BRPI0511765A - métodos de tratar cáncer de mama, de pulmão, e colo-retal em um mamìfero - Google Patents
métodos de tratar cáncer de mama, de pulmão, e colo-retal em um mamìferoInfo
- Publication number
- BRPI0511765A BRPI0511765A BRPI0511765-8A BRPI0511765A BRPI0511765A BR PI0511765 A BRPI0511765 A BR PI0511765A BR PI0511765 A BRPI0511765 A BR PI0511765A BR PI0511765 A BRPI0511765 A BR PI0511765A
- Authority
- BR
- Brazil
- Prior art keywords
- mammal
- lung
- methods
- colorectal cancer
- treating breast
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
MéTODOS DE TRATAR CáNCER DE MAMA, DE PULMãO, E COLO-RETAL EM UM MAMìFERO A presente invenção refere-se a um método de tratamento de câncer em um mamífero pela administração de 4-quinazolinaminas e pelo menos um composto antineoplásico adicional. Em particular, o método refere-se a um método de tratamento de cânceres pela administração de N-{3-cloro-4-¢(3-fluoro-benzil)-óxi!-fenil}-6-¢5-({¢2-(metano-sulfonil)-etil! -amino}-metil)-2-furil!-4-quinazolinamina e de seus sais e solvatos em combinação com pelo menos um composto antineoplásico adicional.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57733704P | 2004-06-04 | 2004-06-04 | |
| PCT/US2005/019568 WO2005120512A2 (en) | 2004-06-04 | 2005-06-03 | Cancer treatment method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0511765A true BRPI0511765A (pt) | 2008-01-08 |
Family
ID=35503649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0511765-8A BRPI0511765A (pt) | 2004-06-04 | 2005-06-03 | métodos de tratar cáncer de mama, de pulmão, e colo-retal em um mamìfero |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090317383A1 (pt) |
| EP (1) | EP1765344A4 (pt) |
| JP (1) | JP2008501708A (pt) |
| KR (1) | KR20070034536A (pt) |
| CN (2) | CN1984656B (pt) |
| AU (2) | AU2005251769B2 (pt) |
| BR (1) | BRPI0511765A (pt) |
| CA (1) | CA2569139A1 (pt) |
| IL (1) | IL179323A0 (pt) |
| MA (1) | MA28901B1 (pt) |
| MX (1) | MXPA06013952A (pt) |
| NO (1) | NO20066079L (pt) |
| RU (2) | RU2361589C2 (pt) |
| WO (1) | WO2005120512A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2426007T3 (es) * | 2004-12-17 | 2013-10-18 | Smithkline Beecham (Cork) Limited | Método para el tratamiento del cáncer |
| WO2007143483A2 (en) * | 2006-06-01 | 2007-12-13 | Smithkline Beecham Corporation | Combination of pazopanib and lapatinib for treating cancer |
| CN101594870A (zh) * | 2006-08-22 | 2009-12-02 | 康塞特医药品有限公司 | 4-氨基喹唑啉衍生物及其使用方法 |
| MX2009003660A (es) | 2006-10-06 | 2009-04-22 | Takeda Pharmaceutical | Farmaco combinado. |
| EP2088862A4 (en) * | 2006-11-28 | 2009-12-02 | Smithkline Beecham Cork Ltd | METHOD OF TREATING CANCER |
| CA2675366A1 (en) * | 2007-01-18 | 2008-07-24 | University Of Southern California | Gene polymorphisms predictive for dual tki therapy |
| US20110003805A1 (en) | 2008-03-03 | 2011-01-06 | Takeda Pharmaceutical Company Limited | Concomitant drug |
| US8252805B2 (en) | 2008-05-07 | 2012-08-28 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib ditosylate and processes for preparation thereof |
| EP3620154A1 (en) | 2009-02-06 | 2020-03-11 | University Of Southern California | Therapeutic compositions comprising monoterpenes |
| US8568968B2 (en) | 2009-04-13 | 2013-10-29 | University Of Southern California | EGFR polymorphisms predict gender-related treatment |
| US20140302050A1 (en) * | 2011-11-09 | 2014-10-09 | Albert Einstein College Of Medicine Of Yeshiva University | Targeting an amphiregulin-derived cell surface neo-epitope |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786344A (en) * | 1994-07-05 | 1998-07-28 | Arch Development Corporation | Camptothecin drug combinations and methods with reduced side effects |
| RS49779B (sr) * | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze |
| ES2273841T3 (es) * | 2000-02-28 | 2007-05-16 | Pfizer Enterprises Sarl | Combinacion sinergica para el tratamiento de cancer colorrectal. |
| KR100815681B1 (ko) * | 2000-06-30 | 2008-03-20 | 글락소 그룹 리미티드 | 퀴나졸린 디토실레이트 염 화합물 |
| ES2236481T3 (es) * | 2001-01-16 | 2005-07-16 | Glaxo Group Limited | Combinacion farmaceutica que contiene una 4-quinazolinamina y paclitaxel, carboplatino o vinorelbina para el tratamiento de cancer. |
| PA8578001A1 (es) * | 2002-08-07 | 2004-05-07 | Warner Lambert Co | Combinaciones terapeuticas de inhibidores de quinasa de erb b y terapias antineoplasicas |
| US20060204966A1 (en) * | 2003-08-01 | 2006-09-14 | Spector Neil L | Treatment of cancers expressing p95 erbb2 |
| US8211030B2 (en) * | 2009-03-26 | 2012-07-03 | The General Electric Company | NIBP target inflation pressure automation using derived SPO2 signals |
-
2005
- 2005-06-03 JP JP2007515618A patent/JP2008501708A/ja active Pending
- 2005-06-03 CN CN200580018262XA patent/CN1984656B/zh active Active
- 2005-06-03 US US11/569,878 patent/US20090317383A1/en not_active Abandoned
- 2005-06-03 MX MXPA06013952A patent/MXPA06013952A/es active IP Right Grant
- 2005-06-03 AU AU2005251769A patent/AU2005251769B2/en active Active
- 2005-06-03 EP EP05758577A patent/EP1765344A4/en not_active Withdrawn
- 2005-06-03 KR KR1020067027698A patent/KR20070034536A/ko not_active Application Discontinuation
- 2005-06-03 RU RU2006142418/14A patent/RU2361589C2/ru not_active IP Right Cessation
- 2005-06-03 BR BRPI0511765-8A patent/BRPI0511765A/pt not_active IP Right Cessation
- 2005-06-03 WO PCT/US2005/019568 patent/WO2005120512A2/en active Application Filing
- 2005-06-03 CN CNA2009101415491A patent/CN101564535A/zh active Pending
- 2005-06-03 CA CA002569139A patent/CA2569139A1/en not_active Abandoned
-
2006
- 2006-11-16 IL IL179323A patent/IL179323A0/en unknown
- 2006-12-25 MA MA29554A patent/MA28901B1/fr unknown
- 2006-12-29 NO NO20066079A patent/NO20066079L/no not_active Application Discontinuation
-
2008
- 2008-10-09 AU AU2008229859A patent/AU2008229859A1/en not_active Abandoned
- 2008-12-19 RU RU2008150250/14A patent/RU2008150250A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005251769A1 (en) | 2005-12-22 |
| IL179323A0 (en) | 2007-05-15 |
| EP1765344A4 (en) | 2009-12-02 |
| WO2005120512A2 (en) | 2005-12-22 |
| JP2008501708A (ja) | 2008-01-24 |
| AU2005251769B2 (en) | 2008-10-02 |
| RU2006142418A (ru) | 2008-07-20 |
| RU2361589C2 (ru) | 2009-07-20 |
| MA28901B1 (fr) | 2007-10-01 |
| CN1984656A (zh) | 2007-06-20 |
| WO2005120512A3 (en) | 2006-04-27 |
| US20090317383A1 (en) | 2009-12-24 |
| KR20070034536A (ko) | 2007-03-28 |
| MXPA06013952A (es) | 2007-02-08 |
| RU2008150250A (ru) | 2010-06-27 |
| AU2008229859A1 (en) | 2008-10-30 |
| NO20066079L (no) | 2007-01-12 |
| EP1765344A2 (en) | 2007-03-28 |
| CA2569139A1 (en) | 2005-12-22 |
| CN101564535A (zh) | 2009-10-28 |
| CN1984656B (zh) | 2010-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: LEO OSPREY LIMITED (GB) |
|
| B25A | Requested transfer of rights approved |
Owner name: NOVARTIS AG (CH) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 14A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2517 DE 02-04-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |