BRPI0511454A - imunoensaio para plasmodium falciparum e instrumentos de ensaio usados - Google Patents
imunoensaio para plasmodium falciparum e instrumentos de ensaio usadosInfo
- Publication number
- BRPI0511454A BRPI0511454A BRPI0511454-3A BRPI0511454A BRPI0511454A BR PI0511454 A BRPI0511454 A BR PI0511454A BR PI0511454 A BRPI0511454 A BR PI0511454A BR PI0511454 A BRPI0511454 A BR PI0511454A
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- plasmodium falciparum
- immunoassay
- antigen
- solid phase
- Prior art date
Links
- 241000223960 Plasmodium falciparum Species 0.000 title abstract 4
- 238000003018 immunoassay Methods 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 201000004792 malaria Diseases 0.000 abstract 3
- 239000003550 marker Substances 0.000 abstract 3
- 239000007790 solid phase Substances 0.000 abstract 3
- 210000004369 blood Anatomy 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 229940127121 immunoconjugate Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
- G01N2333/445—Plasmodium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
IMUNOENSAIO PARA PLASMODIUM FALCIPARUM E INSTRUMENTOS DE ENSAIO USADOS São divulgados um imunoensaio do Plasmodium falciparum para determinar a presença/ausência via marcador específico e/ou seu anticorpo em conjugados ligados a um antígeno específico e/ou anticorpo presente em uma amostra, compreendendo a imobilização do antígeno e anticorpo específicos do Plasmodium falciparum em uma fase sólida, adicionando uma amostra obtida de um sujeito de interesse à fase sólida de forma a induzir reação antígeno-anticorpo específica, adicionando um conjugado do antígeno e um marcador e um conjugado do anticorpo e um marcador, preparados separadamente, a fim de induzir a ligação de pelo menos um dos conjugados; e um instrumento de ensaio compreendendo a fase sólida e os conjugados mencionados acima. A presente invenção pode causar a detecção de antígenos e/ou anticorpos em pacientes com manifestação de sintomas da malária assim como portadores da malária e também pode ser eficientemente empregada em amostras nos estágios iniciais da infecção da malária que é difícil de detectar via técnicas convencionais. Além disso, devido a capacidade de utilizar soro e plasma sanguíneo ao invés do sangue total, a presente invenção é bem adequada para exames em larga escala como triagem sangüínea.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020040049985A KR101035111B1 (ko) | 2004-06-30 | 2004-06-30 | 말라리아 플라스모듐 팔시파룸의 면역학적 측정방법 및이에 사용되는 측정 수단 |
PCT/KR2005/002010 WO2006004332A1 (en) | 2004-06-30 | 2005-06-28 | Immunoassay for plasmodium falciparum and assay device used therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0511454A true BRPI0511454A (pt) | 2007-12-26 |
Family
ID=35783098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0511454-3A BRPI0511454A (pt) | 2004-06-30 | 2005-06-28 | imunoensaio para plasmodium falciparum e instrumentos de ensaio usados |
Country Status (7)
Country | Link |
---|---|
US (1) | US20090197347A1 (pt) |
KR (1) | KR101035111B1 (pt) |
CN (1) | CN101014858A (pt) |
AU (1) | AU2005260377A1 (pt) |
BR (1) | BRPI0511454A (pt) |
WO (1) | WO2006004332A1 (pt) |
ZA (1) | ZA200608959B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9575061B2 (en) | 2009-10-20 | 2017-02-21 | Vanderbilt University | Liquid drop diagnostic assays |
CN102759621B (zh) * | 2011-04-26 | 2016-02-24 | 复旦大学 | 基于微流控芯片的高通量快速检测疟疾血清的方法 |
CN106290879A (zh) * | 2015-05-13 | 2017-01-04 | 上海凯创生物技术有限公司 | 恶性疟原虫胶体金法检测试剂盒 |
CN106290839A (zh) * | 2015-05-13 | 2017-01-04 | 上海凯创生物技术有限公司 | 恶性疟原虫乳胶法检测试剂盒 |
CN108761065A (zh) * | 2018-05-21 | 2018-11-06 | 苏州佑君环境科技有限公司 | 一种稀释碱性磷酸酶标识抗原用溶液及其制备方法 |
EP3971574A4 (en) * | 2019-07-15 | 2022-06-08 | Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Sciences | FUNCTIONALIZED BIOLOGICAL MULTILAYERY MEMBRANE IMMUNE SUPPORT, MANUFACTURING PROCESS AND APPLICATION |
