BR9805014A - Inibidores de metaloproteinase, processo para sua preparação e composições farmacêuticas contendo os mesmos - Google Patents
Inibidores de metaloproteinase, processo para sua preparação e composições farmacêuticas contendo os mesmosInfo
- Publication number
- BR9805014A BR9805014A BR9805014-1A BR9805014A BR9805014A BR 9805014 A BR9805014 A BR 9805014A BR 9805014 A BR9805014 A BR 9805014A BR 9805014 A BR9805014 A BR 9805014A
- Authority
- BR
- Brazil
- Prior art keywords
- same
- hydrogen atom
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003475 metalloproteinase inhibitor Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005553 heteroaryloxy group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004952 trihaloalkoxy group Chemical group 0.000 abstract 1
- 125000004385 trihaloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9714278A FR2771095B1 (fr) | 1997-11-14 | 1997-11-14 | Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9805014A true BR9805014A (pt) | 2001-04-24 |
Family
ID=9513364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9805014-1A BR9805014A (pt) | 1997-11-14 | 1998-11-13 | Inibidores de metaloproteinase, processo para sua preparação e composições farmacêuticas contendo os mesmos |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6066633A (es) |
| EP (1) | EP0916671B1 (es) |
| JP (1) | JPH11209378A (es) |
| CN (1) | CN1217332A (es) |
| AT (1) | ATE212634T1 (es) |
| AU (1) | AU740313B2 (es) |
| BR (1) | BR9805014A (es) |
| CA (1) | CA2254152C (es) |
| DE (1) | DE69803648T2 (es) |
| DK (1) | DK0916671T3 (es) |
| ES (1) | ES2172101T3 (es) |
| FR (1) | FR2771095B1 (es) |
| HU (1) | HUP9802645A3 (es) |
| NO (1) | NO311723B1 (es) |
| NZ (1) | NZ332803A (es) |
| PL (1) | PL329674A1 (es) |
| PT (1) | PT916671E (es) |
| ZA (1) | ZA9810411B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2821842B1 (fr) * | 2001-03-07 | 2003-05-09 | Servier Lab | Nouveaux derives d'inhibiteurs de mettalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PE20030701A1 (es) * | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
| ITMI20071163A1 (it) * | 2007-06-08 | 2008-12-09 | C4T S C A R L | Arilsolfonammidi dela beta-carbolina metodo per prepararle e composizione che le comprende |
| CN104387382A (zh) | 2008-03-24 | 2015-03-04 | 梅迪维新技术公司 | 吡啶并[3,4-b]吲哚和应用方法 |
| CN101597289B (zh) * | 2008-06-02 | 2011-09-21 | 首都医科大学 | 2-色氨酰-β-四氢咔啉-3-甲酰基氨基酸苄酯及其制备方法和应用 |
| JP5791611B2 (ja) * | 2009-09-23 | 2015-10-07 | メディベイション テクノロジーズ， インコーポレイテッド | ピリド［３，４−ｂ］インドールおよび使用方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5663178A (en) * | 1995-02-06 | 1997-09-02 | Eli Lilly And Company | Tetrahydro-beta carbolines |
| PL186869B1 (pl) * | 1995-11-13 | 2004-03-31 | Hoechst Ag | Nowe heterocykliczne N-podstawione pochodne kwasów alfa-iminohydroksamowych i karboksylowych, sposób ich wytwarzania, środek farmaceutyczny i ich zastosowanie |
| FR2748026B1 (fr) * | 1996-04-26 | 1998-06-05 | Adir | Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
1997
- 1997-11-14 FR FR9714278A patent/FR2771095B1/fr not_active Expired - Fee Related
-
1998
- 1998-11-10 NO NO19985239A patent/NO311723B1/no unknown
- 1998-11-12 CA CA002254152A patent/CA2254152C/fr not_active Expired - Fee Related
- 1998-11-13 DK DK98402806T patent/DK0916671T3/da active
- 1998-11-13 DE DE69803648T patent/DE69803648T2/de not_active Expired - Fee Related
- 1998-11-13 AT AT98402806T patent/ATE212634T1/de not_active IP Right Cessation
- 1998-11-13 NZ NZ332803A patent/NZ332803A/xx unknown
- 1998-11-13 BR BR9805014-1A patent/BR9805014A/pt not_active IP Right Cessation
- 1998-11-13 US US09/191,323 patent/US6066633A/en not_active Expired - Fee Related
- 1998-11-13 CN CN98122312A patent/CN1217332A/zh active Pending
- 1998-11-13 ZA ZA9810411A patent/ZA9810411B/xx unknown
- 1998-11-13 PT PT98402806T patent/PT916671E/pt unknown
- 1998-11-13 ES ES98402806T patent/ES2172101T3/es not_active Expired - Lifetime
- 1998-11-13 PL PL98329674A patent/PL329674A1/xx unknown
- 1998-11-13 HU HU9802645A patent/HUP9802645A3/hu unknown
- 1998-11-13 EP EP98402806A patent/EP0916671B1/fr not_active Expired - Lifetime
- 1998-11-13 AU AU92377/98A patent/AU740313B2/en not_active Ceased
- 1998-11-13 JP JP10323208A patent/JPH11209378A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9802645A2 (hu) | 1999-07-28 |
| JPH11209378A (ja) | 1999-08-03 |
| PL329674A1 (en) | 1999-05-24 |
| US6066633A (en) | 2000-05-23 |
| FR2771095B1 (fr) | 1999-12-17 |
| EP0916671A1 (fr) | 1999-05-19 |
| ZA9810411B (en) | 1999-05-24 |
| ATE212634T1 (de) | 2002-02-15 |
| EP0916671B1 (fr) | 2002-01-30 |
| NO985239L (no) | 1999-05-18 |
| CA2254152A1 (fr) | 1999-05-14 |
| AU740313B2 (en) | 2001-11-01 |
| NO985239D0 (no) | 1998-11-10 |
| CA2254152C (fr) | 2003-04-08 |
| HU9802645D0 (en) | 1999-01-28 |
| CN1217332A (zh) | 1999-05-26 |
| NZ332803A (en) | 1999-05-28 |
| AU9237798A (en) | 1999-06-03 |
| PT916671E (pt) | 2002-06-28 |
| NO311723B1 (no) | 2002-01-14 |
| DK0916671T3 (da) | 2002-03-25 |
| HUP9802645A3 (en) | 2000-01-28 |
| FR2771095A1 (fr) | 1999-05-21 |
| DE69803648D1 (de) | 2002-03-14 |
| ES2172101T3 (es) | 2002-09-16 |
| DE69803648T2 (de) | 2002-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: LES LABORATOIRES SERVIER (FR) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A , 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1872 DE 21/11/2006. |