BRPI0513199A - compostos orgánicos - Google Patents

compostos orgánicos

Info

Publication number
BRPI0513199A
BRPI0513199A BRPI0513199-5A BRPI0513199A BRPI0513199A BR PI0513199 A BRPI0513199 A BR PI0513199A BR PI0513199 A BRPI0513199 A BR PI0513199A BR PI0513199 A BRPI0513199 A BR PI0513199A
Authority
BR
Brazil
Prior art keywords
organic compounds
compounds
medicaments
general formula
preparation
Prior art date
Application number
BRPI0513199-5A
Other languages
English (en)
Inventor
Peter Herold
Robert Mah
Stefan Stutz
Aleksandar Stojanovic
Vicenzo Tschinke
Nathalie Jotterand
Dirk Behnke
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Publication of BRPI0513199A publication Critical patent/BRPI0513199A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

COMPOSTOS ORGáNICOS. A presente invenção refere-se a novas piperidinas substituídas da fórmula geral em que R¬ 1¬, R¬ 2¬, R¬ 3¬, R¬ 4¬, W, X, Z, m e n são cada como definidos em detalhes na descrição, a um processo para sua preparação e ao uso desses compostos como medicamentos, em particular como inibidores de renina. Novo quadro reivindicatório (total de 10 reivindicações), incorporando as emendas às reivindicações, conforme relatório de exame preliminar.
BRPI0513199-5A 2004-07-09 2005-07-11 compostos orgánicos BRPI0513199A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH11582004 2004-07-09
PCT/EP2005/053306 WO2006005741A2 (en) 2004-07-09 2005-07-11 Piperdine derivatives as renin inhibitors

Publications (1)

Publication Number Publication Date
BRPI0513199A true BRPI0513199A (pt) 2008-04-29

Family

ID=35448323

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513199-5A BRPI0513199A (pt) 2004-07-09 2005-07-11 compostos orgánicos

Country Status (15)

