BRPI0107761A - dispositivo osmótico, bem como método para fabricação do mesmo. - Google Patents

dispositivo osmótico, bem como método para fabricação do mesmo.

Info

Publication number
BRPI0107761A
BRPI0107761A BRPI0107761A BRPI0107761A BRPI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A BR PI0107761 A BRPI0107761 A BR PI0107761A
Authority
BR
Brazil
Prior art keywords
osmotic device
release
active agent
manufacturing
well
Prior art date
Application number
BRPI0107761A
Other languages
English (en)
Inventor
Joaquina Faour
Original Assignee
Osmotica Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osmotica Corp filed Critical Osmotica Corp
Publication of BRPI0107761A publication Critical patent/BRPI0107761A/pt
Publication of BRPI0107761B1 publication Critical patent/BRPI0107761B1/pt
Publication of BRPI0107761B8 publication Critical patent/BRPI0107761B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

"dispositivo osmótico que tem uma passagem pré-formada que aumenta de tamanho". a presente invenção provê um dispositivo osmótico simples e melhorado (1), que é capaz de prover uma liberação controlada de agente ativo contido no núcleo (4) através de uma passagem pré-formada (5) para um ambiente de uso. a passagem pré-formada (5) aumenta de tamanho durante o uso do dispositivo osmótico (1), desse modo aumentando a taxa de liberação do agente ativo, permitindo a liberação de partículas grandes contendo um agente ativo, e permitindo a liberação de agentes ativos que são substancialmente insolúveis no ambiente de uso.
BRPI0107761-9 2000-01-21 2001-01-08 dispositivo osmótico, bem como método para fabricação do mesmo. BRPI0107761B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17742700P 2000-01-21 2000-01-21
US09/728,859 US6599284B2 (en) 2000-01-21 2000-11-30 Osmotic device having a preformed passageway that increases in size
PCT/US2001/000582 WO2001052819A1 (en) 2000-01-21 2001-01-08 Osmotic device having a preformed passageway that increases in size

Publications (3)

Publication Number Publication Date
BRPI0107761A true BRPI0107761A (pt) 2002-11-12
BRPI0107761B1 BRPI0107761B1 (pt) 2012-12-11
BRPI0107761B8 BRPI0107761B8 (pt) 2021-07-06

Family

ID=26873279

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0107761-9 BRPI0107761B8 (pt) 2000-01-21 2001-01-08 dispositivo osmótico, bem como método para fabricação do mesmo.

Country Status (14)

