | Advanced Accelerator Applications Int S A | Composizioni liofilizzate comprendenti rhAnnexin V-128, processo per la loro preparazione e loro uso per la preparazione di formulazioni contenenti 99mTc-rhAnnexin V-128 |
| CO2018001307A2 (es) | 2017-03-08 | 2018-09-20 | Jubilant Generics Ltd Formerly A Division Of Jubilant Life Sciences Ltd | Un proceso mejorado para la preparación de tetrofosmina o su sal de adición de ácido |
| US11857647B2 (en) * | 2017-11-23 | 2024-01-02 | Jubilant Draximage, Inc. | Pharmaceutical composition comprising tetrofosmin and pharmaceutically acceptable salts thereof |
| AU2019337115B2 (en) * | 2018-10-06 | 2022-03-03 | Jubilant Generics Limited | Pharmaceutical compositions of sulfur colloid and processes thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA761944B (en) | 1975-04-30 | 1977-03-30 | Procter & Gamble | Stable radiographic scanning agents |
| JPS5750928A (en) * | 1980-09-13 | 1982-03-25 | Nippon Mejifuijitsukusu Kk | Diagnostic agent for scanning bone |
| JPS5896031A (ja) * | 1981-12-03 | 1983-06-07 | Nippon Mejifuijitsukusu Kk | 放射性診断剤およびその製造用組成物 |
| GB8808414D0 (en) * | 1988-04-11 | 1988-05-11 | Amersham Int Plc | Ligands & cationic complexes thereof with technetium-99m |
| JP2860157B2 (ja) | 1990-10-31 | 1999-02-24 | 日本メジフィジックス株式会社 | 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法 |
| US5300280A (en) * | 1992-02-14 | 1994-04-05 | Mallinckrodt Medical, Inc. | Stabilized radiopharmaceutical kits |
| DE60036382D1 (de) * | 1999-06-21 | 2007-10-25 | Nihon Mediphysics Co Ltd | Verfahren zur verabreichung von arzneimitteln mit bindungsaffinität zum plasmaprotein und verwendung der zusammensetzung in dem verfahren |
| CN1184225C (zh) * | 2000-06-28 | 2005-01-12 | 北京师范大学 | 一种替曲膦季鏻盐及其制法和二步法替曲膦药盒及其应用 |
| GB0031592D0 (en) * | 2000-12-28 | 2001-02-07 | Nycomed Amersham Plc | Stabilised radiopharmaceutical compositions |
| MXPA03007595A (es) * | 2001-02-26 | 2003-12-04 | Bristol Myers Squibb Pharma Co | Analogos de acido ascorbico para metalorradiofarmaceuticos. |
-
2004
- 2004-12-15 GB GBGB0427392.6A patent/GB0427392D0/en not_active Ceased
-
2005
- 2005-10-14 MX MX2007007223A patent/MX2007007223A/es active IP Right Grant
- 2005-10-14 ES ES05794253T patent/ES2306219T3/es active Active
- 2005-10-14 RU RU2007120467/15A patent/RU2403067C2/ru active
- 2005-10-14 PL PL05794253T patent/PL1824525T3/pl unknown
- 2005-10-14 BR BRPI0518636A patent/BRPI0518636B8/pt not_active IP Right Cessation
- 2005-10-14 AU AU2005315503A patent/AU2005315503B2/en not_active Ceased
- 2005-10-14 AT AT05794253T patent/ATE392218T1/de not_active IP Right Cessation
- 2005-10-14 JP JP2007546154A patent/JP5064236B2/ja active Active
- 2005-10-14 CN CN2012104649695A patent/CN103028123A/zh active Pending
- 2005-10-14 WO PCT/GB2005/003975 patent/WO2006064175A1/en active Application Filing
- 2005-10-14 DE DE602005006157T patent/DE602005006157T2/de active Active
- 2005-10-14 CA CA2590620A patent/CA2590620C/en active Active
- 2005-10-14 CN CNA2005800430653A patent/CN101107017A/zh active Pending
- 2005-10-14 KR KR1020077013340A patent/KR101297523B1/ko active IP Right Grant
- 2005-10-14 EP EP05794253A patent/EP1824525B1/en active Active
- 2005-10-14 US US11/721,064 patent/US9694092B2/en active Active
-
2007
- 2007-06-20 NO NO20073158A patent/NO340538B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE392218T1 (de) | 2008-05-15 |
| MX2007007223A (es) | 2007-08-14 |
| WO2006064175A1 (en) | 2006-06-22 |
| JP5064236B2 (ja) | 2012-10-31 |
| CN101107017A (zh) | 2008-01-16 |
| BRPI0518636A2 (pt) | 2008-12-02 |
| JP2008524178A (ja) | 2008-07-10 |
| US20110008252A9 (en) | 2011-01-13 |
| AU2005315503B2 (en) | 2011-06-02 |
| DE602005006157T2 (de) | 2009-05-28 |
| KR101297523B1 (ko) | 2013-08-16 |
| CN103028123A (zh) | 2013-04-10 |
| KR20070089156A (ko) | 2007-08-30 |
| US9694092B2 (en) | 2017-07-04 |
| NO340538B1 (no) | 2017-05-02 |
| AU2005315503A1 (en) | 2006-06-22 |
| ES2306219T3 (es) | 2008-11-01 |
| RU2007120467A (ru) | 2009-01-27 |
| RU2403067C2 (ru) | 2010-11-10 |
| CA2590620A1 (en) | 2006-06-22 |
| EP1824525B1 (en) | 2008-04-16 |
| BRPI0518636B1 (pt) | 2016-12-13 |
| GB0427392D0 (en) | 2005-01-19 |
| EP1824525A1 (en) | 2007-08-29 |
| US20090311178A1 (en) | 2009-12-17 |
| DE602005006157D1 (de) | 2008-05-29 |
| CA2590620C (en) | 2012-12-04 |
| PL1824525T3 (pl) | 2008-11-28 |
| NO20073158L (no) | 2007-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
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| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/12/2016, OBSERVADAS AS CONDICOES LEGAIS. |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/10/2005, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 17A ANUIDADE. |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2692 DE 09-08-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |