BRPI0516003A - composto, uso em um composto ou um éster, um sal farmaceuticamente aceitável ou um hidrato do mesmo, formulação farmacêutica, e, método para a triagem in vitro de ligandos de receptor de prostanóide seletivos - Google Patents

composto, uso em um composto ou um éster, um sal farmaceuticamente aceitável ou um hidrato do mesmo, formulação farmacêutica, e, método para a triagem in vitro de ligandos de receptor de prostanóide seletivos

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Publication number
BRPI0516003A
BRPI0516003A BRPI0516003-0A BRPI0516003A BRPI0516003A BR PI0516003 A BRPI0516003 A BR PI0516003A BR PI0516003 A BRPI0516003 A BR PI0516003A BR PI0516003 A BRPI0516003 A BR PI0516003A
Authority
BR
Brazil
Prior art keywords
compound
hydrate
ester
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
BRPI0516003-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Nian Zhou
Jasbir Singh
Mark Gurney
Georgeta Hategan
Peng Yu
David Zembower
Original Assignee
Decode Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decode Genetics Inc filed Critical Decode Genetics Inc
Publication of BRPI0516003A publication Critical patent/BRPI0516003A/pt

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    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
BRPI0516003-0A 2004-10-12 2005-06-27 composto, uso em um composto ou um éster, um sal farmaceuticamente aceitável ou um hidrato do mesmo, formulação farmacêutica, e, método para a triagem in vitro de ligandos de receptor de prostanóide seletivos BRPI0516003A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61817204P 2004-10-12 2004-10-12
PCT/US2005/023009 WO2006044000A1 (en) 2004-10-12 2005-06-27 Sulfonamide pert-substituted bicyclics for occlusive artery disease

Publications (1)

Publication Number Publication Date
BRPI0516003A true BRPI0516003A (pt) 2008-04-29

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BRPI0516003-0A BRPI0516003A (pt) 2004-10-12 2005-06-27 composto, uso em um composto ou um éster, um sal farmaceuticamente aceitável ou um hidrato do mesmo, formulação farmacêutica, e, método para a triagem in vitro de ligandos de receptor de prostanóide seletivos

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US (2) US7598397B2 (enExample)
EP (1) EP1812388B1 (enExample)
JP (1) JP2008515971A (enExample)
KR (1) KR20070091607A (enExample)
CN (1) CN101142184A (enExample)
AT (1) ATE499344T1 (enExample)
AU (1) AU2005296305A1 (enExample)
BR (1) BRPI0516003A (enExample)
CA (1) CA2583667A1 (enExample)
DE (1) DE602005026553D1 (enExample)
IL (1) IL182488A0 (enExample)
MX (1) MX2007004525A (enExample)
NO (1) NO20072288L (enExample)
NZ (1) NZ554491A (enExample)
RU (1) RU2403240C2 (enExample)
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DE602005026553D1 (de) * 2004-10-12 2011-04-07 Decode Genetics Ehf Peri-substituierte bicyclische sulfonamide gegen arterielle verschlusskrankheit
CN101076531A (zh) * 2004-10-12 2007-11-21 解码遗传学公司 用于阻塞性血管疾病的羧酸迫位取代的双环化合物
TW200740435A (en) * 2005-08-10 2007-11-01 Takeda Pharmaceuticals Co Therapeutic agent for diabetes
US20080125477A1 (en) * 2006-05-16 2008-05-29 Decode Genetics, Ehf. 7-(acryloyl) indole compositions and methods of making and using same
CA2652152A1 (en) * 2006-05-16 2007-11-29 Decode Genetics Ehf Process for preparing 7-(acryloyl)indoles
WO2007143825A1 (en) * 2006-06-12 2007-12-21 Merck Frosst Canada Ltd. Indoline amide derivatives as ep4 receptor ligands
WO2008127274A2 (en) * 2006-09-22 2008-10-23 Ptc Therapeutics, Inc. Heterocyclic inhibitors of bacterial peptidyl trna hydrolase and uses thereof
TW200843739A (en) * 2007-03-30 2008-11-16 Shionogi & Co Novel pyrrolinone derivative and composition containing the same
EP2219648A4 (en) * 2007-11-09 2010-11-03 Cenomed Biosciences Llc TREATMENT OF POSTRAUMATIC STRESS WITH TETRAHYDROINDOLONE ARYLPIPERAZINE COMPOUNDS
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JP2008515971A (ja) 2008-05-15
IL182488A0 (en) 2007-09-20
WO2006044000A1 (en) 2006-04-27
ATE499344T1 (de) 2011-03-15
US20090291948A1 (en) 2009-11-26
CA2583667A1 (en) 2006-04-27
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NO20072288L (no) 2007-06-25
RU2007115410A (ru) 2008-11-10
US20060079520A1 (en) 2006-04-13
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