BR9809120A - Uso de 5-(4-(2-(n-metil-n-(2-piridil)amino)-etóxi)benzil)2,4-tiazo lidinodiona no tratamento de sìndrome policìstica do ovário e diabetes decorrente de gestação - Google Patents
Uso de 5-(4-(2-(n-metil-n-(2-piridil)amino)-etóxi)benzil)2,4-tiazo lidinodiona no tratamento de sìndrome policìstica do ovário e diabetes decorrente de gestaçãoInfo
- Publication number
- BR9809120A BR9809120A BR9809120-4A BR9809120A BR9809120A BR 9809120 A BR9809120 A BR 9809120A BR 9809120 A BR9809120 A BR 9809120A BR 9809120 A BR9809120 A BR 9809120A
- Authority
- BR
- Brazil
- Prior art keywords
- pregnancy
- amino
- methyl
- treatment
- polycystic ovary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Patente de Invenção:<B>"USO DE 5-(4-(2-(N-METIL-N-(2-PIRIDIL)AMINO)-E-TóXI)BENZIL)2,4-TIAZO LIDINODIONA NO TRATAMENTO DE SìNDROME POLICìSTICA DO OVáRIO E DIABETES DECORRENTE DE GESTAçãO"<D>. Esta invenção apresenta novos métodos de uso de derivados de tiazolidinona e agentes anti-hiperglicêmicos afins para tratar populações em risco de desenvolver diabetes melito não-dependente de insulina (NIDDM) e complicações que se originam dele. Em uma modalidade, os compostos da invenção são usados para tratar síndrome policística do ovário a fim de prevenir ou retardar o início de diabetes melito não-dependente de insulina. Em outra modalidade, os compostos da invenção são usados para tratar diabetes decorrente de gestação a fim de prevenir ou retardar o início de diabetes melito-não-dependente de insulina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/856,987 US5874454A (en) | 1993-09-15 | 1997-05-15 | Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
PCT/US1998/010113 WO1998051305A1 (en) | 1997-05-15 | 1998-05-14 | Use of 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)-ethoxy)benzyl)2,4-thiazolidinedione in the treatment of polycystic ovary syndrome and gestational diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9809120A true BR9809120A (pt) | 2000-08-01 |
Family
ID=25324901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9809120-4A BR9809120A (pt) | 1997-05-15 | 1998-05-14 | Uso de 5-(4-(2-(n-metil-n-(2-piridil)amino)-etóxi)benzil)2,4-tiazo lidinodiona no tratamento de sìndrome policìstica do ovário e diabetes decorrente de gestação |
Country Status (14)
Country | Link |
---|---|
US (1) | US5874454A (pt) |
EP (1) | EP0981346A1 (pt) |
JP (1) | JP2001525827A (pt) |
KR (1) | KR20010012556A (pt) |
AU (1) | AU731690B2 (pt) |
BR (1) | BR9809120A (pt) |
CA (1) | CA2282473A1 (pt) |
HU (1) | HUP0003397A3 (pt) |
IL (1) | IL132125A0 (pt) |
IS (1) | IS5177A (pt) |
NO (1) | NO995549D0 (pt) |
PL (1) | PL336764A1 (pt) |
WO (1) | WO1998051305A1 (pt) |
ZA (1) | ZA984084B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6046222A (en) * | 1993-09-15 | 2000-04-04 | Warner-Lambert Company | Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
JP2001072592A (ja) | 1999-07-01 | 2001-03-21 | Kyowa Hakko Kogyo Co Ltd | テロメラーゼ阻害剤 |
GB0019223D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0021865D0 (en) * | 2000-09-06 | 2000-10-18 | Smithkline Beecham Plc | Novel pharmaceutical |
US6452014B1 (en) | 2000-12-22 | 2002-09-17 | Geron Corporation | Telomerase inhibitors and methods of their use |
EP2068909B1 (en) | 2007-03-30 | 2012-04-25 | Ambrx, Inc. | Modified fgf-21 polypeptides and their uses |
US9339458B2 (en) * | 2009-02-18 | 2016-05-17 | Itf Research Pharma, S.L.U. | Use of vaginal insulin sensitizing agents |
ES2344183B1 (es) * | 2009-02-18 | 2011-06-10 | Italfarmaco, S.A. | Uso de agentes sensibilizantes a insulina por via vaginal. |
