BRPI0418979A - 2,3-aminomutases de alanina - Google Patents
2,3-aminomutases de alaninaInfo
- Publication number
- BRPI0418979A BRPI0418979A BRPI0418979-5A BRPI0418979A BRPI0418979A BR PI0418979 A BRPI0418979 A BR PI0418979A BR PI0418979 A BRPI0418979 A BR PI0418979A BR PI0418979 A BRPI0418979 A BR PI0418979A
- Authority
- BR
- Brazil
- Prior art keywords
- alanine
- aminomutases
- cells
- disclosed
- methods
- Prior art date
Links
- 108010007014 alanine 2,3-aminomutase Proteins 0.000 title abstract 3
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 abstract 2
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 abstract 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 abstract 1
- 229940000635 beta-alanine Drugs 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 229940014662 pantothenate Drugs 0.000 abstract 1
- 235000019161 pantothenic acid Nutrition 0.000 abstract 1
- 239000011713 pantothenic acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
2,3-AMINOMUTASES DE ALANINA. A presente invenção refere-se a seqüências de 2,3-aminomutase de alanina são divulgadas, assim como células tendo atividade de 2,3-aminomutase de alanina e métodos de seleção de tais células. Métodos para a produção de beta-alanina, pantotenato, ácido 3-hidroxipropiónico, bem como outros compostos orgânicas são divulgados.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2004/024686 WO2006022664A2 (en) | 2004-07-30 | 2004-07-30 | Alanine 2, 3 aminomutases |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0418979A true BRPI0418979A (pt) | 2007-12-11 |
Family
ID=35967948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0418979-5A BRPI0418979A (pt) | 2004-07-30 | 2004-07-30 | 2,3-aminomutases de alanina |
Country Status (9)
Country | Link |
---|---|
US (1) | US20090031453A1 (pt) |
EP (3) | EP2292750A3 (pt) |
JP (1) | JP2008507970A (pt) |
CN (1) | CN1993377A (pt) |
AU (1) | AU2004322803A1 (pt) |
BR (1) | BRPI0418979A (pt) |
CA (1) | CA2574280A1 (pt) |
MX (1) | MX2007001195A (pt) |
WO (1) | WO2006022664A2 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2473716A1 (en) | 2002-01-18 | 2003-07-31 | Cargill, Incorporated | Alanine 2,3- aminomutase |
ATE543873T1 (de) | 2003-12-04 | 2012-02-15 | Novozymes As | Herstellung von 3-hydroxypropionsäure mittels beta-alanine-pyruvat-aminotrransferase |
CN101068923A (zh) * | 2004-10-25 | 2007-11-07 | 科德克希思公司 | 改良的丙氨酸2,3-氨基变位酶和相关多核苷酸 |
US8030051B2 (en) * | 2005-10-14 | 2011-10-04 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
BRPI0806695A2 (pt) * | 2007-01-12 | 2014-06-03 | Univ Colorado | Composições e métodos para aumentar a tolerância à produção de produtos químicos produzidos por microorganismos |
US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
EP2076044A1 (en) | 2007-12-14 | 2009-07-01 | Thomson Licensing | Compressed video data stream switching method |
DE102008020688B3 (de) | 2008-04-24 | 2009-11-05 | Evonik Stockhausen Gmbh | Verfahren zur Herstellung und Aufreinigung wässriger Phasen |
US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
WO2011038364A1 (en) | 2009-09-27 | 2011-03-31 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
WO2011063363A2 (en) * | 2009-11-20 | 2011-05-26 | Opx Biotechnologies, Inc. | Production of an organic acid and/or related chemicals |
US8911978B2 (en) | 2010-07-02 | 2014-12-16 | Metabolic Explorer | Method for the preparation of hydroxy acids |
BR112013012630B1 (pt) | 2010-11-22 | 2021-09-08 | Novozymes, Inc. | Célula de levedura geneticamente modificada, e, método para produzir 3-hp |
TWI542695B (zh) * | 2010-12-15 | 2016-07-21 | 日星股份有限公司 | 牙周病原菌血漿或血清抗體價檢查套組 |
WO2012081723A1 (ja) | 2010-12-17 | 2012-06-21 | 三菱化学株式会社 | 合成経路作成装置、合成経路作成方法及び合成経路作成プログラムならびに3-ヒドロキシプロピオン酸、クロトニルアルコールおよびブタジエンの製造方法 |
US8765426B2 (en) | 2011-04-07 | 2014-07-01 | E I Du Pont De Nemours And Company | Pantothenic acid biosynthesis in zymomonas |
JP2014528726A (ja) | 2011-09-30 | 2014-10-30 | ノボザイムス,インコーポレイティド | デヒドロゲナーゼ変異体およびこれをコードするポリヌクレオチド |
IN2015DN01858A (pt) | 2012-08-10 | 2015-05-29 | Opx Biotechnologies Inc | |
