BR9912988A - Composição farmacêutica e método de desenvolvimento de atividade neuronial em animal - Google Patents
Composição farmacêutica e método de desenvolvimento de atividade neuronial em animalInfo
- Publication number
- BR9912988A BR9912988A BR9912988-4A BR9912988A BR9912988A BR 9912988 A BR9912988 A BR 9912988A BR 9912988 A BR9912988 A BR 9912988A BR 9912988 A BR9912988 A BR 9912988A
- Authority
- BR
- Brazil
- Prior art keywords
- animal
- pharmaceutical composition
- neuronal activity
- development
- activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
<B>COMPOSIçãO FARMACêUTICA E MéTODO DE DESENVOLVIMENTO DE ATIVIDADE NEURONIAL EM ANIMAL<D> Esta invenção refere-se a composições farmacêuticas e métodos para desenvolver atividade neuronial usando carbamatos e uréias de moléculas pequenas, de baixo peso molecular, com afinidade para imunofilinas do tipo FKBP.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/139,672 US6242468B1 (en) | 1997-02-27 | 1998-08-25 | Carbamate and urea compositions and neurotrophic uses |
PCT/US1999/019261 WO2000010553A2 (en) | 1998-08-25 | 1999-08-24 | Carbamate and urea compositions and neurotrophic uses |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9912988A true BR9912988A (pt) | 2001-10-02 |
Family
ID=22487769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9912988-4A BR9912988A (pt) | 1998-08-25 | 1999-08-24 | Composição farmacêutica e método de desenvolvimento de atividade neuronial em animal |
Country Status (18)
Country | Link |
---|---|
US (1) | US6242468B1 (pt) |
EP (1) | EP1107757A2 (pt) |
JP (1) | JP2002523367A (pt) |
KR (1) | KR20010072992A (pt) |
CN (1) | CN1313767A (pt) |
AU (1) | AU5687999A (pt) |
BG (1) | BG105340A (pt) |
BR (1) | BR9912988A (pt) |
CA (1) | CA2341530A1 (pt) |
CZ (1) | CZ2001274A3 (pt) |
EA (1) | EA200100271A1 (pt) |
HU (1) | HUP0103166A3 (pt) |
IL (1) | IL140958A0 (pt) |
MX (1) | MXPA01001937A (pt) |
NO (1) | NO20010946L (pt) |
PL (1) | PL346759A1 (pt) |
SK (1) | SK2562001A3 (pt) |
WO (1) | WO2000010553A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7008960B1 (en) | 1999-03-02 | 2006-03-07 | Vitreo-Retinal Technologies, Inc. | Agents for intravitreal administration to treat or prevent disorders of the eye |
EP1196386A2 (en) * | 1999-07-06 | 2002-04-17 | Vertex Pharmaceuticals Incorporated | N-substituted glycine derivatives |
US20030199574A1 (en) * | 2000-03-02 | 2003-10-23 | Vitreo-Retinal Technologies, Inc. | Treatment of ophthalmic disorders using urea and urea derivatives |
US7977385B2 (en) * | 2000-03-02 | 2011-07-12 | Numoda Biotechnologies, Inc. | Agents for corneal or intrastromal administration to treat or prevent disorders of the eye |
US20050137124A1 (en) * | 2002-08-09 | 2005-06-23 | Vitreo-Retinal Technologies, Inc. A California Corporation | Agents for intravitreal administration to treat or prevent disorders of the eye |
EP1402888A1 (en) * | 2002-09-18 | 2004-03-31 | Jerini AG | The use of substituted carbocyclic compounds as rotamases inhibitors |
US20050197356A1 (en) * | 2004-03-02 | 2005-09-08 | Wyeth | Non-immunosuppressive immunophilin ligands as neuroprotective and/or neuroregenerative agents |
EP1720886A1 (en) | 2004-03-02 | 2006-11-15 | Wyeth | Macrolides and methods for producing same |
WO2007061554A2 (en) * | 2005-10-21 | 2007-05-31 | Purdue Research Foundation | Dosage of 4-aminopyridine derivatives for treatment of central nervous system injuries |
