BR9912437A - ácidos nucléicos codificando um receptor ligado à proteìna g envolvido na transdução sensória - Google Patents

ácidos nucléicos codificando um receptor ligado à proteìna g envolvido na transdução sensória

Info

Publication number
BR9912437A
BR9912437A BR9912437-8A BR9912437A BR9912437A BR 9912437 A BR9912437 A BR 9912437A BR 9912437 A BR9912437 A BR 9912437A BR 9912437 A BR9912437 A BR 9912437A
Authority
BR
Brazil
Prior art keywords
nucleic acids
acids encoding
protein involved
receptor linked
sensory transduction
Prior art date
Application number
BR9912437-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Charles S Zuker
Jon Elliott Adler
Juergen Lindemeier
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BR9912437A publication Critical patent/BR9912437A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR9912437-8A 1998-07-28 1999-07-27 ácidos nucléicos codificando um receptor ligado à proteìna g envolvido na transdução sensória BR9912437A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9546498P 1998-07-28 1998-07-28
US11274798P 1998-12-17 1998-12-17
PCT/US1999/017104 WO2000006593A1 (en) 1998-07-28 1999-07-27 Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction

Publications (1)

Publication Number Publication Date
BR9912437A true BR9912437A (pt) 2001-09-25

Family

ID=26790259

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9912437-8A BR9912437A (pt) 1998-07-28 1999-07-27 ácidos nucléicos codificando um receptor ligado à proteìna g envolvido na transdução sensória

Country Status (15)