Country Link
US (1) US6599284B2 (pt)
EP (1) EP1248598B1 (pt)
AR (1) AR026148A1 (pt)
AT (1) ATE347881T1 (pt)
AU (1) AU2001227732A1 (pt)
BR (1) BRPI0107761B8 (pt)
CA (1) CA2395981C (pt)
DE (1) DE60125142T2 (pt)
DK (1) DK1248598T3 (pt)
ES (1) ES2277909T3 (pt)
MX (1) MXPA02007017A (pt)
PT (1) PT1248598E (pt)
UY (1) UY26546A1 (pt)
WO (1) WO2001052819A1 (pt)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131908A1 (en) * 2000-01-13 2002-09-19 George Benda Selective release apparatus for fluids
WO2002055009A1 (en) * 2001-01-12 2002-07-18 Sun Pharmaceutical Industries Limited Spaced drug delivery system
KR200249057Y1 (ko) * 2001-03-22 2001-10-19 김진환 뚜껑, 받침대에 합체된 하수역류. 악취방지 장치
DK1377276T3 (da) * 2001-04-10 2012-01-02 Sun Pharma Advanced Res Co Ltd Beregning af puls-frigivelsessammensætning
US7585283B2 (en) * 2001-07-12 2009-09-08 Given Imaging Ltd. Device and method for examining a body lumen
US7083578B2 (en) * 2001-07-12 2006-08-01 Given Imaging Ltd. Device and method for examining a body lumen
US20030175346A1 (en) * 2002-02-01 2003-09-18 Anne Billotte Osmotic delivery system
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
ITMI20020515A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema per il rilasco controllato di uno o piu' principi attivi
US8523788B2 (en) * 2002-07-11 2013-09-03 Given Imaging Ltd. Device, system and method for examining a body lumen
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7959946B2 (en) * 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8293799B2 (en) * 2003-12-29 2012-10-23 Osmotica Keresleedelmo és Szolgáltató KFT Osmotic device containing a venlafaxine salt and a salt having an ion in common
WO2004108067A2 (en) * 2003-04-03 2004-12-16 Sun Pharmaceutical Industries Limited Programmed drug delivery system
ATE512659T1 (de) 2003-04-24 2011-07-15 Jagotec Ag Tablette mit verzögerter wirkstofffreigabe und bestimmter formgeometrie
WO2004093850A1 (en) * 2003-04-24 2004-11-04 Jagotec Ag Tablet with coloured core
US8029822B2 (en) * 2003-05-22 2011-10-04 Osmotica Kereskedelmi és Seolgáltató KFT Rupturing controlled release device having a preformed passageway
UY28326A1 (es) * 2003-05-22 2004-06-30 Osmotica Argentina S A Dispositivo de ruptura de liberacion controlada con un pasaje preformado
US20060177507A1 (en) * 2003-05-22 2006-08-10 Joaquina Faour Controlled release device containing lercanidipine
JP2007503389A (ja) * 2003-08-22 2007-02-22 アルザ・コーポレーシヨン 長期間にわたるトピラメートの段階的送達
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
WO2005056708A2 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
SE0401031D0 (sv) * 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
US8574626B2 (en) 2004-12-03 2013-11-05 Osmotica Kereskedelmi és Szolgáltató KFT Osmotic device containing amantadine and an osmotic salt
US8252331B2 (en) * 2004-12-03 2012-08-28 Osmotica Kereskedelmi és Szolgáltató, KFT Osmotic device containing amantadine and an osmotic salt
AR053986A1 (es) 2004-12-03 2007-05-30 Osmotica Pharmaceutical Argent Dispositivo osmotico que contiene amantadina y una sal osmotica
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
NZ561375A (en) 2005-06-27 2011-06-30 Biovail Lab Int Srl Bupropion hydrobromide, and crystalline forms, compositions, and uses of this compound
US20070003624A1 (en) * 2005-06-29 2007-01-04 Shanbhag Anant R Semi-permeable compositions providing reduced drying time for osmotic dosage forms
KR101568660B1 (ko) 2006-05-02 2015-11-12 프로테우스 디지털 헬스, 인코포레이티드 환자 주문형 치료법
US7772390B1 (en) 2006-07-18 2010-08-10 The Regents Of The University Of California Lipid mediated nucleic acid synthesis
SI2049123T1 (sl) 2006-08-03 2013-04-30 Horizon Pharma Ag Zdravljenje revmatoznih bolezni z zadržanim sproščanjem glukokortikoida
EP2083680B1 (en) 2006-10-25 2016-08-10 Proteus Digital Health, Inc. Controlled activation ingestible identifier
EP2069004A4 (en) 2006-11-20 2014-07-09 Proteus Digital Health Inc PERSONAL HEALTH SIGNAL RECEIVERS WITH ACTIVE SIGNAL PROCESSING
US8858432B2 (en) 2007-02-01 2014-10-14 Proteus Digital Health, Inc. Ingestible event marker systems
EP2111661B1 (en) * 2007-02-14 2017-04-12 Proteus Digital Health, Inc. In-body power source having high surface area electrode
US8932221B2 (en) 2007-03-09 2015-01-13 Proteus Digital Health, Inc. In-body device having a multi-directional transmitter
WO2008112578A1 (en) 2007-03-09 2008-09-18 Proteus Biomedical, Inc. In-body device having a deployable antenna
US8540632B2 (en) 2007-05-24 2013-09-24 Proteus Digital Health, Inc. Low profile antenna for in body device
EP2229500A1 (en) * 2007-06-21 2010-09-22 Swelltec Limited Apparatus and method with hydrocarbon swellable and water swellable body
GB0711979D0 (en) * 2007-06-21 2007-08-01 Swelltec Ltd Method and apparatus
US20090004281A1 (en) * 2007-06-26 2009-01-01 Biovail Laboratories International S.R.L. Multiparticulate osmotic delivery system
US8637080B2 (en) * 2007-06-28 2014-01-28 Osmotica Kereskedelmi és Szolgáltató, KFT Rupturing controlled release device comprising a subcoat
ES2928197T3 (es) 2007-09-25 2022-11-16 Otsuka Pharma Co Ltd Dispositivo intracorpóreo con amplificación de señal de dipolo virtual
JP2011513865A (ja) 2008-03-05 2011-04-28 プロテウス バイオメディカル インコーポレイテッド マルチモード通信の摂取可能なイベントマーカーおよびシステム、ならびにそれを使用する方法
US20090312627A1 (en) * 2008-06-16 2009-12-17 Matott Laura A Radio-labeled ingestible capsule
ES2696984T3 (es) 2008-07-08 2019-01-21 Proteus Digital Health Inc Infraestructura de datos de marcadores de eventos de ingestión
WO2010015840A1 (en) * 2008-08-08 2010-02-11 Cipla Limited Osmotic delivery device with modified release
AU2009281876B2 (en) 2008-08-13 2014-05-22 Proteus Digital Health, Inc. Ingestible circuitry
US20100068152A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable particle or polymeric based final dosage form
US20100069821A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable medicament release-sites final dosage form
US20100068153A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo activatable final dosage form
US20100068275A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Personalizable dosage form
US20100068233A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Modifiable dosage form
US20100068254A1 (en) * 2008-09-16 2010-03-18 Mahalaxmi Gita Bangera Modifying a medicament availability state of a final dosage form
US20100069887A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multiple chamber ex vivo adjustable-release final dosage form
US20100068266A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo-modifiable multiple-release state final dosage form
US20100068235A1 (en) * 2008-09-16 2010-03-18 Searete LLC, a limited liability corporation of Deleware Individualizable dosage form
SG196787A1 (en) 2009-01-06 2014-02-13 Proteus Digital Health Inc Ingestion-related biofeedback and personalized medical therapy method and system
TWI602561B (zh) 2009-01-06 2017-10-21 波提亞斯數位康健公司 醫藥劑量傳送系統
CA2749646A1 (en) * 2009-01-26 2010-07-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of asthma
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
US8540664B2 (en) 2009-03-25 2013-09-24 Proteus Digital Health, Inc. Probablistic pharmacokinetic and pharmacodynamic modeling
SG10201810784SA (en) 2009-04-28 2018-12-28 Proteus Digital Health Inc Highly Reliable Ingestible Event Markers And Methods For Using The Same
EP2432458A4 (en) * 2009-05-12 2014-02-12 Proteus Digital Health Inc ACCEPTABLE EVENT MARKER WITH SUGAR COMPONENT
TWI517050B (zh) 2009-11-04 2016-01-11 普羅托斯數位健康公司 供應鏈管理之系統
US8945010B2 (en) 2009-12-23 2015-02-03 Covidien Lp Method of evaluating constipation using an ingestible capsule
BR112012025650A2 (pt) 2010-04-07 2020-08-18 Proteus Digital Health, Inc. dispositivo ingerível miniatura
TWI557672B (zh) 2010-05-19 2016-11-11 波提亞斯數位康健公司 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置
EP2642983A4 (en) 2010-11-22 2014-03-12 Proteus Digital Health Inc DEVICE INGREABLE WITH PHARMACEUTICAL PRODUCT
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
UA118745C2 (uk) 2011-07-21 2019-03-11 Протеус Діджитал Хелс, Інк. Пристрій, система та спосіб мобільного зв'язку
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
KR20150038038A (ko) 2012-07-23 2015-04-08 프로테우스 디지털 헬스, 인코포레이티드 섭취 가능한 부품을 포함하는 섭취 가능한 이벤트 마커를 제조하기 위한 기술
CN102871982B (zh) * 2012-10-16 2014-09-10 中国科学院上海药物研究所 一种药物渗透泵制剂
KR101565013B1 (ko) 2012-10-18 2015-11-02 프로테우스 디지털 헬스, 인코포레이티드 통신 디바이스를 위한 전원에서 전력 소비 및 브로드캐스트 전력을 적응적으로 최적화시키는 장치, 시스템 및 방법
