BR9800956A - Composição farmacêutica que age por inibição das serinas proteases, e, medicamento - Google Patents
Composição farmacêutica que age por inibição das serinas proteases, e, medicamentoInfo
- Publication number
- BR9800956A BR9800956A BR9800956-7A BR9800956A BR9800956A BR 9800956 A BR9800956 A BR 9800956A BR 9800956 A BR9800956 A BR 9800956A BR 9800956 A BR9800956 A BR 9800956A
- Authority
- BR
- Brazil
- Prior art keywords
- acts
- pharmaceutical composition
- equal
- serine proteases
- medicine
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 102000012479 Serine Proteases Human genes 0.000 title abstract 2
- 108010022999 Serine Proteases Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- -1 AND Substances 0.000 abstract 1
- 101100439662 Arabidopsis thaliana CHR5 gene Proteins 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 150000001735 carboxylic acids Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003355 serines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
- C07F9/4012—Esters of acyclic acids which can have further substituents on alkyl substituted by B, Si, P or a metal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9703793A FR2761075B1 (fr) | 1997-03-24 | 1997-03-24 | Nouveaux composes a base de silicium biologiquement actifs et leurs applications therapeutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9800956A true BR9800956A (pt) | 2001-03-13 |
Family
ID=9505261
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9800956A BRPI9800956B8 (pt) | 1997-03-24 | 1998-03-24 | composição terapêutica que age por inibição das serinas proteases |
BR9800956-7A BR9800956A (pt) | 1997-03-24 | 1998-03-24 | Composição farmacêutica que age por inibição das serinas proteases, e, medicamento |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9800956A BRPI9800956B8 (pt) | 1997-03-24 | 1998-03-24 | composição terapêutica que age por inibição das serinas proteases |
Country Status (12)
Country | Link |
---|---|
US (1) | US6001389A (pt) |
EP (1) | EP0870504B1 (pt) |
JP (1) | JPH10279484A (pt) |
AR (1) | AR011998A1 (pt) |
AT (1) | ATE290538T1 (pt) |
BR (2) | BRPI9800956B8 (pt) |
CA (1) | CA2234500C (pt) |
DE (1) | DE69829236T2 (pt) |
DK (1) | DK0870504T3 (pt) |
ES (1) | ES2239384T3 (pt) |
FR (1) | FR2761075B1 (pt) |
PT (1) | PT870504E (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2799758B1 (fr) | 1999-10-15 | 2002-05-17 | Exsymol Sa | Complexe a base d'acide orthosilicique biologiquement assimilable, se presentant sous forme solide, stable et concentree, et procede de preparation |
CA2456025C (en) * | 2001-08-29 | 2011-11-22 | Ricardo A.P. De Carvalho | An implantable and sealable system for unidirectional delivery of therapeutic agents to tissues |
EP1583765A4 (en) * | 2002-11-18 | 2008-03-26 | Grenpharma Llc | COMPOSITIONS FOR THE TREATMENT AND / OR PREVENTION OF DISEASES CHARACTERIZED BY THE PRESENCE OF METALLIC IONS |
US7595308B2 (en) | 2002-11-18 | 2009-09-29 | Grenpharma Llc | Compositions for treating and/or preventing diseases characterized by the presence of metal ions |
EP1812013A1 (en) * | 2004-10-22 | 2007-08-01 | Grenpharma LLC | Compositions for treating and/or preventing diseases characterized by the presence of the metal ions |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1090210B (de) * | 1956-05-31 | 1960-10-06 | Gen Electric | Verfahren zur Herstellung von Phosphonsaeureesterreste enthaltenden Organosiliciumverbindungen |
FR6871M (pt) * | 1966-12-23 | 1969-04-14 | ||
US3914416A (en) * | 1966-12-23 | 1975-10-21 | Exsymol Sa | Certain monomethyl trisilanol mannuronate complexes for treating cellulitis |
FR2610522B1 (fr) * | 1987-02-06 | 1989-08-18 | Gueyne Jean | Produit therapeutique a base de derives organiques du silicium |
JPH0532683A (ja) * | 1991-07-29 | 1993-02-09 | Sanwa Kagaku Kenkyusho Co Ltd | 有機ゲルマニウム並びに有機珪素化合物、その製法及び用途 |
FR2725208B1 (fr) * | 1994-09-30 | 1996-11-29 | Exsymol Sa | Procede de preparation de composes de silicium biologiquement actifs sous forme concentree |
FR2725207B1 (fr) * | 1994-09-30 | 1996-11-29 | Exsymol Sa | Composes a base de silicium biologiquement actifs, leurs applications therapeutiques et cosmetiques |
-
1997
- 1997-03-24 FR FR9703793A patent/FR2761075B1/fr not_active Expired - Fee Related
-
1998
- 1998-03-18 CA CA002234500A patent/CA2234500C/fr not_active Expired - Fee Related
- 1998-03-19 JP JP10070367A patent/JPH10279484A/ja active Pending
- 1998-03-23 AR ARP980101309A patent/AR011998A1/es not_active Application Discontinuation
- 1998-03-23 EP EP98480017A patent/EP0870504B1/fr not_active Expired - Lifetime
- 1998-03-23 PT PT98480017T patent/PT870504E/pt unknown
- 1998-03-23 DE DE69829236T patent/DE69829236T2/de not_active Expired - Fee Related
- 1998-03-23 ES ES98480017T patent/ES2239384T3/es not_active Expired - Lifetime
- 1998-03-23 DK DK98480017T patent/DK0870504T3/da active
- 1998-03-23 AT AT98480017T patent/ATE290538T1/de active
- 1998-03-24 US US09/046,511 patent/US6001389A/en not_active Expired - Lifetime
- 1998-03-24 BR BRPI9800956A patent/BRPI9800956B8/pt unknown
- 1998-03-24 BR BR9800956-7A patent/BR9800956A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0870504A2 (fr) | 1998-10-14 |
ATE290538T1 (de) | 2005-03-15 |
EP0870504B1 (fr) | 2005-03-09 |
JPH10279484A (ja) | 1998-10-20 |
CA2234500A1 (fr) | 1998-09-24 |
PT870504E (pt) | 2005-07-29 |
ES2239384T3 (es) | 2005-09-16 |
US6001389A (en) | 1999-12-14 |
DK0870504T3 (da) | 2005-07-18 |
DE69829236D1 (de) | 2005-04-14 |
EP0870504A3 (fr) | 2002-09-11 |
BRPI9800956B8 (pt) | 2021-05-25 |
CA2234500C (fr) | 2009-08-25 |
FR2761075B1 (fr) | 1999-06-11 |
BRPI9800956B1 (pt) | 2018-09-11 |
FR2761075A1 (fr) | 1998-09-25 |
AR011998A1 (es) | 2000-09-13 |
DE69829236T2 (de) | 2006-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART. 37, INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA ( ART. 8O COMBINADO COM O ART. 13 DA LPI 9279/96). |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 16A ANUIDADE. |
|
B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO DE EXIGENCIA 6.6 POR TER SIDO INDEVIDA RRF. RPI 2318 |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/09/2018, OBSERVADAS AS CONDICOES LEGAIS. |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/03/1998 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 24/03/2018 |