Country Link
US (8) US6383778B1 (enExample)
EP (1) EP1100811B1 (enExample)
JP (2) JP4657450B2 (enExample)
KR (1) KR100643622B1 (enExample)
CN (1) CN1178952C (enExample)
AT (2) ATE474852T1 (enExample)
AU (2) AU764180B2 (enExample)
BR (1) BR9912437A (enExample)
CA (1) CA2335376C (enExample)
DE (2) DE69942622D1 (enExample)
DK (1) DK1100811T3 (enExample)
ES (1) ES2289817T3 (enExample)
IL (3) IL140980A0 (enExample)
NO (1) NO20010320L (enExample)
WO (1) WO2000006593A1 (enExample)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110075507A1 (en) * 1997-10-24 2011-03-31 Revalesio Corporation Diffuser/emulsifier
US7654728B2 (en) * 1997-10-24 2010-02-02 Revalesio Corporation System and method for therapeutic application of dissolved oxygen
US6702949B2 (en) 1997-10-24 2004-03-09 Microdiffusion, Inc. Diffuser/emulsifier for aquaculture applications
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
AU764180B2 (en) 1998-07-28 2003-08-14 Regents Of The University Of California, The Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
US6875574B1 (en) * 1999-01-27 2005-04-05 The Regents Of The University Of California Assays for sensory modulators using a sensory cell specific G-protein alpha subunit
GB9923146D0 (en) * 1999-09-30 1999-12-01 Imperial College Detector array
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
EP1263787B1 (en) * 2000-03-14 2005-09-28 Tularik, Inc. G-protein coupled receptor
AU2001251258B2 (en) 2000-04-07 2008-06-05 Senomyx, Inc. T2r taste receptors and genes encoding same
US7678539B2 (en) * 2000-08-10 2010-03-16 Corning Incorporated Arrays of biological membranes and methods and use thereof
US6977155B2 (en) * 2000-08-10 2005-12-20 Corning Incorporated Arrays of biological membranes and methods and use thereof
DK1612222T3 (da) * 2000-09-22 2010-11-01 Chemcom Sa Olfaktoriske og feromon G-proteinkoblede receptorer
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US6955887B2 (en) * 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
US7309577B2 (en) * 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
WO2002086079A2 (en) * 2001-04-20 2002-10-31 Mount Sinai School Of Medicine T1r3 a novel taste receptor
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
EP2327985B2 (en) 2001-06-26 2019-08-21 Senomyx, Inc. T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
JP5001512B2 (ja) * 2001-06-26 2012-08-15 セノミックス インコーポレイテッド Ｔ１ｒヘテロオリゴマー味覚受容体及び前記受容体を発現する細胞系並びに味覚化合物の特定のためのその使用
AU2002320294B2 (en) 2001-07-03 2009-01-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Mammalian sweet and amino acid heterodimeric taste receptors
AU2002329196B2 (en) 2001-07-06 2008-08-07 Senomyx, Inc. Human olfactory nucleotide-gated ion channels
EP1502112A4 (en) 2001-07-10 2008-07-23 Senomyx Inc USE OF SPECIFIC T2R TASTE RECIPES TO IDENTIFY CONNECTIONS WHICH BLOCK A BITTER TASTE
US20040175712A1 (en) * 2001-07-19 2004-09-09 Hagen Frederick S Method for the identification of activators of g protein-coupled receptors and nucleic acids encoding those receptors
EP1523308A4 (en) * 2001-07-20 2007-01-10 Us Gov Health & Human Serv PHENYL THIOCARBAMIDE (PTC) TREATMENT RECEPTOR
WO2003025137A2 (en) * 2001-09-18 2003-03-27 Irm, Llc Sweet taste receptors
WO2004027384A2 (en) * 2002-09-17 2004-04-01 Perkinelmer Life Sciences, Inc. Real-time detection of nucleic acid reactions
WO2005007891A2 (en) * 2003-06-19 2005-01-27 The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes
AU2004256023B2 (en) 2003-06-27 2008-03-13 Monell Chemical Senses Center Taste receptors of the T1R family from domestic cat
US7517968B2 (en) * 2003-07-07 2009-04-14 Syracuse University Rapid and inexpensive method for the purification of proteorhodopsin
NZ619746A (en) 2003-08-06 2014-05-30 Senomyx Inc Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
US20050106571A1 (en) 2003-10-02 2005-05-19 The Regents Of The University Of California Mammalian T1R3 sweet taste receptors
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
MY158077A (en) * 2005-02-04 2016-08-30 Senomyx Inc Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers tastants and taste enhancers for comestible compositions
TW200638882A (en) * 2005-02-04 2006-11-16 Senomyx Inc Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
US8796441B2 (en) * 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
AR055329A1 (es) * 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
AU2006304797B2 (en) 2005-10-20 2013-01-31 Senomyx, Inc. Chimeric human sweet-umami and umami-sweet taste receptors
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
EP2047254B1 (en) * 2006-04-20 2015-10-28 Givaudan SA Method relating to sweetness enhancement
US8148536B2 (en) 2006-04-21 2012-04-03 Senomyx, Inc. Comestible compositions comprising high potency savory flavorants, and processes for producing them
US9019300B2 (en) * 2006-08-04 2015-04-28 Apple Inc. Framework for graphics animation and compositing operations
US7777877B2 (en) * 2006-10-20 2010-08-17 California Institute Of Technology High efficiency coupling optics for pumping and detection of fluorescence
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
WO2008115290A2 (en) * 2006-10-25 2008-09-25 Revalesio Corporation Methods of wound care and treatment
JP5595041B2 (ja) 2006-10-25 2014-09-24 リバルシオ コーポレイション 酸素富化溶液を用いる、眼および他のヒト組織の治療処置の方法
US8784898B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of wound care and treatment
US8784897B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of therapeutic treatment of eyes
JP5306214B2 (ja) 2006-10-25 2013-10-02 リバルシオ コーポレイション 混合装置
US8609148B2 (en) * 2006-10-25 2013-12-17 Revalesio Corporation Methods of therapeutic treatment of eyes
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
WO2009025793A2 (en) 2007-08-21 2009-02-26 Senomyx, Inc. Human t2r bitterness receptors and uses thereof
US20100009008A1 (en) * 2007-10-25 2010-01-14 Revalesio Corporation Bacteriostatic or bacteriocidal compositions and methods
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
US20100303918A1 (en) * 2007-10-25 2010-12-02 Revalesio Corporation Compositions and methods for treating asthma and other lung disorders
US10125359B2 (en) * 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation
US20090227018A1 (en) * 2007-10-25 2009-09-10 Revalesio Corporation Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction
US20100029764A1 (en) * 2007-10-25 2010-02-04 Revalesio Corporation Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction
AU2008316794B2 (en) * 2007-10-25 2015-04-23 Revalesio Corporation Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction
US20100015235A1 (en) * 2008-04-28 2010-01-21 Revalesio Corporation Compositions and methods for treating multiple sclerosis
US20100303917A1 (en) * 2007-10-25 2010-12-02 Revalesio Corporation Compositions and methods for treating cystic fibrosis
US9745567B2 (en) * 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
CN102076327B (zh) * 2008-05-01 2014-04-16 利发利希奥公司 治疗消化功能紊乱的组合物和方法
CA2741336A1 (en) * 2008-10-22 2010-04-29 Revalesio Corporation Compositions and methods for treating thymic stromal lymphopoietin (tslp)-mediated conditions
US20100098659A1 (en) * 2008-10-22 2010-04-22 Revalesio Corporation Compositions and methods for treating matrix metalloproteinase 9 (mmp9)-mediated conditions
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
CN101763735B (zh) * 2010-02-01 2015-02-25 王茜 可具有负系统损失时间的动态信号控制系统的控制方法
CA2794483C (en) 2010-03-26 2020-07-07 Trustees Of Dartmouth College Vista regulatory t cell mediator protein, vista binding agents and use thereof
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
SG10201503600XA (en) 2010-05-07 2015-06-29 Revalesio Corp Compositions and methods for enhancing physiological performance and recovery time
EP3327035A1 (en) 2010-06-22 2018-05-30 Precision Biologics Inc. Colon and pancreas cancer specific antigens and antibodies
BR112013003110A2 (pt) 2010-08-12 2016-06-28 Revalesio Corp composições e métodos para tratamento de taupatia
WO2012040617A2 (en) 2010-09-23 2012-03-29 Neogenix Oncology, Inc. Colon and pancreas cancer peptidomimetics
US9067997B2 (en) 2011-05-25 2015-06-30 Innate Pharma Sa Anti-KIR antibodies for the treatment of inflammatory and autoimmune disorders
WO2013022948A1 (en) 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
TWI677507B (zh) 2012-06-22 2019-11-21 達特茅斯學院基金會 新穎之ｖｉｓｔａ－ｉｇ構築體及ｖｉｓｔａ－ｉｇ用於治療自體免疫、過敏及發炎病症之用途
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
EP2892558B1 (en) 2012-09-07 2019-04-10 The Trustees Of Dartmouth College Vista modulators for diagnosis and treatment of cancer
WO2014106176A1 (en) 2012-12-28 2014-07-03 Precision Biologics, Inc. Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
EP3080161B1 (en) 2013-12-09 2021-03-24 New York University Compositions and methods for phagocyte delivery of anti-staphylococcal agents
CN119775416A (zh) 2013-12-24 2025-04-08 杨森制药公司 抗vista抗体及片段
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
JP6755640B2 (ja) 2014-03-28 2020-09-16 味の素株式会社 甘味受容体キメラタンパク質及びその利用
JP6997619B2 (ja) 2014-06-11 2022-01-17 キャシー・エイ・グリーン 液性免疫の抑制または増進のための、ｖｉｓｔａアゴニスト及びｖｉｓｔａアンタゴニストの使用
AU2015357463B2 (en) 2014-12-05 2021-10-07 Immunext, Inc. Identification of VSIG8 as the putative vista receptor and its use thereof to produce vista/VSIG8 modulators
EP3722314A1 (en) 2015-06-24 2020-10-14 Janssen Pharmaceutica NV Anti-vista antibodies and fragments
MX2018009800A (es) 2016-02-12 2018-11-09 Janssen Pharmaceutica Nv Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos.
EP3448412A4 (en) 2016-04-15 2020-03-25 Immunext Inc. ANTI-HUMAN-VISTA ANTIBODIES AND USE THEREOF
WO2019006246A1 (en) * 2017-06-30 2019-01-03 The Rockefeller University N-ACYL AMIDES DERIVED FROM THE HUMAN MICROBIOTE FOR THE TREATMENT OF A HUMAN DISEASE
WO2021150686A1 (en) 2020-01-22 2021-07-29 Firmenich Incorporated High-sensitivity detection of gpcr activity and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146501A (en) 1975-12-12 1979-03-27 Henkin Robert I Process for isolating and purifying taste bud receptors for screening and evaluating tastants
US5688662A (en) * 1992-04-09 1997-11-18 Linguagen Corporation Gustducin polynucleotides, vectors, host cells and recombinant methods
AU764180B2 (en) * 1998-07-28 2003-08-14 Regents Of The University Of California, The Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
US20010037364A1 (en) 2000-05-10 2001-11-01 Michalek Nancy R. Management of enterprise communications
AU2002320294B2 (en) 2001-07-03 2009-01-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Mammalian sweet and amino acid heterodimeric taste receptors

Also Published As

Publication number Publication date
IL140980A (en) 2007-10-31
US20080249293A1 (en) 2008-10-09
KR20010085307A (ko) 2001-09-07
JP4657450B2 (ja) 2011-03-23
US20190018001A1 (en) 2019-01-17
JP2002521050A (ja) 2002-07-16
US10031129B2 (en) 2018-07-24
US20110105741A1 (en) 2011-05-05
US8568990B2 (en) 2013-10-29
US7863433B2 (en) 2011-01-04
AU2003254732A1 (en) 2003-11-20
CA2335376C (en) 2013-07-02
US6383778B1 (en) 2002-05-07
DE69936453T2 (de) 2008-03-06
EP1100811B1 (en) 2007-07-04
DE69942622D1 (de) 2010-09-02
US20140065643A1 (en) 2014-03-06
DE69936453D1 (de) 2007-08-16
DK1100811T3 (da) 2007-11-05
US7270967B2 (en) 2007-09-18
ATE474852T1 (de) 2010-08-15
CA2335376A1 (en) 2000-02-10
US20120142029A1 (en) 2012-06-07
IL184795A0 (en) 2007-12-03
US8071743B2 (en) 2011-12-06
NO20010320D0 (no) 2001-01-19
CN1178952C (zh) 2004-12-08
EP1100811A1 (en) 2001-05-23
AU5324199A (en) 2000-02-21
US7282557B2 (en) 2007-10-16
EP1100811A4 (en) 2002-07-31
HK1101639A1 (en) 2007-10-18
ES2289817T3 (es) 2008-02-01
CN1318068A (zh) 2001-10-17
AU764180B2 (en) 2003-08-14
US20020119526A1 (en) 2002-08-29
IL140980A0 (en) 2002-02-10
US20030022288A1 (en) 2003-01-30
KR100643622B1 (ko) 2006-11-10
JP2009201525A (ja) 2009-09-10
WO2000006593A1 (en) 2000-02-10
NO20010320L (no) 2001-03-28
JP5371567B2 (ja) 2013-12-18
ATE366256T1 (de) 2007-07-15

Similar Documents

Publication Publication Date Title
BR9912437A (pt) ácidos nucléicos codificando um receptor ligado à proteìna g envolvido na transdução sensória
BR9912545A (pt) ácidos nucleicos codificando um receptorcopulado a proteìna g envolvido em transduçãosensorial
WO2001018050A3 (en) T2r taste receptor family
WO2003004992A3 (en) Mammalian sweet and amino acid heterodimeric taste receptors
NO961115L (no) Humane metabotrope glutamatreseptorsubtyper (HMR4, HMR6, HMR7) og relaterte DNA forbindelser
WO2002044426A3 (en) Nod2 nucleic acids and proteins
BR9912455A (pt) ácidos nucléicos codificadores de proteìnas envolvidas em transdução sensória
ATE370233T1 (de) Zwei menschliche g-protein-gekoppelte rezeptorproteine: ebv-induzierter gpcr2 (ebi-2) und egd-1-ähnlicher gpcr
NO995458D0 (no) Humane 12-lignende reseptorproteiner, beslektede reagenser og metoder
GEP20094629B (en) Nogo receptor binding protein
WO2005033125A3 (en) Mammalian t1r3 sweet taste receptors
DE69636437D1 (de) Ligand polypeptide für hypophyse g-protein gekoppeltes rezeptor-protein, deren herstellung und anwendung
DE602005019495D1 (de) Ligand für den Formylpeptidrezeptorähnlichen- 2 (FPRL2) G Protein gekoppelten Rezeptor und dessen Anwendung
WO2002042458A3 (en) G protein coupled receptors
WO2002000719A3 (en) Human and mouse g-protein couipled receptors
WO2000045179A3 (en) Screening for modulators of g-protein subunit beta 3
ATE462721T1 (de) Breit einsetzbares verfahren zur identifizierung von modulatoren von g-protein gekoppelten rezeptoren
NO20011511L (no) Nukleinsyrer som koder for en G-protein gammasubenhet som er involvert i sensorisk transduksjon
DE69813476D1 (de) G-protein-gekoppelter rezeptor mit selektiver affinität für atp
DK1693456T3 (da) Fremgangsmåde til identificering af modulatorer af en G-protein-koblet receptor
WO2003052078A3 (en) Insect g protein-coupled receptor genes and uses thereof
DK1317564T3 (da) Screeningsfremgangsmåder til at identificere G-proteiner og andre forbindelser, som modulerer phosphodiesterase (PDE)-aktiviteten
EP1806362A3 (en) Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
DK1263787T3 (da) G-proteinkoblet receptor
DE69926624D1 (de) Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 (IX), 15, 18 (III), 24 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.