BR9914490A - Preparação de vacina contendo saponina - Google Patents

Preparação de vacina contendo saponina

Info

Publication number
BR9914490A
BR9914490A BR9914490-5A BR9914490A BR9914490A BR 9914490 A BR9914490 A BR 9914490A BR 9914490 A BR9914490 A BR 9914490A BR 9914490 A BR9914490 A BR 9914490A
Authority
BR
Brazil
Prior art keywords
preparation
vaccine
vaccine containing
adjuvant
containing saponin
Prior art date
Application number
BR9914490-5A
Other languages
English (en)
Inventor
Haruki Yamada
Hiroaki Kiyohara
Takayuri Nagai
Takeshiyabe
Chikara Aizawa
Yuuziro Suzuki
Eizaburu Susa
Toshiokato
Takashi Nagamine
Original Assignee
Kitasato Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Inst filed Critical Kitasato Inst
Publication of BR9914490A publication Critical patent/BR9914490A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)

Abstract

Patente de Invenção: "PREPARAçãO DE VACINA CONTENDOSAPONINA". A presente invenção provê um adjuvantecompreendendo, como um ingrediente ativo, um composto desaponina tendo, como a sua estrutura esqueletal, um esqueleto depresenegenina substituído com um resíduo de açúcar substituídoou não-substituído na posição 28, e provê a preparação de vacinacompreendendo o adjuvante. Por exemplo, estímulo imunológicosuficiente pode ser conseguido mesmo na inoculação intranasalatravés de utilização da saponina tendo a estrutura mostradaabaixo.
BR9914490-5A 1998-09-14 1999-09-14 Preparação de vacina contendo saponina BR9914490A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25978398 1998-09-14
PCT/JP1999/005019 WO2000015257A1 (fr) 1998-09-14 1999-09-14 Preparations vaccinales contenant des saponines

Publications (1)

Publication Number Publication Date
BR9914490A true BR9914490A (pt) 2001-10-30

Family

ID=17338927

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914490-5A BR9914490A (pt) 1998-09-14 1999-09-14 Preparação de vacina contendo saponina

Country Status (7)

Country Link
EP (1) EP1121937A4 (pt)
KR (1) KR20010075068A (pt)
AU (1) AU764052B2 (pt)
BR (1) BR9914490A (pt)
CA (1) CA2344336A1 (pt)
TW (1) TW586935B (pt)
WO (1) WO2000015257A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2420601A1 (en) 2000-08-31 2003-02-26 The Kitasato Institute Vaccine preparation containing fatty acid as component
BR0312273A (pt) * 2002-07-10 2005-04-26 Akzo Nobel Nv Composição imunogênica, vacina, método para a preparação da mesma, e, uso de uma composição imunogênica
WO2006046674A1 (ja) * 2004-10-25 2006-05-04 Chugai Seiyaku Kabushiki Kaisha Ｃ型肝炎ウイルス感染症の予防および治療剤
CN101260138B (zh) * 2008-03-24 2011-10-19 成都普思生物科技有限公司 一种远志酸和远志皂苷元的高效分离提纯方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583112A (en) * 1987-05-29 1996-12-10 Cambridge Biotech Corporation Saponin-antigen conjugates and the use thereof
JPH08133948A (ja) * 1994-11-07 1996-05-28 Shiseido Co Ltd 皮膚外用剤
KR0184779B1 (ko) * 1995-04-13 1999-04-01 성재갑 퀼라야 사포나리아 몰리나로부터 분리정제된 사포닌 변이체, 이의 분리정제 방법 및 이를 함유하는 백신 제형
US6241995B1 (en) * 1997-08-08 2001-06-05 University Of Saskatchewan Polygala senega compositions and methods of use

Also Published As

Publication number Publication date
KR20010075068A (ko) 2001-08-09
CA2344336A1 (en) 2000-03-23
EP1121937A4 (en) 2002-10-23
AU5650999A (en) 2000-04-03
WO2000015257A1 (fr) 2000-03-23
AU764052B2 (en) 2003-08-07
EP1121937A1 (en) 2001-08-08
TW586935B (en) 2004-05-11

Similar Documents

Publication Publication Date Title
BR0108893A (pt) Composição farmacêutica, composto e processo de preparação de compostos
IT8720621A0 (it) Formulazioni di steroide in soluzione acquosa per somministrazione nasale.
DK0695171T3 (da) Lyosfærer indeholdende gonadotropin
BR0110767A (pt) Derivados de piperidina farmaceuticamente ativos, em particular como moduladores da atividade de receptor de quimiocina
BR0214469A (pt) 17alfa-alquil-17beta-óxi-estratrienos e produtos intermediários para sua preparação, aplicação dos 17alfa-alquil-17beta-óxi-estratrienos para a preparação de medicamentos bem como preparações farmacêuticas
ATE401093T1 (de) Extrakte, wirkstoffe und pharmazeutische präparate mit antidiabetischen eigenschaften und ihre verwendung
CA2333601A1 (en) Surfactant for use in external preparations for skin and external preparation for skin containing the same
SE8804570L (sv) Ciclosporinkristallform, foerfarande foer dess framstaellning, farmaceutiska kompositioner innehaallande densamma samt dess anvaendning
IT8521088A0 (it) Procedimento per la preparazione di 1,2-difluoroetilene e 1-cloro-1,2-difluoro-etilene.
FR2621818B1 (fr) Medicament comprenant l'association de polymixine b, de netilmicine et d'amphotericine b administre par vaporisation
BR9914490A (pt) Preparação de vacina contendo saponina
NZ220418A (en) A pharmaceutical composition adapted for g.i. resorption comprising a polypeptide and a monosaccharide or sugar alcohol and/or a polyoxylakylene ether
BR9813810B1 (pt) surfactante baseado em um orto éster, a sua preparação e o seu uso.
DK539087D0 (da) 4,5-dihydro- og 4,5,6,7-tetrahydro-pyrazolooe1,5-aaapyrimidiner, fremgangsmaader til deres fremstilling samt deres anvendelse som laegemidler
IT1231509B (it) Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
DK135988D0 (da) 2,5-dihydropyrroler, fremgangsmaader til deres fremstilling samt deres anvendelse som herbicider
PA8449301A1 (es) Composiciones farmaceuticas
DK401988A (da) 11-substituerede 5-aryl-5h,11h-pyrrolo(2,1-c)-(1,4)benzoxazepiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler
DK197190D0 (da) Vandige, enzymholdige, flydende formuleringer
ES2086409T3 (es) Imidazolinas sustituidas en posicion 2 y preparacion y uso de las mismas.
CO5070673A1 (es) Composiciones farmaceuticas en forma de solucion estable que comprenden (1s,4r)-cis-4-(2-amino-6-(ciclopropilamino)-9h -purin-9-il)-2-ciclopenteno-1-metanol, un quelador de metal y un agente endulzante
BR9808126A (pt) Quinoxalinodionas
BR0009657A (pt) Corpo sìncrono com elemento de engate integrado
DE3865642D1 (de) Pharmazeutische zubereitung zur cholelitholyse.
BR0011498A (pt) Cicloiminodepsipeptìdeos e seu emprego para combater endoparasitas

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4A, 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.