CA2891130A1 (en) | 2012-11-30 | 2014-06-05 | Novozymes, Inc. | 3-hydroxypropionic acid production by recombinant yeasts |
US20150057465A1 (en) | 2013-03-15 | 2015-02-26 | Opx Biotechnologies, Inc. | Control of growth-induction-production phases |
US9512057B2 (en) | 2013-03-15 | 2016-12-06 | Cargill, Incorporated | 3-hydroxypropionic acid compositions |
JP6603658B2 (ja) | 2013-07-19 | 2019-11-06 | カーギル インコーポレイテッド | 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法 |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
CN104593398B (zh) * | 2013-11-01 | 2017-06-06 | 中国科学院微生物研究所 | 一种高L‑天冬氨酸α羧化酶活性的工程菌及其在生产β‑丙氨酸中的应用 |
EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
CN117247883A (zh) * | 2021-12-06 | 2023-12-19 | 中国科学院天津工业生物技术研究所 | 来自Taxus chinensis的L-苯丙氨酸变位酶在合成β-丙氨酸中的应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
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US564823A (en) | 1896-07-28 | Pencil-sharpener | ||
US5264550A (en) | 1985-04-15 | 1993-11-23 | Scios Nova Inc. | Human anti-inflammatory phospholipase inhibitor protein |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
US7018809B1 (en) | 1991-09-19 | 2006-03-28 | Genentech, Inc. | Expression of functional antibody fragments |
FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
US5691188A (en) | 1994-02-14 | 1997-11-25 | American Cyanamid Company | Transformed yeast cells expressing heterologous G-protein coupled receptor |
ES2336858T3 (es) * | 1996-11-13 | 2010-04-16 | E.I. Du Pont De Nemours And Company | Metodo para la produccion de 1,3-propanodiol mediante organismos recombinantes. |
US6248874B1 (en) * | 1998-11-24 | 2001-06-19 | Wisconsin Alumni Research Foundation | DNA molecules encoding bacterial lysine 2,3-aminomutase |
US7452701B2 (en) * | 1998-11-24 | 2008-11-18 | Wisconsin Alumni Research Foundation | Methods for the preparation of β-amino acids |
DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
DE19855312A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
EP1642596A3 (en) | 1999-05-07 | 2006-04-12 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to B cell surface markers |
DE60030403D1 (de) | 1999-08-30 | 2006-10-12 | Wisconsin Alumni Res Found | Herstellung von 3-hydroxypropionsäure in rekombinanten organismen |
CA2473716A1 (en) * | 2002-01-18 | 2003-07-31 | Cargill, Incorporated | Alanine 2,3- aminomutase |
ATE543873T1 (de) * | 2003-12-04 | 2012-02-15 | Novozymes As | Herstellung von 3-hydroxypropionsäure mittels beta-alanine-pyruvat-aminotrransferase |
CN101068923A (zh) * | 2004-10-25 | 2007-11-07 | 科德克希思公司 | 改良的丙氨酸2,3-氨基变位酶和相关多核苷酸 |
WO2007047680A2 (en) * | 2005-10-14 | 2007-04-26 | Cargill, Incorporated | Increasing the activity of radical s-adenosyl methionine (sam) enzymes |
-
2004
- 2004-07-30 JP JP2007523520A patent/JP2008507970A/ja active Pending
- 2004-07-30 EP EP10191975A patent/EP2292750A3/en not_active Withdrawn
- 2004-07-30 AU AU2004322803A patent/AU2004322803A1/en not_active Abandoned
- 2004-07-30 CN CNA2004800437200A patent/CN1993377A/zh active Pending
- 2004-07-30 WO PCT/US2004/024686 patent/WO2006022664A2/en active Application Filing
- 2004-07-30 EP EP04786144A patent/EP1786831A4/en not_active Withdrawn
- 2004-07-30 BR BRPI0418979-5A patent/BRPI0418979A/pt not_active Application Discontinuation
- 2004-07-30 US US11/658,795 patent/US20090031453A1/en not_active Abandoned
- 2004-07-30 MX MX2007001195A patent/MX2007001195A/es not_active Application Discontinuation
- 2004-07-30 CA CA002574280A patent/CA2574280A1/en not_active Abandoned
- 2004-07-30 EP EP10191970A patent/EP2292749A3/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2004322803A1 (en) | 2006-03-02 |
CN1993377A (zh) | 2007-07-04 |
MX2007001195A (es) | 2007-10-03 |
US20090031453A1 (en) | 2009-01-29 |
EP1786831A2 (en) | 2007-05-23 |
EP2292749A3 (en) | 2011-12-21 |
EP2292749A2 (en) | 2011-03-09 |
EP2292750A3 (en) | 2011-12-21 |
EP2292750A2 (en) | 2011-03-09 |
WO2006022664A3 (en) | 2006-06-15 |
WO2006022664A2 (en) | 2006-03-02 |
JP2008507970A (ja) | 2008-03-21 |
CA2574280A1 (en) | 2006-03-02 |
EP1786831A4 (en) | 2008-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |