BR9811830A - Processo de cultivo que proporciona manutenção de células germinais primitivas de ave por perìodos prolongados, processo de produção de aves quiméricas, e, linhagem celular de pgc de ave - Google Patents
Processo de cultivo que proporciona manutenção de células germinais primitivas de ave por perìodos prolongados, processo de produção de aves quiméricas, e, linhagem celular de pgc de aveInfo
- Publication number
- BR9811830A BR9811830A BR9811830-7A BR9811830A BR9811830A BR 9811830 A BR9811830 A BR 9811830A BR 9811830 A BR9811830 A BR 9811830A BR 9811830 A BR9811830 A BR 9811830A
- Authority
- BR
- Brazil
- Prior art keywords
- bird
- cell line
- primitive
- chimeric
- germ cells
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000012423 maintenance Methods 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 title 1
- 210000004602 germ cell Anatomy 0.000 title 1
- 238000003822 preparative gas chromatography Methods 0.000 abstract 2
- 241000271566 Aves Species 0.000 abstract 1
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 abstract 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 abstract 1
- 241000287828 Gallus gallus Species 0.000 abstract 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 102100020880 Kit ligand Human genes 0.000 abstract 1
- 101710177504 Kit ligand Proteins 0.000 abstract 1
- 102100032352 Leukemia inhibitory factor Human genes 0.000 abstract 1
- 108090000581 Leukemia inhibitory factor Proteins 0.000 abstract 1
- 241000286209 Phasianidae Species 0.000 abstract 1
- 235000013330 chicken meat Nutrition 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0271—Chimeric animals, e.g. comprising exogenous cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/30—Bird
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/105—Insulin-like growth factors [IGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biodiversity & Conservation Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Catching Or Destruction (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
Abstract
"PROCESSO DE CULTIVO QUE PROPORCIONA MANUTENçãO DE CéLULAS GERMINAIS PRIMITIVAS DE AVE POR PERìODOS PROLONGADOS, PROCESSO DE PRODUçãO DE AVES QUIMéRICAS, E, LINHAGEM CELULAR DE PGC DE AVE". Um sistema de cultura para manutenção de PGCs de ave por longos períodos em cultura de tecido é proporcionado. Este sistema de cultura usa LIF, bFGF, IGF-I e SCF. As PGCs resultantes são úteis para a produção de aves quiméricas e transgênicas, em particular, de galinhas ou perus.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/905,773 US6156569A (en) | 1997-08-04 | 1997-08-04 | Prolonged culturing of avian primordial germ cells (PGCs) using specific growth factors, use thereof to produce chimeric avians |
US12762498A | 1998-08-03 | 1998-08-03 | |
PCT/US1998/015635 WO1999006533A1 (en) | 1997-08-04 | 1998-08-04 | Avian primordial germ cell (pgc) cell line and a method for long term culturing thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9811830A true BR9811830A (pt) | 2000-08-15 |
Family
ID=26825804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9811830-7A BR9811830A (pt) | 1997-08-04 | 1998-08-04 | Processo de cultivo que proporciona manutenção de células germinais primitivas de ave por perìodos prolongados, processo de produção de aves quiméricas, e, linhagem celular de pgc de ave |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040226058A1 (pt) |
EP (2) | EP1007633B1 (pt) |
JP (1) | JP2003532364A (pt) |
CN (1) | CN1195844C (pt) |
AT (1) | ATE307196T1 (pt) |
AU (1) | AU736087B2 (pt) |
BR (1) | BR9811830A (pt) |
CA (1) | CA2300380A1 (pt) |
DE (1) | DE69831958T2 (pt) |
ES (1) | ES2252851T3 (pt) |
NZ (1) | NZ502712A (pt) |
WO (1) | WO1999006533A1 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100378747B1 (ko) * | 1999-02-11 | 2003-04-07 | 한미약품공업 주식회사 | 조류의 다능성 배자생식세포주 및 이의 제조방법 |
US6333192B1 (en) | 1999-08-09 | 2001-12-25 | North Carolina State University | Method of producing an undifferentiated avian cell culture using avian primordial germ cells |