JP2016508529A (ja) 2013-01-29 2016-03-22 プロテウス デジタル ヘルス， インコーポレイテッド 高度に膨張可能なポリマーフィルムおよびこれを含む組成物
US11744481B2 (en) 2013-03-15 2023-09-05 Otsuka Pharmaceutical Co., Ltd. System, apparatus and methods for data collection and assessing outcomes
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
JP6392355B2 (ja) * 2013-09-13 2018-09-19 アール．ピー．シェーラー テクノロジーズ、エルエルシー ペレット包含錠剤
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
US20150307754A1 (en) * 2014-04-28 2015-10-29 Celanese Acetate Llc Adhesives that include highly-plasticized cellulose esters and methods and articles relating thereto
US10172800B2 (en) 2015-02-20 2019-01-08 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form with enhanced pharmacokinetics
US9579289B2 (en) 2015-02-20 2017-02-28 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US10987328B2 (en) 2015-02-20 2021-04-27 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US10300032B2 (en) 2015-02-20 2019-05-28 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
TWI728155B (zh) 2016-07-22 2021-05-21 日商大塚製藥股份有限公司 可攝食事件標示器之電磁感測及偵測
CN109963499B (zh) 2016-10-26 2022-02-25 大冢制药株式会社 用于制造具有可吸收事件标记器的胶囊的方法
US10213394B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US10213393B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság Composition and method for treating neurological disease
US20190247331A1 (en) 2018-02-15 2019-08-15 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US5082668A (en) * 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4615698A (en) * 1984-03-23 1986-10-07 Alza Corporation Total agent osmotic delivery system
US4627851A (en) * 1984-10-26 1986-12-09 Alza Corporation Colonic-therapeutic delivery system
US4685918A (en) * 1985-02-01 1987-08-11 Merck & Co., Inc. Lipid osmotic pump
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4857330A (en) * 1986-04-17 1989-08-15 Alza Corporation Chlorpheniramine therapy
US4960416A (en) * 1986-04-30 1990-10-02 Alza Corporation Dosage form with improved delivery capability
US4743248A (en) * 1986-08-11 1988-05-10 Alza Corporation Dosage form for delivering acid sensitive beneficial agent
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
ATE124864T1 (de) * 1989-03-10 1995-07-15 Yamanouchi Pharma Co Ltd Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen.
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
US5273752A (en) 1989-07-18 1993-12-28 Alza Corporation Controlled release dispenser comprising beneficial agent
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5057321A (en) * 1990-06-13 1991-10-15 Alza Corporation Dosage form comprising drug and maltodextrin
US5240713A (en) 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5266332A (en) * 1991-12-06 1993-11-30 Alza Corporation Method for administering anti-Parkinson drug
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
DE69425453T2 (de) * 1993-04-23 2001-04-12 Novartis Ag, Basel Wirkstoffabgabevorrichtung mit gesteuerter Freigabe
US5914131A (en) * 1994-07-07 1999-06-22 Alza Corporation Hydromorphone therapy
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif
US5718700A (en) * 1994-09-20 1998-02-17 Alza Corporation Exit means in dosage form
US5558879A (en) * 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
AU7706598A (en) * 1997-05-30 1998-12-30 Laboratorios Phoenix U.S.A., Inc. Multi-layered osmotic device
US6514530B2 (en) * 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
ES2213404T3 (es) * 1998-12-17 2004-08-16 Alza Corporation Transformacion de capsulas de gelatina rellenas de liquido en sistemas de liberacion controlada mediante multiples revestimientos.

Also Published As

Publication number Publication date
AU2001227732A1 (en) 2001-07-31
DE60125142D1 (de) 2007-01-25
BRPI0107761B1 (pt) 2012-12-11
WO2001052819A1 (en) 2001-07-26
ATE347881T1 (de) 2007-01-15
MXPA02007017A (es) 2004-03-10
PT1248598E (pt) 2007-03-30
AR026148A1 (es) 2003-01-29
BRPI0107761B8 (pt) 2021-07-06
EP1248598B1 (en) 2006-12-13
CA2395981A1 (en) 2001-07-26
EP1248598A4 (en) 2004-01-21
DK1248598T3 (da) 2007-03-05
CA2395981C (en) 2008-07-08
UY26546A1 (es) 2001-10-25
US6599284B2 (en) 2003-07-29
ES2277909T3 (es) 2007-08-01
EP1248598A1 (en) 2002-10-16
DE60125142T2 (de) 2007-10-25
US20020099361A1 (en) 2002-07-25

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