DK0821673T3 - Ny form af (E)-3-[6-[[2,6-dichlorphenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propensyre - Google Patents

Ny form af (E)-3-[6-[[2,6-dichlorphenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propensyre

Info

Publication number
DK0821673T3
DK0821673T3 DK96914877T DK96914877T DK0821673T3 DK 0821673 T3 DK0821673 T3 DK 0821673T3 DK 96914877 T DK96914877 T DK 96914877T DK 96914877 T DK96914877 T DK 96914877T DK 0821673 T3 DK0821673 T3 DK 0821673T3
Authority
DK
Denmark
Prior art keywords
phenylethoxy
dichlorophenyl
pyridinyl
thio
methyl
Prior art date
Application number
DK96914877T
Other languages
English (en)
Inventor
Victor Witold Jacewicz
Michael Anthony Harris
Richard Keith Anderson
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of DK0821673T3 publication Critical patent/DK0821673T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK96914877T 1995-04-21 1996-04-02 Ny form af (E)-3-[6-[[2,6-dichlorphenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propensyre DK0821673T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9508137.8A GB9508137D0 (en) 1995-04-21 1995-04-21 Formulation
PCT/EP1996/001466 WO1996033174A1 (en) 1995-04-21 1996-04-02 New form of (e)-3-[6-[[(2,6-dichlorophenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propenoic acid

Publications (1)

Publication Number Publication Date
DK0821673T3 true DK0821673T3 (da) 2001-06-18

Family

ID=10773317

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96914877T DK0821673T3 (da) 1995-04-21 1996-04-02 Ny form af (E)-3-[6-[[2,6-dichlorphenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propensyre

Country Status (23)

Country Link
US (1) US6093828A (da)
EP (1) EP0821673B1 (da)
JP (1) JPH11503737A (da)
KR (1) KR19990007900A (da)
CN (1) CN1182418A (da)
AT (1) ATE198883T1 (da)
AU (1) AU707089B2 (da)
BR (1) BR9608003A (da)
CA (1) CA2218322A1 (da)
CZ (1) CZ333797A3 (da)
DE (1) DE69611670T2 (da)
DK (1) DK0821673T3 (da)
ES (1) ES2154818T3 (da)
GB (1) GB9508137D0 (da)
GR (1) GR3035494T3 (da)
HU (1) HUP9801574A3 (da)
NO (1) NO309767B1 (da)
NZ (1) NZ307493A (da)
PL (1) PL322897A1 (da)
PT (1) PT821673E (da)
TR (1) TR199701213T1 (da)
WO (1) WO1996033174A1 (da)
ZA (1) ZA963134B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9602675D0 (en) * 1996-02-09 1996-04-10 Smithkline Beecham Plc Process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006085A1 (en) * 1991-09-19 1993-04-01 Smithkline Beecham Corporation Pyridine compounds for treating leukotriene-related diseases
CA2138955A1 (en) * 1992-06-30 1994-01-06 Robert A. Daines Process for making phenylthiomethylpyridinylalkenoates
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
GB9313145D0 (en) * 1993-06-25 1993-08-11 Smithkline Beecham Plc Process

Also Published As

Publication number Publication date
JPH11503737A (ja) 1999-03-30
NZ307493A (en) 1998-07-28
PT821673E (pt) 2001-05-31
CN1182418A (zh) 1998-05-20
AU5685996A (en) 1996-11-07
TR199701213T1 (da) 1998-03-21
ZA963134B (en) 1997-02-14
EP0821673A1 (en) 1998-02-04
PL322897A1 (en) 1998-03-02
DE69611670T2 (de) 2001-08-23
GR3035494T3 (en) 2001-05-31
HUP9801574A2 (hu) 1998-11-30
AU707089B2 (en) 1999-07-01
NO309767B1 (no) 2001-03-26
NO974840L (no) 1997-10-20
US6093828A (en) 2000-07-25
EP0821673B1 (en) 2001-01-24
GB9508137D0 (en) 1995-06-07
WO1996033174A1 (en) 1996-10-24
NO974840D0 (no) 1997-10-20
ES2154818T3 (es) 2001-04-16
ATE198883T1 (de) 2001-02-15
DE69611670D1 (en) 2001-03-01
CA2218322A1 (en) 1996-10-24
KR19990007900A (ko) 1999-01-25
CZ333797A3 (cs) 1999-01-13
HUP9801574A3 (en) 1998-12-28
BR9608003A (pt) 1999-01-05

Similar Documents

Publication Publication Date Title
DK0509019T3 (da) Behandling af humane retrovirale infektioner med 2',3'-dideoxyinosin
DK0833839T3 (da) Heterocykliske peptidylforbindelser, der er nyttige til behandling af thrombinrelaterede sygdomme
NO303223B1 (no) AnalogifremgangsmÕte for fremstilling av terapeutisk aktive bis-benzo- eller benzopyridocykloheptapiperiden-, piperidyliden- og piperazinforbindelser
DK0882021T3 (da) Nye phenanthridiner
FR12C0004I2 (fr) Anticorps contre l'antigene ctla-4 humain et utilisation
ID22042A (id) Benzonaftiridin sebagai pengobatan cabang tenggorokan
AU5648496A (en) Pyrazolo-(1,5a)pyrimidines, their preparation and their use
DE69120287T2 (de) Aminosulfonylharnstoff-acat-inhibitoren
RS50129B (sr) Optički aktivan derivat piridil-4h-1,2,4-oksadiazina i njegova upotreba u proizvodnji lekova za tretiranje vaskularnih bolesti
DK0821673T3 (da) Ny form af (E)-3-[6-[[2,6-dichlorphenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propensyre
PT783495E (pt) Derivados de quinoxalina uteis em terapia
TR199801184T2 (xx) Analjezik tesirli yeni bile�ikler.
PT775143E (pt) Novos derivados de 3h-2,3-benzodiazepina 3-substituidos sua preparacao e utilizacao
KR890006621A (ko) 항불안제
BR0016941A (pt) Derivados de aminometil-fenil-ciclohexanona
DK0537313T3 (da) Arylalkylestere af 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracencarboxylsyre med terapeutisk aktivitet
ATE216702T1 (de) Silylierungsprocess
MX9708089A (es) Compuestos.
FR2657005B1 (fr) Systeme d'enclouage pour le traitement des fractures notamment du type cervico-trochanteriennes et pertrochanteriennes.
FR2427822A1 (fr) Medicament pour le traitement des maladies circulatoires, a base de 5-methyl-7-dimethylamino-s-triazolo (1,5-a) pyrimidine
NO974687D0 (no) Kondenserte <beta>-carboliner
UA7134C2 (uk) Спосіб терапевтичної дії на біологічні об'єкти та пристрій для його здійснення
SE8900834D0 (sv) New uses of 4-(3-phosphono-2-propenyl)-2-piperazinecarboxylic acid
TH23382A (th) กรรมวิธีสำหรับสังเคราะห์ซับสทิทิวเทดซัลฟอกไซด์
SU1829367A1 (ru) 5-(1-гидрокси-1-метоксикарбонил-2,2,2-трифторэтил)-8-трибутилоловооксихинолин, проявляющий антистафилококковую активность