BR9915323A - Derivados pirimidina e processos para sua preparação - Google Patents

Derivados pirimidina e processos para sua preparação

Info

Publication number
BR9915323A
BR9915323A BR9915323-8A BR9915323A BR9915323A BR 9915323 A BR9915323 A BR 9915323A BR 9915323 A BR9915323 A BR 9915323A BR 9915323 A BR9915323 A BR 9915323A
Authority
BR
Brazil
Prior art keywords
processes
preparation
pyrimidine derivatives
derivatives
ingredient
Prior art date
Application number
BR9915323-8A
Other languages
English (en)
Inventor
Jong Wook Lee
Bong Yong Lee
Chang Seop Kim
Seung Kyu Lee
Song Jin Lee
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of BR9915323A publication Critical patent/BR9915323A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS PIRIMIDINA E PROCESSOS PARA SUA PREPARAçãO" A presente invenção refere-se a novos derivados pirimidina e a sais farmaceuticamente aceitáveis não-tóxicos dos mesmos, que possuem uma excelente atividade inibidora contra secreção de ácido gástrico, uma composição farmacêutica contendo os mesmos como ingrediente ativo e a um processo para preparação dos mesmos.
BR9915323-8A 1998-11-17 1999-11-09 Derivados pirimidina e processos para sua preparação BR9915323A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980049164A KR100272471B1 (ko) 1998-11-17 1998-11-17 신규의 피리미딘 유도체 및 그의 제조방법
PCT/KR1999/000669 WO2000029403A1 (en) 1998-11-17 1999-11-09 Novel pyrimidine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
BR9915323A true BR9915323A (pt) 2001-08-07

Family

ID=36201265

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915323-8A BR9915323A (pt) 1998-11-17 1999-11-09 Derivados pirimidina e processos para sua preparação

Country Status (17)

Country Link
US (1) US6545008B1 (pt)
EP (1) EP1131312B1 (pt)
JP (1) JP2002530280A (pt)
KR (1) KR100272471B1 (pt)
CN (1) CN1159312C (pt)
AT (1) ATE307809T1 (pt)
AU (1) AU762098B2 (pt)
BR (1) BR9915323A (pt)
CA (1) CA2351644A1 (pt)
DE (1) DE69927997T2 (pt)
ES (1) ES2251234T3 (pt)
HK (1) HK1041000B (pt)
HU (1) HUP0104533A3 (pt)
MX (1) MXPA01004457A (pt)
RU (1) RU2236407C2 (pt)
TR (1) TR200101388T2 (pt)
WO (1) WO2000029403A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0110338D0 (en) * 2001-04-27 2001-06-20 Sb Pharmco Inc Novel processes
WO2005009980A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
WO2005041961A1 (en) 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
JP5802898B2 (ja) 2009-07-09 2015-11-04 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
PE20151413A1 (es) 2012-11-21 2015-10-23 Ptc Therapeutics Inc Inhibidores de bmi-1 de pirimidina inversa sustituida
AR093580A1 (es) 2013-08-30 2015-06-10 Ptc Therapeutics Inc Inhibidores bmi-1 de pirimidina sustituidos
EP3071553A4 (en) 2013-11-21 2017-08-02 PTC Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors
WO2020055544A2 (en) 2018-08-17 2020-03-19 Ptc Therapeutics, Inc. Method for treating pancreatic cancer

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
FR2640582B1 (fr) 1988-12-21 1991-08-16 Gerard Megret Procede d'habillage d'elements de boites montees et installation pour la mise en oeuvre de ce procede
TR25912A (tr) 1989-03-22 1993-11-01 Ciba Geigy Ag 2-ANILIN-PRIMIDIN TüREVLERI BU MADDELERINELDE EDIL MELERI VE ZARARLILARA KARSI MüCADELEDE KULLANILMA- LARI
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
CA2095213A1 (en) 1990-11-06 1992-05-07 Jotham W. Coe Quinazoline derivatives for enhancing antitumor activity
EP0580753B1 (en) 1991-04-17 1995-03-01 Pfizer Inc. Pyrimidine derivatives for enhancing antitumor activity
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
EP0640599B1 (en) 1993-08-26 1998-03-04 Ono Pharmaceutical Co., Ltd. 4-Aminopyrimidine derivatives
WO1995010506A1 (en) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyl-n-arylpyrimidinamines and derivatives thereof
WO1996005177A1 (en) * 1994-08-13 1996-02-22 Yuhan Corporation Novel pyrimidine derivatives and processes for the preparation thereof
CN1097591C (zh) * 1996-05-04 2003-01-01 株式会社柳韩洋行 制备嘧啶衍生物的方法
HU226752B1 (en) * 1996-10-29 2009-09-28 Yuhan Corp Process for preparation of pyrimidine derivatives
IN188411B (pt) 1997-03-27 2002-09-21 Yuhan Corp