LT3412302T (lt) | 2014-10-24 | 2021-07-26 | Bristol-Myers Squibb Company | Modifikuoti fgf-21 polipeptidai ir jų panaudojimai |
RU2665969C1 (ru) * | 2017-05-04 | 2018-09-05 | Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) | Способ лечения синдрома поликистозных яичников |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
US4873255A (en) * | 1987-02-04 | 1989-10-10 | Sankyo Company Limited | Thiazolidinone derivatives, their preparation and their use |
DE3856378T2 (de) * | 1987-09-04 | 2000-05-11 | Beecham Group Plc | Substituierte Thiazolidindionderivate |
US5223522A (en) * | 1988-03-08 | 1993-06-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
US5120754A (en) * | 1988-03-08 | 1992-06-09 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
US5061717A (en) * | 1988-03-08 | 1991-10-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
MX15171A (es) * | 1988-03-08 | 1993-05-01 | Pfizer | Derivados de tiazolidinodiona hipoglicemicos |
US4897405A (en) * | 1989-04-21 | 1990-01-30 | American Home Products Corporation | Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents |
GB8919434D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
GB8919417D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
JP3544659B2 (ja) * | 1990-02-09 | 2004-07-21 | ファルマシア・アンド・アップジョン・カンパニー | インスリン感性化剤類の高血圧治療のための使用 |
GB9023585D0 (en) * | 1990-10-30 | 1990-12-12 | Beecham Group Plc | Novel compounds |
GB9023583D0 (en) * | 1990-10-30 | 1990-12-12 | Beecham Group Plc | Novel compounds |
ES2092112T3 (es) * | 1991-06-25 | 1996-11-16 | Pfizer | Agentes hipoglicemicos de tiazolidindiona. |
US5457109A (en) * | 1993-09-15 | 1995-10-10 | Warner-Lambert Company | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
ATE376829T1 (de) * | 1993-09-15 | 2007-11-15 | Daiichi Sankyo Co Ltd | Verwendung von thiazolidindionen zur vorbeugung oder verzögerung des auftretens des nichtinsulinabhängigen diabetes mellitus (niddm) |
-
1997
- 1997-05-15 US US08/856,987 patent/US5874454A/en not_active Expired - Fee Related
-
1998
- 1998-05-14 JP JP54965498A patent/JP2001525827A/ja active Pending
- 1998-05-14 CA CA002282473A patent/CA2282473A1/en not_active Abandoned
- 1998-05-14 HU HU0003397A patent/HUP0003397A3/hu unknown
- 1998-05-14 EP EP98922391A patent/EP0981346A1/en not_active Withdrawn
- 1998-05-14 AU AU74949/98A patent/AU731690B2/en not_active Ceased
- 1998-05-14 PL PL98336764A patent/PL336764A1/xx unknown
- 1998-05-14 ZA ZA984084A patent/ZA984084B/xx unknown
- 1998-05-14 WO PCT/US1998/010113 patent/WO1998051305A1/en not_active Application Discontinuation
- 1998-05-14 KR KR1019997010511A patent/KR20010012556A/ko not_active Application Discontinuation
- 1998-05-14 BR BR9809120-4A patent/BR9809120A/pt not_active IP Right Cessation
- 1998-05-14 IL IL13212598A patent/IL132125A0/xx unknown
-
1999
- 1999-09-10 IS IS5177A patent/IS5177A/is unknown
- 1999-11-12 NO NO995549A patent/NO995549D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL132125A0 (en) | 2001-03-19 |
JP2001525827A (ja) | 2001-12-11 |
ZA984084B (en) | 1998-11-20 |
AU731690B2 (en) | 2001-04-05 |
KR20010012556A (ko) | 2001-02-15 |
NO995549L (no) | 1999-11-12 |
WO1998051305A1 (en) | 1998-11-19 |
NO995549D0 (no) | 1999-11-12 |
PL336764A1 (en) | 2000-07-17 |
CA2282473A1 (en) | 1998-11-19 |
HUP0003397A2 (hu) | 2002-01-28 |
EP0981346A1 (en) | 2000-03-01 |
AU7494998A (en) | 1998-12-08 |
US5874454A (en) | 1999-02-23 |
IS5177A (is) | 1999-09-10 |
HUP0003397A3 (en) | 2002-02-28 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1908 DE 31/07/2007. |