BR9915712A - Usos de ciclobutilalquilaminas substituìdas com arila, e da sibutramina e seus enanciÈmeros e seus sais farmaceuticamente apropriados, e, método para o tratamento da incontinência urinária - Google Patents
Usos de ciclobutilalquilaminas substituìdas com arila, e da sibutramina e seus enanciÈmeros e seus sais farmaceuticamente apropriados, e, método para o tratamento da incontinência urináriaInfo
- Publication number
- BR9915712A BR9915712A BR9915712-8A BR9915712A BR9915712A BR 9915712 A BR9915712 A BR 9915712A BR 9915712 A BR9915712 A BR 9915712A BR 9915712 A BR9915712 A BR 9915712A
- Authority
- BR
- Brazil
- Prior art keywords
- aryl
- treatment
- cyclobutylalkylamines
- substituted
- urinary incontinence
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- 206010046543 Urinary incontinence Diseases 0.000 title abstract 2
- 125000003118 aryl group Chemical group 0.000 title 1
- UNAANXDKBXWMLN-UHFFFAOYSA-N sibutramine Chemical compound C=1C=C(Cl)C=CC=1C1(C(N(C)C)CC(C)C)CCC1 UNAANXDKBXWMLN-UHFFFAOYSA-N 0.000 title 1
- 229960004425 sibutramine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"USOS DE CICLOBUTILALQUILAMINAS SUBSTITUìDAS COM ARILA, E DA SIBUTRAMINA E SEUS ENANCIÈMEROS E SEUS SAIS FARMACEUTICAMENTE APROPRIADOS". Ciclobutilalquilaminas substituídas com arila e seus sais farmaceuticamente apropriados podem ser usadas para o tratamento da incontinência urinária.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/201,309 US6046242A (en) | 1998-11-27 | 1998-11-27 | Use of aryl-substituted cyclobutylalkylamines for treating urinary incontinence |
PCT/EP1999/008879 WO2000032182A1 (en) | 1998-11-27 | 1999-11-19 | The use of aryl-substituted cyclobutylalkylamines for treating urinary incontinence |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9915712A true BR9915712A (pt) | 2001-08-21 |
Family
ID=22745329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9915712-8A BR9915712A (pt) | 1998-11-27 | 1999-11-19 | Usos de ciclobutilalquilaminas substituìdas com arila, e da sibutramina e seus enanciÈmeros e seus sais farmaceuticamente apropriados, e, método para o tratamento da incontinência urinária |
Country Status (16)
Country | Link |
---|---|
US (1) | US6046242A (pt) |
EP (1) | EP1133288A1 (pt) |
JP (1) | JP2002531400A (pt) |
KR (1) | KR20010086452A (pt) |
CN (1) | CN1330541A (pt) |
AU (1) | AU1506400A (pt) |
BR (1) | BR9915712A (pt) |
CA (1) | CA2352199A1 (pt) |
CZ (1) | CZ20011856A3 (pt) |
HK (1) | HK1042431A1 (pt) |
HU (1) | HUP0104514A2 (pt) |
IL (1) | IL143304A0 (pt) |
MX (1) | MXPA01005255A (pt) |
NO (1) | NO20012569L (pt) |
WO (1) | WO2000032182A1 (pt) |
ZA (1) | ZA200104117B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6974838B2 (en) * | 1998-08-24 | 2005-12-13 | Sepracor Inc. | Methods of treating or preventing pain using sibutramine metabolites |
US6476078B2 (en) * | 1999-08-11 | 2002-11-05 | Sepracor, Inc. | Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction |
US6399826B1 (en) * | 1999-08-11 | 2002-06-04 | Sepracor Inc. | Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain |
US6610887B2 (en) | 2001-04-13 | 2003-08-26 | Sepracor Inc. | Methods of preparing didesmethylsibutramine and other sibutramine derivatives |
US20050131074A1 (en) * | 2003-08-04 | 2005-06-16 | Beckman Kristen M. | Methods for treating metabolic syndrome |
KR100830002B1 (ko) * | 2005-01-06 | 2008-05-15 | 씨제이제일제당 (주) | 시부트라민의 무기산염 |
CN101555214B (zh) | 2008-04-08 | 2012-07-11 | 北京嘉事联博医药科技有限公司 | 苯基环丁基酰胺衍生物及其光学异构体、制备方法和用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA821577B (en) * | 1981-04-06 | 1983-03-30 | Boots Co Plc | Therapeutic agents |
IE61928B1 (en) * | 1988-11-29 | 1994-11-30 | Boots Co Plc | Treatment of obesity |
EP0647134A4 (en) * | 1992-06-23 | 1997-07-30 | Sepracor Inc | METHODS AND COMPOSITIONS USED TO TREAT DEPRESSION AND OTHER CONDITIONS WITH OPTICALLY PURE SIBUTRAMINE (-). |
AU4542993A (en) * | 1992-06-23 | 1994-01-24 | Sepracor, Inc. | Methods and compositions for treating depression and other disorders using optically pure (+) sibutramine |
TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
DE19518988A1 (de) * | 1995-05-29 | 1996-12-05 | Basf Ag | Verwendung arylsubstituierter Cyclobutylalkylamine zur Behandlung der Fettleibigkeit |
ES2145977T3 (es) * | 1995-08-16 | 2000-07-16 | Lilly Co Eli | Potenciacion de la respuesta de la serotonina. |
GB9619961D0 (en) * | 1996-09-25 | 1996-11-13 | Knoll Ag | Medical treatment |
-
1998
- 1998-11-27 US US09/201,309 patent/US6046242A/en not_active Expired - Fee Related
-
1999
- 1999-11-19 CN CN99814527A patent/CN1330541A/zh active Pending
- 1999-11-19 JP JP2000584878A patent/JP2002531400A/ja active Pending
- 1999-11-19 EP EP99957316A patent/EP1133288A1/en not_active Withdrawn
- 1999-11-19 HU HU0104514A patent/HUP0104514A2/hu unknown
- 1999-11-19 AU AU15064/00A patent/AU1506400A/en not_active Abandoned
- 1999-11-19 BR BR9915712-8A patent/BR9915712A/pt not_active IP Right Cessation
- 1999-11-19 MX MXPA01005255A patent/MXPA01005255A/es unknown
- 1999-11-19 IL IL14330499A patent/IL143304A0/xx unknown
- 1999-11-19 CA CA002352199A patent/CA2352199A1/en not_active Abandoned
- 1999-11-19 CZ CZ20011856A patent/CZ20011856A3/cs unknown
- 1999-11-19 KR KR1020017006608A patent/KR20010086452A/ko not_active Application Discontinuation
- 1999-11-19 WO PCT/EP1999/008879 patent/WO2000032182A1/en not_active Application Discontinuation
-
2001
- 2001-05-21 ZA ZA200104117A patent/ZA200104117B/xx unknown
- 2001-05-25 NO NO20012569A patent/NO20012569L/no not_active Application Discontinuation
-
2002
- 2002-04-30 HK HK02103202.6A patent/HK1042431A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200104117B (en) | 2002-09-25 |
WO2000032182A1 (en) | 2000-06-08 |
MXPA01005255A (es) | 2003-06-06 |
HK1042431A1 (zh) | 2002-08-16 |
IL143304A0 (en) | 2002-04-21 |
AU1506400A (en) | 2000-06-19 |
CA2352199A1 (en) | 2000-06-08 |
KR20010086452A (ko) | 2001-09-12 |
NO20012569L (no) | 2001-07-25 |
NO20012569D0 (no) | 2001-05-25 |
HUP0104514A2 (en) | 2002-08-28 |
US6046242A (en) | 2000-04-04 |
EP1133288A1 (en) | 2001-09-19 |
CN1330541A (zh) | 2002-01-09 |
JP2002531400A (ja) | 2002-09-24 |
CZ20011856A3 (cs) | 2002-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A, 5A, 6A, 7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007. |