BR9908083A - polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusão - Google Patents
polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusãoInfo
- Publication number
- BR9908083A BR9908083A BRPI9908083-4A BR9908083A BR9908083A BR 9908083 A BR9908083 A BR 9908083A BR 9908083 A BR9908083 A BR 9908083A BR 9908083 A BR9908083 A BR 9908083A
- Authority
- BR
- Brazil
- Prior art keywords
- tuberculosis
- polypeptide
- host cell
- expression vector
- dna molecule
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1289—Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2475398A | 1998-02-18 | 1998-02-18 | |
| US09/072,596 US6458366B1 (en) | 1995-09-01 | 1998-05-05 | Compounds and methods for diagnosis of tuberculosis |
| PCT/US1999/003265 WO1999042118A2 (en) | 1998-02-18 | 1999-02-17 | Compounds and methods for diagnosis of tuberculosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9908083A true BR9908083A (pt) | 2007-07-17 |
Family
ID=26698832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9908083-4A BR9908083A (pt) | 1998-02-18 | 1999-02-17 | polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusão |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US6458366B1 (https=) |
| EP (1) | EP1091749A1 (https=) |
| JP (1) | JP2002530050A (https=) |
| CN (1) | CN1312723A (https=) |
| AU (1) | AU2681999A (https=) |
| BR (1) | BR9908083A (https=) |
| CA (1) | CA2322617A1 (https=) |
| WO (1) | WO1999042118A2 (https=) |
Families Citing this family (50)
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|---|---|---|---|---|
| US6592877B1 (en) | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| DK1144447T3 (da) * | 1998-11-04 | 2010-02-08 | Isis Innovation | Dianostisk tuberkulosetest |
| US6196917B1 (en) * | 1998-11-20 | 2001-03-06 | Philips Electronics North America Corp. | Goal directed user interface |
| US7083796B2 (en) * | 2000-06-20 | 2006-08-01 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| US8143386B2 (en) * | 1999-04-07 | 2012-03-27 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
| EP1229931A4 (en) | 1999-10-07 | 2003-05-28 | Corixa Corp | FUSION PROTEINS FROM MYCOBACTERIUM TUBERCULOSIS |
| AU779846B2 (en) * | 1999-10-07 | 2005-02-17 | Corixa Corporation | Methods of using a mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of heterologous proteins |
| US7009042B1 (en) | 1999-10-07 | 2006-03-07 | Corixa Corporation | Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins |
| US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
| AU2001241738A1 (en) * | 2000-02-25 | 2001-09-03 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
| US7026465B2 (en) * | 2002-02-15 | 2006-04-11 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis |
| RU2277540C2 (ru) * | 2003-07-29 | 2006-06-10 | Зао "Велес Фарма" | Способ диагностики туберкулезной инфекции, рекомбинантная плазмидная днк, кодирующая синтез гибридного белка cfp10-esat6 из mycobacterium tuberculosis, способ его получения, гибридный белок cfp10-esat6 и его применение |
| US8475735B2 (en) * | 2004-11-01 | 2013-07-02 | Uma Mahesh Babu | Disposable immunodiagnostic test system |
| CN102220357B (zh) * | 2004-11-16 | 2013-12-25 | 克鲁塞尔荷兰公司 | 包含重组病毒载体的多价疫苗 |
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| PL2068918T5 (pl) | 2006-09-26 | 2024-12-02 | Access To Advanced Health Institute | Kompozycja szczepionki zawierająca syntetyczny adiuwant |
| US9297803B2 (en) | 2006-11-01 | 2016-03-29 | Immport Therapeutics, Inc. | Compositions and methods for immunodominant antigens |
| EP2226635B1 (en) * | 2007-12-28 | 2013-03-13 | BL Co., Ltd | Immunodetection assay for mycobacterium tuberculosis complex |
| EP2284262A4 (en) * | 2008-05-28 | 2012-02-22 | Wako Pure Chem Ind Ltd | PRIMER AND PROBE FOR DETECTION OF MYCOBACTERIUM INTRACELLULARE, AND METHOD FOR DETECTION OF MYCOBACTERIUM INTRACELLULARE USING THE PRIMER OR PROBE |
