BRPI0509497A - seqüência de polipeptìdeos na modulação do efeito imunosupressor de proteìnas virais - Google Patents
seqüência de polipeptìdeos na modulação do efeito imunosupressor de proteìnas viraisInfo
- Publication number
- BRPI0509497A BRPI0509497A BRPI0509497-6A BRPI0509497A BRPI0509497A BR PI0509497 A BRPI0509497 A BR PI0509497A BR PI0509497 A BRPI0509497 A BR PI0509497A BR PI0509497 A BRPI0509497 A BR PI0509497A
- Authority
- BR
- Brazil
- Prior art keywords
- modulating
- polypeptide sequence
- viral proteins
- immunosuppressive effect
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SEQUêNCIA DE POLIPEPTìDEOS ENVOLVIDA NA MODULAçãO DO EFEITO IMUNOSUPRESSOR DE PROTEìNAS VIRAIS A presente invenção se refere a um polipeptídeo tendo uma seqüência de 7 a 20 resíduos de aminoácido, que é capaz de modular as propriedades imunosupressoras de uma proteína viral, ou um fragmento desta, contra o hospedeiro no qual ela é expressa (seqüência de imunosupressão-modulatória) quando substitui a seqüência homóloga de referida proteína viral ou fragmento, referido polipeptídeo compreendendo a seqüência de amino ácido de consenso seguinte mínimo: X1 Y9 Y10 Y11 CY12 X2(subscritos) no qual X1 e X2 são selecionados para impactarem nas referidas propriedades imunosupressora, e Y9 a Y12 representam resíduos de aminoácido variáveis.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04290838 | 2004-03-30 | ||
EP04290838.4 | 2004-03-30 | ||
PCT/EP2005/003339 WO2005095442A1 (en) | 2004-03-30 | 2005-03-30 | Polypeptide sequence involved in the modulation of the immunosuppresive effect of viral proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0509497A true BRPI0509497A (pt) | 2007-09-11 |
BRPI0509497B1 BRPI0509497B1 (pt) | 2022-07-19 |
Family
ID=34896141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509497-6A BRPI0509497B1 (pt) | 2004-03-30 | 2005-03-30 | Seqüência de polipeptídeos envolvida na modulação do efeito imunosupressor de proteínas virais |
Country Status (14)
Country | Link |
---|---|
US (2) | US8178657B2 (pt) |
EP (1) | EP1732585B1 (pt) |
JP (1) | JP5060284B2 (pt) |
CN (1) | CN1961001B (pt) |
AT (1) | ATE472334T1 (pt) |
AU (1) | AU2005229411B2 (pt) |
BR (1) | BRPI0509497B1 (pt) |
CA (1) | CA2561376C (pt) |
DE (1) | DE602005022056D1 (pt) |
ES (1) | ES2347445T3 (pt) |
IL (1) | IL178205A (pt) |
MX (1) | MXPA06011272A (pt) |
WO (1) | WO2005095442A1 (pt) |
ZA (1) | ZA200608178B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9777044B2 (en) | 2003-05-02 | 2017-10-03 | Centre National De La Recherche Scientifique (Cnrs) | GLUT-1 as a receptor for HTLV envelopes and its uses |
WO2006103562A2 (en) | 2005-03-30 | 2006-10-05 | Centre National De La Recherche Scientifique (Cnrs) | Endogenous retrovirus and proteins encoded by env gene as a target for cancer treatment |
US20070185025A1 (en) * | 2005-09-11 | 2007-08-09 | The Trustees Of Columbia University In The City Of New York | Filoviral immunosuppressive peptides and uses thereof |
US20080299150A1 (en) * | 2007-05-08 | 2008-12-04 | Sankhia Corporation | Method and system for processing immuno-competent cells in view of an antiviral therapy, and related therapeutic process |
US8323891B2 (en) * | 2008-08-01 | 2012-12-04 | Claflin University | miRNA triplex formations for the downregulation of viral replication |
RU2008140688A (ru) * | 2008-10-15 | 2010-04-20 | Михаил Аркадьевич Шурдов (RU) | Иммуносупрессивный пептид |
DK2376917T3 (en) | 2009-01-09 | 2016-07-18 | Centre Nat Rech Scient | New receptorbindingsligander, use thereof for the detection of cells of biological interest |
WO2011092199A1 (en) * | 2010-01-26 | 2011-08-04 | Institut Gustave Roussy | Mutated xmrv env proteins in the immunosuppressive domain |
US20130197612A1 (en) | 2010-02-26 | 2013-08-01 | Jack W. Lasersohn | Electromagnetic Radiation Therapy |
WO2012035369A1 (en) | 2010-09-17 | 2012-03-22 | Centre National De La Recherche Scientifique | Method for the diagnosis and/or prognosis of inflammatory states |
RU2591817C2 (ru) * | 2011-07-20 | 2016-07-20 | Мериал Лимитед | Рекомбинантная вакцина вируса лейкемии кошек, содержащая оптимизированный ген оболочки вируса лейкемии кошек |
US9636396B2 (en) | 2011-12-07 | 2017-05-02 | Centre National De La Recherche Scientifique | Mutant human and simian immunodeficiency virus ENV proteins with reduced immunosuppressive properties |