Also Published As

Publication number Publication date
HK1041000B (zh) 2004-12-31
HUP0104533A3 (en) 2003-01-28
ES2251234T3 (es) 2006-04-16
ATE307809T1 (de) 2005-11-15
MXPA01004457A (es) 2004-04-05
CA2351644A1 (en) 2000-05-25
DE69927997T2 (de) 2006-07-27
DE69927997D1 (de) 2005-12-01
US6545008B1 (en) 2003-04-08
HK1041000A1 (en) 2002-06-28
KR100272471B1 (ko) 2000-11-15
EP1131312B1 (en) 2005-10-26
CN1326453A (zh) 2001-12-12
TR200101388T2 (tr) 2001-10-22
CN1159312C (zh) 2004-07-28
AU762098B2 (en) 2003-06-19
AU1081200A (en) 2000-06-05
EP1131312A1 (en) 2001-09-12
HUP0104533A2 (hu) 2002-04-29
WO2000029403A1 (en) 2000-05-25
KR20000032633A (ko) 2000-06-15
RU2236407C2 (ru) 2004-09-20
JP2002530280A (ja) 2002-09-17

Similar Documents

Publication Publication Date Title
BR0214243A (pt) Derivado de sulfonamida processo para a preparação de um derivado de sulfonamida e seus sais fisiologicamente aceitáveis, composição farmacêutica e uso de um derivado de sulfonamida
BR9908545A (pt) Derivado de piperidina, processo para a preparação do mesmo, composto, processo para a preparação do mesmo, e, composição farmacêutica
BR0215312A (pt) Uso de um composto, método para inibir a aurora quinase em um animal de sangue quente, composto, composição farmacêutica, e, processo para a preparação de um composto
BR9808540A (pt) Composto, processo para a preparação do mesmo, composição farmacêutica e processo para preparação dos mesmos, uso de um composto, e, processo para produzir a imunossupressão
BR0017030B8 (pt) derivados de tiazolilamida, processo para sua preparação, composição farmacêutica que os compreende e uso dos mesmos
BR9910583A (pt) Aminotetralinas n-substituìdas como ligantes para o receptor de neuropeptìdeo y y5 úteis no tratamento de obesidade e outros distúrbios
BR0207294A (pt) Composto, processo para a preparação de um composto ou de um sal farmaceuticamente aceitável ou um éster hidrolisável in vivo dos mesmos, composição farmacêutica, uso de um composto ou de um sal farmaceuticamente aceitável ou um éster hidrolisável in vivo dos mesmos, e, método para a produção de um efeito inibitório do ciclo celular (antiproliferação celular) em um animal de sangue quente
BR0312464A (pt) Inibidores de tirosina quinases
SE0001899D0 (sv) New compounds
NO20022264L (no) Farmasoytisk blanding inneholdende tolterodin, samt anvendelse derav
DOP2002000512A (es) Sales de acido succinato de 5,7,14-triazatetraciclo [10.3.1.0² ¹¹.04,9] hexadeca-2 (11),3,5,7,9-pentaeno y composiciones farmaceuticas de las mismas
ATE202337T1 (de) Cyclopropylalkansäurederivate
BR9801150A (pt) Derivados de propanolamina, processos para a preparação deles, produtos farmacêuticos compreendendo esses compostos e uso dos mesmos.
PT839041E (pt) Sais de derivados de amidina e de inibidor de ciclooxigenase processo para a sua preparacao sua utilizacao como farmacos e composicoes farmaceuticas contendo os referidos sais
BR0314195A (pt) Derivados de piridina substituìda como agentes antitumorais
BR9915323A (pt) Derivados pirimidina e processos para sua preparação
BR0008302A (pt) Uso de um derivado de benzaldeìdo, derivado de benzaldeìdo, composição farmacêutica, e, processo para a fabricação da mesma
ES2191099T3 (es) Derivados de hidantoina como productos intermedios para principios activos farmaceuticos.
AU7270798A (en) Antithrombotic agents
ES2192789T3 (es) Derivados de hidrazono-benzazuleno, composiciones farmaceuticas y compuestos intermedios.
EP1027051A4 (en) ANTITHROMBOTIC AGENTS
CO4930262A1 (es) Producto farmaceutico cristalino, su preparacion y uso como sustancia terapeutica
PT989994E (pt) Derivados de estreptograminas, a sua preparacao e as composicoes que os contem
AU2003301513A1 (en) Cyclic bioisosters of purine system derivatives and a pharmaceutical composition based thereon
DK0805817T3 (da) Thiolderivater med metallopeptidaseinhiberende aktivitet

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DA 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1986 DE 27/03/2009.