BRPI0408467A - cromenonaindóis - Google Patents
cromenonaindóisInfo
- Publication number
- BRPI0408467A BRPI0408467A BRPI0408467-5A BRPI0408467A BRPI0408467A BR PI0408467 A BRPI0408467 A BR PI0408467A BR PI0408467 A BRPI0408467 A BR PI0408467A BR PI0408467 A BRPI0408467 A BR PI0408467A
- Authority
- BR
- Brazil
- Prior art keywords
- actions
- resorption
- inhibition
- derivatives
- cromenonaindoles
- Prior art date
Links
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 230000001270 agonistic effect Effects 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003478 serotonin 5-HT2 receptor agonist Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10315285A DE10315285A1 (de) | 2003-04-04 | 2003-04-04 | Chromenonindole |
| PCT/EP2004/002351 WO2004087692A1 (de) | 2003-04-04 | 2004-03-08 | Chromenonindole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0408467A true BRPI0408467A (pt) | 2006-04-04 |
Family
ID=32981019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0408467-5A BRPI0408467A (pt) | 2003-04-04 | 2004-03-08 | cromenonaindóis |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7968551B2 (enExample) |
| EP (1) | EP1611126B1 (enExample) |
| JP (1) | JP4740114B2 (enExample) |
| KR (1) | KR20050119673A (enExample) |
| CN (1) | CN1768056A (enExample) |
| AR (1) | AR043834A1 (enExample) |
| AT (1) | ATE446959T1 (enExample) |
| AU (1) | AU2004226279B2 (enExample) |
| BR (1) | BRPI0408467A (enExample) |
| CA (1) | CA2520892C (enExample) |
| DE (2) | DE10315285A1 (enExample) |
| DK (1) | DK1611126T3 (enExample) |
| ES (1) | ES2335665T3 (enExample) |
| MX (1) | MXPA05010483A (enExample) |
| PL (2) | PL377730A1 (enExample) |
| PT (1) | PT1611126E (enExample) |
| WO (1) | WO2004087692A1 (enExample) |
| ZA (1) | ZA200508922B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1792629A4 (en) | 2004-08-25 | 2010-08-25 | Takeda Pharmaceutical | MEANS FOR THE PREVENTION / TREATMENT OF STRESS-RELATED HARNINE INCONTINENCE AND PRECAUTIONARY METHOD FOR THIS |
| EP2727585A1 (en) | 2006-05-16 | 2014-05-07 | Takeda Pharmaceutical Company Limited | In-vivo screening method |
| US20100266504A1 (en) | 2007-11-15 | 2010-10-21 | Takahiro Matsumoto | Condensed pyridine derivative and use thereof |
| US20120253036A1 (en) | 2009-12-11 | 2012-10-04 | Yukinori Nagakura | Agent for treating fibromyalgia |
| CN103304547A (zh) * | 2012-03-13 | 2013-09-18 | 中国药科大学 | 一种抗抑郁药维拉唑酮的制备方法 |
| CN104045608B (zh) * | 2013-03-11 | 2016-06-01 | 天津药物研究院有限公司 | 一种取代哌嗪化合物及制备维拉佐酮中间体的方法 |
| CN104059046B (zh) * | 2013-03-18 | 2017-02-08 | 江苏恩华药业股份有限公司 | 黄酮类衍生物及其应用 |
| WO2015014256A1 (en) | 2013-07-29 | 2015-02-05 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
| US10316025B2 (en) | 2015-06-03 | 2019-06-11 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use and use thereof |
| US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
| WO2020087031A1 (en) | 2018-10-26 | 2020-04-30 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4333254A1 (de) | 1993-09-30 | 1995-04-06 | Merck Patent Gmbh | Piperidine und Piperazine |
| DE19730989A1 (de) | 1997-07-18 | 1999-01-21 | Merck Patent Gmbh | Piperazin-Derivate |
-
2003
- 2003-04-04 DE DE10315285A patent/DE10315285A1/de not_active Withdrawn
-
2004
- 2004-03-08 DE DE502004010296T patent/DE502004010296D1/de not_active Expired - Lifetime
- 2004-03-08 WO PCT/EP2004/002351 patent/WO2004087692A1/de not_active Ceased
- 2004-03-08 AU AU2004226279A patent/AU2004226279B2/en not_active Ceased
- 2004-03-08 KR KR1020057018642A patent/KR20050119673A/ko not_active Withdrawn
- 2004-03-08 ES ES04718300T patent/ES2335665T3/es not_active Expired - Lifetime
- 2004-03-08 US US10/551,997 patent/US7968551B2/en not_active Expired - Fee Related
- 2004-03-08 CA CA2520892A patent/CA2520892C/en not_active Expired - Fee Related
- 2004-03-08 AT AT04718300T patent/ATE446959T1/de active
- 2004-03-08 MX MXPA05010483A patent/MXPA05010483A/es not_active Application Discontinuation
- 2004-03-08 PL PL377730A patent/PL377730A1/pl unknown
- 2004-03-08 JP JP2006504582A patent/JP4740114B2/ja not_active Expired - Fee Related