CN104169295B (zh) | 2011-12-07 | 2020-07-28 | 维洛克塞斯简易股份公司 | 突变的慢病毒env蛋白及其用作药物的用途 |
EP3004143B1 (en) | 2013-06-07 | 2019-10-23 | Viroxis S.A.S. | Mutated non-primate lentiviral env proteins and their use as drugs |
US11535654B2 (en) * | 2015-06-11 | 2022-12-27 | Keio University | Fusion protein or conjugated protein, intracellular delivery carrier, partial peptide, cell membrane permeation enhancer, DNA, and vector |
CA2999792A1 (en) * | 2015-10-01 | 2017-04-06 | Magdalena Janina LASKA | Use of human derived immunosuppressive proteins and peptides as medicaments |
JP7277466B2 (ja) | 2017-09-01 | 2023-05-19 | インプラザー エー・ペー・エス | 疾患の予防および/または治療における使用のためのワクチン |
AU2019343045A1 (en) | 2018-09-18 | 2021-05-13 | Vnv Newco Inc. | ARC-based capsids and uses thereof |
US11129892B1 (en) | 2020-05-18 | 2021-09-28 | Vnv Newco Inc. | Vaccine compositions comprising endogenous Gag polypeptides |
AU2022208199A1 (en) | 2021-01-13 | 2023-07-13 | Centre National De La Recherche Scientifique | Measles-hiv or measles-htlv vaccine |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4822606A (en) | 1986-04-07 | 1989-04-18 | Duke University | Immunosuppressive synthetic peptides and analogs thereof based on retroviral envelope sequences |
EP0699758B1 (en) * | 1988-12-13 | 2002-07-24 | President And Fellows Of Harvard College | Prototype felv isolates for use in disease models and vaccines |
FR2771011B1 (fr) * | 1997-11-17 | 2000-01-28 | Hippocampe | Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale |
FR2780069B1 (fr) * | 1998-06-23 | 2002-06-28 | Inst Nat Sante Rech Med | Famille de sequences nucleiques et de sequences proteiques deduites presentant des motifs retroviraux endogenes humains et leurs applications |
JP2003512844A (ja) * | 1999-10-28 | 2003-04-08 | ユニヴェルシテ・ドゥ・ジュネーブ | 多発性硬化症関連スーパー抗原 |
CA2429755A1 (en) | 2000-12-11 | 2002-06-20 | Tufts University | Treatment and prevention of ebv infection and ebv-associated disorders |
GB0112126D0 (en) | 2001-05-18 | 2001-07-11 | Allergene Inc | Composition |
-
2005
- 2005-03-30 ZA ZA200608178A patent/ZA200608178B/xx unknown
- 2005-03-30 EP EP05716455A patent/EP1732585B1/en active Active
- 2005-03-30 JP JP2007505491A patent/JP5060284B2/ja active Active
- 2005-03-30 CN CN2005800161375A patent/CN1961001B/zh active Active
- 2005-03-30 DE DE602005022056T patent/DE602005022056D1/de active Active
- 2005-03-30 CA CA2561376A patent/CA2561376C/en active Active
- 2005-03-30 BR BRPI0509497-6A patent/BRPI0509497B1/pt active IP Right Grant
- 2005-03-30 AT AT05716455T patent/ATE472334T1/de not_active IP Right Cessation
- 2005-03-30 ES ES05716455T patent/ES2347445T3/es active Active
- 2005-03-30 AU AU2005229411A patent/AU2005229411B2/en active Active
- 2005-03-30 MX MXPA06011272A patent/MXPA06011272A/es not_active Application Discontinuation
- 2005-03-30 WO PCT/EP2005/003339 patent/WO2005095442A1/en active Application Filing
- 2005-03-30 US US11/547,399 patent/US8178657B2/en active Active
-
2006
- 2006-09-20 IL IL178205A patent/IL178205A/en active IP Right Grant
-
2012
- 2012-02-17 US US13/399,208 patent/US8597657B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP2008506357A (ja) | 2008-03-06 |
DE602005022056D1 (de) | 2010-08-12 |
WO2005095442A8 (en) | 2006-11-02 |
ZA200608178B (en) | 2008-10-29 |
CA2561376A1 (en) | 2005-10-13 |
US20080008683A1 (en) | 2008-01-10 |
AU2005229411B2 (en) | 2010-11-18 |
ATE472334T1 (de) | 2010-07-15 |
MXPA06011272A (es) | 2007-04-17 |
WO2005095442A1 (en) | 2005-10-13 |
IL178205A (en) | 2015-05-31 |
EP1732585B1 (en) | 2010-06-30 |
US8597657B2 (en) | 2013-12-03 |
JP5060284B2 (ja) | 2012-10-31 |
US8178657B2 (en) | 2012-05-15 |
CA2561376C (en) | 2016-06-21 |
IL178205A0 (en) | 2006-12-31 |
BRPI0509497B1 (pt) | 2022-07-19 |
AU2005229411A1 (en) | 2005-10-13 |
EP1732585A1 (en) | 2006-12-20 |
CN1961001B (zh) | 2012-09-05 |
CN1961001A (zh) | 2007-05-09 |
ES2347445T3 (es) | 2010-10-29 |
US20120189647A1 (en) | 2012-07-26 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: INSTITUT GUSTAVE ROUSSY (FR) ; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) ; UNIVERSITE PARIS-SACLAY (FR) |
|
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/03/2005, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |