BR9910814A - Vacina para imunização terapêutica ou profilática contra vìrus da venezuelan equine encephalitis (vee), composição farmacêutica, processo para produção de uma resposta imune protetora contra vìrus vee em um mamìfero, e, vacina multivalente - Google Patents

Vacina para imunização terapêutica ou profilática contra vìrus da venezuelan equine encephalitis (vee), composição farmacêutica, processo para produção de uma resposta imune protetora contra vìrus vee em um mamìfero, e, vacina multivalente

Info

Publication number
BR9910814A
BR9910814A BR9910814-3A BR9910814A BR9910814A BR 9910814 A BR9910814 A BR 9910814A BR 9910814 A BR9910814 A BR 9910814A BR 9910814 A BR9910814 A BR 9910814A
Authority
BR
Brazil
Prior art keywords
vaccine
vee
virus
therapeutic
equine encephalitis
Prior art date
Application number
BR9910814-3A
Other languages
English (en)
Inventor
Alice Marie Bennett
Original Assignee
Secr Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secr Defence filed Critical Secr Defence
Publication of BR9910814A publication Critical patent/BR9910814A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"VACINA PARA IMUNIZAçãO TERAPêUTICA OU PROFILáTICA CONTRA VìRUS DA VENEZUELAN EQUINE ENCEPHALITIS (VEE), COMPOSIçãO FARMACêUTICA, PROCESSO PARA PRODUçãO DE UMA RESPOSTA IMUNE PROTETORA CONTRA VìRUS VEE EM UM MAMìFERO, E, VACINA MULTIVALENTE". Uma vacina terapêutica ou profilática para uso na proteção de mamíferos tais como humanos ou animais contra vírus da Venezuelan Equine Encephalitis (VEE) é descrita. Em particular, a vacina compreende um vírus recombinante tal como um vírus da vacínia recombinante que é capaz de expressar os genes estruturais de VEE na forma atenuada, que tem sido modificado para aumentar o efeito protetor da vacina. Isto é conseguido pela modificação da seq³ência de uma cepa de VEE atenuada e/ou colocando esta sob o controle de promotor modificado que aumenta a expressão do vetor. Formulações de vacina bem como processos de tratamento usando a vacina também são descritos.
BR9910814-3A 1998-05-29 1999-05-05 Vacina para imunização terapêutica ou profilática contra vìrus da venezuelan equine encephalitis (vee), composição farmacêutica, processo para produção de uma resposta imune protetora contra vìrus vee em um mamìfero, e, vacina multivalente BR9910814A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9811433A GB2337755B (en) 1998-05-29 1998-05-29 Virus vaccine
PCT/GB1999/001387 WO1999063098A1 (en) 1998-05-29 1999-05-05 Recombinant venezuelan equine encephalitis virus vaccine

Publications (1)

Publication Number Publication Date
BR9910814A true BR9910814A (pt) 2001-02-13

Family

ID=10832820

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9910814-3A BR9910814A (pt) 1998-05-29 1999-05-05 Vacina para imunização terapêutica ou profilática contra vìrus da venezuelan equine encephalitis (vee), composição farmacêutica, processo para produção de uma resposta imune protetora contra vìrus vee em um mamìfero, e, vacina multivalente

Country Status (14)

Country Link
US (2) USRE41745E1 (pt)
EP (1) EP1084261B8 (pt)
AR (1) AR020080A1 (pt)
AT (1) ATE275631T1 (pt)
AU (1) AU3834999A (pt)
BR (1) BR9910814A (pt)
CA (1) CA2329133C (pt)
DE (1) DE69920011T2 (pt)
DK (1) DK1084261T3 (pt)
ES (1) ES2224655T3 (pt)
GB (1) GB2337755B (pt)
MX (1) MXPA00011708A (pt)
PT (1) PT1084261E (pt)
WO (1) WO1999063098A1 (pt)