CN104136413B (zh) * | 2011-12-27 | 2016-10-26 | 比皮艾思药物研发有限公司 | 用于预防或治疗癫痫症的苯基氨基甲酸酯化合物 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI874163A (fi) | 1986-09-26 | 1988-03-27 | Mitsui Toatsu Chemicals | Katekolderivat samt preparat innehaollande desamma foer haemmande och botande av regressiva sjukdomar i det centrala nervsystemet. |
US5214034A (en) | 1986-09-26 | 1993-05-25 | Mitsui Toatsu Chemicals, Incorporated | Catechol derivatives, and preventive and remedial preparations for regressive disorders in the central nervous system containing the same |
IT1206078B (it) | 1987-06-03 | 1989-04-14 | Polifarma Spa | Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico |
US5232923A (en) | 1988-03-18 | 1993-08-03 | Mitsui Toatsu Chemicals, Incorporated | Catechol derivatives and pharmaceutical preparations containing same |
US5166317A (en) | 1988-10-31 | 1992-11-24 | Houston Biotechnology Incorporated | Neurotrophic factor |
US5215969A (en) | 1989-08-11 | 1993-06-01 | Hahnemann University | Dopaminergic neurotrophic factor for treatment of Parkinson's disease |
US5620971A (en) | 1991-05-09 | 1997-04-15 | Vertex Pharmaceuticals Incorporated | Biologically active acylated amino acid derivatives |
US5744485A (en) | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
IL115685A (en) * | 1994-11-16 | 2000-08-31 | Vertex Pharma | Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
US6037370A (en) | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
US5717092A (en) | 1996-03-29 | 1998-02-10 | Vertex Pharmaceuticals Inc. | Compounds with improved multi-drug resistance activity |
US5811434A (en) | 1996-11-13 | 1998-09-22 | Vertex Pharmacueticals Incorporated | Methods and compositions for stimulating neurite growth |
US5840736A (en) | 1996-11-13 | 1998-11-24 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
US5780484A (en) | 1996-11-13 | 1998-07-14 | Vertex Pharmaceuticals Incorporated | Methods for stimulating neurite growth with piperidine compounds |
US5935989A (en) * | 1996-12-31 | 1999-08-10 | Gpi Nil Holdings Inc. | N-linked ureas and carbamates of heterocyclic thioesters |
ZA98825B (en) * | 1997-02-27 | 1998-10-19 | Guilford Pharm Inc | Method of using neurotrophic carbamates and ureas |
-
1998
- 1998-08-25 US US09/139,672 patent/US6242468B1/en not_active Expired - Fee Related
-
1999
- 1999-08-24 BR BR9912988-4A patent/BR9912988A/pt not_active IP Right Cessation
- 1999-08-24 CA CA002341530A patent/CA2341530A1/en not_active Abandoned
- 1999-08-24 KR KR1020017002444A patent/KR20010072992A/ko not_active Application Discontinuation
- 1999-08-24 MX MXPA01001937A patent/MXPA01001937A/es not_active IP Right Cessation
- 1999-08-24 EP EP99943869A patent/EP1107757A2/en not_active Withdrawn
- 1999-08-24 CN CN99810011A patent/CN1313767A/zh active Pending
- 1999-08-24 WO PCT/US1999/019261 patent/WO2000010553A2/en not_active Application Discontinuation
- 1999-08-24 PL PL99346759A patent/PL346759A1/xx unknown
- 1999-08-24 JP JP2000565875A patent/JP2002523367A/ja active Pending
- 1999-08-24 CZ CZ2001274A patent/CZ2001274A3/cs unknown
- 1999-08-24 AU AU56879/99A patent/AU5687999A/en not_active Abandoned
- 1999-08-24 SK SK256-2001A patent/SK2562001A3/sk unknown
- 1999-08-24 IL IL14095899A patent/IL140958A0/xx unknown
- 1999-08-24 HU HU0103166A patent/HUP0103166A3/hu unknown
- 1999-08-24 EA EA200100271A patent/EA200100271A1/ru unknown
-
2001
- 2001-02-23 NO NO20010946A patent/NO20010946L/no not_active Application Discontinuation
- 2001-03-14 BG BG105340A patent/BG105340A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP1107757A2 (en) | 2001-06-20 |
HUP0103166A3 (en) | 2002-10-28 |
NO20010946D0 (no) | 2001-02-23 |
EA200100271A1 (ru) | 2001-10-22 |
CZ2001274A3 (cs) | 2001-09-12 |
JP2002523367A (ja) | 2002-07-30 |
IL140958A0 (en) | 2002-02-10 |
MXPA01001937A (es) | 2002-04-24 |
AU5687999A (en) | 2000-03-14 |
SK2562001A3 (en) | 2001-09-11 |
PL346759A1 (en) | 2002-02-25 |
WO2000010553A2 (en) | 2000-03-02 |
NO20010946L (no) | 2001-02-23 |
US6242468B1 (en) | 2001-06-05 |
CN1313767A (zh) | 2001-09-19 |
BG105340A (en) | 2001-12-29 |
HUP0103166A2 (hu) | 2002-05-29 |
CA2341530A1 (en) | 2000-03-02 |
KR20010072992A (ko) | 2001-07-31 |
WO2000010553A3 (en) | 2000-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0110079A (pt) | Combinação de compostos orgânicos | |
BR9912988A (pt) | Composição farmacêutica e método de desenvolvimento de atividade neuronial em animal | |
IL142824A (en) | Lipoic acid derivatives and their use as anti metabolic agents | |
BR0113136A (pt) | sistema computadorizado e método para projetar, planejar, modificar ou manter uma ou mais redes de comunicação | |
BR9714739A (pt) | Composição farmacêutica para reduzir a depressão respiratória e os efeitos colaterais inerentes de compostos opióides mu | |
BR0210568A (pt) | Conjugado, uso de um conjugado, composição farmacêutica, e, método para tratar câncer em um mamìfero | |
BR0110521A (pt) | Carbamatos azabicìclicos e seu uso como agonistas de receptores de alfa-7 acetilcolina nicotìnico | |
BR0207775A (pt) | Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização | |
NO981944L (no) | Lipopolyaminer som transfeksjonsmidler samt farmas÷ytisk anvendelse derav | |
BR9712834A (pt) | Esteres e amidas heterocìclicos | |
BRPI0515012A (pt) | substáncia quìmica, composição e formulação farmacêutica, método de tratamento, método de inibição de pelo menos uma enzima que utiliza atp e uso | |
TR200102029T2 (tr) | 1-Heterosiklil ikameli diarilaminler. | |
ATE305468T1 (de) | Chinuclidincarbamat derivate und deren verwendung als m3 antagonisten | |
NO20042964L (no) | Spiroazasykliske forbindelser som monoaminreseptormodulatorer | |
YU83600A (sh) | Adenozin a3 receptorski modulatori | |
BR0112631A (pt) | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, pacote, métodos de reduzir a condutáncia de cálcio de um receptor de capsaicina e de tratar um mamìfero e uso de um composto | |
DE60231868D1 (de) | Folat-mimetika und deren folatrezeptorbindende konjugate | |
BR9909077A (pt) | Uso de um antagonista para a osm ou um receptor de osm, composição farmacêutica, e, ensaio para a identificação de um antagonista da osm | |
PT1042301E (pt) | Novos derivados de acilguanidina como inibidores da absorcao ossea e como antagonistas do receptor da vitronectina | |
BR9814040A (pt) | Agudo no pulmão com fibrose com antagonistas de avb6 | |
BR0316305A (pt) | Composto ou um sal farmaceuticamente aceitável do mesmo, métodos para tratar a dor em um animal, para estimular a função do receptor opióide em uma célula, para preparar uma composição, e para tratar diarréia em um animal, composição, e kit | |
ATE231872T1 (de) | Thiazolopyrimidinderivate | |
BR9713338A (pt) | Benzonaftiridinas como terapêuticos brÈnquicos. | |
BRPI0518580A2 (pt) | mÉtodo para melhorar a depuraÇço hepÁtica de substÂncias xenobiàticas em um animal, kit adequado para alimentar Ácido lipàico a um animal, meio para comunicar informaÇço, composiÇço, e, uso da composiÇço que compreende Ácido lipàico | |
BR0317229A (pt) | Composição e uso de agonista completo de alfa7nachr |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4O, 5O, 6O, 7O E 8O ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007. |