| AU2009273132B2 (en) | 2008-07-25 | 2015-09-03 | Glaxo Group Limited | The tuberculosis Rv2386c protein, compositions and uses thereof |
| CA2731549C (en) | 2008-07-25 | 2018-07-17 | Glaxo Group Limited | Compositions and methods for treating tuberculosis |
| US20100159485A1 (en) * | 2008-12-19 | 2010-06-24 | Centre For Dna Fingerprinting And Diagnostics | Detection of mycobacterium tuberculosis |
| WO2010089098A1 (de) | 2009-02-05 | 2010-08-12 | Deklatec Gmbh | Verfahren und mittel für die tuberkulose diagnostik |
| CA2764374C (en) | 2009-06-05 | 2019-11-19 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
| BR112012018669A2 (pt) | 2010-01-27 | 2017-09-05 | Glaxosmithkline Biologicals Sa | Proteína rv3616c modificada, uso de uma proteína rv3616c modificada, polinucleotídeo, uso de um polinucleotídeo, composição farmacêutica, composição imunogênica, proteína de fusão, e, polipeptídeo. |
| EP2694680A4 (en) * | 2011-04-01 | 2014-09-10 | Occam Biolabs Inc | METHOD AND KITS FOR DETECTION OF CELL-FREE NURVIVAL-SPECIFIC NUCLEIC ACIDS |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
| EP2573107A1 (en) * | 2011-09-21 | 2013-03-27 | Norwegian Institute of Public Health | A recombinant fusion protein |
| ES2729967T3 (es) | 2012-02-07 | 2019-11-07 | Infectious Disease Res Inst | Formulaciones de adyuvante mejoradas que comprenden agonistas de TLR4 y métodos para usar las mismas |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| MX370573B (es) | 2013-04-18 | 2019-12-17 | Immune Design Corp | Monoterapia con glucopiranosil lipido a para usarse en el tratamiento del cancer. |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| EP3382040A3 (en) | 2013-12-03 | 2018-10-31 | Kusuma School of Biological Sciences | Genetic markers for diagnosis of tuberculosis caused by mycobacterium tuberculosis |
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| KR20250008135A (ko) | 2016-06-01 | 2025-01-14 | 액세스 투 어드밴스드 헬스 인스티튜트 | 사이징제를 함유하는 나노명반 입자 |
| CN106011296B (zh) * | 2016-08-01 | 2019-10-25 | 武汉大学 | 一种结核分枝杆菌Rv1768基因微滴数字PCR绝对定量检测试剂盒 |
| CN110073215B (zh) * | 2016-09-22 | 2024-04-30 | 佩斯诊断公司 | 结核分枝杆菌蛋白诊断测定和结核病检测和诊断装置 |
| CA3141577A1 (en) | 2019-05-25 | 2020-12-03 | Infectious Disease Research Institute | Composition and method for spray drying an adjuvant vaccine emulsion |
| CN113388623A (zh) * | 2020-03-11 | 2021-09-14 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv新基因Rv2203c及其编码蛋白和应用 |
| CN113004362B (zh) * | 2021-02-26 | 2023-08-15 | 南方科技大学 | 一种订书钉核酸、dna纳米机器人及其制备方法和应用 |
| CN114034860A (zh) * | 2021-11-01 | 2022-02-11 | 宁夏大学 | 一种结核分枝杆菌mtb39a蛋白抗体间接elisa检测方法及其试剂盒 |
| CN114989312B (zh) * | 2022-06-27 | 2023-07-21 | 安徽理工大学 | 一种结核分枝杆菌融合蛋白dr2及其应用 |
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- 1998-05-05 US US09/072,596 patent/US6458366B1/en not_active Expired - Fee Related
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1999
- 1999-02-17 BR BRPI9908083-4A patent/BR9908083A/pt not_active IP Right Cessation
- 1999-02-17 AU AU26819/99A patent/AU2681999A/en not_active Abandoned
- 1999-02-17 CN CN99809541A patent/CN1312723A/zh active Pending
- 1999-02-17 EP EP99907065A patent/EP1091749A1/en not_active Withdrawn
- 1999-02-17 JP JP2000532132A patent/JP2002530050A/ja not_active Withdrawn
- 1999-02-17 WO PCT/US1999/003265 patent/WO1999042118A2/en not_active Ceased
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| US6949246B2 (en) | 2005-09-27 |
| US20050181419A1 (en) | 2005-08-18 |
| US6458366B1 (en) | 2002-10-01 |
| AU2681999A (en) | 1999-09-06 |
| CA2322617A1 (en) | 1999-08-26 |
| CN1312723A (zh) | 2001-09-12 |
| US7906277B2 (en) | 2011-03-15 |
| EP1091749A1 (en) | 2001-04-18 |
| JP2002530050A (ja) | 2002-09-17 |
| US7122196B2 (en) | 2006-10-17 |
| US20070141087A1 (en) | 2007-06-21 |
| US20030135026A1 (en) | 2003-07-17 |
| WO1999042118A8 (en) | 1999-10-21 |
| WO1999042118A2 (en) | 1999-08-26 |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007. |