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GB2337755B (en) 1998-05-29 2003-10-29 Secr Defence Virus vaccine
US8623379B2 (en) 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
US20020106798A1 (en) 2000-03-02 2002-08-08 Robinson Harriet L. DNA expression vectors and methods of use
ES2334335T3 (es) * 2001-03-08 2010-03-09 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Mva que expresa genes de envoltura, gag y pol de vih modificados.
DE602004000851T2 (de) * 2003-10-30 2007-05-16 Avago Technologies General Ip (Singapore) Pte. Ltd. Akustisch gekoppelter Dünnschicht-Transformator mit zwei piezoelektrischen Elementen, welche entgegengesetzte C-Axen Orientierung besitzten
WO2008101349A1 (en) * 2007-02-23 2008-08-28 Her Majesty The Queen, In Right Of Canada, As Repesented By The Minister Of National Defence Recombinant viral vectors for prevention and protection against alphavirus infection
BRPI1012951A2 (pt) * 2009-06-09 2016-07-26 Defyrus Inc "administração de interferon para profilaxia ou tratamento de infecção por patôgeno"
BR112013020875A2 (pt) 2011-02-15 2019-09-24 Immune Design Corp método para indução de uma resposta imune específica para um imunógeno em um indivíduo.
JP6054942B2 (ja) 2011-04-08 2016-12-27 イミューン デザイン コーポレイション 免疫原性組成物、ならびに体液性および細胞性免疫応答を誘発するための該組成物の使用方法
US9555090B2 (en) 2012-04-04 2017-01-31 The United States of America as repesented by the Secretary of Army, on behalf of the U.S. Army Medical Research Institute of Infections Diseases Equine encephalitis virus vaccines and methods of using thereof
CN107540730B (zh) 2012-05-16 2021-07-16 免疫设计公司 用于hsv-2的疫苗
RU2673156C2 (ru) * 2012-11-05 2018-11-22 Ридженерон Фармасьютикалз, Инк. Генетически модифицированные не относящиеся к человеческому роду животные и способы их применения
EA035259B1 (ru) 2014-02-14 2020-05-21 Иммьюн Дизайн Корп. Иммунотерапия рака с применением комбинации местной и системной иммунной стимуляции
JP2017522312A (ja) 2014-07-15 2017-08-10 イミューン デザイン コーポレイション Ｔｌｒ４アゴニストアジュバント及びレンチウイルスベクターを用いたプライム・ブーストレジメン
EP3407910B1 (en) 2016-01-29 2022-04-13 Bavarian Nordic A/S Recombinant modified vaccinia virus ankara (mva) equine encephalitis virus vaccine
AU2017250358B2 (en) 2016-04-15 2023-06-01 Alpine Immune Sciences, Inc. ICOS ligand variant immunomodulatory proteins and uses thereof
US11078282B2 (en) 2016-04-15 2021-08-03 Alpine Immune Sciences, Inc. CD80 variant immunomodulatory proteins and uses thereof
US11471488B2 (en) 2016-07-28 2022-10-18 Alpine Immune Sciences, Inc. CD155 variant immunomodulatory proteins and uses thereof
US11834490B2 (en) 2016-07-28 2023-12-05 Alpine Immune Sciences, Inc. CD112 variant immunomodulatory proteins and uses thereof
CA3032120A1 (en) 2016-07-28 2018-02-01 Alpine Immune Sciences, Inc. Cd155 variant immunomodulatory proteins and uses thereof
EP3596116B1 (en) 2017-03-16 2023-09-06 Alpine Immune Sciences, Inc. Pd-l1 variant immunomodulatory proteins and uses thereof
CA3054068A1 (en) 2017-03-16 2018-09-20 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
JP2020511144A (ja) 2017-03-16 2020-04-16 アルパイン イミューン サイエンシズ インコーポレイテッド Ｐｄ−ｌ２バリアント免疫調節タンパク質及びその使用
MX2019011599A (es) 2017-03-30 2019-12-19 Univ Queensland Moleculas quimericas y usos de las mismas.
US12076369B2 (en) 2017-09-01 2024-09-03 The Frances Crick Institute Limited Immunoregulatory molecules and uses therefor
KR20230020022A (ko) 2017-10-10 2023-02-09 알파인 이뮨 사이언시즈, 인코포레이티드 Ctla-4 변이체 면역조절 단백질 및 이의 용도
TW201925223A (zh) 2017-10-18 2019-07-01 美商艾爾潘免疫科學有限公司 變異型icos 配位體免疫調節蛋白及相關組合物及方法
WO2019136179A1 (en) 2018-01-03 2019-07-11 Alpine Immune Sciences, Inc. Multi-domain immunomodulatory proteins and methods of use thereof
WO2019241758A1 (en) 2018-06-15 2019-12-19 Alpine Immune Sciences, Inc. Pd-1 variant immunomodulatory proteins and uses thereof
AU2019345151A1 (en) 2018-09-19 2021-04-29 Alpine Immune Sciences, Inc. Methods and uses of variant CD80 fusion proteins and related constructs
CA3120868A1 (en) 2018-11-30 2020-06-04 Alpine Immune Sciences, Inc. Cd86 variant immunomodulatory proteins and uses thereof
SG11202111033VA (en) 2019-04-17 2021-11-29 Alpine Immune Sciences Inc Methods and uses of variant icos ligand (icosl) fusion proteins
TW202208414A (zh) 2020-05-08 2022-03-01 美商艾爾潘免疫科學有限公司 April及baff抑制性免疫調節蛋白及其使用方法
CA3216795A1 (en) 2021-05-07 2022-11-10 Alpine Immune Sciences, Inc. Methods of dosing and treatment with a taci-fc fusion immunomodulatory protein
WO2023172883A1 (en) 2022-03-07 2023-09-14 Alpine Immune Sciences, Inc. Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses
WO2024077018A2 (en) 2022-10-04 2024-04-11 Alpine Immune Sciences, Inc. Methods and uses of taci-fc fusion immunomodulatory protein

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US5185440A (en) * 1989-06-20 1993-02-09 North Carolina State University cDNA clone coding for Venezuelan equine encephalitis virus and attenuating mutations thereof
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Also Published As

Publication number Publication date
DE69920011T2 (de) 2005-09-15
EP1084261A1 (en) 2001-03-21
EP1084261B8 (en) 2004-12-15
GB2337755B (en) 2003-10-29
CA2329133C (en) 2011-07-12
USRE41745E1 (en) 2010-09-21
US6936257B1 (en) 2005-08-30
ES2224655T3 (es) 2005-03-01
GB2337755A (en) 1999-12-01
GB9811433D0 (en) 1998-07-22
PT1084261E (pt) 2005-01-31
WO1999063098A1 (en) 1999-12-09
MXPA00011708A (es) 2005-10-13
DK1084261T3 (da) 2005-01-17
EP1084261B1 (en) 2004-09-08
DE69920011D1 (de) 2004-10-14
AU3834999A (en) 1999-12-20
ATE275631T1 (de) 2004-09-15
AR020080A1 (es) 2002-04-10
CA2329133A1 (en) 1999-12-09

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
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