BRPI0513741A - processo de melhoria da imunogeneicidade de um imunogene, antìgeno ou hapteno, complexo imunogênico, ácido nucleico e utilização de um complexo imunogênico - Google Patents
processo de melhoria da imunogeneicidade de um imunogene, antìgeno ou hapteno, complexo imunogênico, ácido nucleico e utilização de um complexo imunogênicoInfo
- Publication number
- BRPI0513741A BRPI0513741A BRPI0513741-1A BRPI0513741A BRPI0513741A BR PI0513741 A BRPI0513741 A BR PI0513741A BR PI0513741 A BRPI0513741 A BR PI0513741A BR PI0513741 A BRPI0513741 A BR PI0513741A
- Authority
- BR
- Brazil
- Prior art keywords
- immunogenic complex
- immunogenicity
- antigen
- peptide
- immunogen
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 7
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 230000005847 immunogenicity Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 230000002708 enhancing effect Effects 0.000 abstract 2
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 101710120037 Toxin CcdB Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCESSO DE MELHORIA DA IMUNOGENEICIDADE DE UM IMUNOGENE, ANTìGENO OU HAPTENO, COMPLEXO IMUNOGêNICO, áCIDO NUCLEICO E UTILIZAçãO DE UM COMPLEXO IMUNOGêNICO A presente invenção refere-se a um processo permitindo melhorar a imunogenicidade de um imunogene, antígeno ou hapteno, por copulação com um peptídeo suporte de tamanho pequeno. Mais particularmente, a presente invenção refere-se a um processo de preparação de um complexo imunogênico assim com os complexos susceptíveis de serem obtidos por um tal processo, e a utilização de tais complexos a título de medicamento para aumentar a imunogenicidade de um imunogene. A invenção compreende notadamente um peptídeo suporte copulado com um peptídeo proveniente da proteína G do vírus respiratório sincicial (VRS) e sua utilização a título vacinal para o tratamento de infecções respiratórias ligadas ao VRS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0408175A FR2873378A1 (fr) | 2004-07-23 | 2004-07-23 | Complexes immunogenes, leur procede de preparation et leur utilisation dans des compositions pharmaceutiques |
| PCT/FR2005/001913 WO2006018527A1 (fr) | 2004-07-23 | 2005-07-25 | Complexes immunogenes, leur procede de preparation et leur utilisation dans des compositions pharmaceutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0513741A true BRPI0513741A (pt) | 2008-05-13 |
Family
ID=34947471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0513741-1A BRPI0513741A (pt) | 2004-07-23 | 2005-07-25 | processo de melhoria da imunogeneicidade de um imunogene, antìgeno ou hapteno, complexo imunogênico, ácido nucleico e utilização de um complexo imunogênico |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080300382A1 (pt) |
| EP (1) | EP1776379A1 (pt) |
| JP (1) | JP2008512986A (pt) |
| KR (1) | KR20070058457A (pt) |
| CN (1) | CN1989150A (pt) |
| AU (1) | AU2005273779A1 (pt) |
| BR (1) | BRPI0513741A (pt) |
| CA (1) | CA2574340A1 (pt) |
| FR (1) | FR2873378A1 (pt) |
| IL (1) | IL180900A0 (pt) |
| MX (1) | MX2007000887A (pt) |
| NO (1) | NO20071030L (pt) |
| RU (1) | RU2007106900A (pt) |
| WO (1) | WO2006018527A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA021393B1 (ru) | 2007-12-24 | 2015-06-30 | Глаксосмитклайн Байолоджикалс С.А. | Рекомбинантные антигены rsv |
| BRPI0915960A2 (pt) * | 2008-07-18 | 2019-09-24 | Id Biomedical Corp | antígenos de polipeptídeos do vírus sincicial respiratório qimérico |
| JP5796011B2 (ja) | 2009-06-24 | 2015-10-21 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| SI2445526T1 (sl) | 2009-06-24 | 2016-08-31 | Glaxosmithkline Biologicals S.A. | Rekombinantni RSV antigeni |
| ES2918381T3 (es) | 2009-07-15 | 2022-07-15 | Glaxosmithkline Biologicals Sa | Composiciones de proteína F de VRS y métodos para producir las mismas |
| KR20120081587A (ko) | 2009-09-10 | 2012-07-19 | 노파르티스 아게 | 기도 질병에 대한 조합 백신 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2726471B1 (fr) * | 1994-11-07 | 1997-01-31 | Pf Medicament | Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins |
| FR2798292A1 (fr) * | 1999-09-09 | 2001-03-16 | Pf Medicament | Utilisation d'ammoniums quaternaires aliphatiques pour induire une reponse mixte th1/th2 |
| FR2827606A1 (fr) * | 2001-07-20 | 2003-01-24 | Pf Medicament | Nouveaux derives d'anatoxines diphteriques et leur utilisation comme porteur |
-
2004
- 2004-07-23 FR FR0408175A patent/FR2873378A1/fr not_active Withdrawn
-
2005
- 2005-07-25 WO PCT/FR2005/001913 patent/WO2006018527A1/fr active Application Filing
- 2005-07-25 US US11/658,173 patent/US20080300382A1/en not_active Abandoned
- 2005-07-25 CN CNA2005800243233A patent/CN1989150A/zh active Pending
- 2005-07-25 KR KR1020077004395A patent/KR20070058457A/ko not_active Application Discontinuation
- 2005-07-25 EP EP05793088A patent/EP1776379A1/fr not_active Withdrawn
- 2005-07-25 JP JP2007521992A patent/JP2008512986A/ja not_active Abandoned
- 2005-07-25 RU RU2007106900/13A patent/RU2007106900A/ru not_active Application Discontinuation
- 2005-07-25 CA CA002574340A patent/CA2574340A1/fr not_active Abandoned
- 2005-07-25 MX MX2007000887A patent/MX2007000887A/es unknown
- 2005-07-25 BR BRPI0513741-1A patent/BRPI0513741A/pt not_active IP Right Cessation
- 2005-07-25 AU AU2005273779A patent/AU2005273779A1/en not_active Abandoned
-
2007
- 2007-01-23 IL IL180900A patent/IL180900A0/en unknown
- 2007-02-23 NO NO20071030A patent/NO20071030L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL180900A0 (en) | 2007-07-04 |
| US20080300382A1 (en) | 2008-12-04 |
| RU2007106900A (ru) | 2008-09-10 |
| NO20071030L (no) | 2007-04-23 |
| MX2007000887A (es) | 2007-03-12 |
| JP2008512986A (ja) | 2008-05-01 |
| WO2006018527A1 (fr) | 2006-02-23 |
| CA2574340A1 (fr) | 2006-02-23 |
| KR20070058457A (ko) | 2007-06-08 |
| AU2005273779A1 (en) | 2006-02-23 |
| CN1989150A (zh) | 2007-06-27 |
| EP1776379A1 (fr) | 2007-04-25 |
| FR2873378A1 (fr) | 2006-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |