CY1112570T1 - Θεραπεια καρκινων με μετασταση - Google Patents

Θεραπεια καρκινων με μετασταση

Info

Publication number
CY1112570T1
CY1112570T1 CY20111101216T CY111101216T CY1112570T1 CY 1112570 T1 CY1112570 T1 CY 1112570T1 CY 20111101216 T CY20111101216 T CY 20111101216T CY 111101216 T CY111101216 T CY 111101216T CY 1112570 T1 CY1112570 T1 CY 1112570T1
Authority
CY
Cyprus
Prior art keywords
cancer treatment
compound
transitional cancer
tautomer
pharmaceutically acceptable
Prior art date
Application number
CY20111101216T
Other languages
English (en)
Inventor
De Menezes Daniel Lopes
Carla Heise
Xiaοhua Xin
Original Assignee
Novartis Vaccines And Diagnostics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36741085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112570(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines And Diagnostics, Inc. filed Critical Novartis Vaccines And Diagnostics, Inc.
Publication of CY1112570T1 publication Critical patent/CY1112570T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Μέθοδοι για τη θεραπεία του μεταστατικού καρκίνου όπως όγκοι με μετάσταση περιλαμβάνουν τη χορήγηση σε ένα υποκείμενο που το έχει ανάγκη, μιας αποτελεσματικής ποσότητας μιας ένωσης της Δομής I, ενός ταυτομερούς της ένωσης, ενός φαρμακευτικώς αποδεκτού άλατος της ένωσης, ενός φαρμακευτικώς αποδεκτού άλατος του ταυτομερούς, ή ενός μείγματος αυτών. Η ένωση, το ταυτομερές, το άλας της ένωσης, το άλας του ταυτομερούς, ή μείγμα αυτών μπορούν να χρησιμοποιηθούν για την παρασκευή φαρμάκων για τη θεραπεία του μεταστατικού καρκίνου. Η μεταβλητή Α έχει τις τιμές που ορίζονται στο παρόν.
CY20111101216T 2005-01-27 2011-12-06 Θεραπεια καρκινων με μετασταση CY1112570T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64756805P 2005-01-27 2005-01-27
US66924505P 2005-04-06 2005-04-06
US72205305P 2005-09-29 2005-09-29
EP06733986A EP1845990B1 (en) 2005-01-27 2006-01-27 Treatment of metastasized tumors

Publications (1)

Publication Number Publication Date
CY1112570T1 true CY1112570T1 (el) 2016-02-10

Family

ID=36741085

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111101216T CY1112570T1 (el) 2005-01-27 2011-12-06 Θεραπεια καρκινων με μετασταση

Country Status (23)

Country Link
US (2) US20060183750A1 (el)
EP (2) EP2301546B1 (el)
JP (2) JP5371246B2 (el)
KR (1) KR101387985B1 (el)
CN (1) CN103893181A (el)
AT (1) ATE526025T1 (el)
AU (1) AU2006208012B2 (el)
BR (1) BRPI0607285A2 (el)
CA (1) CA2596084A1 (el)
CY (1) CY1112570T1 (el)
DK (1) DK1845990T3 (el)
ES (2) ES2374570T3 (el)
HK (1) HK1155664A1 (el)
IL (1) IL184866A0 (el)
MA (1) MA29266B1 (el)
MX (1) MX2007009099A (el)
NO (1) NO20074360L (el)
PL (2) PL1845990T3 (el)
PT (2) PT1845990E (el)
SG (1) SG173317A1 (el)
SI (1) SI2301546T1 (el)
TN (1) TNSN07294A1 (el)
WO (1) WO2006081445A2 (el)

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ES2440799T3 (es) * 2005-05-13 2014-01-30 Novartis Ag Métodos para tratar cáncer resistente a los fármacos
RU2425041C2 (ru) * 2005-05-23 2011-07-27 Новартис Аг Кристаллические и другие формы солей, образованных из молочной кислоты и 4-амино-5-фтор-3-[6-(4-метилпиперазин-1-ил)-1н-бензимидазол-2-ил]-1н-хинолин-2-она
AR070924A1 (es) * 2008-03-19 2010-05-12 Novartis Ag Formas cristalinas y dos formas solvatadas de sales del acido lactico de 4- amino -5- fluoro-3-(5-(4-metilpiperazin-1-il ) -1h- bencimidazol-2-il) quinolin -2-(1h) - ona
WO2010135534A2 (en) * 2009-05-20 2010-11-25 Children's Medical Center Corporation Compositions for the treatment of metastatic cancer and methods of use thereof
CA2793779A1 (en) 2010-04-16 2011-10-20 Novartis Ag Organic compound for use in the treatment of liver cancer
KR20140023358A (ko) * 2011-05-19 2014-02-26 노파르티스 아게 선양 낭성 암종의 치료에 사용하기 위한 4-아미노-5-플루오로-3-[6-(4-메틸피페라진-1-일)-1h-벤즈이미다졸-2-일]-1h-퀴놀린-2-온
CA2861377A1 (en) * 2012-01-31 2013-08-08 Novartis Ag Combination of a rtk inhibitor with an anti - estrogen and use thereof for the treatment of cancer
JP6990228B2 (ja) * 2016-07-14 2022-01-13 ブリストル－マイヤーズ スクイブ カンパニー 二環式ヘテロアリール置換の化合物

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Also Published As

Publication number Publication date
PL2301546T3 (pl) 2015-03-31
WO2006081445A2 (en) 2006-08-03
EP1845990A4 (en) 2008-04-30
BRPI0607285A2 (pt) 2009-08-25
SG173317A1 (en) 2011-08-29
ATE526025T1 (de) 2011-10-15
EP2301546B1 (en) 2014-09-10
US20100173873A1 (en) 2010-07-08
KR20070118596A (ko) 2007-12-17
EP1845990A2 (en) 2007-10-24
ES2525670T3 (es) 2014-12-29
JP2008528617A (ja) 2008-07-31
PL1845990T3 (pl) 2012-02-29
KR101387985B1 (ko) 2014-04-25
SI2301546T1 (sl) 2015-01-30
JP5371246B2 (ja) 2013-12-18
PT2301546E (pt) 2014-12-18
WO2006081445A3 (en) 2007-01-11
ES2374570T3 (es) 2012-02-17
AU2006208012A1 (en) 2006-08-03
EP1845990B1 (en) 2011-09-28
MX2007009099A (es) 2007-09-13
IL184866A0 (en) 2007-12-03
NO20074360L (no) 2007-10-25
JP2013177464A (ja) 2013-09-09
TNSN07294A1 (en) 2008-12-31
CN103893181A (zh) 2014-07-02
CA2596084A1 (en) 2006-08-03
AU2006208012B2 (en) 2011-08-04
HK1155664A1 (en) 2012-05-25
US20060183750A1 (en) 2006-08-17
EP2301546A1 (en) 2011-03-30
DK1845990T3 (da) 2012-01-02
PT1845990E (pt) 2011-12-23
MA29266B1 (fr) 2008-02-01

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