BR9907191A - Compostos azatricìclicos - Google Patents

Compostos azatricìclicos

Info

Publication number
BR9907191A
BR9907191A BR9907191-6A BR9907191A BR9907191A BR 9907191 A BR9907191 A BR 9907191A BR 9907191 A BR9907191 A BR 9907191A BR 9907191 A BR9907191 A BR 9907191A
Authority
BR
Brazil
Prior art keywords
hydrogen
substituent
sigma
azathricyl
compounds
Prior art date
Application number
BR9907191-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Peter Anthony Crooks
Niranjan Madhukar Deo
Original Assignee
Reynolds Tobacco Co R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reynolds Tobacco Co R filed Critical Reynolds Tobacco Co R
Publication of BR9907191A publication Critical patent/BR9907191A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR9907191-6A 1998-04-02 1999-02-26 Compostos azatricìclicos BR9907191A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/054,179 US5986100A (en) 1998-04-02 1998-04-02 Pharmaceutical compositions and methods for use
PCT/US1999/004324 WO1999051601A1 (en) 1998-04-02 1999-02-26 Azatricyclic compounds

Publications (1)

Publication Number Publication Date
BR9907191A true BR9907191A (pt) 2000-12-26

Family

ID=21989278

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907191-6A BR9907191A (pt) 1998-04-02 1999-02-26 Compostos azatricìclicos

Country Status (14)

Country Link
US (2) US5986100A (enExample)
EP (1) EP1066287B1 (enExample)
JP (1) JP2002510689A (enExample)
KR (1) KR100613050B1 (enExample)
AT (1) ATE248839T1 (enExample)
AU (1) AU2794899A (enExample)
BR (1) BR9907191A (enExample)
CA (1) CA2317570A1 (enExample)
DE (1) DE69910993T2 (enExample)
DK (1) DK1066287T3 (enExample)
ES (1) ES2205778T3 (enExample)
MX (1) MXPA00009624A (enExample)
PT (1) PT1066287E (enExample)
WO (1) WO1999051601A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200100096A (et) 1998-08-18 2002-06-17 Ucb, S.A. Asatsüklilise tüvistruktuuriga tsükliline ühend, seda sisaldav farmatseutiline kompositsioon ning selle kasutamine ravimina
HUP0501017A3 (en) * 2001-12-14 2010-06-28 Targacept Methods and compositions for treatment of central nervous system disorders
US20030162770A1 (en) 2002-02-22 2003-08-28 Davis Bonnie M. Use of modulators of nicotinic receptors for treatment of cognitive dysfunction
US7897766B2 (en) * 2005-09-23 2011-03-01 Abbott Laboratories Amino-aza-adamantane derivatives and methods of use
US8314119B2 (en) * 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
AU2012203831B2 (en) * 2006-11-06 2013-12-19 Abbvie Bahamas Ltd Azaadamantane derivatives and their uses as nicotinic acetylcholine receptors ligands
MX2009010176A (es) * 2007-03-23 2009-10-12 Abbott Lab Derivados de aza-adamantano 4-substituidos y metodos de uso de los mismos.
EP2069346B1 (en) * 2007-03-23 2011-12-21 Abbott Laboratories Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof
CN106074548A (zh) 2010-09-23 2016-11-09 艾伯维巴哈马有限公司 氮杂金刚烷衍生物的一水合物
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2022886A1 (en) * 1989-08-08 1991-02-09 Raymond Baker Substituted pyridines, their preparation, formulations and use in dementia
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
EP0492903A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma
WO1995003306A1 (en) * 1993-07-22 1995-02-02 E.I. Du Pont De Nemours And Company Arthropodicidal azacyclic heterocycles
US5510355A (en) * 1994-09-06 1996-04-23 Bencherif; Merouane Depolarizing skeletal muscle relaxants
AU5383196A (en) * 1995-05-17 1996-11-29 R.J. Reynolds Tobacco Company Pharmaceutical compositions for prevention and treatment of central nervous system disorders
US5583140A (en) * 1995-05-17 1996-12-10 Bencherif; Merouane Pharmaceutical compositions for the treatment of central nervous system disorders
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds

Also Published As

Publication number Publication date
ES2205778T3 (es) 2004-05-01
EP1066287A1 (en) 2001-01-10
MXPA00009624A (es) 2005-06-20
DE69910993T2 (de) 2004-07-22
DK1066287T3 (da) 2004-01-19
CA2317570A1 (en) 1999-10-14
PT1066287E (pt) 2004-01-30
JP2002510689A (ja) 2002-04-09
ATE248839T1 (de) 2003-09-15
US5986100A (en) 1999-11-16
DE69910993D1 (de) 2003-10-09
KR20010052172A (ko) 2001-06-25
KR100613050B1 (ko) 2006-08-25
EP1066287B1 (en) 2003-09-03
US6211372B1 (en) 2001-04-03
WO1999051601A1 (en) 1999-10-14
AU2794899A (en) 1999-10-25

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Legal Events

Date Code Title Description
PC Transfer

Free format text: TARGACEPT, INC. (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT. CL: CO7D 471/18; A61K 31/439.

Ipc: C07D 471/18 (2008.04)

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.