BRPI0207141B8 - processo para preparar compostos, uso de compostos, composição farmacêutica e método para tratamento de câncer - Google Patents
processo para preparar compostos, uso de compostos, composição farmacêutica e método para tratamento de câncerInfo
- Publication number
- BRPI0207141B8 BRPI0207141B8 BRPI0207141A BRPI0207141B8 BR PI0207141 B8 BRPI0207141 B8 BR PI0207141B8 BR PI0207141 A BRPI0207141 A BR PI0207141A BR PI0207141 B8 BRPI0207141 B8 BR PI0207141B8
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- pharmaceutical composition
- treating cancer
- preparing
- preparing compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
- C07C49/245—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings
- C07C49/248—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0207141-0 BRPI0207141B8 (pt) | 2002-11-28 | 2002-11-28 | processo para preparar compostos, uso de compostos, composição farmacêutica e método para tratamento de câncer |
PT37733649T PT1572614E (pt) | 2002-11-28 | 2003-11-28 | Processo para a preparação de 1,5-bis(4-hidroxi-3-metoxifenil)- penta-1,4-dien-3-ona |
JP2004554088A JP2006508149A (ja) | 2002-11-28 | 2003-11-28 | 抗腫瘍特性を有する1,5−ビス(4−ヒドロキシ−3−メトキシフェニル)−ペンタ−1,4−ジエン−3−オンおよび誘導体の新規な製造方法 |
EP03773364.9A EP1572614B1 (en) | 2002-11-28 | 2003-11-28 | Method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one |
ES03773364.9T ES2464268T3 (es) | 2002-11-28 | 2003-11-28 | Procedimiento para la preparaci�n de 1,5-bis(4-hidroxi-3-metoxi-fenil)-penta-1,4-dien-3-ona |
PCT/BR2003/000177 WO2004047716A2 (en) | 2002-11-28 | 2003-11-28 | New method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties |
US10/536,667 US7432401B2 (en) | 2002-11-28 | 2003-11-28 | Method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties |
AU2003283092A AU2003283092A1 (en) | 2002-11-28 | 2003-11-28 | New method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0207141-0 BRPI0207141B8 (pt) | 2002-11-28 | 2002-11-28 | processo para preparar compostos, uso de compostos, composição farmacêutica e método para tratamento de câncer |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0207141A BR0207141A (pt) | 2004-06-29 |
BRPI0207141B1 BRPI0207141B1 (pt) | 2019-04-16 |
BRPI0207141B8 true BRPI0207141B8 (pt) | 2021-05-25 |
Family
ID=67251474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0207141-0 BRPI0207141B8 (pt) | 2002-11-28 | 2002-11-28 | processo para preparar compostos, uso de compostos, composição farmacêutica e método para tratamento de câncer |
Country Status (8)
Country | Link |
---|---|
US (1) | US7432401B2 (pt) |
EP (1) | EP1572614B1 (pt) |
JP (1) | JP2006508149A (pt) |
AU (1) | AU2003283092A1 (pt) |
BR (1) | BRPI0207141B8 (pt) |
ES (1) | ES2464268T3 (pt) |
PT (1) | PT1572614E (pt) |
WO (1) | WO2004047716A2 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8841326B2 (en) | 2004-02-12 | 2014-09-23 | Stc.Unm | Therapeutic curcumin derivatives |
BRPI0602640B8 (pt) * | 2006-07-06 | 2021-05-25 | Anhanguera Educacional Ltda | métodos de obtenção de penta-1,4-dien-3-onas e de cicloexanonas substituídas e derivados com propriedades antitumorais e antiparasitárias, processo para preparar 1,5-bis-(aril)-penta-1,4-dien-3-onas alquiladas e aciladas, processo para preparar 4-nitro-3,5-diaril-cicloexanonas substituídas, processo para preparar 2,6-dibenzilideno-4-nitro-3,5-diaril-cicloexanonas substituídas, processo para preparar uma mistura formada por quantidades determinadas dos compostos (1,5-bis(4-hidróxi-3-metóxi-fenil)penta-1,4-dien-3-ona) e (1,5-bis(3-metóxi-4-acetóxi-fenil)penta-1,4-dien-3-ona), compostos e seus usos, composição farmacêutica, método terapêutico para tratamento dos cânceres e composição sinérgica |
CN103922911A (zh) * | 2014-04-17 | 2014-07-16 | 上海应用技术学院 | 一种(1e,4e)-1,5-二(邻溴间甲氧基苯基)-1,4-戊二烯酮化合物及合成方法 |
CN114478256B (zh) * | 2022-01-26 | 2024-02-23 | 安徽理工大学环境友好材料与职业健康研究院(芜湖) | 一种新型姜黄素衍生物的制备方法及其抗肝癌的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4521629A (en) * | 1984-06-29 | 1985-06-04 | American Cyanamid Company | Method for the preparation of 1,5-bis-aryl-1,4-pentadien-3-ones |
EP0398692B1 (en) * | 1989-05-17 | 1996-08-21 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | Alkoxyiminoacetamide derivatives and their use as fungicides |
JP2856838B2 (ja) * | 1990-04-30 | 1999-02-10 | 株式会社クラレ | ステロイド誘導体の製造方法 |
JP2921104B2 (ja) * | 1990-11-15 | 1999-07-19 | 東亞合成株式会社 | β,γ―不飽和アルケニル基置換フェノール類の製造方法 |
JPH07215957A (ja) * | 1994-02-03 | 1995-08-15 | Takeda Chem Ind Ltd | グリシジルエーテル類の製造法及びそのための連続製造装置 |
US6852248B1 (en) * | 1999-04-02 | 2005-02-08 | Hrl Laboratories, Llc | Dopants for liquid-crystal devices |
EP1242379A1 (en) * | 1999-12-03 | 2002-09-25 | Emory University | Curcumin analogues for treating cancer |
-
2002
- 2002-11-28 BR BRPI0207141-0 patent/BRPI0207141B8/pt not_active IP Right Cessation
-
2003
- 2003-11-28 EP EP03773364.9A patent/EP1572614B1/en not_active Expired - Lifetime
- 2003-11-28 ES ES03773364.9T patent/ES2464268T3/es not_active Expired - Lifetime
- 2003-11-28 US US10/536,667 patent/US7432401B2/en not_active Expired - Fee Related
- 2003-11-28 JP JP2004554088A patent/JP2006508149A/ja active Pending
- 2003-11-28 PT PT37733649T patent/PT1572614E/pt unknown
- 2003-11-28 WO PCT/BR2003/000177 patent/WO2004047716A2/en active Application Filing
- 2003-11-28 AU AU2003283092A patent/AU2003283092A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1572614A2 (en) | 2005-09-14 |
US20060128997A1 (en) | 2006-06-15 |
JP2006508149A (ja) | 2006-03-09 |
US7432401B2 (en) | 2008-10-07 |
ES2464268T3 (es) | 2014-06-02 |
AU2003283092A1 (en) | 2004-06-18 |
WO2004047716A2 (en) | 2004-06-10 |
WO2004047716A3 (en) | 2004-08-19 |
PT1572614E (pt) | 2014-04-03 |
AU2003283092A8 (en) | 2004-06-18 |
BR0207141A (pt) | 2004-06-29 |
EP1572614B1 (en) | 2013-12-25 |
BRPI0207141B1 (pt) | 2019-04-16 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B25C | Requirement related to requested transfer of rights |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) , FUNDACAO D |
|
B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) , FUNDACAO D |
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B25C | Requirement related to requested transfer of rights |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) , FUNDACAO D |
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B25B | Requested transfer of rights rejected |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) , FUNDACAO D |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B25C | Requirement related to requested transfer of rights |
Owner name: JOSA AGUSTA-N QUINCOCES SUA REZ (BR/SP) ; FUNDAA |
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B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) ; FUNDACAO D Free format text: ANULADA A PUBLICACAO CODIGO 25.3 NA RPI NO 2484 DE 14/08/2018 POR TER SIDO INDEVIDA. |
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B25D | Requested change of name of applicant approved |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) ; FUNDACAO D Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) ; FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO (BR/SP) ; ACADEMIA PAULISTA ANCHIETA LTDA. (BR/SP) |
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B25A | Requested transfer of rights approved |
Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) ; FUNDACAO D Owner name: JOSE AGUSTIN QUINCOCES SUAREZ (BR/SP) ; FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO (BR/SP) ; ANHANGUERA EDUCACIONAL LTDA. (BR/SP) |
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B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 16/04/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 16/04/2019, OBSERVADAS AS CONDICOES LEGAIS |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/11/2002 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 28/11/2022 |