- 2004-03-08 BR BRPI0408467-5A patent/BRPI0408467A/pt not_active Application Discontinuation
- 2004-03-08 PL PL04718300T patent/PL1611126T3/pl unknown
- 2004-03-08 EP EP04718300A patent/EP1611126B1/de not_active Expired - Lifetime
- 2004-03-08 CN CNA2004800085714A patent/CN1768056A/zh active Pending
- 2004-03-08 DK DK04718300.9T patent/DK1611126T3/da active
- 2004-03-08 PT PT04718300T patent/PT1611126E/pt unknown
- 2004-04-02 AR ARP040101116A patent/AR043834A1/es unknown
-
2005
- 2005-11-03 ZA ZA200508922A patent/ZA200508922B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1611126T3 (da) | 2010-01-18 |
| CA2520892C (en) | 2012-08-21 |
| EP1611126A1 (de) | 2006-01-04 |
| JP4740114B2 (ja) | 2011-08-03 |
| WO2004087692A1 (de) | 2004-10-14 |
| ATE446959T1 (de) | 2009-11-15 |
| PL377730A1 (pl) | 2006-02-06 |
| US7968551B2 (en) | 2011-06-28 |
| AU2004226279B2 (en) | 2010-10-28 |
| PT1611126E (pt) | 2010-01-29 |
| KR20050119673A (ko) | 2005-12-21 |
| CN1768056A (zh) | 2006-05-03 |
| MXPA05010483A (es) | 2005-11-16 |
| ZA200508922B (en) | 2007-02-28 |
| JP2006522034A (ja) | 2006-09-28 |
| DE10315285A1 (de) | 2004-10-14 |
| EP1611126B1 (de) | 2009-10-28 |
| CA2520892A1 (en) | 2004-10-14 |
| ES2335665T3 (es) | 2010-03-31 |
| PL1611126T3 (pl) | 2010-02-26 |
| AR043834A1 (es) | 2005-08-17 |
| DE502004010296D1 (de) | 2009-12-10 |
| US20060258680A1 (en) | 2006-11-16 |
| AU2004226279A1 (en) | 2004-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0316081A (pt) | Derivados de 2-piridona como inibidores de elastase de neutrófilo | |
| BRPI0416532A (pt) | 2-quinolinonas e 2-quinoxalinonas substituìdas por 6 como inibidores da poli(adp-ribose) polimerase | |
| BRPI0417571A (pt) | 2-quinolinonas e 2-quinoxalinonas substituìdas por 6-ciclohexil-alquila substituìda como inibidores da poli(adp-ribose) polimerase | |
| AP1753A (en) | Thiophene derivatives as antiviral agents for flavvivirus infection | |
| BRPI0409465A (pt) | derivados de carboxamida como agentes antidiabéticos | |
| BR0316386A (pt) | Benzoxazin-3-onas e seus derivados como inibidores de p13k | |
| BR0205889A (pt) | Pirazolopirimidinas como agentes tepapêuticos | |
| BRPI0509795A (pt) | composto ou um sal farmacologicamente aceitável do mesmo, composição farmacêutica, uso do composto ou sal farmacologicamente aceitável do mesmo, e, método para promover osteogênese, supressão de ressorção óssea e/ou melhoramento da densidade óssea | |
| ATE388958T1 (de) | 4'-c-substituierte 2-haloadenosinderivate | |
| BR0010555A (pt) | Inibidores de neuraminidases | |
| BRPI0410714B8 (pt) | derivados de quinazolina macrocíclicos, seu processo de preparação, composição farmacêutica que os compreende e uso | |
| BRPI0412347A (pt) | 2-aminofenil-4-fenilpiridinas como inibidores de quinase | |
| DE602004008098D1 (de) | Substituierte 2h-ä1,2,4ütriazoloä4,3-aüpyrazine als gsk-3-inhibitoren | |
| BR0317435A (pt) | Derivados de pirimidina para o tratamento do crescimento celular anormal | |
| BRPI0408353A (pt) | composto, composição farmacêutica, métodos para o tratamento de neoplasias suscetìveis e para o tratamento de infecções virais, e, uso de um composto | |
| BR0012697A (pt) | Inibidores da diferenciação de th2 | |
| BRPI0513672A (pt) | processo aperfeiçoado para a preparação de 2h-1-benzopiran-2metanol, (alfa). (alfa)' [iminobis (metileno)] bis [6-fluoro-3, 4-dihidro, [2r* [r* [r* (s*)]]]], composição farmacêutica, forma t1 amorfa, e processo para a preparação da forma t1 de hidrocloreto de nebivolol | |
| MY148988A (en) | Terphenyl derivatives for treatment of alzheimer's disease | |
| BRPI0507903A (pt) | derivados de quinazolina e composição farmacêutica compreendendo os mesmos | |
| BRPI0408467A (pt) | cromenonaindóis | |
| BRPI0414011A (pt) | naftalencarboxamidas e seus derivados úteis como novos agentes antiangiogênicos | |
| BR0212069A (pt) | Agentes antidiabéticos orais | |
| BRPI0406721A (pt) | Compostos condensados de furano | |
| BR0207408A (pt) | Azóis como inibidores de malonil-coa decarboxilase úteis como moduladores metabólicos | |
| BRPI0409105A (pt) | análogos de quinobenzoxazina substituìdos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |