BR9815501A - Derivados de prostaglandina isentos de efeitos colaterais para o tratamento de glaucoma - Google Patents
Derivados de prostaglandina isentos de efeitos colaterais para o tratamento de glaucomaInfo
- Publication number
- BR9815501A BR9815501A BR9815501-6A BR9815501A BR9815501A BR 9815501 A BR9815501 A BR 9815501A BR 9815501 A BR9815501 A BR 9815501A BR 9815501 A BR9815501 A BR 9815501A
- Authority
- BR
- Brazil
- Prior art keywords
- glaucoma
- treatment
- side effects
- prostaglandin derivatives
- derivatives free
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
<B>"DERIVADOS DE PROSTAGLANDINA ISENTOS DE EFEITOS COLATERAIS PARA O TRATAMENTO DE GLAUCOMA"<D>. A invenção descreve um novo método e composições para o tratamento de glaucoma e hipertensão ocular. O método se baseia no uso de agonistas prostanóides receptores de EP~ 1~, que efetivamente reduzem a pressão intraocular, mas, que não apresentam qualquer efeito ou apenas um efeito reduzido sobre a pigmentação da íris. O análogo de prostaglandina que é um agonista seletivo de EP~ 1~ é aplicado topicamente sobre o olho.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9702706A SE9702706D0 (sv) | 1997-07-11 | 1997-07-11 | Prostaglandin derivatives devoid of side-effects for the treatment of glaucoma |
PCT/SE1998/001368 WO1999002165A1 (en) | 1997-07-11 | 1998-07-10 | Prostaglandin derivatives devoid of side-effects for the treatment of glaucoma |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9815501A true BR9815501A (pt) | 2001-07-17 |
Family
ID=20407743
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9815501-6A BR9815501A (pt) | 1997-07-11 | 1998-07-10 | Derivados de prostaglandina isentos de efeitos colaterais para o tratamento de glaucoma |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1014991A1 (pt) |
JP (1) | JP2002509543A (pt) |
KR (1) | KR20010021682A (pt) |
CN (1) | CN1169528C (pt) |
AU (1) | AU739828B2 (pt) |
BR (1) | BR9815501A (pt) |
CA (1) | CA2294779A1 (pt) |
HK (1) | HK1029942A1 (pt) |
HU (1) | HUP0003106A3 (pt) |
IL (1) | IL133871A (pt) |
IS (1) | IS5333A (pt) |
NO (1) | NO20000062D0 (pt) |
NZ (1) | NZ501834A (pt) |
PL (1) | PL337940A1 (pt) |
RU (1) | RU2207858C2 (pt) |
SE (1) | SE9702706D0 (pt) |
SK (1) | SK183499A3 (pt) |
TR (1) | TR200000008T2 (pt) |
WO (1) | WO1999002165A1 (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9803761D0 (sv) * | 1998-11-04 | 1998-11-04 | Synphora Ab | Method to avoid increased iridial pigmentation during prostaglandin treatment |
AU766163B2 (en) | 1999-03-05 | 2003-10-09 | Duke University | C16 unsaturated fp-selective prostaglandins analogs |
US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
US6531504B2 (en) * | 2001-05-17 | 2003-03-11 | Allergan, Inc. | Prostanoic acid derivatives as agents for lowering intraocular pressure |
GB0112699D0 (en) | 2001-05-24 | 2001-07-18 | Resolution Chemicals Ltd | Process for the preparation of prostglandins and analogues thereof |
US6713268B2 (en) * | 2001-06-26 | 2004-03-30 | Allergan, Inc. | Methods of identifying ocular hypotensive compounds having reduced hyperpigmentation |
AU2003299137A1 (en) * | 2002-09-16 | 2004-04-23 | Texas Tech University System | Inhibition of metallo-beta-lactamase |
GB0501192D0 (en) | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
PL212658B1 (pl) * | 2005-04-18 | 2012-11-30 | Inst Farmaceutyczny | Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub> |
US8455513B2 (en) | 2007-01-10 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-aminoisoquinoline compounds |
EP2305304A4 (en) | 2008-04-28 | 2011-08-10 | Nat University Corp Hamamatsu University School Of Medicine | IMMUNOSTIMULATOR WITH EP1 AGONIST |
US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
ES2672624T3 (es) | 2009-05-01 | 2018-06-15 | Aerie Pharmaceuticals, Inc. | Inhibidores de mecanismo doble para el tratamiento de enfermedades |
WO2011046569A1 (en) * | 2009-10-16 | 2011-04-21 | Cayman Chemical Company | Process for the preparation of f-series prostaglandins |
DK2831077T3 (en) | 2012-03-28 | 2016-08-15 | Merck Patent Gmbh | BICYCLIC PYRAZINO DERIVATIVES |
JP2012246301A (ja) * | 2012-08-10 | 2012-12-13 | Cayman Chemical Co Inc | F系プロスタグランジン類を調製する方法 |
PL3811943T3 (pl) | 2013-03-15 | 2023-06-12 | Aerie Pharmaceuticals, Inc. | Związek do stosowania w leczeniu zaburzeń oczu |
US9643927B1 (en) | 2015-11-17 | 2017-05-09 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
JP6907319B2 (ja) | 2016-08-31 | 2021-07-21 | アエリエ ファーマシューティカルズ インコーポレイテッド | 眼科用組成物 |
CA3057872A1 (en) | 2017-03-31 | 2018-10-04 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
CA3112391A1 (en) | 2018-09-14 | 2020-03-19 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4132738A (en) * | 1978-02-23 | 1979-01-02 | Miles Laboratories, Inc. | Preparation of 15-deoxy-16-hydroxyprostaglandins |
ES2105333T3 (es) * | 1992-10-13 | 1997-10-16 | Alcon Lab Inc | Combinaciones de prostaglandinas y derivados de clonidina para el tratamiento del glaucoma. |
-
1997
- 1997-07-11 SE SE9702706A patent/SE9702706D0/xx unknown
-
1998
- 1998-07-10 CA CA002294779A patent/CA2294779A1/en not_active Abandoned
- 1998-07-10 EP EP98934082A patent/EP1014991A1/en not_active Ceased
- 1998-07-10 IL IL13387198A patent/IL133871A/en not_active IP Right Cessation
- 1998-07-10 WO PCT/SE1998/001368 patent/WO1999002165A1/en not_active Application Discontinuation
- 1998-07-10 HU HU0003106A patent/HUP0003106A3/hu unknown
- 1998-07-10 CN CNB988070456A patent/CN1169528C/zh not_active Ceased
- 1998-07-10 BR BR9815501-6A patent/BR9815501A/pt not_active IP Right Cessation
- 1998-07-10 JP JP50856099A patent/JP2002509543A/ja not_active Withdrawn
- 1998-07-10 RU RU2000103224/14A patent/RU2207858C2/ru not_active IP Right Cessation
- 1998-07-10 SK SK1834-99A patent/SK183499A3/sk unknown
- 1998-07-10 TR TR2000/00008T patent/TR200000008T2/xx unknown
- 1998-07-10 AU AU83683/98A patent/AU739828B2/en not_active Ceased
- 1998-07-10 PL PL98337940A patent/PL337940A1/xx unknown
- 1998-07-10 NZ NZ501834A patent/NZ501834A/en unknown
- 1998-07-10 KR KR1020007000240A patent/KR20010021682A/ko not_active Application Discontinuation
-
2000
- 2000-01-06 NO NO20000062A patent/NO20000062D0/no unknown
- 2000-01-07 IS IS5333A patent/IS5333A/is unknown
-
2001
- 2001-02-09 HK HK01100916A patent/HK1029942A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TR200000008T2 (tr) | 2000-05-22 |
AU739828B2 (en) | 2001-10-18 |
SE9702706D0 (sv) | 1997-07-11 |
NZ501834A (en) | 2002-05-31 |
NO20000062L (no) | 2000-01-06 |
KR20010021682A (ko) | 2001-03-15 |
AU8368398A (en) | 1999-02-08 |
RU2207858C2 (ru) | 2003-07-10 |
WO1999002165A1 (en) | 1999-01-21 |
HK1029942A1 (en) | 2001-04-20 |
HUP0003106A3 (en) | 2002-12-28 |
HUP0003106A2 (hu) | 2001-01-29 |
NO20000062D0 (no) | 2000-01-06 |
CN1262623A (zh) | 2000-08-09 |
SK183499A3 (en) | 2000-07-11 |
IS5333A (is) | 2000-01-07 |
IL133871A0 (en) | 2001-04-30 |
IL133871A (en) | 2004-09-27 |
CN1169528C (zh) | 2004-10-06 |
EP1014991A1 (en) | 2000-07-05 |
CA2294779A1 (en) | 1999-01-21 |
PL337940A1 (en) | 2000-09-11 |
JP2002509543A (ja) | 2002-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007. |