CN110343161B (zh) * | 2019-07-30 | 2021-08-20 | 暨南大学 | 一种检测恶性疟原虫hrp2和间日疟原虫ldh的结合蛋白组合及其制备方法和应用 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3445816C1 (de) * | 1984-12-15 | 1986-06-12 | Behringwerke Ag, 3550 Marburg | Flaechenfoermiges diagnostisches Mittel |
US5130416A (en) * | 1986-08-13 | 1992-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA clone containing a genomic fragment of PfHRP-II gene from plasmodium falciparum |
US5001225A (en) * | 1986-12-08 | 1991-03-19 | Georgetown University | Monoclonal antibodies to a pan-malarial antigen |
FR2672290B1 (fr) * | 1991-02-05 | 1995-04-21 | Pasteur Institut | Sequences peptidiques specifiques des stades hepatiques de p. falciparum porteuses d'epitopes capables de stimuler les lymphocytes t. |
IT1217582B (it) * | 1988-05-13 | 1990-03-30 | Eniricerche Spa | Metodo immunoenzimatico in fase omogenea per la determinazione di anticorpi antisporozoita di plasmodium falciparum nel sangue umano |
IT1226712B (it) * | 1988-08-05 | 1991-02-05 | Eniricerche Spa | Metodo immunoenzimatico elisa monopiastra con inibizione competitiva per la rivelazione di anticorpi antisporozoitari di plasmodium falciparum. |
AU670108B2 (en) * | 1992-09-11 | 1996-07-04 | Becton Dickinson & Company | Improved antibodies to plasmodium falciparum |
US6022748A (en) * | 1997-08-29 | 2000-02-08 | Sandia Corporation - New Mexico Regents Of The University Of California | Sol-gel matrices for direct colorimetric detection of analytes |
FR2735478B1 (fr) * | 1995-06-13 | 1997-08-22 | Pasteur Institut | Molecules polypeptidiques de stade pre-erythrocytaire du paludisme |
AUPN803796A0 (en) * | 1996-02-13 | 1996-03-07 | Council Of The Queensland Institute Of Medical Research, The | Diagnostic assay for plasmodium falciparum |
WO1998035057A1 (en) * | 1997-02-06 | 1998-08-13 | The National University Of Singapore | Diagnosis of plasmodium infection by analysis of extrachromosomal genetic material |
US7025961B1 (en) * | 1999-03-04 | 2006-04-11 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-plasmodium composition and methods of use |
US20020102620A1 (en) * | 1999-05-07 | 2002-08-01 | S. Melissa Maret | Antibodies and peptides for detection of plasmodium vivax |
AR027370A1 (es) * | 2000-02-17 | 2003-03-26 | Lg Chemical Ltd | Inmunoensayo y reactivo de diagnostico para malaria, y correspondientes metodos de preparacion, vectores de expresion y transformantes |
WO2002058727A2 (en) * | 2001-01-26 | 2002-08-01 | Walter Reed Army Institute Of Research | Recombinant plasmodium falciparum merozoite protein-1/42 vaccine |
EP1423405A4 (en) * | 2001-03-26 | 2005-01-05 | Us Army | AMA-1 PROTEIN OF PLASMODIUM FALCIPARUM AND ITS APPLICATIONS |
EP1423091A4 (en) * | 2001-08-10 | 2005-07-20 | Univ California | SENSITIVE AND RAPID DETECTION OF PATHOGENIC ORGANISMS AND TOXINS USING FLUORESCENT POLYMER LIPIDS |
EP1497307B1 (en) * | 2002-04-01 | 2016-08-03 | Walter Reed Army Institute of Research | Recombinant p.falciparum merozoite protein-1 42 vaccine |
FR2839555B1 (fr) * | 2002-05-10 | 2007-07-27 | Bio Rad Pasteur | Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux |
JP4824312B2 (ja) * | 2002-11-26 | 2011-11-30 | ユニバーシティ オブ ユタ リサーチ ファンデーション | 微小孔物質、被分析物の局在化及び定量の方法、並びに被分析物の局在化及び定量用物品 |
AU2003296945A1 (en) * | 2002-12-12 | 2004-07-09 | Chiron Corporation | Device and method for in-line blood testing using biochips |
US20040248181A1 (en) * | 2003-06-03 | 2004-12-09 | Stenken Julie A. | Method and kit for enhancing extraction and quantification of target molecules using microdialysis |
US20060019406A1 (en) * | 2004-07-23 | 2006-01-26 | Ning Wei | Lateral flow device for the detection of large pathogens |
US20060127886A1 (en) * | 2004-12-15 | 2006-06-15 | Kaylor Rosann M | Sample-efficient lateral flow immunoassay |
-
2004
- 2004-06-30 KR KR1020040049985A patent/KR101035111B1/ko active IP Right Grant
-
2005
- 2005-06-28 AU AU2005260377A patent/AU2005260377A1/en not_active Abandoned
- 2005-06-28 WO PCT/KR2005/002010 patent/WO2006004332A1/en active Application Filing
- 2005-06-28 US US11/571,335 patent/US20090197347A1/en not_active Abandoned
- 2005-06-28 BR BRPI0511454-3A patent/BRPI0511454A/pt not_active IP Right Cessation
- 2005-06-28 CN CNA2005800214404A patent/CN101014858A/zh active Pending
-
2006
- 2006-10-30 ZA ZA200608959A patent/ZA200608959B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200608959B (en) | 2008-05-28 |
US20090197347A1 (en) | 2009-08-06 |
CN101014858A (zh) | 2007-08-08 |
AU2005260377A1 (en) | 2006-01-12 |
WO2006004332A1 (en) | 2006-01-12 |
KR101035111B1 (ko) | 2011-05-19 |
KR20060000985A (ko) | 2006-01-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Diao et al. | Accuracy of a nucleocapsid protein antigen rapid test in the diagnosis of SARS-CoV-2 infection | |
BRPI0511454A (pt) | imunoensaio para plasmodium falciparum e instrumentos de ensaio usados | |
ATE412179T1 (de) | Nachweis von arzneistoffen der methamphetamingruppe | |
BRPI0411059A (pt) | tiras de teste diagnóstico para detecção de um analito de interesse em uma amostra lìquida, para detecção de anticorpo de anti-hiv em uma amostra, e de teste de gravidez de imuno-diagnóstico, e, método de detecção de um anticorpo de interesse em uma amostra lìquida | |
BR112018016337A2 (pt) | anticorpos monoclonais da proteína ns1 de vírus antidengue | |
NO20076656L (no) | Forbedrede immunoassay metoder | |
Ezzat et al. | Anti-cyclic citrullinated peptide antibodies as a discriminating marker between rheumatoid arthritis and chronic hepatitis C-related polyarthropathy | |
JP4197180B2 (ja) | 検体中の内分泌物質測定方法 | |
WO2018152124A1 (en) | Rapid immunochromatographic lateral flow assay for early zika disease detection | |
BR112012029769A2 (pt) | processo para a detecção eletroquímica de reações de ligação | |
Song et al. | Chip-based cartilage oligomeric matrix protein detection in serum and synovial fluid for osteoarthritis diagnosis | |
Downs et al. | Correlation of serum and dried blood spot results for quantitation of Schistosoma circulating anodic antigen: a proof of principle | |
Hu et al. | Detection of hepatitis B virus PreS1 antigen using a time-resolved fluoroimmunoassay | |
Loufouma-Mbouaka et al. | Evaluation of rapid diagnostic tests and Enzyme Linked Immunoassay in the detection of malaria in ancient human remains | |
BR0200986A (pt) | Ensaio de combinação anticorpo - antìgeno da hepatite c para a detecção precoce da infecção | |
Gholizadeh et al. | Comparison of serum autoantibodies to desmogleins I, III in patients with oral lichen planus and healthy controls | |
Alcantara et al. | Heparin in plasma samples causes nonspecific binding to histones on Western blots | |
Shah et al. | Comparison of the analytic sensitivities of a recombinant immunoblot assay and the radioimmune precipitation assay for the detection of antibodies to Trypanosoma cruzi in patients with Chagas disease | |
BRPI1004526A2 (pt) | dispositivo semi-quantitativo de immunochromatographico e método para a determinação de hiv/aids via medida de solúvel cd40 ligand/cd154, um cd4+ equivalente de célula de t e a detecção simultánea de infecção de hiv via detecção de anticorpo de hiv | |
Rungrojcharoenkit et al. | Standardization of in-house anti-IgG and IgA ELISAs for the detection of COVID-19 | |
Sarkari et al. | A comparative study of antigen and antibody detection in visceral leishmaniasis using serum and urine-based ELISA | |
EP2444812A3 (en) | Improved immunoassay methods | |
Bai | Laboratory diagnosis of rickettsial infections | |
CN110741099B (zh) | 评估个体的登革热病毒感染严重程度的方法、检测装置及检测试剂盒 | |
TWI624668B (zh) | 評估個體之登革熱病毒感染嚴重程度的方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |