BRPI0511308B8 - moduladores seletivos receptores de androgênio e seus métodos de uso - Google Patents

moduladores seletivos receptores de androgênio e seus métodos de uso

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Publication number
BRPI0511308B8
BRPI0511308B8 BRPI0511308A BRPI0511308A BRPI0511308B8 BR PI0511308 B8 BRPI0511308 B8 BR PI0511308B8 BR PI0511308 A BRPI0511308 A BR PI0511308A BR PI0511308 A BRPI0511308 A BR PI0511308A BR PI0511308 B8 BRPI0511308 B8 BR PI0511308B8
Authority
BR
Brazil
Prior art keywords
bone
disorder
androgen receptor
selective androgen
promoting
Prior art date
Application number
BRPI0511308A
Other languages
English (en)
Inventor
D Miller Duane
T Dalton James
A Veverka Karen
Original Assignee
Univ Tennessee Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/861,923 external-priority patent/US8008348B2/en
Priority claimed from US10/863,524 external-priority patent/US20050038110A1/en
Priority claimed from US10/961,380 external-priority patent/US20060019931A1/en
Application filed by Univ Tennessee Res Found filed Critical Univ Tennessee Res Found
Publication of BRPI0511308A publication Critical patent/BRPI0511308A/pt
Publication of BRPI0511308B1 publication Critical patent/BRPI0511308B1/pt
Publication of BRPI0511308B8 publication Critical patent/BRPI0511308B8/pt

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    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
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Abstract

moduladores seletivos receptores de androgênio e seus métodos de uso. esta invenção provê compostos msra e seu uso no tratamento de uma variedade de doenças ou condições em um indivíduo, incluindo, entre elas, uma doença e/ou enfermi-dade de degeneração dos músculos ou uma doença e/ou enfermidade relacionada aos ossos.
BRPI0511308A 2004-06-07 2005-06-07 moduladores seletivos receptores de androgênio e seus métodos de uso BRPI0511308B8 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10/861,923 US8008348B2 (en) 2001-12-06 2004-06-07 Treating muscle wasting with selective androgen receptor modulators
US10/861,923 2004-06-07
US10/863,524 US20050038110A1 (en) 2000-08-24 2004-06-09 Selective androgen receptor modulators and methods of use thereof
US10/863,524 2004-06-09
US10/961,380 US20060019931A1 (en) 2003-10-14 2004-10-12 Treating bone-related disorders with selective androgen receptor modulators
US10/961,380 2004-10-12
PCT/US2005/019788 WO2005120483A2 (en) 2004-06-07 2005-06-07 Selective androgen receptor modulators and methods of use thereof

Publications (3)

Publication Number Publication Date
BRPI0511308A BRPI0511308A (pt) 2007-12-04
BRPI0511308B1 BRPI0511308B1 (pt) 2019-07-02
BRPI0511308B8 true BRPI0511308B8 (pt) 2021-05-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511308A BRPI0511308B8 (pt) 2004-06-07 2005-06-07 moduladores seletivos receptores de androgênio e seus métodos de uso

Country Status (14)

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EP (2) EP1753417B1 (pt)
JP (2) JP4201818B2 (pt)
AT (1) ATE552235T1 (pt)
AU (1) AU2005251781C1 (pt)
BR (1) BRPI0511308B8 (pt)
CA (1) CA2543827C (pt)
CY (1) CY1120469T1 (pt)
DK (1) DK2289872T3 (pt)
EA (2) EA011306B8 (pt)
GE (1) GEP20094851B (pt)
IL (1) IL178716A (pt)
MX (1) MXPA06013958A (pt)
PL (2) PL2289872T3 (pt)
WO (1) WO2005120483A2 (pt)

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US8853266B2 (en) 2001-12-06 2014-10-07 University Of Tennessee Research Foundation Selective androgen receptor modulators for treating diabetes
US8309603B2 (en) 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
PL2289872T3 (pl) * 2004-06-07 2017-12-29 University Of Tennessee Research Foundation Medyczne zastosowania selektywnego modulatora receptora androgenowego
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US7709516B2 (en) 2005-06-17 2010-05-04 Endorecherche, Inc. Helix 12 directed non-steroidal antiandrogens
EA200800710A1 (ru) * 2005-08-31 2008-06-30 Юниверсити Оф Теннесси Рисерч Фаундейшн Лечение почечной недостаточности, ожогов, ран и повреждений спинного мозга селективными модуляторами андрогенового рецептора
EP2040694A2 (en) * 2006-07-14 2009-04-01 VIB vzw Use of ppar-alpha agonists to treat skeletal muscle wasting disorders
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
JP5345534B2 (ja) 2006-08-24 2013-11-20 ユニバーシティ オブ テネシー リサーチ ファウンデーション 置換アシルアニリドおよびそれらの使用方法
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
US9284345B2 (en) 2007-04-12 2016-03-15 Endorecherche, Inc. 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators
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