BRPI0404635B8 - processo para a obtenção de esteróides seco derivados do ergostano - Google Patents

processo para a obtenção de esteróides seco derivados do ergostano

Info

Publication number
BRPI0404635B8
BRPI0404635B8 BRPI0404635A BRPI0404635A BRPI0404635B8 BR PI0404635 B8 BRPI0404635 B8 BR PI0404635B8 BR PI0404635 A BRPI0404635 A BR PI0404635A BR PI0404635 A BRPI0404635 A BR PI0404635A BR PI0404635 B8 BRPI0404635 B8 BR PI0404635B8
Authority
BR
Brazil
Prior art keywords
dry
ergostane
steroids
derived
water
Prior art date
Application number
BRPI0404635A
Other languages
English (en)
Inventor
Cláudia Fernandes Amaral Ana
Maria Ribeiro Ivone
Botelho Pereira Soares Milena
Ribeiro Dos Santos Ricardo
Coelho Barbosa Tomassini Therezinha
Original Assignee
Fundacao Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Oswaldo Cruz filed Critical Fundacao Oswaldo Cruz
Priority to BRPI0404635A priority Critical patent/BRPI0404635B8/pt
Priority to PCT/BR2005/000223 priority patent/WO2006045171A2/en
Publication of BRPI0404635A publication Critical patent/BRPI0404635A/pt
Publication of BRPI0404635B1 publication Critical patent/BRPI0404635B1/pt
Publication of BRPI0404635B8 publication Critical patent/BRPI0404635B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"processo para a obtenção de esteróides seco derivados do ergostano". a presente invenção refere-se a um processo de obtenção de esteróides seco derivados do ergostano, como as fisalinas, compreendendo as etapas de: (a) moagem de partes secas de planta(s) da família solanaceae; (b) tratamento das ditas partes de planta(s) da etapa (a) com solução salina de cloreto de sódio (tampão fisiológico) por um período de tempo apropriado; (c) filtração do soluto proveniente da etapa (b) e, então, particioná-lo em diclorometano ou solvente imiscível em água, como clorofórmio ou acetato de etila; (d) lavagem da fase orgânica resultante da etapa (c) com água destilada e posterior filtração em sulfato de magnésio anidro ou qualquer outro secante insolúvel em água; (e) evaporação da solução resultante da etapa (d) , fornecendo uma fração enriquecida em esteróides seco derivados do ergostano; (f) separação dos esteróides seco derivados do ergostano por cromatografia líquida de média pressão (mplc) e subseqüente caracterização espectroscópia.
BRPI0404635A 2004-10-25 2004-10-25 processo para a obtenção de esteróides seco derivados do ergostano BRPI0404635B8 (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0404635A BRPI0404635B8 (pt) 2004-10-25 2004-10-25 processo para a obtenção de esteróides seco derivados do ergostano
PCT/BR2005/000223 WO2006045171A2 (en) 2004-10-25 2005-10-25 Process for obtaining dry steroids derivative from ergostane

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0404635A BRPI0404635B8 (pt) 2004-10-25 2004-10-25 processo para a obtenção de esteróides seco derivados do ergostano

Publications (3)

Publication Number Publication Date
BRPI0404635A BRPI0404635A (pt) 2007-02-21
BRPI0404635B1 BRPI0404635B1 (pt) 2019-01-15
BRPI0404635B8 true BRPI0404635B8 (pt) 2021-05-25

Family

ID=36228134

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0404635A BRPI0404635B8 (pt) 2004-10-25 2004-10-25 processo para a obtenção de esteróides seco derivados do ergostano

Country Status (2)

Country Link
BR (1) BRPI0404635B8 (pt)
WO (1) WO2006045171A2 (pt)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61143324A (ja) * 1984-12-17 1986-07-01 Takeo Haneda 血圧、血糖改善食品
US20020103386A1 (en) * 1999-10-14 2002-08-01 Therezinha C. B. Tomassini Process for isolating physalins from plants and pharmaceutical compositions containing physalins

Also Published As

Publication number Publication date
WO2006045171A2 (en) 2006-05-04
WO2006045171A3 (en) 2007-10-04
BRPI0404635B1 (pt) 2019-01-15
BRPI0404635A (pt) 2007-02-21

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B21H Decision of lapse of a patent or of a certificate of addition of invention cancelled [chapter 21.8 patent gazette]

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