BR112021026439A2 - Vacina para febre suína africana - Google Patents

Vacina para febre suína africana

Info

Publication number
BR112021026439A2
BR112021026439A2 BR112021026439A BR112021026439A BR112021026439A2 BR 112021026439 A2 BR112021026439 A2 BR 112021026439A2 BR 112021026439 A BR112021026439 A BR 112021026439A BR 112021026439 A BR112021026439 A BR 112021026439A BR 112021026439 A2 BR112021026439 A2 BR 112021026439A2
Authority
BR
Brazil
Prior art keywords
compositions
peptides
swine fever
african swine
animal
Prior art date
Application number
BR112021026439A
Other languages
English (en)
Inventor
Anat Zvi
Avi Zrachya
Avner Finger
Ofer Cohen
Original Assignee
Life Science Res Israel Ltd
Phibro Animal Health Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Science Res Israel Ltd, Phibro Animal Health Corporation filed Critical Life Science Res Israel Ltd
Publication of BR112021026439A2 publication Critical patent/BR112021026439A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/12011—Asfarviridae
    • C12N2710/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/12011—Asfarviridae
    • C12N2710/12034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

vacina para febre suína africana. peptídeos preditos serem imunogênicos contra o vírus da febre suína africana (asfv) e as composições de vacina que incluem os peptídeos são aqui descritos. em algumas modalidades, essas composições compreendem ou consistem em um ou mais peptídeos que compreendem a sequência de aminoácidos descrita nas seq id nos: 2 a 2273. em outras modalidades, as composições compreen-dem vetores virais ou células hospedeiras, ou combinações dos mes-mos, que compreendem um ou mais peptídeos. em outras modalida-des, as composições compreendem moléculas de ácido nucleico que compreendem um ou mais peptídeos. as composições descritas po-dem incluir um ou mais componentes adicionais, tais como, mas não se limitando a, um veículo, um adjuvante, um agente terapêutico adici-onal ou combinações dos mesmos. recipientes e kits que compreen-dem as composições são descritos. os usos das composições podem incluir a administração a um animal para induzir uma resposta imune no animal ou para imunizar o animal contra asfv. a administração pode ser realizada usando um ou mais dos vários métodos aqui descri-tos, tais como administração intramuscular ou intranasal.
BR112021026439A 2019-06-28 2020-06-26 Vacina para febre suína africana BR112021026439A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962868483P 2019-06-28 2019-06-28
US201962941381P 2019-11-27 2019-11-27
PCT/US2020/039846 WO2020264312A1 (en) 2019-06-28 2020-06-26 African swine fever vaccine

Publications (1)

Publication Number Publication Date
BR112021026439A2 true BR112021026439A2 (pt) 2022-02-15

Family

ID=71728905

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021026439A BR112021026439A2 (pt) 2019-06-28 2020-06-26 Vacina para febre suína africana

Country Status (10)

Country Link
US (1) US20220105170A1 (pt)
EP (1) EP3990012A1 (pt)
JP (1) JP2022538673A (pt)
KR (1) KR20220031028A (pt)
CN (1) CN113454102A (pt)
AU (1) AU2020304652A1 (pt)
BR (1) BR112021026439A2 (pt)
CA (1) CA3145228A1 (pt)
MX (1) MX2021015465A (pt)
WO (1) WO2020264312A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113845572B (zh) * 2020-08-26 2023-11-21 中国农业科学院兰州兽医研究所 一类促进猪机体产生广谱获得性免疫应答的多肽及其应用
CN114621321B (zh) * 2020-08-26 2024-04-05 中国农业科学院兰州兽医研究所 一类促进猪机体产生广谱性免疫应答的多肽及其应用
CN114044806B (zh) * 2020-08-26 2023-10-24 中国农业科学院兰州兽医研究所 一类促进猪机体产生广谱性免疫应答的多肽及其应用
CN112724203A (zh) * 2020-12-30 2021-04-30 郑州大学 一种非洲猪瘟病毒p54蛋白抗原表位肽及其应用
CN113061588B (zh) * 2021-05-20 2023-08-01 军事科学院军事医学研究院军事兽医研究所 缺失i226r基因的非洲猪瘟病毒减毒株及其活疫苗
CN113755505B (zh) * 2021-09-30 2023-05-02 绵阳市游仙区创新科技产业技术研究院 治疗和/或预防非洲猪瘟病毒的疫苗及其制备方法
WO2024031045A2 (en) * 2022-08-04 2024-02-08 Malcolm Thomas Dominant negative antigen approach for prophylactic and post-infection treatment of swine against african swine fever virus
US11969453B2 (en) 2023-06-14 2024-04-30 Nae Woi Korea., Ltd. Horseradish and cinnamon mixed extract composition for suppression of avian viral epidemic diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1897958B (zh) 2003-12-24 2011-02-02 特拉维夫大学拉玛特有限公司 从天然肉桂提取物中获得的抗病毒制剂
US8008268B2 (en) * 2006-07-25 2011-08-30 Merial Limited Vaccines against vesicular stomatitis
EP2771349B1 (en) * 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
ES2401276B1 (es) * 2011-10-04 2014-02-19 Fundació Centre De Recerca En Sanitat Animal Utilización de una construcción genica y/o peptídica para la fabricación de una vacuna para la prevención y/o tratamiento de la infección causada por el virus de la peste porcina africana (vppa).
CN103805615A (zh) * 2014-02-19 2014-05-21 孙洁 密码子优化的非洲猪瘟病毒p54基因、其核酸疫苗及应用
US10279031B2 (en) 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using

Also Published As

Publication number Publication date
KR20220031028A (ko) 2022-03-11
CN113454102A (zh) 2021-09-28
US20220105170A1 (en) 2022-04-07
WO2020264312A1 (en) 2020-12-30
CA3145228A1 (en) 2020-12-30
MX2021015465A (es) 2022-03-11
AU2020304652A1 (en) 2022-02-24
JP2022538673A (ja) 2022-09-05
EP3990012A1 (en) 2022-05-04

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