BR9608003A - Nova forma de ácido (E)-3-[6-[[2,6-dicloro fenil) tio] metil]-3-(2-fenil etoxi)-2-piridinil ]-2-propenóico - Google Patents

Nova forma de ácido (E)-3-[6-[[2,6-dicloro fenil) tio] metil]-3-(2-fenil etoxi)-2-piridinil ]-2-propenóico

Info

Publication number
BR9608003A
BR9608003A BR9608003A BR9608003A BR9608003A BR 9608003 A BR9608003 A BR 9608003A BR 9608003 A BR9608003 A BR 9608003A BR 9608003 A BR9608003 A BR 9608003A BR 9608003 A BR9608003 A BR 9608003A
Authority
BR
Brazil
Prior art keywords
phenyl
pyridinyl
thio
methyl
propenoic
Prior art date
Application number
BR9608003A
Other languages
English (en)
Inventor
Victor Witold Jacewicz
Michael Anthony Harris
Richard Keith Anderson
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR9608003A publication Critical patent/BR9608003A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
BR9608003A 1995-04-21 1996-04-02 Nova forma de ácido (E)-3-[6-[[2,6-dicloro fenil) tio] metil]-3-(2-fenil etoxi)-2-piridinil ]-2-propenóico BR9608003A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9508137.8A GB9508137D0 (en) 1995-04-21 1995-04-21 Formulation
PCT/EP1996/001466 WO1996033174A1 (en) 1995-04-21 1996-04-02 New form of (e)-3-[6-[[(2,6-dichlorophenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propenoic acid

Publications (1)

Publication Number Publication Date
BR9608003A true BR9608003A (pt) 1999-01-05

Family

ID=10773317

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608003A BR9608003A (pt) 1995-04-21 1996-04-02 Nova forma de ácido (E)-3-[6-[[2,6-dicloro fenil) tio] metil]-3-(2-fenil etoxi)-2-piridinil ]-2-propenóico

Country Status (23)

Country Link
US (1) US6093828A (pt)
EP (1) EP0821673B1 (pt)
JP (1) JPH11503737A (pt)
KR (1) KR19990007900A (pt)
CN (1) CN1182418A (pt)
AT (1) ATE198883T1 (pt)
AU (1) AU707089B2 (pt)
BR (1) BR9608003A (pt)
CA (1) CA2218322A1 (pt)
CZ (1) CZ333797A3 (pt)
DE (1) DE69611670T2 (pt)
DK (1) DK0821673T3 (pt)
ES (1) ES2154818T3 (pt)
GB (1) GB9508137D0 (pt)
GR (1) GR3035494T3 (pt)
HU (1) HUP9801574A3 (pt)
NO (1) NO309767B1 (pt)
NZ (1) NZ307493A (pt)
PL (1) PL322897A1 (pt)
PT (1) PT821673E (pt)
TR (1) TR199701213T1 (pt)
WO (1) WO1996033174A1 (pt)
ZA (1) ZA963134B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9602675D0 (en) * 1996-02-09 1996-04-10 Smithkline Beecham Plc Process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006085A1 (en) * 1991-09-19 1993-04-01 Smithkline Beecham Corporation Pyridine compounds for treating leukotriene-related diseases
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
JP3181917B2 (ja) * 1992-06-30 2001-07-03 スミスクライン・ビーチャム・コーポレイション フェニルチオメチルピリジニルアルケノアート類の製造方法
GB9313145D0 (en) * 1993-06-25 1993-08-11 Smithkline Beecham Plc Process

Also Published As

Publication number Publication date
DE69611670D1 (en) 2001-03-01
TR199701213T1 (pt) 1998-03-21
PL322897A1 (en) 1998-03-02
JPH11503737A (ja) 1999-03-30
NO309767B1 (no) 2001-03-26
NO974840D0 (no) 1997-10-20
AU707089B2 (en) 1999-07-01
CA2218322A1 (en) 1996-10-24
AU5685996A (en) 1996-11-07
HUP9801574A3 (en) 1998-12-28
NZ307493A (en) 1998-07-28
EP0821673B1 (en) 2001-01-24
DE69611670T2 (de) 2001-08-23
ES2154818T3 (es) 2001-04-16
PT821673E (pt) 2001-05-31
CN1182418A (zh) 1998-05-20
HUP9801574A2 (hu) 1998-11-30
CZ333797A3 (cs) 1999-01-13
ZA963134B (en) 1997-02-14
US6093828A (en) 2000-07-25
NO974840L (no) 1997-10-20
DK0821673T3 (da) 2001-06-18
WO1996033174A1 (en) 1996-10-24
EP0821673A1 (en) 1998-02-04
GR3035494T3 (en) 2001-05-31
GB9508137D0 (en) 1995-06-07
KR19990007900A (ko) 1999-01-25
ATE198883T1 (de) 2001-02-15

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Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law