BR9712406A - Composições farmacêuticas, contendo derivados de n-sufonil indolina - Google Patents

Composições farmacêuticas, contendo derivados de n-sufonil indolina

Info

Publication number
BR9712406A
BR9712406A BR9712406-0A BR9712406A BR9712406A BR 9712406 A BR9712406 A BR 9712406A BR 9712406 A BR9712406 A BR 9712406A BR 9712406 A BR9712406 A BR 9712406A
Authority
BR
Brazil
Prior art keywords
ionic hydrophilic
pharmaceutical compositions
surfactant
amphiphilic
sufonil
Prior art date
Application number
BR9712406-0A
Other languages
English (en)
Inventor
Jean-Claude Gautier
Simon John Fuller
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of BR9712406A publication Critical patent/BR9712406A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES FARMACêUTICAS, CONTENDO DERIVADOS DE N-SULFONIL INDOLINA"<D>. A presente invenção refere-se a um sistema solubilizante/estabilizante anidro, emulsionável ou microemulsionável na água, para solubilização dos derivados hidrófobos, de N-sulfonil indolina de fórmula (I), caracterizado pelo fato de compreender um ou vários constituintes escolhidos dentre compostos anfífilos, agentes tensoativos hidrófilos não-iónicos e compostos hidrófilos não-iónicos dotados, ao mesmo tempo, de propriedades anfífilas e tensoativas, naturalmente que esse sistema compreende seja pelo menos uma mistura de um composto anfífilo e de um agente tensoativo hidrófilo não-iónico, seja pelo menos um composto hidrófilo não-iónico dotado ao mesmo tempo de propriedades tensoativas e anfífilas.
BR9712406-0A 1996-12-05 1997-12-04 Composições farmacêuticas, contendo derivados de n-sufonil indolina BR9712406A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9614957A FR2756736B1 (fr) 1996-12-05 1996-12-05 Compositions pharmaceutiques contenant des derives de n-sulfonyl indoline
PCT/FR1997/002210 WO1998024430A1 (fr) 1996-12-05 1997-12-04 Compositions pharmaceutiques contenant des derives de n-sulfonyl indoline

Publications (1)

Publication Number Publication Date
BR9712406A true BR9712406A (pt) 1999-08-31

Family

ID=9498376

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9712406-0A BR9712406A (pt) 1996-12-05 1997-12-04 Composições farmacêuticas, contendo derivados de n-sufonil indolina

Country Status (25)

Country Link
EP (1) EP0941090A1 (pt)
JP (1) JP2000507618A (pt)
KR (1) KR20000069308A (pt)
CN (1) CN1239887A (pt)
AR (1) AR009651A1 (pt)
AU (1) AU716575B2 (pt)
BR (1) BR9712406A (pt)
CA (1) CA2273990A1 (pt)
CO (1) CO4910129A1 (pt)
DZ (1) DZ2362A1 (pt)
EE (1) EE9900206A (pt)
FR (1) FR2756736B1 (pt)
HU (1) HUP0001386A3 (pt)
ID (1) ID23373A (pt)
IL (1) IL129936A0 (pt)
IS (1) IS5062A (pt)
MY (1) MY132819A (pt)
NO (1) NO992724L (pt)
NZ (1) NZ335750A (pt)
RU (1) RU2174394C2 (pt)
SK (1) SK75599A3 (pt)
TR (1) TR199901702T2 (pt)
WO (1) WO1998024430A1 (pt)
YU (1) YU23099A (pt)
ZA (1) ZA9710919B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2786486B3 (fr) * 1998-11-16 2000-12-08 Sanofi Sa Procede de preparation du (2s)-1-[(2r,3s)-5-chloro-3-(2- chlorophenyl)-1-(3,4-dimethoxy benzenesulfonyl)-3-hydroxy- 2,3-dihydro-1h-indole-2-carbonyl]pyrrolidine-2-carboxamide, de ses solvats et/ou hydrates
DE19913692A1 (de) * 1999-03-25 2000-09-28 Basf Ag Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen
US6437006B1 (en) 1999-09-27 2002-08-20 American Cyanamid Company Pharmaceutical carrier formulation
WO2001034119A2 (en) 1999-11-12 2001-05-17 Abbott Laboratories Inhibitors of crystallization in a solid dispersion
FR2805992A1 (fr) * 2000-03-08 2001-09-14 Sanofi Synthelabo Compositions pharmaceutiques orales contenant des derives de n-sulfonylindoline
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
ITMI20011338A1 (it) 2001-06-26 2002-12-26 Farmatron Ltd Composizioni farmaceutiche orali a rilascio immediato del principio attivo
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
UA119324C2 (uk) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
KR102139339B1 (ko) * 2013-06-24 2020-07-29 주식회사 엘지생활건강 인돌 화합물을 포함하는 용해도가 개선된 화장료 조성물
KR102139338B1 (ko) * 2013-06-24 2020-07-29 주식회사 엘지생활건강 인돌 화합물을 포함하는 용해도가 개선된 화장료 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3237814A1 (de) * 1982-10-12 1984-04-12 Warner-Lambert Co., 07950 Morris Plains, N.J. Wasserfreie emulsionen und verwendung derselben
FR2679903B1 (fr) * 1991-08-02 1993-12-03 Elf Sanofi Derives de la n-sulfonyl indoline portant une fonction amidique, leur preparation, les compositions pharmaceutiques en contenant.

Also Published As

Publication number Publication date
ZA9710919B (en) 1999-06-04
CN1239887A (zh) 1999-12-29
DZ2362A1 (fr) 2002-12-28
FR2756736B1 (fr) 1999-03-05
EE9900206A (et) 1999-12-15
WO1998024430A1 (fr) 1998-06-11
HUP0001386A2 (hu) 2001-04-28
NO992724D0 (no) 1999-06-04
KR20000069308A (ko) 2000-11-25
FR2756736A1 (fr) 1998-06-12
ID23373A (id) 2000-04-20
AR009651A1 (es) 2000-04-26
IS5062A (is) 1999-06-01
AU716575B2 (en) 2000-03-02
TR199901702T2 (en) 1999-09-21
IL129936A0 (en) 2000-02-29
MY132819A (en) 2007-10-31
RU2174394C2 (ru) 2001-10-10
NZ335750A (en) 2001-06-29
JP2000507618A (ja) 2000-06-20
SK75599A3 (en) 2000-08-14
YU23099A (en) 1999-11-22
NO992724L (no) 1999-06-04
CA2273990A1 (fr) 1998-06-11
CO4910129A1 (es) 2000-04-24
AU5326298A (en) 1998-06-29
HUP0001386A3 (en) 2002-03-28
EP0941090A1 (fr) 1999-09-15

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Legal Events

Date Code Title Description
PC Transfer

Free format text: SANOFI-SYNTHELABO (FR)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A , 7A E 8A ANUIDADES.