BR9816106A - Carboxilase de piruvato de corynebacterium glutamicum - Google Patents

Carboxilase de piruvato de corynebacterium glutamicum

Info

Publication number
BR9816106A
BR9816106A BR9816106-7A BR9816106A BR9816106A BR 9816106 A BR9816106 A BR 9816106A BR 9816106 A BR9816106 A BR 9816106A BR 9816106 A BR9816106 A BR 9816106A
Authority
BR
Brazil
Prior art keywords
corynebacterium glutamicum
pyruvate carboxylase
carboxylase
glutamicum pyruvate
piruvate
Prior art date
Application number
BR9816106-7A
Other languages
English (en)
Inventor
Anthony J Sinskey
Phillip A Lessard
Laura B Willis
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of BR9816106A publication Critical patent/BR9816106A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"CARBOXILASE DE PIRUVATO DE CORYNEBACTERIUM GLUTAMICUM" A presente invenção se refere a uma enzima anaplerótica de Corynebacterium glutamicum que reabastece o oxalo-acetato consumido durante a produção de lisina e ácido glutâmico em fermentações industriais. Especificamente, as moléculas de ácido nucléico isoladas são providas de acordo com a proteína de carboxilase de piruvato. Polipeptídeos de carboxilase de piruvato são também providos.
BR9816106-7A 1998-12-23 1998-12-23 Carboxilase de piruvato de corynebacterium glutamicum BR9816106A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/027301 WO2000039305A1 (en) 1998-12-23 1998-12-23 PYRUVATE CARBOXYLASE FROM $i(CORYNEBACTERIUM GLUTAMICUM)

Publications (1)

Publication Number Publication Date
BR9816106A true BR9816106A (pt) 2001-09-11

Family

ID=22268534

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9816106-7A BR9816106A (pt) 1998-12-23 1998-12-23 Carboxilase de piruvato de corynebacterium glutamicum

Country Status (9)

Country Link
EP (1) EP1147198A1 (pt)
JP (1) JP2003503006A (pt)
KR (1) KR20010112232A (pt)
CN (1) CN1336958A (pt)
AU (1) AU2203399A (pt)
BR (1) BR9816106A (pt)
CA (1) CA2356446A1 (pt)
MX (1) MXPA01006290A (pt)
WO (1) WO2000039305A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511250A (ja) 1998-04-13 2002-04-16 ザ ユニバーシティ オブ ジョージア リサーチファウンデーション，インコーポレイティド 微生物におけるオキサロ酢酸由来生化学物質の生産増強のためのピルビン酸カルボキシラーゼの過剰発現
EP1325135B1 (en) 2000-10-13 2004-12-29 Archer-Daniels-Midland Company Feedback-resistant pyruvate carboxylase gene from corynebacterium
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
BRPI0716980A2 (pt) * 2006-09-15 2013-10-22 Cj Cheiljedang Corp Corynebacteria com produtividade de l-lisina aumentada e método de produção da l-lisina usando a mesma
KR100830826B1 (ko) 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
US8932861B2 (en) 2008-04-10 2015-01-13 Cj Cheiljedang Corporation Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
BR122021015693B1 (pt) * 2011-12-21 2022-05-03 Cj Cheiljedang Corporation Microrganismo produtor de lisina e método para a produção de l-lisina
CN103695454A (zh) * 2013-12-18 2014-04-02 山东寿光巨能金玉米开发有限公司 表达l-赖氨酸转运蛋白的重组质粒、工程菌及应用
KR101922113B1 (ko) * 2017-04-25 2018-11-27 한양대학교 산학협력단 패오닥틸럼 트리코누튬 유래 피루브산 전달효소
CN113755492B (zh) * 2020-07-20 2023-05-30 中国科学院天津工业生物技术研究所 丙酮酸羧化酶基因启动子的突变体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ289051B6 (cs) * 1993-08-24 2001-10-17 Ajinomoto Co. Inc. Mutanta karboxylázy fosfoenolpyrohroznanu, kódový řetězec pro tuto mutantu, produkční mikroorganismus a způsob výroby aminokyseliny
ES2238773T3 (es) * 1997-10-04 2005-09-01 Degussa Ag Procedimiento para la produccion microbiana de aminoacidos de las familias del aspartato y/o glutamato, y agentes utilizables en el procedimiento.

Also Published As

Publication number Publication date
EP1147198A1 (en) 2001-10-24
CN1336958A (zh) 2002-02-20
MXPA01006290A (es) 2002-04-17
JP2003503006A (ja) 2003-01-28
KR20010112232A (ko) 2001-12-20
WO2000039305A1 (en) 2000-07-06
CA2356446A1 (en) 2000-07-06
AU2203399A (en) 2000-07-31

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Legal Events

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B08F Application fees: application dismissed [chapter 8.6 patent gazette]