BRPI0516790A - formulação de aceclofenac parenteral lìquida não aquosa , seus processos de preparação e métodos de tratamento - Google Patents
formulação de aceclofenac parenteral lìquida não aquosa , seus processos de preparação e métodos de tratamentoInfo
- Publication number
- BRPI0516790A BRPI0516790A BRPI0516790-6A BRPI0516790A BRPI0516790A BR PI0516790 A BRPI0516790 A BR PI0516790A BR PI0516790 A BRPI0516790 A BR PI0516790A BR PI0516790 A BRPI0516790 A BR PI0516790A
- Authority
- BR
- Brazil
- Prior art keywords
- aceclofenac
- formulation
- disclosed
- aqueous liquid
- treatment methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
FORMULAçãO DE ACECLOFENAC PARENTERAL LIQUIDA NãO AQUOSA, SEUS PROCESSOS DE PREPARAçãO E MéTODOS DE TRATAMENTO. é descrita formulação farmacêutica que pode ser fornecida por via parenteral liquida não aquosa e, mais especificamente, formulação de aceclofenac parenteral líquida não aquosa que compreende NSAID seletiva aceclofenac. Também são descritos processo de preparação de formulação de aceclofenac, forma de dosagem terapêutica e armazenagem da dose e o método de tratamento de pacientes que possuam condição ou disfunção em que é indicado tratamento com NSAID. Diclofenac formado por meio de conversão de aceclofenac é solubilizado pelo(s) solubilizante(s) não aquoso(s), que é (são) substancialmente inerte(s) com relação a essa conversão. A composição possui meios de meios de estabilização de sal de aceclofenac para inibir a precipitação de aceclofenac. As composições descritas na presente invenção são estáveis mediante armazenagem à temperatura ambiente e sob temperaturas refrigeradas. As composições descritas na presente invenção, sejam elas prontas para uso ou necessitem de diluição antes da administração, podem ser preparadas por meio de processos baratos descritos no presente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2332DE2004 | 2004-11-22 | ||
| PCT/IN2005/000339 WO2006054315A1 (en) | 2004-11-22 | 2005-10-19 | Nonaqueous liquid parenteral aceclofenac formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0516790A true BRPI0516790A (pt) | 2008-09-30 |
Family
ID=35636806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0516790-6A BRPI0516790A (pt) | 2004-11-22 | 2005-10-19 | formulação de aceclofenac parenteral lìquida não aquosa , seus processos de preparação e métodos de tratamento |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090156670A1 (pt) |
| EP (1) | EP1814517B1 (pt) |
| JP (1) | JP2008520652A (pt) |
| KR (1) | KR20070059154A (pt) |
| CN (1) | CN101060832A (pt) |
| AT (1) | ATE476962T1 (pt) |
| AU (1) | AU2005305464A1 (pt) |
| BR (1) | BRPI0516790A (pt) |
| DE (1) | DE602005022913D1 (pt) |
| ES (1) | ES2350452T3 (pt) |
| MX (1) | MX2007006106A (pt) |
| PL (1) | PL1814517T3 (pt) |
| PT (1) | PT1814517E (pt) |
| SI (1) | SI1814517T1 (pt) |
| WO (1) | WO2006054315A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5563473B2 (ja) * | 2007-11-29 | 2014-07-30 | オールトランツ インコーポレイティド | マイクロニードル孔バイアビリティを向上させるための方法及び組成物 |
| AR072777A1 (es) | 2008-03-26 | 2010-09-22 | Cephalon Inc | Formas solidas de clorhidrato de bendamustina |
| LT2528602T (lt) | 2010-01-28 | 2017-02-27 | Eagle Pharmaceuticals, Inc. | Bendamustino kompozicijos |
| US8734852B2 (en) * | 2011-11-30 | 2014-05-27 | Manu Chaudhary | Parenteral controlled release formulations of NSAID's |
| CA2867295C (en) | 2012-03-20 | 2020-08-11 | Eagle Pharmaceuticals, Inc. | Formulations of bendamustine |
| US8828979B2 (en) | 2012-03-27 | 2014-09-09 | Essential Ingredients, Inc. | Salicylic acid gel |
| US20140179740A1 (en) * | 2012-12-21 | 2014-06-26 | Mylan Inc. | Stable liquid remifentanil formulations |
| KR101598283B1 (ko) * | 2014-06-30 | 2016-02-29 | 이화여자대학교 산학협력단 | 안전성 및 효능이 증가된 월경통 완화 또는 치료용 복합제 조성물 |
| MX2019000312A (es) * | 2019-01-08 | 2019-10-09 | Federico Amezcua Amezcua | Composicion farmaceutica sinergica de aceclofenaco y betametasona para el tratamiento del dolor de afecciones reumaticas o dolor postquirurgico. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1231209A1 (en) * | 2000-12-19 | 2002-08-14 | Specialized Pharmaceutical Research Ltd. Co. | Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compound |
| KR100425226B1 (ko) * | 2001-07-03 | 2004-03-30 | 주식회사 팜트리 | 아세클로페낙을 함유하는 경제적인 경구용 제제의 조성 및제법 |
| KR20050106421A (ko) * | 2003-02-07 | 2005-11-09 | 오노 야꾸힝 고교 가부시키가이샤 | 카르복실산 화합물 |
-
2005
- 2005-10-19 MX MX2007006106A patent/MX2007006106A/es unknown
- 2005-10-19 AU AU2005305464A patent/AU2005305464A1/en not_active Abandoned
- 2005-10-19 SI SI200531152T patent/SI1814517T1/sl unknown
- 2005-10-19 PT PT05808069T patent/PT1814517E/pt unknown
- 2005-10-19 PL PL05808069T patent/PL1814517T3/pl unknown
- 2005-10-19 KR KR1020077008756A patent/KR20070059154A/ko not_active Application Discontinuation
- 2005-10-19 WO PCT/IN2005/000339 patent/WO2006054315A1/en active Search and Examination
- 2005-10-19 ES ES05808069T patent/ES2350452T3/es active Active
- 2005-10-19 EP EP05808069A patent/EP1814517B1/en active Active
- 2005-10-19 CN CNA200580039565XA patent/CN101060832A/zh active Pending
- 2005-10-19 AT AT05808069T patent/ATE476962T1/de active
- 2005-10-19 JP JP2007542517A patent/JP2008520652A/ja active Pending
- 2005-10-19 DE DE602005022913T patent/DE602005022913D1/de active Active
- 2005-10-19 US US11/719,906 patent/US20090156670A1/en not_active Abandoned
- 2005-10-19 BR BRPI0516790-6A patent/BRPI0516790A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101060832A (zh) | 2007-10-24 |
| SI1814517T1 (sl) | 2010-12-31 |
| ES2350452T3 (es) | 2011-01-24 |
| EP1814517B1 (en) | 2010-08-11 |
| AU2005305464A1 (en) | 2006-05-26 |
| ATE476962T1 (de) | 2010-08-15 |
| JP2008520652A (ja) | 2008-06-19 |
| MX2007006106A (es) | 2007-10-23 |
| US20090156670A1 (en) | 2009-06-18 |
| DE602005022913D1 (de) | 2010-09-23 |
| PL1814517T3 (pl) | 2011-02-28 |
| PT1814517E (pt) | 2010-11-03 |
| WO2006054315B1 (en) | 2006-08-17 |
| KR20070059154A (ko) | 2007-06-11 |
| WO2006054315A1 (en) | 2006-05-26 |
| EP1814517A1 (en) | 2007-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |