BRPI0510175A - composições farmacêuticas comprimidas - Google Patents

composições farmacêuticas comprimidas

Info

Publication number
BRPI0510175A
BRPI0510175A BRPI0510175-1A BRPI0510175A BRPI0510175A BR PI0510175 A BRPI0510175 A BR PI0510175A BR PI0510175 A BRPI0510175 A BR PI0510175A BR PI0510175 A BRPI0510175 A BR PI0510175A
Authority
BR
Brazil
Prior art keywords
compressed pharmaceutical
polyethylene glycol
pharmaceutical compositions
pharmaceutical composition
agreeable
Prior art date
Application number
BRPI0510175-1A
Other languages
English (en)
Inventor
Norman Barras
Ian Cox
Original Assignee
Norgine Europe Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine Europe Bv filed Critical Norgine Europe Bv
Publication of BRPI0510175A publication Critical patent/BRPI0510175A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

COMPOSIçõES FARMACêUTICAS COMPRIMIDAS.A presente invenção fornece uma composição farmacêutica comprimida contendo polietileno glicol de peso molecular de 2000 a 4500, em que o polietileno glicol constitui de 80 a 99,5% em peso da composição, um ou mais eletrólitos para o tratamento da constipação, impacção fecal, retenção fecal, cólica e gás intestinal ou flatulência ou para lavagem ortostática, evacuação do cólon ou limpeza do cólon.Verificou-se, surpreendentemente, que uma composição farmacêutica comprimida contendo PEG, por exemplo, um comprimido sólido, é significativamente mais palatável do que as composições propostas anteriormente e é eficaz quando administrada. Verificou-se que a composição farmacêutica comprimida da invenção contendo polietileno glicol tem um sabor mais agradável e uma sensação mais agradável na boca do que as omposições líquidas, ou em pó seco ou granulares anteriormente propostas.
BRPI0510175-1A 2004-04-23 2005-04-25 composições farmacêuticas comprimidas BRPI0510175A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0409104.7A GB0409104D0 (en) 2004-04-23 2004-04-23 Compressed pharmaceutical compositions
PCT/GB2005/001555 WO2005102364A1 (en) 2004-04-23 2005-04-25 Compressed pharmaceutical compositions comprising peg and electrolytes

Publications (1)

Publication Number Publication Date
BRPI0510175A true BRPI0510175A (pt) 2007-10-02

Family

ID=32344298

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510175-1A BRPI0510175A (pt) 2004-04-23 2005-04-25 composições farmacêuticas comprimidas

Country Status (22)

Country Link
US (1) US20070298100A1 (pt)
EP (2) EP2263680B1 (pt)
JP (1) JP2007533719A (pt)
KR (1) KR20070001280A (pt)
CN (1) CN1950097A (pt)
AT (1) ATE496626T1 (pt)
AU (1) AU2005235345B8 (pt)
BR (1) BRPI0510175A (pt)
CA (1) CA2561649C (pt)
DE (1) DE602005026117D1 (pt)
DK (2) DK1742645T3 (pt)
ES (2) ES2519540T3 (pt)
GB (1) GB0409104D0 (pt)
IL (1) IL178722A0 (pt)
MX (1) MXPA06011906A (pt)
NO (1) NO20064780L (pt)
PL (2) PL2263680T3 (pt)
PT (2) PT1742645E (pt)
RU (1) RU2006137347A (pt)
SI (2) SI1742645T1 (pt)
WO (1) WO2005102364A1 (pt)
ZA (1) ZA200608496B (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1877039A4 (en) * 2005-05-06 2010-08-18 Salix Pharmaceuticals Inc Polyethylene glycol GUT CLEANING COMPOSITION
ES2278537B1 (es) * 2006-01-30 2008-09-16 Laboratorios Casen-Fleet, S.L. Procedimiento de fabricacion de una solucion a base de polietilenglicol con electrolitos, producto obtenido y uso.
US20090130048A1 (en) * 2007-11-19 2009-05-21 Oronsky Bryan Todd Topical Composition for Treating Pain
US8784872B2 (en) * 2007-11-19 2014-07-22 Comgenrx, Inc. Formulation for decreasing tobacco, alcohol, drug or food consumption
EP2304146B1 (de) 2008-06-06 2014-01-22 Roto Frank Ag Ausstellvorrichtung für ein fenster, eine tür oder dergleichen
US20100104614A1 (en) * 2008-06-27 2010-04-29 Oronsky Bryan T Providone compositions for wound healing
PL2421373T3 (pl) 2009-04-21 2020-03-31 Dale R. Bachwich Układ do płukania okrężnicy
CN102448976A (zh) * 2009-06-03 2012-05-09 加拿大阿普塔利斯制药公司 L-糖结肠清洁剂及其应用
GB0913295D0 (en) * 2009-07-30 2009-09-02 Norgine Bv Improvements in and relating to pharmaceutical compositions
EP2509695A1 (en) * 2009-12-07 2012-10-17 Aptalis Pharma Canada, Inc. Methods for purifying monosaccharide mixtures containing ionic impurities
CN101766648B (zh) * 2010-03-02 2012-01-11 舒泰神（北京）生物制药股份有限公司 聚乙二醇电解质颗粒制剂及其制造方法
DE202010012256U1 (de) * 2010-09-07 2010-11-11 Krewel Meuselbach Gmbh Abführmittel
DK201100161U3 (da) * 2010-11-04 2012-02-24 Norgine Bv Formuleringer med polyethylenglycol og mannitol
AU2011100528B4 (en) * 2011-05-10 2011-08-25 Norgine Bv Formulations
DE202010016235U1 (de) 2010-12-06 2011-05-19 Norgine B.V. Formulierungen
BE1019493A3 (fr) * 2010-11-04 2012-07-03 Norgine Bv Formulations.
CA2825808C (en) 2011-01-28 2020-09-01 William A. Shaver Method, composition and package for bowel cleansing
PT2862566T (pt) * 2011-01-31 2022-06-02 Norgine Healthcare B V Melhorias em, e relativas a, composições
TWI535461B (zh) 2011-03-11 2016-06-01 諾金私人有限公司 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法
CN102133225B (zh) * 2011-03-18 2012-11-21 海南锦瑞制药股份有限公司 一种复方聚乙二醇电解质散剂及其制备方法
US20150056140A1 (en) * 2011-10-27 2015-02-26 Thomas Julius Borody Electrolyte purgatives
CN102600201B (zh) * 2012-02-07 2014-07-16 舒泰神（北京）生物制药股份有限公司 用于通便和清肠的药物组合物及其制备方法
IN2015DN01704A (pt) 2012-09-11 2015-05-22 Norgine Bv
EA034234B1 (ru) * 2013-03-15 2020-01-20 Брейнтри Лабораторис, Инк. Пероральные фармацевтические таблетированные композиции двойного применения, содержащие сульфат натрия или его комбинацию с другими сульфатными солями, и способы их получения и применения
IL252881B (en) * 2014-12-12 2022-06-01 Ojai Energetics Pbc Microencapsulated cannabinoid preparations
US10350165B2 (en) 2014-12-12 2019-07-16 Ojai Energetics Pbc Methods and systems for forming stable droplets
FR3056109B1 (fr) * 2016-09-21 2019-10-11 Pierre Fabre Medicament Utilisation de formulations solides de polyethylene glycol dans le traitement de la constipation
CN107028876B (zh) * 2016-10-09 2020-09-29 舒泰神（北京）生物制药股份有限公司 聚乙二醇电解质口服液及其制备方法
US11339264B2 (en) 2017-07-20 2022-05-24 Solvay Sa Functionalized particulate bicarbonate as blowing agent, foamable polymer composition containing it, and its use in manufacturing a thermoplastic foamed polymer
WO2019151829A1 (ko) * 2018-02-01 2019-08-08 주식회사태준제약 장세척 조성물
KR20190093490A (ko) 2018-02-01 2019-08-09 주식회사태준제약 장세척 조성물
CN110433174A (zh) * 2019-07-17 2019-11-12 华南理工大学 一种高依从性的复方聚乙二醇电解质散剂及其制备方法与应用
CN111617102B (zh) * 2020-05-25 2022-05-31 南京金凯木纳米材料有限公司 一种含聚乙二醇的电解质散剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121663A (en) * 1956-02-09 1964-02-18 Plough Lab Inc Carbon dioxide releasing laxative suppository
US5229132A (en) * 1985-02-22 1993-07-20 Grimberg Georges Serge Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time
EP0231356A1 (en) * 1985-08-01 1987-08-12 Braintree Laboratories, Inc. Low-sodium laxative and lavage formulation
US5273758A (en) * 1991-03-18 1993-12-28 Sandoz Ltd. Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms
US6121663A (en) * 1997-05-22 2000-09-19 Advanced Micro Devices, Inc. Local interconnects for improved alignment tolerance and size reduction
FR2784897B1 (fr) * 1998-10-27 2002-11-29 Agronomique Inst Nat Rech Utilisation d'un laxatif osmotique non fermente dans le traitement et la prevention des cancers colorectaux
US6444198B1 (en) * 1999-02-22 2002-09-03 Smithkline Beecham Corporation Effervescent laxatives
DE19933148A1 (de) * 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
JP2007511610A (ja) * 2003-11-17 2007-05-10 ブレーントリー ラボラトリーズ インコーポレーティッド 治療用ｐｅｇ溶液濃縮物
US7687075B2 (en) * 2003-11-19 2010-03-30 Salix Pharmaceuticals, Ltd. Colonic purgative composition with soluble binding agent

Also Published As

Publication number Publication date
PT1742645E (pt) 2011-04-29
DK2263680T3 (en) 2014-12-08
EP2263680B1 (en) 2014-08-27
ES2519540T3 (es) 2014-11-07
CA2561649C (en) 2014-10-14
IL178722A0 (en) 2007-02-11
RU2006137347A (ru) 2008-05-27
NO20064780L (no) 2007-01-18
PL2263680T3 (pl) 2015-02-27
DK1742645T3 (da) 2011-05-09
ES2361816T3 (es) 2011-06-22
AU2005235345A1 (en) 2005-11-03
CA2561649A1 (en) 2005-11-03
US20070298100A1 (en) 2007-12-27
CN1950097A (zh) 2007-04-18
PL1742645T3 (pl) 2011-06-30
AU2005235345B8 (en) 2011-05-12
MXPA06011906A (es) 2007-01-25
EP1742645B1 (en) 2011-01-26
AU2005235345B2 (en) 2011-04-14
EP2263680A1 (en) 2010-12-22
WO2005102364A1 (en) 2005-11-03
SI1742645T1 (sl) 2011-05-31
DE602005026117D1 (de) 2011-03-10
EP1742645A1 (en) 2007-01-17
SI2263680T1 (sl) 2015-01-30
GB0409104D0 (en) 2004-05-26
PT2263680E (pt) 2014-11-19
ZA200608496B (en) 2008-07-30
JP2007533719A (ja) 2007-11-22
ATE496626T1 (de) 2011-02-15
KR20070001280A (ko) 2007-01-03

Similar Documents

Publication Publication Date Title
BRPI0510175A (pt) composições farmacêuticas comprimidas
IL169469A (en) Folic acid derivatives containing disulfide bonds, their pharmaceutical compositions and their use
IL188494A0 (en) Novel 2,4-dianlinopyrimidine derivatives, the preparation thereof, their use as medicaments, pharmaceutical compositions and, in particular, as ikk inhibitors
IL176005A0 (en) 2,6-bisheteroaryl-4-aminopyrimidine derivatives and pharmaceutical compositions containing the same
WO2008036932A3 (en) Compositions and methods comprising boswellia species
MXPA05013232A (es) Composicion en forma de pulverizador que comprende un activo farmaceutico, al menos una silicona volatil y una fase aceitosa no volatil.
MXPA05012507A (es) Composiciones farmaceuticas de vareniclina.
IL174479A (en) The derivatives of myastrin, pharmaceutical preparations containing them and their uses
WO2006052876A3 (en) Insecticidal compositions suitable for use in preparation of insecticidal granular fertilizer and insecticidal formulations
TW200630343A (en) 2-Alkoxy-3,4,5-trihydroxy-alkylamides, preparation thereof, compositions containing them and use thereof
ATE504286T1 (de) Antitranspirant- oder deodorantzusammensetzungen
WO2004064542A8 (fr) Composition pour une administration par voie orale contenant des capsaicinoïdes
IL181216A0 (en) 3, 5-seco-4-norcholestane derivatives and pharmaceutical compositions containing the same
ITRM20030363A0 (it) Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico diesse.
WO2005092362A3 (de) Pharmazeutisches kombinationspräparat enthaltend ein therapeutisches protein
WO2006110185A3 (en) Antiinfective lipopeptides
ATE442057T1 (de) Interessante nährstoff- und organoleptische eigenschaften zeigende lipidische zusammensetzung
DK1110550T4 (da) Præparat omfattende ascorbinsyre som hovedbestanddel og pektin
WO2006004903A3 (en) 1,2-bis-(substituted-phenyl)-2-propen-1-ones and pharmaceutical compositions thereof
ATE417619T1 (de) Sporopollenin enthaltende lösliche zusammensetzung und verwendung
WO2005072736A3 (en) Stable gabapentin compositions
HRP20090547T1 (en) Pharmaceutical compositions comprising zd6474
IL191560A0 (en) 3,4-dihydrobenzoxazine derivatives and pharmaceutical compositions containing the same
MX2008006476A (es) Composiciones de lipopeptidos.
ATE384515T1 (de) Triazinderivat, amid-basiertes öl und ein eutektisches gemisch aus n-butyl- phthalimid/isopropylphthalimid enthaltende kosmetische zusammensetzungen

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: NORGINE BV (NL)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.