BR9909900A - Aproximação combinatória paralela à descoberta e otimização de catalisadores e usos disso - Google Patents

Aproximação combinatória paralela à descoberta e otimização de catalisadores e usos disso

Info

Publication number
BR9909900A
BR9909900A BR9909900-4A BR9909900A BR9909900A BR 9909900 A BR9909900 A BR 9909900A BR 9909900 A BR9909900 A BR 9909900A BR 9909900 A BR9909900 A BR 9909900A
Authority
BR
Brazil
Prior art keywords
discovery
optimization
catalysts
combinatorial approach
approach parallel
Prior art date
Application number
BR9909900-4A
Other languages
English (en)
Inventor
Eric N Jacobsen
Matthew S Sigman
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of BR9909900A publication Critical patent/BR9909900A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/14Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00Catalysts, in general, characterised by their form or physical properties
    • B01J35/19Catalysts containing parts with different compositions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/00745Inorganic compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/00745Inorganic compounds
    • B01J2219/00747Catalysts
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/08Methods of screening libraries by measuring catalytic activity
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/18Libraries containing only inorganic compounds or inorganic materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Patente de Invenção: <B>"APROXIMAçãO COMBINATóRIA PARALELA à DESCOBERTA E OTIMIZAçãO DE CATALISADORES E USOS DISSO"<D>. A presente invenção fornece métodos e composições, isto é, bibliotecas sintéticas de compostos candidatos, úteis na descoberta e otimização de compostos os quais catalisam pelo menos uma transformação química. Em certos exemplos, os compostos sujeitos catalisam uma transformação quimioseletiva, regioseletiva, estereoseletiva ou enantioseletiva.
BR9909900-4A 1998-04-02 1999-04-02 Aproximação combinatória paralela à descoberta e otimização de catalisadores e usos disso BR9909900A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8046198P 1998-04-02 1998-04-02
US09/064,462 US6316616B1 (en) 1998-04-02 1998-04-22 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
PCT/US1999/007265 WO1999051546A1 (en) 1998-04-02 1999-04-02 Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof

Publications (1)

Publication Number Publication Date
BR9909900A true BR9909900A (pt) 2001-01-09

Family

ID=26744545

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909900-4A BR9909900A (pt) 1998-04-02 1999-04-02 Aproximação combinatória paralela à descoberta e otimização de catalisadores e usos disso

Country Status (11)

Country Link
US (3) US6316616B1 (pt)
EP (1) EP1066228A1 (pt)
JP (1) JP2002510554A (pt)
CN (1) CN1305443A (pt)
AU (1) AU760340B2 (pt)
BR (1) BR9909900A (pt)
CA (1) CA2326387A1 (pt)
CZ (1) CZ20003543A3 (pt)
HU (1) HUP0102442A3 (pt)
NZ (1) NZ507186A (pt)
WO (1) WO1999051546A1 (pt)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316616B1 (en) * 1998-04-02 2001-11-13 President And Fellows Of Harvard College Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
US6521561B1 (en) 1998-05-01 2003-02-18 President And Fellows Of Harvard College Main-group metal based asymmetric catalysts and applications thereof
FR2798659B1 (fr) * 1999-09-17 2001-11-16 Bp Chemicals Snc Procede et appareillage pour le developpement de catalyseurs de polymerisation
AU1476501A (en) * 1999-11-09 2001-06-06 Sri International Screening and analysis of polymers, specialty chemicals and catalysts using radiography
AU1591301A (en) 1999-11-09 2001-06-06 Sri International Workstation, apparatus, and methods for the high-throughput synthesis, screeningand characterization of combinatorial libraries
EP1235765A2 (en) * 1999-12-06 2002-09-04 Glaxo Group Limited Systems and methods to facilitate multiple order combinatorial chemical processes
US6770754B2 (en) * 2000-11-29 2004-08-03 Glen Research Coporation Universal supports for oligonucleotide synthesis
US20020102735A1 (en) * 2000-12-06 2002-08-01 General Electric Company Use of gradient mixtures for screening and optimization of catalysts for the production of condensation polymers
WO2002102820A1 (en) 2001-06-20 2002-12-27 Nuevolution A/S Nucleoside derivatives for library preparation
DE10208252A1 (de) * 2002-02-26 2003-09-04 Celanese Ventures Gmbh Konvalent fixierte Non-Metallocene, Verfahren zur Herstellung von diesen und deren Verwendung zur Polymerisation von Olefinen
DE10209177A1 (de) * 2002-03-01 2003-09-18 Studiengesellschaft Kohle Mbh Ein Hoch-Durchsatz-Screening-Verfahren zur Bestimmung der Enantioselektivität von Katalysatoren, Biokatalysatoren und Agenzien
US7504364B2 (en) * 2002-03-01 2009-03-17 Receptors Llc Methods of making arrays and artificial receptors
EP1487978B1 (en) 2002-03-15 2008-11-19 Nuevolution A/S An improved method for synthesising templated molecules
EP1539980B1 (en) * 2002-08-01 2016-02-17 Nuevolution A/S Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules
EP1534421B1 (en) * 2002-08-15 2006-09-27 Velocys, Inc. Tethered catalyst processes in microchannel reactors and systems containing a tethered catalyst or tethered chiral auxiliary
US20050136483A1 (en) * 2003-09-03 2005-06-23 Receptors Llc Nanodevices employing combinatorial artificial receptors
US20060057625A1 (en) * 2002-09-16 2006-03-16 Carlson Robert E Scaffold-based artificial receptors and methods
US20050170385A1 (en) * 2002-09-16 2005-08-04 Receptors Llc Artificial receptors including gradients
WO2005003326A2 (en) * 2003-03-28 2005-01-13 Receptors Llc. Artificial receptors including reversibly immobilized building blocks and methods
US7469076B2 (en) * 2003-09-03 2008-12-23 Receptors Llc Sensors employing combinatorial artificial receptors
US20040137481A1 (en) * 2002-09-16 2004-07-15 Receptors Llc Artificial receptor building blocks, components, and kits
US20050037381A1 (en) * 2002-09-16 2005-02-17 Receptors Llc Artificial receptors, building blocks, and methods
US20050037429A1 (en) * 2003-03-28 2005-02-17 Receptors Llc Artificial receptors including reversibly immobilized building blocks and methods
US20050037428A1 (en) * 2002-09-16 2005-02-17 Receptors Llc Artificial receptors including reversibly immobilized building blocks, the building blocks, and methods
AU2003273792B2 (en) 2002-10-30 2011-07-07 Nuevolution A/S Method for the synthesis of a bifunctional complex
EP2175019A3 (en) 2002-12-19 2011-04-06 Nuevolution A/S Quasirandom structure and function guided synthesis methods
WO2004074429A2 (en) 2003-02-21 2004-09-02 Nuevolution A/S Method for producing second-generation library
DE602004023960D1 (de) 2003-09-18 2009-12-17 Nuevolution As Methode zur Gewinnung struktureller Informationen kodierter Moleküle und zur Selektion von Verbindungen
JP4614968B2 (ja) * 2003-12-23 2011-01-19 ビーエーエスエフ ソシエタス・ヨーロピア 昆虫、蛛形類および線虫を駆除するための1−(アゾリン−2−イル)アミノ−1,2−ジフェニルエタン化合物
FR2865821B1 (fr) * 2004-01-30 2006-07-21 Novalyst Discovery Procede utile pour caracteriser la reactivite catalytique de catalyseur(s)
WO2005103983A2 (en) * 2004-04-01 2005-11-03 Manyworlds, Inc. Generative investment process
WO2006028930A2 (en) * 2004-09-03 2006-03-16 Receptors Llc Combinatorial artificial receptors including tether building blocks on scaffolds
US7985715B2 (en) * 2004-09-11 2011-07-26 Receptors Llc Combinatorial artificial receptors including peptide building blocks
US20060287937A1 (en) * 2005-01-18 2006-12-21 Manyworlds, Inc. Generative Investment Process
ITMI20050062A1 (it) 2005-01-20 2006-07-21 Polimeri Europa Spa Processo per la preparazione di fenolo
US20060258875A1 (en) * 2005-05-10 2006-11-16 Clementine Reyes Methods for manufacturing supported nanocatalysts and methods for using supported nanocatalysts
WO2007062664A2 (en) 2005-12-01 2007-06-07 Nuevolution A/S Enzymatic encoding methods for efficient synthesis of large libraries
US20080059395A1 (en) * 2006-01-10 2008-03-06 Manyworlds, Inc. Adaptive Online Experimentation
US8097229B2 (en) 2006-01-17 2012-01-17 Headwaters Technology Innovation, Llc Methods for manufacturing functionalized inorganic oxides and polymers incorporating same
US7632774B2 (en) * 2006-03-30 2009-12-15 Headwaters Technology Innovation, Llc Method for manufacturing supported nanocatalysts having an acid-functionalized support
DE102006028451A1 (de) * 2006-06-21 2008-01-10 Studiengesellschaft Kohle Mbh Verfahren zur Herstellung von N-Acyl-α-Aminonitrilen
EP3540059A1 (en) 2010-04-16 2019-09-18 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes
US20130274144A1 (en) * 2011-08-29 2013-10-17 The Board Of Trustees Of The University Of Illiois Compounds, reactions, and screening methods
CN103012325B (zh) * 2011-09-22 2015-05-13 中国石油化工股份有限公司 丙烯环氧化反应生产环氧丙烷的方法
CN103012485B (zh) * 2011-09-22 2015-10-21 中国石油化工股份有限公司 乙酰丙酮缩苯甲酰肼钼络合物及其制备方法
CN103012324B (zh) * 2011-09-22 2014-09-10 中国石油化工股份有限公司 丙烯环氧化反应的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007329A1 (en) 1989-01-06 1990-07-12 The Regents Of The University Of California Selection method for pharmacologically active compounds
US5599538A (en) 1989-04-25 1997-02-04 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US5637459A (en) 1990-06-11 1997-06-10 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chimeric selex
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5593853A (en) 1994-02-09 1997-01-14 Martek Corporation Generation and screening of synthetic drug libraries
US5525735A (en) 1994-06-22 1996-06-11 Affymax Technologies Nv Methods for synthesizing diverse collections of pyrrolidine compounds
US5582997A (en) 1994-08-24 1996-12-10 Torrey Pines Institute For Molecular Studies Lysine/leucine polypeptides, mixture sets and libraries thereof
JPH11514012A (ja) 1996-07-23 1999-11-30 サイミックス・テクノロジーズ 有機金属化合物及び触媒の組み合わせ合成並びに分析
US6316616B1 (en) * 1998-04-02 2001-11-13 President And Fellows Of Harvard College Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof

Also Published As

Publication number Publication date
CN1305443A (zh) 2001-07-25
WO1999051546A1 (en) 1999-10-14
CZ20003543A3 (cs) 2001-09-12
US20020102612A1 (en) 2002-08-01
NZ507186A (en) 2003-11-28
CA2326387A1 (en) 1999-10-14
US6709824B2 (en) 2004-03-23
EP1066228A1 (en) 2001-01-10
JP2002510554A (ja) 2002-04-09
AU3379099A (en) 1999-10-25
HUP0102442A2 (hu) 2001-10-28
HUP0102442A3 (en) 2002-06-28
US6316616B1 (en) 2001-11-13
AU760340B2 (en) 2003-05-15
WO1999051546A9 (en) 1999-11-18
US20040235023A1 (en) 2004-11-25

Similar Documents

Publication Publication Date Title
BR9909900A (pt) Aproximação combinatória paralela à descoberta e otimização de catalisadores e usos disso
BR9709350A (pt) Membro de ligação especìfico, comp[osição farmacêutica, ácido nuclieco, célula hospedeira, uso de um membro de ligação especìfico e processo para sua produção
PT653439E (pt) Oligonucleotidos e sua aplicacao
BR9910174A (pt) Processo para se obter um gene recombinante otimizado de resistência à praga, biblioteca, e, processo para se obter um organismo que seja patogênico a uma praga de vegetal
ATE373672T1 (de) Synthese von methoxynukleoside und enzymatische nukleisäure moleküle
BR9908343A (pt) Processo para a sìntese de alimentação industrial quìmica e combustìvel de alta octanagem e composição de combustìvel de alta octanagem
BR9813968A (pt) Moléculas de ácido nucléico que codificam proteìnas tendo atividade frutosil transferase e processos para produzir inulina de cadeia longa
ES2171184T3 (es) Sistemas cataliticos de polimerizacion, su produccion y uso.
ES2095827T3 (es) Procedimiento para la purificacion de poliesteres resorbibles.
DE69611442D1 (de) Enzymatische synthese von glykosidischen verbindungen
ES2167870T3 (es) Sistemas cataliticos de polimerizacion que comprenden ligandos ciclopentadienuro heterociclicos fusionados.
BR9907249A (pt) Conector de válvula de borboleta
HU9902655D0 (en) Pharmaceutical composition of hedgehog proteins and use thereof
BR9711365A (pt) Arranjo de po-o submarino para produ-Æo de Äleo ou g s fora-da-costa
BR0204774A (pt) Processo para reformação a vapor autotérmica catalìtica, de álcoois
BR9915790A (pt) Material de revestimento de construções, processo para a sua preparação e a sua aplicação
ES2131972T3 (es) Derivados de sulfamato de derivados del 1,3,5(10)-estratrieno, procedimiento para su fabricacion y composiciones farmaceuticas que contienen estos compuestos.
MX9304769A (es) Subfamilia ptp-d de fosfatasas de la proteina tirosina.
BR9910120A (pt) Compostos de espisulosina tendo atividade antitumor
BR9804309A (pt) Tensoativos
BR9714049A (pt) Imidazopiridazinas
BR0100164A (pt) Modelos de farmacóforo, métodos de rastreio e identificação da potência inibidora de citocromo p-450 de antagonistas do receptor neuroquinina-1
DE69534470D1 (de) Lgmd- gen kodierend für einer calcium abhängigen protease
ES2138275T3 (es) Procedimiento para la obtencion de bis(4-hidroxiaril)-alcanos.
DE69004620D1 (de) Alkaliphosphate als Korrosionsschutzmittel für Reibbeläge oder als feste Schmiermittel dafür.

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A,9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1990 DE 25/02/2009.