Country Link
US (1) US20080076766A1 (pt)
EP (1) EP1776359B1 (pt)
JP (1) JP4842262B2 (pt)
CN (1) CN101014594A (pt)
AR (1) AR053406A1 (pt)
AT (1) ATE521607T1 (pt)
BR (1) BRPI0513199A (pt)
CA (1) CA2570920A1 (pt)
ES (1) ES2372502T3 (pt)
HK (1) HK1104037A1 (pt)
IL (1) IL180242A0 (pt)
PL (1) PL1776359T3 (pt)
PT (1) PT1776359E (pt)
TW (1) TW200613274A (pt)
WO (1) WO2006005741A2 (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8138340B2 (en) 2004-08-25 2012-03-20 Actelion Pharmaceuticals Ltd. Bicyclononene derivatives
GB0428526D0 (en) 2004-12-30 2005-02-09 Novartis Ag Organic compounds
TW200722424A (en) 2005-03-31 2007-06-16 Speedel Experimenta Ag Substituted piperidines
EP1707202A1 (de) * 2005-03-31 2006-10-04 Speedel Experimenta AG Organische Verbindungen
BRPI0609534A2 (pt) * 2005-03-31 2010-04-13 Speedel Experimenta Ag piperidinas 3,4,5-substituìdas
GB0508992D0 (en) * 2005-05-03 2005-06-08 Novartis Ag Organic compounds
GB0510810D0 (en) * 2005-05-26 2005-06-29 Novartis Ag Organic compounds
US7799805B2 (en) 2005-05-27 2010-09-21 Actelion Pharmaceuticals Ltd. Piperidine carboxylic acid amide derivatives
GB0514203D0 (en) 2005-07-11 2005-08-17 Novartis Ag Organic compounds
ES2430139T3 (es) 2005-12-30 2013-11-19 Novartis Ag Compuestos de piperidina 3,5-sustituido como inhibidores de renina
EP1816122A3 (en) * 2006-01-19 2007-09-19 Speedel Experimenta AG 3,4,5-substituted piperidines as therapeutic compounds
TW200804359A (en) * 2006-01-19 2008-01-16 Speedel Experimenta Ag Substituted 4-phenylpiperidines
TW200821303A (en) * 2006-08-08 2008-05-16 Speedel Experimenta Ag Organic compounds
EP1911758A1 (en) * 2006-10-04 2008-04-16 Speedel Experimenta AG Phenyl piperidine derivatives for use as renin inhibitors
EP1908761A1 (en) * 2006-10-04 2008-04-09 Speedel Experimenta AG Organic compounds
WO2008074450A2 (en) * 2006-12-20 2008-06-26 Nicox S.A. Non-peptidic renin inhibitors nitroderivatives
TWI452044B (zh) * 2007-06-15 2014-09-11 Mitsubishi Tanabe Pharma Corp 嗎啉衍生物
ES2541107T3 (es) 2007-06-25 2015-07-16 Novartis Ag Derivados de N5-(2-etoxietil)-N3-(2-piridinil)-3,5-piperidindicarboxamida para su uso como inhibidores de renina
AR069005A1 (es) * 2007-10-25 2009-12-23 Speedel Experimenta Ag Piperidinas 4,4-disustituidas
TW200932241A (en) 2007-12-05 2009-08-01 Speedel Experimenta Ag Organic compounds
WO2009098275A1 (en) * 2008-02-08 2009-08-13 Novartis Ag Substituted piperidines as renin inhibitors
KR20100131427A (ko) * 2008-02-08 2010-12-15 노파르티스 아게 레닌 억제제로서의 치환된 피페리딘
WO2009106599A2 (en) * 2008-02-29 2009-09-03 Novartis Ag Substituted piperidines as therapeutic compounds
WO2009127251A1 (en) * 2008-04-16 2009-10-22 Novartis Ag Combinations comprising a renin inhibitor
WO2009135299A1 (en) * 2008-05-05 2009-11-12 Merck Frosst Canada Ltd. 3, 4 - substituted piperidine derivatives as renin inhibitors
EA201301040A1 (ru) 2008-06-19 2014-01-30 Такеда Фармасьютикал Компани Лимитед Гетероциклическое соединение и его применение
EP2163245A1 (en) 2008-09-10 2010-03-17 Novartis Ag Renin inhibitors for the treatment of psoriasis
EP2336105B9 (en) 2008-09-19 2014-09-17 Takeda Pharmaceutical Company Limited Nitrogen-containing heterocyclic compound and use of same
CA2756780A1 (en) * 2009-04-03 2010-10-07 Merck Sharp & Dohme Corp. Renin inhibitors
EP2384746A3 (en) 2010-05-05 2012-03-07 Sanovel Ilac Sanayi ve Ticaret A.S. Dual release oral tablet compositions of dexlansoprazole
EP2384745A3 (en) 2010-05-05 2012-01-18 Sanovel Ilac Sanayi ve Ticaret A.S. Modified release pharmaceutical compositions of dexlansoprazole
US8563035B2 (en) 2010-05-05 2013-10-22 Sanovel Ilac Sanayi Ve Ticaret Anomin Sirketi Oral tablet compositions of dexlansoprazole

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ315677A (en) * 1995-09-07 2000-02-28 F 4-(oxyalkoxyphenyl)-3-oxy-piperidines for treating heart and kidney insufficiency
US6197959B1 (en) * 1999-04-27 2001-03-06 Hoffmann-La Roche Inc. Piperidine derivatives
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
EP1389194A2 (en) * 2001-04-27 2004-02-18 Vertex Pharmaceuticals Incorporated Inhibitors of bace
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors

Also Published As

Publication number Publication date
PT1776359E (pt) 2011-12-15
WO2006005741A3 (en) 2006-07-06
WO2006005741A2 (en) 2006-01-19
IL180242A0 (en) 2007-07-04
CA2570920A1 (en) 2006-01-19
EP1776359A2 (en) 2007-04-25
JP4842262B2 (ja) 2011-12-21
TW200613274A (en) 2006-05-01
CN101014594A (zh) 2007-08-08
US20080076766A1 (en) 2008-03-27
EP1776359B1 (en) 2011-08-24
HK1104037A1 (en) 2008-01-04
JP2008505871A (ja) 2008-02-28
ES2372502T3 (es) 2012-01-20
AR053406A1 (es) 2007-05-09
ATE521607T1 (de) 2011-09-15
PL1776359T3 (pl) 2012-01-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 8A, 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.