US6354242B1 (en) | 2000-03-23 | 2002-03-12 | North Carolina State University | Methods for gamete production in birds |
WO2003025159A1 (en) | 2001-08-13 | 2003-03-27 | Embrex, Inc. | Methods for injecting avian eggs |
FR2836924B1 (fr) * | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
KR100569168B1 (ko) * | 2003-08-08 | 2006-04-07 | (주)아비코아생명공학연구소 | 조류 정원줄기세포의 배양방법 및 이에 의해 수득한 조류정원줄기세포 |
US20060174362A1 (en) | 2005-02-01 | 2006-08-03 | Origen Therapeutics, Inc. | Long-term culture of avian primordial germ cells (PGCs) |
CN100366734C (zh) * | 2006-03-02 | 2008-02-06 | 扬州大学 | 一种鸡精原细胞分离纯化方法 |
RU2473688C2 (ru) | 2006-08-09 | 2013-01-27 | Вивалис | Способ получения трансгенных птиц с использованием эмбриональных стволовых клеток |
CN100443588C (zh) * | 2006-12-11 | 2008-12-17 | 中国农业科学院北京畜牧兽医研究所 | 静宁鸡胚成纤维细胞系及其培养方法 |
EP1985305A1 (en) | 2007-04-24 | 2008-10-29 | Vivalis | Duck embryonic derived stem cell lines for the production of viral vaccines |
WO2011019844A1 (en) | 2009-08-13 | 2011-02-17 | Crystal Bioscience Inc. | Transgenic animal for production of antibodies having minimal cdrs |
US8865462B2 (en) * | 2010-01-20 | 2014-10-21 | Crystal Bioscience Inc. | Sustained culture of avian gonocytes |
AU2013204327B2 (en) | 2012-04-20 | 2016-09-01 | Aviagen | Cell transfection method |
CN103674653B (zh) * | 2013-12-19 | 2016-08-24 | 浙江省农业科学院 | 一种原始生殖细胞的爬片方法 |
WO2016091272A1 (en) * | 2014-12-12 | 2016-06-16 | Central Veterinary Research Laboratory | System and method for establishing a long-term culture of avian primordial germ cells and uses thereof |
MX2021010611A (es) | 2019-03-05 | 2021-11-12 | The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo | Aves con genoma editado. |
CN111500531A (zh) * | 2020-05-15 | 2020-08-07 | 扬州大学 | 一种鸡PGCs在体外长期培养的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2726003B1 (fr) * | 1994-10-21 | 2002-10-18 | Agronomique Inst Nat Rech | Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires |
US6156569A (en) * | 1997-08-04 | 2000-12-05 | University Of Massachusetts Office Of Vice Chancellor For Research At Amherst | Prolonged culturing of avian primordial germ cells (PGCs) using specific growth factors, use thereof to produce chimeric avians |
US6140118A (en) * | 1999-08-11 | 2000-10-31 | Wisconsin Alumni Research Foundation | Avian blastodermal cell lines |
-
1998
- 1998-08-04 AU AU87593/98A patent/AU736087B2/en not_active Ceased
- 1998-08-04 ES ES98939101T patent/ES2252851T3/es not_active Expired - Lifetime
- 1998-08-04 CN CNB988098741A patent/CN1195844C/zh not_active Expired - Fee Related
- 1998-08-04 JP JP2000505275A patent/JP2003532364A/ja active Pending
- 1998-08-04 WO PCT/US1998/015635 patent/WO1999006533A1/en active IP Right Grant
- 1998-08-04 AT AT98939101T patent/ATE307196T1/de not_active IP Right Cessation
- 1998-08-04 CA CA002300380A patent/CA2300380A1/en not_active Abandoned
- 1998-08-04 DE DE69831958T patent/DE69831958T2/de not_active Expired - Fee Related
- 1998-08-04 NZ NZ502712A patent/NZ502712A/xx active IP Right Revival
- 1998-08-04 EP EP98939101A patent/EP1007633B1/en not_active Expired - Lifetime
- 1998-08-04 EP EP05022690A patent/EP1616943A1/en not_active Withdrawn
- 1998-08-04 BR BR9811830-7A patent/BR9811830A/pt not_active Application Discontinuation
-
2004
- 2004-06-18 US US10/870,805 patent/US20040226058A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20040226058A1 (en) | 2004-11-11 |
AU736087B2 (en) | 2001-07-26 |
CA2300380A1 (en) | 1999-02-11 |
ES2252851T3 (es) | 2006-05-16 |
EP1007633B1 (en) | 2005-10-19 |
CN1273600A (zh) | 2000-11-15 |
DE69831958D1 (de) | 2006-03-02 |
EP1007633A1 (en) | 2000-06-14 |
CN1195844C (zh) | 2005-04-06 |
DE69831958T2 (de) | 2006-07-27 |
EP1007633A4 (en) | 2002-06-05 |
NZ502712A (en) | 2003-01-31 |
JP2003532364A (ja) | 2003-11-05 |
AU8759398A (en) | 1999-02-22 |
WO1999006533A1 (en) | 1999-02-11 |
ATE307196T1 (de) | 2005-11-15 |
EP1616943A1 (en) | 2006-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: O DEPOSITANTE DEIXOU DE APRESENTAR MANIFESTACAO SOBRE O PARECER NEGATIVO DE FOLHAS 85 A 86 PUBLICADO NA RPI N.O 1982, DE 30/12/2008. ASSIM, DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |