BR9915139A - Método de inibir a hiperpermeabilidade vascular, e de inibir um processo ou estado fisiológico em um indivìduo - Google Patents

Método de inibir a hiperpermeabilidade vascular, e de inibir um processo ou estado fisiológico em um indivìduo

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Publication number
BR9915139A
BR9915139A BR9915139-1A BR9915139A BR9915139A BR 9915139 A BR9915139 A BR 9915139A BR 9915139 A BR9915139 A BR 9915139A BR 9915139 A BR9915139 A BR 9915139A
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BR
Brazil
Prior art keywords
inhibiting
tyrosine kinase
vascular hyperpermeability
individual
events
Prior art date
Application number
BR9915139-1A
Other languages
English (en)
Inventor
Lee D Arnold
Peter F Bousquet
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of BR9915139A publication Critical patent/BR9915139A/pt

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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Abstract

"MéTODO DE INIBIR A HIPERPERMEABILIDADE VASCULAR, E DE INIBIR UM PROCESSO OU ESTADO FISIOLóGICO EM UM INDIVìDUO" A hiperpermeabilidade vascular em indivíduos é um prelúdio para diversos eventos fisiológicos que são freq³entemente nocivos. Entre estes eventos está a formação de edema, diapedese, mudança transendotelial aberrante, extravasação, exsudação e efusão, deposição de matriz (freq³entemente com a proliferação estromal anormal) e hipotensão vascular. A hiperpermeabilidade vascular e os eventos subsequentes podem ser inibidos pela administração de um composto que inibe a atividade da enzima do receptor de tirosina cinase de VEGF conhecido como receptor de tirosina cinase de KDR. Os compostos administrados preferidos inibem seletivamente a função da tirosina cinase KDR mas não bloqueiam a atividade da tirosina cinase de Flt-1 que é um outro receptor de tirosina cinase de VEGF.
BR9915139-1A 1998-11-06 1999-11-03 Método de inibir a hiperpermeabilidade vascular, e de inibir um processo ou estado fisiológico em um indivìduo BR9915139A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10746298P 1998-11-06 1998-11-06
PCT/US1999/025903 WO2000027414A2 (en) 1998-11-06 1999-11-03 Inhibition of the formation of vascular hyperpermeability

Publications (1)

Publication Number Publication Date
BR9915139A true BR9915139A (pt) 2001-08-07

Family

ID=22316735

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915139-1A BR9915139A (pt) 1998-11-06 1999-11-03 Método de inibir a hiperpermeabilidade vascular, e de inibir um processo ou estado fisiológico em um indivìduo

Country Status (19)

Country Link
EP (1) EP1126842A2 (pt)
JP (1) JP2002529421A (pt)
KR (1) KR20010080952A (pt)
CN (1) CN1342077A (pt)
AR (1) AR023912A1 (pt)
AU (1) AU1908000A (pt)
BG (1) BG105476A (pt)
BR (1) BR9915139A (pt)
CA (1) CA2347916A1 (pt)
CO (1) CO5150183A1 (pt)
CZ (1) CZ20011564A3 (pt)
HU (1) HUP0104302A3 (pt)
ID (1) ID29063A (pt)
IL (1) IL142583A0 (pt)
NO (1) NO20012218L (pt)
PL (1) PL348163A1 (pt)
SK (1) SK5052001A3 (pt)
TR (1) TR200102278T2 (pt)
WO (1) WO2000027414A2 (pt)

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DK2284180T3 (en) 2003-03-03 2015-12-21 Dyax Corp Uses of peptides that specifically bind to the HGF receptor (cMET)
PT1626714E (pt) 2003-05-20 2007-08-24 Bayer Pharmaceuticals Corp Diarilureias para doenças mediadas por pdgfr
ES2297490T3 (es) 2003-07-23 2008-05-01 Bayer Pharmaceuticals Corporation Omega-carboxiarildifenilurea fluoro sustituida para el tratamiento y prevencion de enfermadades y afecciones.
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KR101565886B1 (ko) 2013-10-23 2015-11-05 전남대학교산학협력단 난소과자극증후군의 진단 방법 및 키트
CN114010788A (zh) 2014-08-22 2022-02-08 奥克兰联合服务有限公司 通道调节剂
CN106381330A (zh) * 2016-08-30 2017-02-08 张建华 一种检测交通性脑积水易感性的引物及试剂盒
KR102644938B1 (ko) * 2018-03-19 2024-03-07 주식회사 파멥신 항-vegfr-2 항체
CN109718253B (zh) * 2019-01-16 2021-09-24 中国人民解放军总医院 一种代谢产生组胺的菌在预防或治疗高原病中的用途

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AU1908000A (en) 2000-05-29
KR20010080952A (ko) 2001-08-25
EP1126842A2 (en) 2001-08-29
NO20012218L (no) 2001-06-18
CO5150183A1 (es) 2002-04-29
HUP0104302A2 (hu) 2002-03-28
TR200102278T2 (tr) 2001-12-21
WO2000027414A3 (en) 2000-09-08
CN1342077A (zh) 2002-03-27
CA2347916A1 (en) 2000-05-18
WO2000027414A2 (en) 2000-05-18
JP2002529421A (ja) 2002-09-10
AR023912A1 (es) 2002-09-04
BG105476A (en) 2002-02-28
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